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ROCEPHIN® (ceftriaxone sodium) FOR INJECTION Rx only To
ROCEPHIN® (ceftriaxone sodium) FOR INJECTION Rx only To

... INDICATIONS AND USAGE Before instituting treatment with Rocephin, appropriate specimens should be obtained for isolation of the causative organism and for determination of its susceptibility to the drug. Therapy may be instituted prior to obtaining results of susceptibility testing. To reduce the de ...
Seizures
Seizures

... A Prodrug of phenytoin, more soluble, for parenteral use. rapidly converted to in the body. ...
Universidade de Lisboa Faculdade de Farmácia Assessing drug
Universidade de Lisboa Faculdade de Farmácia Assessing drug

... Using a global web-based survey, we identified that medicines compendia are the leading information source among healthcare professionals, followed by Internet and scientific journals. Out of 193 countries in the world, 132 answered the survey, with 84 of them reporting that a national compendium is ...
MRI INTERVENTIONS, INC.
MRI INTERVENTIONS, INC.

... Forward Looking Statements Certain statements in this presentation may constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements often can be identified by words such as “a ...
LSEHWP39
LSEHWP39

... (VPA), and carbamazepine (CBZ), also referred as ‘older generation AEDs’, some of which have been available since the 1940s. The new AEDs possess some novel characteristics, fuelling expectations that they may be more suitable for managing difficult-to-treat epilepsy syndromes, more easily tolerable ...
Methadone Poisoning
Methadone Poisoning

... publications of Substance Abuse and Mental Health Services Administration (SAMHSA – an agency of U.S. Dept. of Health and Human Services). Methadone is a synthetic opioid and was developed in Germany in 1937. Methadone was introduced into the United States in 1947 by Eli Lilly and Company as an anal ...
Dose-finding and 24-h monitoring for efficacy and safety of E.M. App
Dose-finding and 24-h monitoring for efficacy and safety of E.M. App

... history of an acute respiratory episode within 2 weeks before the study; were unable to stop using antibiotics, bronchodilators, mucolytics or expectorant drugs within 1 week prior to their first intake of the study drug; had a history of allergy to ACC or related drugs; were unable to use an MDI co ...
References - Specialist Pharmacy Service
References - Specialist Pharmacy Service

of aspirin
of aspirin

... protein biosynthesis and thus cannot regenerate the cyclooxygenase enzyme. • In practical terms, this means that a single dose of aspirin will inhibit the platelet cyclooxygenase for the life of the platelet (8 to 11 days); in human beings, a daily dose of aspirin as small as 40 mg is sufficient to ...
TOPAMAX® - Janssen
TOPAMAX® - Janssen

... observed. Following single dose administration, the volume of distribution varies inversely with dose. The mean apparent volume of distribution has been measured as 0.8 - 0.55 L/kg for a single dose range of 100 mg to 1200 mg. There is an effect of gender on the volume of distribution. Values for fe ...
ALFENTANIL 500 MICROGRAMS / ML SOLUTION FOR INJECTION
ALFENTANIL 500 MICROGRAMS / ML SOLUTION FOR INJECTION

... Use in elderly and debilitated patients: Lower or less frequent dosing may be required owing to a longer half-life of alfentanil in this age group (dilution may be helpful). In spontaneously breathing patients, the initial bolus dose should be given slowly over about 30 seconds (dilution may be help ...
Bicompartmental model Kinetic disposition of a parent drug and its
Bicompartmental model Kinetic disposition of a parent drug and its

... Visual inspection of these different fittings indicates severe misfits. It also suggests that none of the classical compartmental models will be able to fit these data and so we decided to carry out only an NCA of the metabolite plasma kinetics. Before proceeding to this NCA, add a time point to the ...
Public Assessment Report Scientific discussion Tracydal 20 mg, film
Public Assessment Report Scientific discussion Tracydal 20 mg, film

... objective of the ASMF procedure, commonly known as the European Drug Master File (EDMF) procedure, is to allow valuable confidential intellectual property or ‘know-how’ of the manufacturer of the active substance (ASM) to be protected, while at the same time allowing the applicant or marketing autho ...
The role of funding and policies on cancer drugs (report)
The role of funding and policies on cancer drugs (report)

... Source: World Health Organisation, The Global Burden of Disease: 2004 update. WHO 2008. ......................... 3 Figure 1.2 ............................................................................................................................................................... 8 Global R&D ...
The Potential of Cyclodextrins as Novel Active Pharmaceutical
The Potential of Cyclodextrins as Novel Active Pharmaceutical

... Cyclodextrins (CDs) are chemical entities of natural origin, which are derived from bacterial degradation of starch through the metabolic action of cyclodextrin glycosyl transferase enzyme (GCTase). This peculiar enzyme is present in several species of alkalophilic bacillus species (e.g., Bacillus m ...
hydromorphone hydrochloride ciir
hydromorphone hydrochloride ciir

... Gastrointestinal System: Nausea, and vomiting occur infrequently; they are more frequent in ambulatory than in recumbent patients. The antiemetic phenothiazines are useful in suppressing these effects; however, some phenothiazine derivatives seem to be antianalgesic and to increase the amount of nar ...
Evaluation of Quality Control Parameters of Two Brands of
Evaluation of Quality Control Parameters of Two Brands of

... therapeutically active and standard drug. It can be achieved by following some parameters that are specified in the respective monograph of the drug. This research work was aimed to investigate the quality control parameters of two brands of diazepam (Seduxen®, Sedil®) which are available in market. ...
Chapter 19 - The Red Zone
Chapter 19 - The Red Zone

... effects of extravasated vasopressors such as norepinephrine or epinephrine  Restores blood flow and prevents tissue necrosis ...
An investigation of the effects of fulvic and humic acids... the absorption of selected drugs, vitamins and minerals
An investigation of the effects of fulvic and humic acids... the absorption of selected drugs, vitamins and minerals

... for each test compound was noted, the extent of the absorption increase or decrease was compound specific. The changes in absorption observed could be attributed to changes in compound solubility and mechanism of transport across the intestinal membrane once in complex. Drugs and vitamins were seen ...
Physician`s Labeling Rule_Content
Physician`s Labeling Rule_Content

... CYP3A4, such as ketoconazole, while taking LUNESTA. Downward dose adjustment is also recommended when LUNESTA is administered with agents having known CNS-depressant effects. Use in Patients with Depression Sedative/hypnotic drugs should be administered with caution to patients exhibiting signs and ...
Key Test Findings Affiliated Genetics
Key Test Findings Affiliated Genetics

... Careful titration is recommended with monitoring for toxicity until a favorable response is achieved.  In children and adolescents up to 70 kg body weight, atomoxetine should be initiated at standard dosing of 0.5 mg/kg/day and only increased to the usual target dose of 1.2 mg/kg/day if symptoms fai ...
ANTICONVULSANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CALOTROPIS GIGANTEA IN
ANTICONVULSANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CALOTROPIS GIGANTEA IN

... MES predicts activity against generalised tonic clonic and cortical focal seizures while PTZ tests activity against petitmal epilepsy or absence seizures. The reduction in duration of hind limb extensor phase and delay in the latency of seizures are considered as important parameters to assess the e ...
Sinemet® CR Product Monograph
Sinemet® CR Product Monograph

... that these events are NOT limited to initiation of therapy. Patients should also be advised that sudden onset of sleep has occurred without warning signs and should be specifically asked about factors that may increase the risk with SINEMET® CR such as concomitant medications or the presence of slee ...
Protease inhibitor plasma concentrations in HIV antiretroviral therapy
Protease inhibitor plasma concentrations in HIV antiretroviral therapy

... are included in every analytical run (intra-laboratory quality control), and this is the practice in most published methods [II, 44, 45, 51-53]. The use of internal standards, which are added to every sample, to enhance performance is also applied in some of the published methods, but with more than ...
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED

... of an augmentation of 12.5 mg quetiapine once a day suggests that the patient may have been sensitized by the initial trial of fluoxetine and trazodone with quetiapine augmentation. In our case, this condition could be due to only low dose of quetiapine, but also could be related to latent effect of ...
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Prescription costs

Prescription costs are a common health care cost for many people and also the source of considerable economic hardship for some. These costs are sometimes referred to as out-of-pocket prescription costs, since for those with insurance, the total cost of their prescriptions may include expenses covered by a third party, such as an insurance company, as well as the individual. Out-of-pocket prescription costs include deductibles, co-payments, and upper limits in coverage.
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