Dosage Adjustment for Cytotoxics in Hepatic Impairment
... Pharmion – In the 3 NCI studies involving azacitadine there was no significant increase in adverse reactions in patients with hepatic impairment compared with those with normal hepatic function. However the drug should be used with caution as it is metabolised by hepatic enzymes. In addition there i ...
... Pharmion – In the 3 NCI studies involving azacitadine there was no significant increase in adverse reactions in patients with hepatic impairment compared with those with normal hepatic function. However the drug should be used with caution as it is metabolised by hepatic enzymes. In addition there i ...
Zimax
... susceptible organisms and thus interferes with microbial protein synthesis. Following oral administration in humans, Zimax® (Azithromycin) is rapidly absorbed and widely distributed throughout the body ; bioavailability is approximately 37%. The time taken to peak plasma levels is 2-3 hours. However ...
... susceptible organisms and thus interferes with microbial protein synthesis. Following oral administration in humans, Zimax® (Azithromycin) is rapidly absorbed and widely distributed throughout the body ; bioavailability is approximately 37%. The time taken to peak plasma levels is 2-3 hours. However ...
Cephalosporins
... Many cephalosporins are administered parenterally because they aren’t absorbed from the GI tract. Some cephalosporins are absorbed from the GI tract and can be administered orally, but food usually decreases the absorption rate of these oral cephalosporins, though not the amount absorbed. Two cephal ...
... Many cephalosporins are administered parenterally because they aren’t absorbed from the GI tract. Some cephalosporins are absorbed from the GI tract and can be administered orally, but food usually decreases the absorption rate of these oral cephalosporins, though not the amount absorbed. Two cephal ...
consumer medicine information
... There have been reports of hepatic dysfunction, including increased liver enzymes, and hepatocellular and/or cholestatic hepatitis, with or without jaundice occurring in patients receiving oral erythromycin products. Since erythromycin is principally excreted by the liver, caution should be exercise ...
... There have been reports of hepatic dysfunction, including increased liver enzymes, and hepatocellular and/or cholestatic hepatitis, with or without jaundice occurring in patients receiving oral erythromycin products. Since erythromycin is principally excreted by the liver, caution should be exercise ...
Module 2: Pharmacotherapy - UCLA Integrated Substance Abuse
... disorder. It is a dependency which is very difficult to resolve Relapse is extremely common. It is part of the process of resolving the dependence – much like giving up tobacco A principal health care objective is to get patients into treatment, help keep them in treatment, and to return them to ...
... disorder. It is a dependency which is very difficult to resolve Relapse is extremely common. It is part of the process of resolving the dependence – much like giving up tobacco A principal health care objective is to get patients into treatment, help keep them in treatment, and to return them to ...
ALDACTAZIDE
... Gynecomastia: Gynecomastia may develop with the use of spironolactone and physicians should be advised of its possible occurrence. The development of gynecomastia appears to be related to both dosage and duration of therapy and is normally reversible when the drug is discontinued. If gynecomastia de ...
... Gynecomastia: Gynecomastia may develop with the use of spironolactone and physicians should be advised of its possible occurrence. The development of gynecomastia appears to be related to both dosage and duration of therapy and is normally reversible when the drug is discontinued. If gynecomastia de ...
Paxil - GlaxoSmithKline
... anxiety, headache, tremor, confusion, diarrhea, nausea, vomiting and sweating) or other symptoms which may be of clinical significance [see ADVERSE REACTIONS, Adverse Events following Discontinuation of Treatment (or Dose Reduction)-Post-Marketing]. A gradual reduction in the dose rather than abrupt ...
... anxiety, headache, tremor, confusion, diarrhea, nausea, vomiting and sweating) or other symptoms which may be of clinical significance [see ADVERSE REACTIONS, Adverse Events following Discontinuation of Treatment (or Dose Reduction)-Post-Marketing]. A gradual reduction in the dose rather than abrupt ...
Treatment of myoclonic seizures
... Several open-label studies suggest that LTG is efficacious against all seizure types in patients with JME [11,12] . In a retrospective study that included 72 patients with JME, no significant differences in seizure control were found between VPA and LTG in either monotherapy or polytherapy [13] . Ho ...
... Several open-label studies suggest that LTG is efficacious against all seizure types in patients with JME [11,12] . In a retrospective study that included 72 patients with JME, no significant differences in seizure control were found between VPA and LTG in either monotherapy or polytherapy [13] . Ho ...
Guidelines for the regulation of herbal medicines in the South
... Governments in the South-East Asia Region are encouraging medical doctors to work with traditional practitioners at the hospital level, and to support research on TM. For example, in India there are 2860 hospitals providing Ayurvedic medicines. In Bhutan, in the national health centre, patients can ...
... Governments in the South-East Asia Region are encouraging medical doctors to work with traditional practitioners at the hospital level, and to support research on TM. For example, in India there are 2860 hospitals providing Ayurvedic medicines. In Bhutan, in the national health centre, patients can ...
Early phase PET research in the UK
... these are only produced by select academic PET centres. Moreover, some of the radiotracers sold by commercial companies are not available in all parts of the UK. There is a need to encourage commercial companies to increase number and availability of new (i.e. other than FDG) radiotracers. 7. There ...
... these are only produced by select academic PET centres. Moreover, some of the radiotracers sold by commercial companies are not available in all parts of the UK. There is a need to encourage commercial companies to increase number and availability of new (i.e. other than FDG) radiotracers. 7. There ...
Novel pharmacotherapeutic treatments for cocaine addiction R E V I E W
... underlying the putative anti-addictive properties of ibogaine. However, despite general agreement on the sites of activity of this medication, there remain some contradictory findings in regards to the action of ibogaine within the brain. For example, Baumann et al found that ibogaine and noribogain ...
... underlying the putative anti-addictive properties of ibogaine. However, despite general agreement on the sites of activity of this medication, there remain some contradictory findings in regards to the action of ibogaine within the brain. For example, Baumann et al found that ibogaine and noribogain ...
PAXIL PRODUCT MONOGRAPH
... anxiety, headache, tremor, confusion, diarrhea, nausea, vomiting and sweating) or other symptoms which may be of clinical significance [see ADVERSE REACTIONS, Adverse Events following Discontinuation of Treatment (or Dose Reduction)-Post-Marketing]. A gradual reduction in the dose rather than abrupt ...
... anxiety, headache, tremor, confusion, diarrhea, nausea, vomiting and sweating) or other symptoms which may be of clinical significance [see ADVERSE REACTIONS, Adverse Events following Discontinuation of Treatment (or Dose Reduction)-Post-Marketing]. A gradual reduction in the dose rather than abrupt ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... number of clinical studies suggest that spinal anaesthesia may be superior to general or epidural anaesthesia for certain patients and for certain surgical procedures. The endocrine-metabolic response to surgery appears to be blunted when spinal anaesthesia is employed compared to the response durin ...
... number of clinical studies suggest that spinal anaesthesia may be superior to general or epidural anaesthesia for certain patients and for certain surgical procedures. The endocrine-metabolic response to surgery appears to be blunted when spinal anaesthesia is employed compared to the response durin ...
united states district court
... of North Carolina from 1976 to 1977. I then served as a primary care physician in the National Health Service Corps of the U.S. Public Service in Monroe County, West Virginia from 1977 to 1979. I completed my residency at Case Western Reserve University from 1979 to 1981. I also completed a Robert W ...
... of North Carolina from 1976 to 1977. I then served as a primary care physician in the National Health Service Corps of the U.S. Public Service in Monroe County, West Virginia from 1977 to 1979. I completed my residency at Case Western Reserve University from 1979 to 1981. I also completed a Robert W ...
diclofenac - Endo Pharmaceuticals
... diclofenac. Postmarketing surveillance has reported cases of severe hepatic reactions, including liver necrosis, jaundice, fulminant hepatitis with and without jaundice, and liver failure. Some of these reported cases resulted in fatalities or liver transplantation. Physicians should measure transam ...
... diclofenac. Postmarketing surveillance has reported cases of severe hepatic reactions, including liver necrosis, jaundice, fulminant hepatitis with and without jaundice, and liver failure. Some of these reported cases resulted in fatalities or liver transplantation. Physicians should measure transam ...
... (Product Licence number: 20395/0011). This antibiotic is only available with a prescription. Doxycycline 100 mg Capsules contain the active ingredient doxycycline hyclate. Doxycycline works by preventing the microorganisms responsible for infection from making the proteins that they need to grow. No ...
results - Pakistan Journal of Pharmaceutical Sciences
... administration of double dose 3.0 mg/kg meloxicam for seven days to group C caused a significant (P<0.01) difference in Serum Urea level (55.73±0.86 mg/dl) on day 1 and persistent till day 3 (47.88±1.45 mg/dl), and day 5 (40.79±0.40 mg/dl) post drug administration. The mean value on day 10 was 35.38 ...
... administration of double dose 3.0 mg/kg meloxicam for seven days to group C caused a significant (P<0.01) difference in Serum Urea level (55.73±0.86 mg/dl) on day 1 and persistent till day 3 (47.88±1.45 mg/dl), and day 5 (40.79±0.40 mg/dl) post drug administration. The mean value on day 10 was 35.38 ...
Product Monograph
... Nursing Women: Animal studies have shown excretion of pilocarpine in breast milk at concentrations similar to those seen in plasma. It is not presently known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse re ...
... Nursing Women: Animal studies have shown excretion of pilocarpine in breast milk at concentrations similar to those seen in plasma. It is not presently known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse re ...
... administration period. More than 9300 persons were recommended to complete a minimum of 60 days of antibiotic prophylaxis against possible inhalational exposure to B. anthracis during 2001. Ciprofloxacin was recommended to most of those individuals for all or part of the prophylaxis regimen. Some pe ...
5-Fluorouracil encapsulated alginate beads for the treatment of
... Alginate beads containing 5-fluorouracil (5-FU) were prepared by the gelation of alginate with calcium cations. Alginate beads loaded with 5-FU were prepared at 1.0 and 2.0% (w/v) polymers. The effect of polymer concentration and the drug loading (1.0, 5.0 and 10%) on the release profile of 5-FU was ...
... Alginate beads containing 5-fluorouracil (5-FU) were prepared by the gelation of alginate with calcium cations. Alginate beads loaded with 5-FU were prepared at 1.0 and 2.0% (w/v) polymers. The effect of polymer concentration and the drug loading (1.0, 5.0 and 10%) on the release profile of 5-FU was ...
Selegiline transdermal system in major depressive disorder
... fixed-dose STS 6 mg/24 h was significantly more effective than placebo on the 17-item Hamilton Depression Rating Scale (HAM-D) and statistical separation from placebo was seen as early as week 1. Significantly more STS patients achieved a reduction of 50% or more in total HAM-D-17 scores (37.5 vs 22 ...
... fixed-dose STS 6 mg/24 h was significantly more effective than placebo on the 17-item Hamilton Depression Rating Scale (HAM-D) and statistical separation from placebo was seen as early as week 1. Significantly more STS patients achieved a reduction of 50% or more in total HAM-D-17 scores (37.5 vs 22 ...
Methadone-Drug Interactions
... certain circumstances (Leavitt and Krantz 2003). Researchers have reported relatively small but statistically significant QT interval increases among MMT patients, although the QT measurements generally remained within acceptable limits (Maremmani et al. 2005; Martell et al. 2005). Often, these hear ...
... certain circumstances (Leavitt and Krantz 2003). Researchers have reported relatively small but statistically significant QT interval increases among MMT patients, although the QT measurements generally remained within acceptable limits (Maremmani et al. 2005; Martell et al. 2005). Often, these hear ...
Routine analysis of amphetamine class drugs as their
... HPLC methods have been developed for the simultaneous analysis of other amphetamines that are abused extensively such as MDMA, MDA and MDEA. Recently Bogusz et al. reported an HPLC method for the simultaneous detection of these amines in urine as their phenylisothiocyanate derivatives using a diode ...
... HPLC methods have been developed for the simultaneous analysis of other amphetamines that are abused extensively such as MDMA, MDA and MDEA. Recently Bogusz et al. reported an HPLC method for the simultaneous detection of these amines in urine as their phenylisothiocyanate derivatives using a diode ...