Current and Potential Drugs for Treatment of Obesity
... “Corpulency, when in an extraordinary degree, may be reckoned a disease, as it in some measure obstructs the free exercise of the animal functions; and hath a tendency to shorten life, by paving the way to dangerous distempers.” Data collected in the United States by the National Center ...
... “Corpulency, when in an extraordinary degree, may be reckoned a disease, as it in some measure obstructs the free exercise of the animal functions; and hath a tendency to shorten life, by paving the way to dangerous distempers.” Data collected in the United States by the National Center ...
THE AMERICAN UNIVERSITY IN CAIRO School of Sciences and Engineering
... The release of curcumin from different alginate/MMT nanocomposites was studied in different biorelevent media: fast gastric (FaSSGF), fast intestinal (FaSSIF) and fed intestinal media (FeSSIF). The curcumin release in gastric media was negligible and this was attributed to its low solubility in thes ...
... The release of curcumin from different alginate/MMT nanocomposites was studied in different biorelevent media: fast gastric (FaSSGF), fast intestinal (FaSSIF) and fed intestinal media (FeSSIF). The curcumin release in gastric media was negligible and this was attributed to its low solubility in thes ...
File
... uses, and their side effects. • Know why and how lithium and other drugs are used in treating bipolar disorders. • Be familiar with antipsychotics and the drugs that prevent their side effects. • Define anxiety, learn its symptoms, and know the drugs used in its treatment. • Recognize the course and ...
... uses, and their side effects. • Know why and how lithium and other drugs are used in treating bipolar disorders. • Be familiar with antipsychotics and the drugs that prevent their side effects. • Define anxiety, learn its symptoms, and know the drugs used in its treatment. • Recognize the course and ...
Antiepileptic drugs for neuropathic pain and fibromyalgia
... How the intervention might work Different antiepileptic drugs will have different mechanisms of action, not all of which are likely to be well understood, especially in terms of how a particular drug produces pain relief in any particular individual with any particular chronic pain condition. Pain p ...
... How the intervention might work Different antiepileptic drugs will have different mechanisms of action, not all of which are likely to be well understood, especially in terms of how a particular drug produces pain relief in any particular individual with any particular chronic pain condition. Pain p ...
Public Assessment Report Mutual Recognition Procedure DALSAN
... The dosage should be set individually depending on nature and severity of the disease, as well as on the patient’s condition and age. The tablets should be taken as a whole, without chewing them, with a small volume of water once daily. Concomitant food intake does not influence the efficacy. Treatm ...
... The dosage should be set individually depending on nature and severity of the disease, as well as on the patient’s condition and age. The tablets should be taken as a whole, without chewing them, with a small volume of water once daily. Concomitant food intake does not influence the efficacy. Treatm ...
In silico methods in prediction of drug metabolism, mass
... more active and toxic species [8]. Toxicity, which is often related to metabolism, is a significant factor in the rejection of a lead molecule during drug development and the withdrawal of new drugs [9,10]. Determination of a drug’s metabolic stability, as well as identification of its major metabol ...
... more active and toxic species [8]. Toxicity, which is often related to metabolism, is a significant factor in the rejection of a lead molecule during drug development and the withdrawal of new drugs [9,10]. Determination of a drug’s metabolic stability, as well as identification of its major metabol ...
(PSD) July 2016 PBAC Meeting - (Word 86KB)
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
Implications of Recent Clinical Trials for the National Cholesterol
... Serum lipids at baseline were determined on nonfasting samples. Levels of LDL-C were measured by the direct LDL method.9 Average lipid values at baseline were total cholesterol 228 mg/dL, triglycerides 186 mg/dL (nonfasting), HDL-C 41 mg/dL, non-HDL-C 187 mg/dL, and direct LDL-C 131 mg/dL. In most o ...
... Serum lipids at baseline were determined on nonfasting samples. Levels of LDL-C were measured by the direct LDL method.9 Average lipid values at baseline were total cholesterol 228 mg/dL, triglycerides 186 mg/dL (nonfasting), HDL-C 41 mg/dL, non-HDL-C 187 mg/dL, and direct LDL-C 131 mg/dL. In most o ...
Medication Safety in the Neonatal Intensive Care Unit
... Medication Practices (ISMP) published a list of high-alert medications that can cause significant patient harm when used in error. In a recent study, administration of the high-alert medications described by ISMP has been shown to be a risk factor for harm in neonatal patients (Stavroudis et al., 20 ...
... Medication Practices (ISMP) published a list of high-alert medications that can cause significant patient harm when used in error. In a recent study, administration of the high-alert medications described by ISMP has been shown to be a risk factor for harm in neonatal patients (Stavroudis et al., 20 ...
Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
... important role in health and disease by modulating gene expression, and 4) siRNAs- these 18–25 nucleotide long duplexes are potent activators of the innate immune system that have been shown to initiate sequence-specific post-transcriptional gene silencing. Although all of these strategies can poten ...
... important role in health and disease by modulating gene expression, and 4) siRNAs- these 18–25 nucleotide long duplexes are potent activators of the innate immune system that have been shown to initiate sequence-specific post-transcriptional gene silencing. Although all of these strategies can poten ...
Riboflavin 0.1% (VibeX) for the treatment of keratoconus
... the literature [2] is 1/2,000 which is within the threshold used by the European Union to define a disease as rare disease (also referred to as an orphan disease) [6], and the incidence is 2 -- 3/100,000 [2], although many authors agree that in the coming years there will be an increase of these val ...
... the literature [2] is 1/2,000 which is within the threshold used by the European Union to define a disease as rare disease (also referred to as an orphan disease) [6], and the incidence is 2 -- 3/100,000 [2], although many authors agree that in the coming years there will be an increase of these val ...
Adverse_Events_White_Paper
... across therapeutic areas by ensuring that reviewers receive clinically relevant and meaningful analyses of patient safety for benefit-risk assessment. This white paper reflects recommendations that would lead to more consistent TFLs, but the recommendations should not be interpreted as “required” by ...
... across therapeutic areas by ensuring that reviewers receive clinically relevant and meaningful analyses of patient safety for benefit-risk assessment. This white paper reflects recommendations that would lead to more consistent TFLs, but the recommendations should not be interpreted as “required” by ...
Interventional Role of Piperazine Citrate in Barium Chloride Induced
... BaCl2 of 20mg/kg was used to induce arrhythmias in 21 Wistar rats of either sex. Five of the rats that were not treated with piperazine following BaCl administration died within one minute from ventricular fibrillation. Among the 10 rats with BaCl2-induced dysrhythmia, treated with piperazine, five ...
... BaCl2 of 20mg/kg was used to induce arrhythmias in 21 Wistar rats of either sex. Five of the rats that were not treated with piperazine following BaCl administration died within one minute from ventricular fibrillation. Among the 10 rats with BaCl2-induced dysrhythmia, treated with piperazine, five ...
VAGINAL BLEEDING AFTER USE OF SINGLE DOSE ORAL
... and gynecological conditions. In gastroenterologic use, misoprostol therapy indicated in patients who have duodenal or gastric ulcer due to use nonsteroidal anti-inflammatory drugs (NSAIDs). It acts upon gastric parietal cells, inhibiting the secretion of gastric acid. It is only indicated for use b ...
... and gynecological conditions. In gastroenterologic use, misoprostol therapy indicated in patients who have duodenal or gastric ulcer due to use nonsteroidal anti-inflammatory drugs (NSAIDs). It acts upon gastric parietal cells, inhibiting the secretion of gastric acid. It is only indicated for use b ...
HUMAN PHARMACOLOGY AYAHUASCA Director de la Tesi:
... areas of Colombia and Ecuador to the Río Negro in Brazil (Ott, 1993). While the term ayahuasca, which also designates the plant the beverage is made from, is used in Peru and some areas of Ecuador and Colombia, this psychotropic tea is also known by many other vernacular names. The term caapi is emp ...
... areas of Colombia and Ecuador to the Río Negro in Brazil (Ott, 1993). While the term ayahuasca, which also designates the plant the beverage is made from, is used in Peru and some areas of Ecuador and Colombia, this psychotropic tea is also known by many other vernacular names. The term caapi is emp ...
105 CMR - Secretary of the Commonwealth
... equivalent or identical with any of the substances referred to in 105 CMR 700.001(T)(1), but not including the isoquinoline alkaloids of opium; (3) Opium poppy and poppy straw; (4) Coca leaves and any salt, compound, derivative, or preparation of coca leaves, and any salt, compound, isomer, derivati ...
... equivalent or identical with any of the substances referred to in 105 CMR 700.001(T)(1), but not including the isoquinoline alkaloids of opium; (3) Opium poppy and poppy straw; (4) Coca leaves and any salt, compound, derivative, or preparation of coca leaves, and any salt, compound, isomer, derivati ...
Guideline on Inhalational medicinal products
... general principles described here should also be considered for products used in clinical trials. It is not expected that all described testing would be conducted on all clinical trial batches. However, extensive characterisation of the drug substance and drug product batches used in pivotal clinica ...
... general principles described here should also be considered for products used in clinical trials. It is not expected that all described testing would be conducted on all clinical trial batches. However, extensive characterisation of the drug substance and drug product batches used in pivotal clinica ...
GHB - CAP Members
... GHB and its analogues are abused for their euphoric and calming effects and because some people believe they build muscles and cause weight loss. GHB and its analogues are also misused for their ability to increase libido, suggestibility, passivity, and to cause amnesia (no memory of events while un ...
... GHB and its analogues are abused for their euphoric and calming effects and because some people believe they build muscles and cause weight loss. GHB and its analogues are also misused for their ability to increase libido, suggestibility, passivity, and to cause amnesia (no memory of events while un ...
quality evidence - American Pain Society
... are ‘‘guides’’ only and may not apply to all patients and all clinical situations. Variations in practice, which take into account the needs of the individual patient and the resources and limitations unique to the institution or type of practice, may warrant approaches, treatments and/or procedures ...
... are ‘‘guides’’ only and may not apply to all patients and all clinical situations. Variations in practice, which take into account the needs of the individual patient and the resources and limitations unique to the institution or type of practice, may warrant approaches, treatments and/or procedures ...
Learning Objectives - Florida Alcohol and Drug Abuse Association
... • 20.64% of our opioid dependent patients who were not in COR-12 discharged atypically. • Only 11.11% of our opioid dependent patients enrolled in COR-12 discharged atypically. • COR-12 participants were 46% less likely to discharge atypically. • 6 former opioid dependent patients deceased in 2013; ...
... • 20.64% of our opioid dependent patients who were not in COR-12 discharged atypically. • Only 11.11% of our opioid dependent patients enrolled in COR-12 discharged atypically. • COR-12 participants were 46% less likely to discharge atypically. • 6 former opioid dependent patients deceased in 2013; ...
... and the same protocol for allergen dose increments was used at both occasions. For each challenge, the starting allergen dose was selected as 0.5–1 log below the PD20FEV1 determined with the same protocol at the control session. The patients always returned to the clinic the morning after each treat ...
Fact sheets
... which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “are expected to”, “will”, “will continue”, “should”, “would be”, “seeks”, “pending” or “anticipates” or similar expressions, or by discussions of strategy, plans or intentions. Such ...
... which can be identified by the use of forward-looking terminology such as “estimates”, “believes”, “expects”, “may”, “are expected to”, “will”, “will continue”, “should”, “would be”, “seeks”, “pending” or “anticipates” or similar expressions, or by discussions of strategy, plans or intentions. Such ...
COMPARATIVE EVALUATION OF NATURAL AND SYNTHETIC SUPERDISINTEGRANT FOR PROMOTING NIMESULIDE DISSOLUTION FOR FAST DISSOLVING TECHNOLOGY
... and film formers. Apart from its use in finished medicines, newer uses have been found in the preparation of cosmetics, textiles, and paint paper. Mucilage of natural origin is preferred over synthetic and semisynthetic agent because they are cheaper, abundantl ...
... and film formers. Apart from its use in finished medicines, newer uses have been found in the preparation of cosmetics, textiles, and paint paper. Mucilage of natural origin is preferred over synthetic and semisynthetic agent because they are cheaper, abundantl ...
Prednisolone and hiccups Introduction
... Other causes include gastrointestinal disorders, thoracic disorders or cardiac disorders. Hiccups may also be drug-related. In rare cases, hiccups can be a manifestation of severe underlying disease (eg, malignancy, multiple sclerosis) [4]. Reports The Netherlands Pharmacovigilance Centre Lareb rece ...
... Other causes include gastrointestinal disorders, thoracic disorders or cardiac disorders. Hiccups may also be drug-related. In rare cases, hiccups can be a manifestation of severe underlying disease (eg, malignancy, multiple sclerosis) [4]. Reports The Netherlands Pharmacovigilance Centre Lareb rece ...