Clofibric acid
... benign and malignant liver tumors than in controls. There was an increase in benign Leydig cell tumors in male rats treated at 400 mg/kg/day or 2 times the maximum recommended human dose in one study. A comparative carcinogenicity study was also done in rats comparing three drugs in this class: feno ...
... benign and malignant liver tumors than in controls. There was an increase in benign Leydig cell tumors in male rats treated at 400 mg/kg/day or 2 times the maximum recommended human dose in one study. A comparative carcinogenicity study was also done in rats comparing three drugs in this class: feno ...
Toxic epidermal necrolysis: an update
... was first described by Lyell and now is recognized as TEN Lyell’s syndrome[4]. It had become clear that TEN was druginduced, and the drugs such as sulfonamides, pyrazolones, barbiturates, and antiepileptics were the most frequent triggers of TEN. SJS and TEN are considered to be two ends of a spectr ...
... was first described by Lyell and now is recognized as TEN Lyell’s syndrome[4]. It had become clear that TEN was druginduced, and the drugs such as sulfonamides, pyrazolones, barbiturates, and antiepileptics were the most frequent triggers of TEN. SJS and TEN are considered to be two ends of a spectr ...
Drug Trend Report
... • A generic for Prograf® was approved August 10, 2009, but was not launched/available until October 13, 2009. • Ranbaxy’s Valtrex (valacyclovir) generic received approval in January 2007, but did not launch until 2009. • The 2008 settlement agreement between AstraZeneca and Teva allowed Teva to c ...
... • A generic for Prograf® was approved August 10, 2009, but was not launched/available until October 13, 2009. • Ranbaxy’s Valtrex (valacyclovir) generic received approval in January 2007, but did not launch until 2009. • The 2008 settlement agreement between AstraZeneca and Teva allowed Teva to c ...
i p&l?, FNG”,, /
... are often, not known, and ascribing any observed side effects to phenylpropanolamine alone is ludicrous, although done by some authors. Of the 101 documents, 37 were review -in nature. Also, 34 were related to overdose, ingestion of combinations of drugs, or drug misuse. Thus, of the 101 reports, 71 ...
... are often, not known, and ascribing any observed side effects to phenylpropanolamine alone is ludicrous, although done by some authors. Of the 101 documents, 37 were review -in nature. Also, 34 were related to overdose, ingestion of combinations of drugs, or drug misuse. Thus, of the 101 reports, 71 ...
SSRIs for the treatment of Depression in children and
... be continued for at least 6 months after remission (defined as no symptoms and full functioning for at least 8 weeks); in other words, for 6 months after this 8 week period When a child or young person responds to treatment with citalopram or sertraline, medication should be continued for at least 6 ...
... be continued for at least 6 months after remission (defined as no symptoms and full functioning for at least 8 weeks); in other words, for 6 months after this 8 week period When a child or young person responds to treatment with citalopram or sertraline, medication should be continued for at least 6 ...
Michael Barry Michael Barry - Irish Pharmaceutical Healthcare
... (Losec Mups) and pravastatin (Lipostat) later. It is envisaged that 20 drugs will be identified as interchangable by May 2014. In setting the reference price the following criteria are considered: 1. The ability of suppliers to meet patient demand 2. Value for money afforded by the relevant listed i ...
... (Losec Mups) and pravastatin (Lipostat) later. It is envisaged that 20 drugs will be identified as interchangable by May 2014. In setting the reference price the following criteria are considered: 1. The ability of suppliers to meet patient demand 2. Value for money afforded by the relevant listed i ...
Document
... In 2006, 35 per cent of a sample of Australian PWID reported that pharmaceutical opioids were the last drug they had injected24; most identified their drugs as non-opioid substitution therapy (OST) opioids (18 per cent morphine) rather than OST opioids (8 per cent methadone, 6 per cent buprenorphine ...
... In 2006, 35 per cent of a sample of Australian PWID reported that pharmaceutical opioids were the last drug they had injected24; most identified their drugs as non-opioid substitution therapy (OST) opioids (18 per cent morphine) rather than OST opioids (8 per cent methadone, 6 per cent buprenorphine ...
Sedation and antipsychotics
... Allow diagnostic assessment to proceed Allow transport to an appropriate treatment setting ...
... Allow diagnostic assessment to proceed Allow transport to an appropriate treatment setting ...
Frequently Asked Questions on Use of
... suitable for those on tamoxifen therapy.52,54,55 The tricyclic antidepressants are metabolised by several cytochrome enzymes and drugdrug interactions are common; however, they are regarded as having weak CYP2D6 inhibitory activity.3,54 For patients who do not respond to other antidepressants, fluox ...
... suitable for those on tamoxifen therapy.52,54,55 The tricyclic antidepressants are metabolised by several cytochrome enzymes and drugdrug interactions are common; however, they are regarded as having weak CYP2D6 inhibitory activity.3,54 For patients who do not respond to other antidepressants, fluox ...
osphena
... • Osphena is an estrogen agonist/antagonist indicated for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause • Osphena selectively binds to estrogen receptors, inducing changes to the vaginal epithelium and decreasing vaginal pH • There is an i ...
... • Osphena is an estrogen agonist/antagonist indicated for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause • Osphena selectively binds to estrogen receptors, inducing changes to the vaginal epithelium and decreasing vaginal pH • There is an i ...
Behavior Products and Medications
... which dampens anxiety responses by stopping neural transmission and the excessive firing associated with anxiety. It can also increase serotonin and dopamine levels as well making it well suited to help in a variety of different situational and global anxiety disorders. Solliquin (Nutramax Labs)- So ...
... which dampens anxiety responses by stopping neural transmission and the excessive firing associated with anxiety. It can also increase serotonin and dopamine levels as well making it well suited to help in a variety of different situational and global anxiety disorders. Solliquin (Nutramax Labs)- So ...
Opiates: Good or Bad?
... of the drugs creates false sense of euphoria. It is believed that opiates activate the dopaminergic systems, which leads to an opiate high, although it is not completely understood [4]. Due to the highly addictive nature of opiates, users are likely to solicit in illegal activities or become violent ...
... of the drugs creates false sense of euphoria. It is believed that opiates activate the dopaminergic systems, which leads to an opiate high, although it is not completely understood [4]. Due to the highly addictive nature of opiates, users are likely to solicit in illegal activities or become violent ...
Control of intravenous medication wastage at a teaching hospital in
... problematic issue in the health care system. How to save medication wastages need some techniques and methodologies to be adapted.1 As shown in the literature, the total national costs due to medication wastage would not be less than 1$ billion per year in the United States.2 Drug wastage has been r ...
... problematic issue in the health care system. How to save medication wastages need some techniques and methodologies to be adapted.1 As shown in the literature, the total national costs due to medication wastage would not be less than 1$ billion per year in the United States.2 Drug wastage has been r ...
Half the 25,673 patients in the study were given Merck`s Tredaptive
... agent alone, 10 of the 14 monotherapy trials with DHA showed increases in LDL cholesterol ranging from 5.4% to 16.0% vs control, while none of the EPA trials showed any increase. The changes in LDL-cholesterol levels significantly correlated with baseline triglyceride levels for DHA-treated patients ...
... agent alone, 10 of the 14 monotherapy trials with DHA showed increases in LDL cholesterol ranging from 5.4% to 16.0% vs control, while none of the EPA trials showed any increase. The changes in LDL-cholesterol levels significantly correlated with baseline triglyceride levels for DHA-treated patients ...
DRUGS INFLUENCING COGNITIVE FUNCTION
... children with epilepsy have more learning difficulties than age matched controls (2, 3). Anti-epileptic drugs are useful in controlling the frequency and duration of seizures. These drugs can also be the source of side effects including cognitive impairment. Since 1975, greater attention has been gi ...
... children with epilepsy have more learning difficulties than age matched controls (2, 3). Anti-epileptic drugs are useful in controlling the frequency and duration of seizures. These drugs can also be the source of side effects including cognitive impairment. Since 1975, greater attention has been gi ...
this publication - G
... the treatment of diseases such as cancer, requires long-term therapy [5-7]. Using of nanosystems for drug delivery in cancer therapy allows to achieve significantly better effects than by using free drugs [3,8-10]. One of the anti-cancer drugs is «Arglabin» obtained by Kazakhstan scientists from the ...
... the treatment of diseases such as cancer, requires long-term therapy [5-7]. Using of nanosystems for drug delivery in cancer therapy allows to achieve significantly better effects than by using free drugs [3,8-10]. One of the anti-cancer drugs is «Arglabin» obtained by Kazakhstan scientists from the ...
Modern Methods in Drug Discovery
... Function of the blood-brain barrier in silico prediction of the blood-brain barrier permeability in the course of pre-clinical development is particularly important, since • only substances that shall act on the central nervous system (CNS), should pass the blood-brain barrier effectively. • BBB-sc ...
... Function of the blood-brain barrier in silico prediction of the blood-brain barrier permeability in the course of pre-clinical development is particularly important, since • only substances that shall act on the central nervous system (CNS), should pass the blood-brain barrier effectively. • BBB-sc ...
Why Olanzapine Beats Risperidone, Risperidone Beats Exploratory Analysis of Head-to-Head Comparison
... the other hand, side effects might be more likely to appear with fast dose escalation. The attempt to escape the escalation problem by using a fixed-dose regimen raises other problems. Studies with fixed-dose regimens lack naturalistic plausibility because the unrealistic limits imposed do not refle ...
... the other hand, side effects might be more likely to appear with fast dose escalation. The attempt to escape the escalation problem by using a fixed-dose regimen raises other problems. Studies with fixed-dose regimens lack naturalistic plausibility because the unrealistic limits imposed do not refle ...
APO-go® PEN
... Issue Date: September 2010 Approved by: GPMTC Page 1 of 5 Review Date: September 2012 ...
... Issue Date: September 2010 Approved by: GPMTC Page 1 of 5 Review Date: September 2012 ...
QUANTITATIVE ANALYSIS OF DOSE
... mechanisms (sequential or ping-pong) of the reaction under consideration. The simplicity of the above equations (in which all specific kinetic constants, substrate concentration factors, and Vmax have been cancelled out during derivation) suggests their general applicability (5, 6). This is in contr ...
... mechanisms (sequential or ping-pong) of the reaction under consideration. The simplicity of the above equations (in which all specific kinetic constants, substrate concentration factors, and Vmax have been cancelled out during derivation) suggests their general applicability (5, 6). This is in contr ...
Inhibition by Etomidate of Steroidogenesis by Isolated Bovine
... dopamine agonist which suppresses Prl secretion is known to be effective in some women with cyclical oedema and it is possible that the hypothalamic disturbance includes a reduction in dopaminergic activity. Pergolide mesylate is a new, potent and long acting dopamine agocist and is a potentially ef ...
... dopamine agonist which suppresses Prl secretion is known to be effective in some women with cyclical oedema and it is possible that the hypothalamic disturbance includes a reduction in dopaminergic activity. Pergolide mesylate is a new, potent and long acting dopamine agocist and is a potentially ef ...
Meeting Report: Technical Definitions of Shortages and Stockouts of
... shortage or stockout. The example discussed was the definition of “acceptable shelf life”, which is commonly used as an acceptance criteria in procurement, i.e., if the medicine has less than a certain percentage of its original shelf life upon departure from the manufacturing facility (or on arriva ...
... shortage or stockout. The example discussed was the definition of “acceptable shelf life”, which is commonly used as an acceptance criteria in procurement, i.e., if the medicine has less than a certain percentage of its original shelf life upon departure from the manufacturing facility (or on arriva ...