SEROQUEL (quetiapine fumarate) TABLETS HIGHLIGHTS OF PRESCRIBING INFORMATION
... SEROQUEL is indicated as monotherapy for the acute treatment of depressive episodes associated with bipolar disorder. Efficacy was established in two 8-week monotherapy trials in adult patients with bipolar I and bipolar II disorder [see Clinical Studies (14.2)]. SEROQUEL is indicated for the mainte ...
... SEROQUEL is indicated as monotherapy for the acute treatment of depressive episodes associated with bipolar disorder. Efficacy was established in two 8-week monotherapy trials in adult patients with bipolar I and bipolar II disorder [see Clinical Studies (14.2)]. SEROQUEL is indicated for the mainte ...
Seroquel - PI
... SEROQUEL is indicated as monotherapy for the acute treatment of depressive episodes associated with bipolar disorder. Efficacy was established in two 8-week monotherapy trials in adult patients with bipolar I and bipolar II disorder [see Clinical Studies (14.2)]. SEROQUEL is indicated for the mainte ...
... SEROQUEL is indicated as monotherapy for the acute treatment of depressive episodes associated with bipolar disorder. Efficacy was established in two 8-week monotherapy trials in adult patients with bipolar I and bipolar II disorder [see Clinical Studies (14.2)]. SEROQUEL is indicated for the mainte ...
Noxafil - Merck.com
... Equilibrate the refrigerated vial of Noxafil (posaconazole) injection to room temperature. To prepare the required dose, aseptically transfer one vial (16.7 mL) of Noxafil injection (containing 300 mg of posaconazole in solution) to an intravenous bag (or bottle) of a compatible admixture diluent (a ...
... Equilibrate the refrigerated vial of Noxafil (posaconazole) injection to room temperature. To prepare the required dose, aseptically transfer one vial (16.7 mL) of Noxafil injection (containing 300 mg of posaconazole in solution) to an intravenous bag (or bottle) of a compatible admixture diluent (a ...
PRODUCT MONOGRAPH UNIPHYL Theophylline Sustained
... The variability in serum levels is primarily due to differences in the rate of metabolism. Therefore, it is advisable to individualize the dosage regimen. Ideally, all patients should have serum theophylline levels measured which would enable doses and dosing regimens to be tailored for each patient ...
... The variability in serum levels is primarily due to differences in the rate of metabolism. Therefore, it is advisable to individualize the dosage regimen. Ideally, all patients should have serum theophylline levels measured which would enable doses and dosing regimens to be tailored for each patient ...
PRODUCT MONOGRAPH Cipralex Escitalopram Oxalate
... monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase in the early stages of recovery. Therefore, high-risk patients should be closely supervised throughout therapy with consideration to the possible need for hospitalization. In order to min ...
... monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase in the early stages of recovery. Therefore, high-risk patients should be closely supervised throughout therapy with consideration to the possible need for hospitalization. In order to min ...
STALEVO (carbidopa, levodopa and entacapone)
... Postmarketing reports suggest that patients treated with anti-Parkinson medications can experience intense urges to gamble, increased sexual urges, intense urges to spend money uncontrollably, and other intense urges. Patients may be unable to control these urges while taking one or more of the medi ...
... Postmarketing reports suggest that patients treated with anti-Parkinson medications can experience intense urges to gamble, increased sexual urges, intense urges to spend money uncontrollably, and other intense urges. Patients may be unable to control these urges while taking one or more of the medi ...
Activity and Enzyme Kinetics of Human UDP
... The main goal of this thesis was to investigate the activity and enzyme kinetics of UGTs, as well as the in vitro assay conditions needed to accurately determine the enzyme kinetic parameters. Particular attention focused on the glucuronidation of psilocin, the enhancement of UGT activity by the inc ...
... The main goal of this thesis was to investigate the activity and enzyme kinetics of UGTs, as well as the in vitro assay conditions needed to accurately determine the enzyme kinetic parameters. Particular attention focused on the glucuronidation of psilocin, the enhancement of UGT activity by the inc ...
Comparison of the Effects of Pilocarpine Solution and Tablet on
... for xerostomic patients. Because of unwanted side effects following its systemic administration, topical pilocarpine has been paid attention as an alternative. This study aimed to investigate effects of pilocarpine solution as mouthwash on salivary flow and adverse effects compared to systemic admin ...
... for xerostomic patients. Because of unwanted side effects following its systemic administration, topical pilocarpine has been paid attention as an alternative. This study aimed to investigate effects of pilocarpine solution as mouthwash on salivary flow and adverse effects compared to systemic admin ...
see Warnings and - Boehringer Ingelheim
... although there were patients who first developed a serum sodium <125 mmol/L more than one year after initiation of therapy. Most patients who developed hyponatremia were asymptomatic but patients in the clinical trials were frequently monitored and some had their oxcarbazepine dose reduced, disconti ...
... although there were patients who first developed a serum sodium <125 mmol/L more than one year after initiation of therapy. Most patients who developed hyponatremia were asymptomatic but patients in the clinical trials were frequently monitored and some had their oxcarbazepine dose reduced, disconti ...
ICH Q3D Guideline (Elemental Impurities)
... establishment of a Permitted Daily Exposure (PDE) for each element of toxicological concern, and development of controls designed to limit the inclusion of elemental impurities in drug products to levels at or below the PDE. It is not expected that an applicant tightens the limits based on process c ...
... establishment of a Permitted Daily Exposure (PDE) for each element of toxicological concern, and development of controls designed to limit the inclusion of elemental impurities in drug products to levels at or below the PDE. It is not expected that an applicant tightens the limits based on process c ...
Plavix - Sanofi Canada
... ticlopidine, prasugrel) since cross-reactivity among thienopyridines has been reported (see ADVERSE REACTIONS). Thienopyridines may cause mild to severe allergic reactions such as rash, angioedema, or haematological reactions such as thrombocytopaenia and neutropaenia. Patients who had developed a p ...
... ticlopidine, prasugrel) since cross-reactivity among thienopyridines has been reported (see ADVERSE REACTIONS). Thienopyridines may cause mild to severe allergic reactions such as rash, angioedema, or haematological reactions such as thrombocytopaenia and neutropaenia. Patients who had developed a p ...
19529550 Albuterol PI
... Preclinical: Intravenous studies in rats with albuterol sulfate have demonstrated that albuterol crosses the blood-brain barrier and reaches brain concentrations that are amounting to approximately 5.0% of the plasma concentrations. In structures outside the bloodbrain barrier (pineal and pituitary ...
... Preclinical: Intravenous studies in rats with albuterol sulfate have demonstrated that albuterol crosses the blood-brain barrier and reaches brain concentrations that are amounting to approximately 5.0% of the plasma concentrations. In structures outside the bloodbrain barrier (pineal and pituitary ...
Clinical Manual Part 2 Drug Infusion Guidelines
... intravenous rate controlling device such as an IVAC infusion pump. Although greater fluid volumes are necessary, there is a greater margin of safety in controlling rates, especially during transport and handover. ...
... intravenous rate controlling device such as an IVAC infusion pump. Although greater fluid volumes are necessary, there is a greater margin of safety in controlling rates, especially during transport and handover. ...
Martindale: The Complete Drug Reference
... cefuroxime axetil and cefuroxime sodium are expressed in terms of the equivalent amount of cefuroxime; 1.20 g of cefuroxime axetil and 1.05 g of cefuroxime sodium are each equivalent to about 1 g of cefuroxime. The usual oral dose is 250 mg twice daily; for uncomplicated urinary-tract infections 125 ...
... cefuroxime axetil and cefuroxime sodium are expressed in terms of the equivalent amount of cefuroxime; 1.20 g of cefuroxime axetil and 1.05 g of cefuroxime sodium are each equivalent to about 1 g of cefuroxime. The usual oral dose is 250 mg twice daily; for uncomplicated urinary-tract infections 125 ...
Nicotine increases sucrose selfadministration and seeking in rats
... Correspondence to: Jeffrey W. Grimm, Department of Psychology and Program in Behavioral Neuroscience, Western Washington University, 516 High Street, Bellingham, WA 98225-9172, USA. E-mail: [email protected] ...
... Correspondence to: Jeffrey W. Grimm, Department of Psychology and Program in Behavioral Neuroscience, Western Washington University, 516 High Street, Bellingham, WA 98225-9172, USA. E-mail: [email protected] ...
ACPA Resource Guide 2013 Edition Chronic Pain Medication & Treatment
... This Guide is not meant to serve as medical advice for your condition or regarding your treatment needs. Remember that the best source of information about your health and treatment needs is from an open dialogue with your health care professional (in this document the word “health care professional ...
... This Guide is not meant to serve as medical advice for your condition or regarding your treatment needs. Remember that the best source of information about your health and treatment needs is from an open dialogue with your health care professional (in this document the word “health care professional ...
HYPOTHESES 59
... the central nervous system. In addition to the action of DMT on serotonin receptors, it has also been suggested that ayahuasca's psychoactive effects may also be partly due to a general increase of catecholamines and serotonin (Callaway et al. 1999). This increase would be due to both the inhibited ...
... the central nervous system. In addition to the action of DMT on serotonin receptors, it has also been suggested that ayahuasca's psychoactive effects may also be partly due to a general increase of catecholamines and serotonin (Callaway et al. 1999). This increase would be due to both the inhibited ...
Drug-induced psychomimetic effects as a model for psychosis
... and reserpine, let to the introduction of many more antipsychotic drugs with a similar mechanism of action, which are now referred to as typical antipsychotics (e.g. haloperidol, flupentixol, droperidol). In 1963, Carlsson and Lidqvist discovered that dopamine acts as a neurotransmitter (Carlsson a ...
... and reserpine, let to the introduction of many more antipsychotic drugs with a similar mechanism of action, which are now referred to as typical antipsychotics (e.g. haloperidol, flupentixol, droperidol). In 1963, Carlsson and Lidqvist discovered that dopamine acts as a neurotransmitter (Carlsson a ...
Seroquel - PI
... SEROQUEL is indicated for the acute treatment of manic episodes associated with bipolar I disorder, both as monotherapy and as an adjunct to lithium or divalproex. Efficacy was established in two 12-week monotherapy trials in adults, in one 3-week adjunctive trial in adults, and in one 3-week monoth ...
... SEROQUEL is indicated for the acute treatment of manic episodes associated with bipolar I disorder, both as monotherapy and as an adjunct to lithium or divalproex. Efficacy was established in two 12-week monotherapy trials in adults, in one 3-week adjunctive trial in adults, and in one 3-week monoth ...
Xtram
... opioid-dependent monkeys. Because of the difficulty in assessing dependence in patients who have previously received substantial amounts of opioid medications, caution should be used in the administration of Tramadol to such patients. In patients with a tendency for drug abuse or dependence, treatme ...
... opioid-dependent monkeys. Because of the difficulty in assessing dependence in patients who have previously received substantial amounts of opioid medications, caution should be used in the administration of Tramadol to such patients. In patients with a tendency for drug abuse or dependence, treatme ...
Chapter X
... More MDI Use Instructions • For a second puff, wait about 1 minute, then return to Step 1. • If another inhaler is prescribed, wait 5 minutes before use. • Clean mouthpiece after every use • Rinse mouthpiece if corticosteroid is used • Treatment should be reviewed every 3 to 6 months © Paradigm Pub ...
... More MDI Use Instructions • For a second puff, wait about 1 minute, then return to Step 1. • If another inhaler is prescribed, wait 5 minutes before use. • Clean mouthpiece after every use • Rinse mouthpiece if corticosteroid is used • Treatment should be reviewed every 3 to 6 months © Paradigm Pub ...
Assessment of zopiclone - World Health Organization
... containing different subunits. Receptors containing gamma2 appear to have a vital role in maintaining appropriate central inhibition; beta3-containing receptors may also be important determinants of excitability in certain brain regions, whereas a clear role for alpha5-, alpha6- and gamma3-containin ...
... containing different subunits. Receptors containing gamma2 appear to have a vital role in maintaining appropriate central inhibition; beta3-containing receptors may also be important determinants of excitability in certain brain regions, whereas a clear role for alpha5-, alpha6- and gamma3-containin ...
kopia+_Eli_PR5`2006.vp:CorelVentura 7.0
... The effect of vinpocetine or piracetam on thermal and visceral pain was studied in mice. In the hot plate test, vinpocetine (0.9 and 1.8 mg/kg), but not piracetam, produced a reduction in nociceptive response. Vinpocetine (0.45–1.8 mg/kg, ip) or piracetam (75–300 mg/kg, ip) caused dose-dependent inh ...
... The effect of vinpocetine or piracetam on thermal and visceral pain was studied in mice. In the hot plate test, vinpocetine (0.9 and 1.8 mg/kg), but not piracetam, produced a reduction in nociceptive response. Vinpocetine (0.45–1.8 mg/kg, ip) or piracetam (75–300 mg/kg, ip) caused dose-dependent inh ...
HYDROMORPHONE HYDROCHLORIDE TABLETS USP 2 mg, 4
... been studied. Further increase in Cmax and AUC of hydromorphone in this group is expected. As such, starting dose should be even more conservative. Use of oral liquid is recommended to adjust the dose (see DOSAGE AND ADMINISTRATION). Renal Impairment – After oral administration of hydromorphone at a ...
... been studied. Further increase in Cmax and AUC of hydromorphone in this group is expected. As such, starting dose should be even more conservative. Use of oral liquid is recommended to adjust the dose (see DOSAGE AND ADMINISTRATION). Renal Impairment – After oral administration of hydromorphone at a ...