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Full Text - AIMS Press
Full Text - AIMS Press

... organs like brain, liver, or kidney is less vascularized which is the principal reason why drugs penetrate ...
Epinephrine and local anesthesia revisited
Epinephrine and local anesthesia revisited

... the vasoconstrictors NE and levonordefrin). Nevertheless, they noted that the interaction between vasoconstrictors and TCAs (without distinguishing between NE and epinephrine) deserves special comment because it has ‘‘firm experimental verification,’’ to quote Boakes et al43 and Svedmyr.44 Furthermo ...
Changes in antacid use over a 9-year period in a general
Changes in antacid use over a 9-year period in a general

... still commonly used self-prescribed drugs1,2. However, their importance has diminished since the development of histamine-2-receptor antagonists and more recently proton pump inhibitors. Based on the drug wholesale statistics in Norway, the sale of antacids decreased from 7.6 DDD/1000 inhabitants/da ...
Pharmacy - Beirut Arab University
Pharmacy - Beirut Arab University

... Fundamentals of medicinal chemistry and an introduction to the properties of physiochemical drugs relative to their biological effects. Chemical and biochemical aspects of certain drug categories including: Antibiotics and anti - infective agents (antibacterial sulfonamides, quinolones, antitubercul ...
Medicines Management Programme Preferred Drugs Calcium
Medicines Management Programme Preferred Drugs Calcium

... nifedipine slow-release (SR) or gastrointestinal therapeutic system (GITS).15,16 The second (subclass B) is comprised of chemical entities which have less negative effect on myocardial contractility and heart rate and reduced effect on atrioventricular conduction (e.g. nilvadipine).18 In clinical tr ...
Bulletin #115
Bulletin #115

... fails to respond or if there is loss of response to the first agent. Requests for coverage for this indication must be made by the rheumatologist. A second application would also be required after 12 weeks to assess and would need to show an improvement to the patient’s condition on either of these ...
Psychostimulants and Cognition: A Continuum of Behavioral and
Psychostimulants and Cognition: A Continuum of Behavioral and

... khat is sometimes given to school-age children by parents who believe that it improves academic performance (Al-Motarreb et al., 2002). In the United States and other Western cultures, amphetamine, methylphenidate, and other closely related drugs are successfully used in the treatment of a variety o ...
Influence of posture on pharmacokinetics
Influence of posture on pharmacokinetics

... standing vs. supine position) may substantially affect the metabolism of orally administered drugs, especially of those with a high/saturable first-pass metabolism. For highly protein-bound drugs (e.g. phenytoin, imipramine), the total plasma concentration has been found to be approximately 10% high ...
Neurobiological substrates for the dark side of compulsivity in
Neurobiological substrates for the dark side of compulsivity in

... 1.1. Motivation, withdrawal, and opponent process Motivation is a state that can be defined as a ‘‘tendency of the whole animal to produce organized activity’’ (Hebb, 1972), and such motivational states are not constant but rather vary over time. Early work by Wikler stressed the role of changes in d ...
ZYBAN (bupropion hydrochloride) Sustained-Release
ZYBAN (bupropion hydrochloride) Sustained-Release

... intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of hypertensive reactions in a particular patient, ZYBAN should be stopped promptly, and linezolid or intravenous methylene blue can ...
Mephedrone: use, subjective effects and health risks
Mephedrone: use, subjective effects and health risks

... discordant results for the presence of cocaine in samples 2, 5, and 11‐13 where there was  reported use may reflect the low purity of cocaine presently variable in the UK (the average  purity  of  street  level  cocaine  has  fallen  from  51.2%  in  2003  to  20.3%  in  2009[12]).  We  also  consid ...
Secundum Artem
Secundum Artem

... Azathioprine is a purine antagonist antimetabolite used mainly for its immunosuppresive activity. It occurs as a pale yellow, odorless powder that is insoluble in water and very slightly soluble in alcohol. It is available as a sodium salt for injection that, when constituted as directed, the soluti ...
PRODUCT INFORMATION
PRODUCT INFORMATION

... Check the following before use: In long-term therapy, periodic laboratory evaluation of organ systems, including haemopoietic, renal and hepatic studies should be performed. The use of the drugs of the tetracycline class, including doxycycline, during tooth development (latter half of pregnancy, inf ...
O A
O A

... Figure (2) shows the UV absorption spectra of leflunomide and its alkaline degradate. As figure (2) shows, the large overlap of the spectral bands of the two compounds prevents the selective determination of leflunomide in a mixture of the intact drug and its degradate from their zero order spectra. ...
BUPRENORPHINE THERAPIES FOR THE TREATMENT OF OPIOID
BUPRENORPHINE THERAPIES FOR THE TREATMENT OF OPIOID

... Evidence from the many studies on buprenorphine in the treatment of opioid dependence has been increasingly debated amongst physicians and policy-makers and the introduction of a new medication in the context of existing therapeutic approaches, in this case predominantly methadone, naturally leads t ...
Formatted for submission - NCI Consent Form Template for Adult
Formatted for submission - NCI Consent Form Template for Adult

... about you. Someone might be able to trace this information back to you. The researchers believe the chance that someone will identify you is very small, but the risk may change in the future as people come up with new ways of tracing information. In some cases, this information could be used to make ...
November 2016 PBAC Meeting Agenda
November 2016 PBAC Meeting Agenda

... Listing requested by Sponsor / Purpose of Submission (Includes type of listing requested (unrestricted, restricted benefit, authority required) and restriction wording. If restriction is lengthy it may be paraphrased.) To request a Section 100 (Efficient Funding of Chemotherapy) Authority Required ( ...
Drug * Herb Interactions
Drug * Herb Interactions

...  Statements may be included on the label that give the manufacturers description of the role of the D/S  Must be accompanied by disclaimer  “This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease” UC Irvine - Reynolds Grant ...
PHARMACEUTICAL BENEFITS ADVISORY COMMITTEE (PBAC
PHARMACEUTICAL BENEFITS ADVISORY COMMITTEE (PBAC

... Listing requested by Sponsor / Purpose of Submission (Includes type of listing requested (unrestricted, restricted benefit, authority required) and restriction wording. If restriction is lengthy it may be paraphrased.) To request a Section 100 (Efficient Funding of Chemotherapy) Authority Required ( ...
Cancer Consent Template and Tutorial
Cancer Consent Template and Tutorial

... about you. Someone might be able to trace this information back to you. The researchers believe the chance that someone will identify you is very small, but the risk may change in the future as people come up with new ways of tracing information. In some cases, this information could be used to make ...
GHB
GHB

... Respiratory Depression Coma - Victims report knowing what is going on, but unable to move ...
Tasers - Paramedic Systems of Wisconsin
Tasers - Paramedic Systems of Wisconsin

... The Usual Suspects  #1 Cause: Stimulant Drug Abuse ...
Clinical Implications of Dihydropyrimidine
Clinical Implications of Dihydropyrimidine

... Clinical Consequences of Modulation of DPD Activity The importance of DPD to the clinical pharmacology of 5-FU has been further established by several recent observations (Table 1) that demonstrate that DPD can account for much of the variability that has been noted in clinical studies with 5-FU. Th ...
Anti-Rheumatic Medications During Pregnancy and Lactation (Part 2) Topical Medical Issues
Anti-Rheumatic Medications During Pregnancy and Lactation (Part 2) Topical Medical Issues

... maternal tissues and crosses the placenta to the fetus.1 Maternal ingestion of MTX prior to pregnancy (three months prior in the rheumatic diseases, but up to six to seven months prior in treatment of cancers) and during pregnancy has significant potential to cause spontaneous abortions, and is embr ...
SPECTROPHOTOMETRIC DETERMINATION OF OXCARBAZEPINE IN PHARMACEUTICAL  FORMULATIONS  Research Article  M. A. SATHISH AND G. NAGENDRAPPA*
SPECTROPHOTOMETRIC DETERMINATION OF OXCARBAZEPINE IN PHARMACEUTICAL  FORMULATIONS  Research Article  M. A. SATHISH AND G. NAGENDRAPPA*

... FORMULATIONS  ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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