Misoprostol in obstetrics and gynecology
... Misoprostol is an analogue of prostaglandin E1 (PG E1) which was registered in many countries during the second half of the 1980s under the proprietary name Cytotec (Pharmacia), for the treatment of peptic ulcers, particularly those caused by non-steroidal anti-inflammatory drugs [5– 7]. Its use for ...
... Misoprostol is an analogue of prostaglandin E1 (PG E1) which was registered in many countries during the second half of the 1980s under the proprietary name Cytotec (Pharmacia), for the treatment of peptic ulcers, particularly those caused by non-steroidal anti-inflammatory drugs [5– 7]. Its use for ...
Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform
... opioids (Tortorici et al., 2007). The magnitude of altered activity of specific P450 isoforms in CA with changes in body temperature is poorly understood. In addition, during hypothermia after CA, the alterations in normal drug metabolism can be quite complex because of suppressed effects from heart ...
... opioids (Tortorici et al., 2007). The magnitude of altered activity of specific P450 isoforms in CA with changes in body temperature is poorly understood. In addition, during hypothermia after CA, the alterations in normal drug metabolism can be quite complex because of suppressed effects from heart ...
Pethidine FAQs
... metabolism of pethidine, and thus increasing production of norpethidine. Data are derived from one pharmacokinetic study in which 4 normal subjects received pethidine (50mg IV and 100mg orally) before and after phenytoin 1g followed by 300mg daily for 9 days20. The area under the blood concentration ...
... metabolism of pethidine, and thus increasing production of norpethidine. Data are derived from one pharmacokinetic study in which 4 normal subjects received pethidine (50mg IV and 100mg orally) before and after phenytoin 1g followed by 300mg daily for 9 days20. The area under the blood concentration ...
HIGHLIGHTS OF PRESCRIBING INFORMATION -----------------DOSAGE FORMS AND STRENGTHS------
... diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. ...
... diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. ...
The Dopamine Transporter and Cocaine Medication Development
... clear and clinically relevant characterization of medication effectiveness in subjects with a documented history of drug use under well controlled laboratory conditions. The problems of polydrug use and lifestyle characteristics that are major concerns in human studies are eliminated. Research effor ...
... clear and clinically relevant characterization of medication effectiveness in subjects with a documented history of drug use under well controlled laboratory conditions. The problems of polydrug use and lifestyle characteristics that are major concerns in human studies are eliminated. Research effor ...
prescribing information
... pallor; nausea and vomiting; headache; and/or respiratory difficulties. These symptoms occur in some persons receiving therapeutic doses of epinephrine, but are more likely to occur in patients with hypertension or hyperthyroidism. Arrhythmias, including fatal ventricular fibrillation, have been rep ...
... pallor; nausea and vomiting; headache; and/or respiratory difficulties. These symptoms occur in some persons receiving therapeutic doses of epinephrine, but are more likely to occur in patients with hypertension or hyperthyroidism. Arrhythmias, including fatal ventricular fibrillation, have been rep ...
Marijuana Information marijuana
... from the director: By the time they graduate from high school, about 42 percent of teens will have tried marijuana. Although current use among U.S. teens has dropped dramatically in the past decade (to a prevalence of about 14 percent in 2009), this decline has stalled during the past several years. ...
... from the director: By the time they graduate from high school, about 42 percent of teens will have tried marijuana. Although current use among U.S. teens has dropped dramatically in the past decade (to a prevalence of about 14 percent in 2009), this decline has stalled during the past several years. ...
FORMULATION DEVELOPMENT, CHARACTERIZATION & ESTIMATION OF ACID
... consumed, was found to be in the range of 4.20 to 4.44 for different batches (Table 4). Overall the prepared tablet batches were of good quality with respect to hardness, friability, weight variation, thickness, disintegration time and acid neutralising capacity. Table 4: Acid neutralising capacity, ...
... consumed, was found to be in the range of 4.20 to 4.44 for different batches (Table 4). Overall the prepared tablet batches were of good quality with respect to hardness, friability, weight variation, thickness, disintegration time and acid neutralising capacity. Table 4: Acid neutralising capacity, ...
Liposomes in drug delivery
... Several methods have been developed for the preparation of large, unilamellar vesicles (LUV), including solvent (ether or ethanol) injection, detergent dialysis, calcium induced fusion, and reverse-phase evaporation (REV) techniques. SUV can be prepared from MLV or LUV by sonication (using probe son ...
... Several methods have been developed for the preparation of large, unilamellar vesicles (LUV), including solvent (ether or ethanol) injection, detergent dialysis, calcium induced fusion, and reverse-phase evaporation (REV) techniques. SUV can be prepared from MLV or LUV by sonication (using probe son ...
World Federation of Societies of Biological Psychiatry (WFSBP)
... Objectives. To define a practice guideline for biological treatment of dementia and to make transparent the development of the guideline connecting the original data with the resulting recommendations. Methods. This guideline includes pharmacologic treatment considerations for patients with Alzheime ...
... Objectives. To define a practice guideline for biological treatment of dementia and to make transparent the development of the guideline connecting the original data with the resulting recommendations. Methods. This guideline includes pharmacologic treatment considerations for patients with Alzheime ...
Thyroid and Parathyroid Agents
... endocrine imbalance. What’s more, they also did not lose weight—and in the long run may actually have gained weight as the body’s compensatory mechanisms tried to deal with the imbalances. Today, thyroid hormone is no longer considered a good choice for treating obesity. Other drugs have come and go ...
... endocrine imbalance. What’s more, they also did not lose weight—and in the long run may actually have gained weight as the body’s compensatory mechanisms tried to deal with the imbalances. Today, thyroid hormone is no longer considered a good choice for treating obesity. Other drugs have come and go ...
PRESCRIBING INFORMATION Entex LA Pseudoephedrine
... ingested is considered dangerous or excessive, induce vomiting with ipecac syrup unless the patient is convulsing, comatose, or has lost the gag reflex, in which case perform gastric lavage using a large bore tube. If indicated, follow with activated charcoal and saline cathartic. Since the effects ...
... ingested is considered dangerous or excessive, induce vomiting with ipecac syrup unless the patient is convulsing, comatose, or has lost the gag reflex, in which case perform gastric lavage using a large bore tube. If indicated, follow with activated charcoal and saline cathartic. Since the effects ...
Guidance for Performing a Medication Error Potential Risk Assessment
... As well as chemical stability data, evaluation of aseptic product shelf lives must involve evaluation of physical characteristics, and microbiological stability validation (container integrity). The latter is unit and process specific and is outside the scope of this protocol ...
... As well as chemical stability data, evaluation of aseptic product shelf lives must involve evaluation of physical characteristics, and microbiological stability validation (container integrity). The latter is unit and process specific and is outside the scope of this protocol ...
Filling two-piece hard gelatin capsules with liquids
... have attracted substantial interest in the pharmaceutical industry over the last decade. Today’s challenges in product development due to the poor aqueous solubility and high potency of the new molecular entities are being addressed by several development groups that are focused on liquid or semi-so ...
... have attracted substantial interest in the pharmaceutical industry over the last decade. Today’s challenges in product development due to the poor aqueous solubility and high potency of the new molecular entities are being addressed by several development groups that are focused on liquid or semi-so ...
Potential Drug Interactions - edoc
... Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events. In the last 40 years an enormous amount of data on drug interactions has been published. But, although potential dru ...
... Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events. In the last 40 years an enormous amount of data on drug interactions has been published. But, although potential dru ...
Lecture_16.Alicyclic_antibiotics
... U.A. – the minimum molar amount of the antibiotic, which inhibits the development of a test microorganism in a certain volume of the medium. The number of grams of active ingredient in U.A. is variety for different antibiotics! The average value of the activity, which was found by a biological meth ...
... U.A. – the minimum molar amount of the antibiotic, which inhibits the development of a test microorganism in a certain volume of the medium. The number of grams of active ingredient in U.A. is variety for different antibiotics! The average value of the activity, which was found by a biological meth ...
QA135_4chondroitin_DI
... danaparoid, an anticoagulant that works by inhibiting activated factor X, it might have an anticoagulant effect and could increase the risk of bleeding in patients who are already receiving anticoagulants. Caution is advised for anyone taking chondroitin with warfarin or other anticoagulants or anti ...
... danaparoid, an anticoagulant that works by inhibiting activated factor X, it might have an anticoagulant effect and could increase the risk of bleeding in patients who are already receiving anticoagulants. Caution is advised for anyone taking chondroitin with warfarin or other anticoagulants or anti ...
Mycobacterium tuberculosis from Tshwane Metropolitan OLUWASEGUN OLAYINKA ATANDA
... Caminero , Cegielski, Danilovits, Espinal, Hollo, Jaramillo, Leimane, Mitnick, Mukherjee, Nunn, Pasechnikov, Tupasi, Wells, Raviglione, 2006). Therefore, rapid detection of resistance to second-line drugs is essential for patient management and effective public health interventions (Ahmad and Mokadd ...
... Caminero , Cegielski, Danilovits, Espinal, Hollo, Jaramillo, Leimane, Mitnick, Mukherjee, Nunn, Pasechnikov, Tupasi, Wells, Raviglione, 2006). Therefore, rapid detection of resistance to second-line drugs is essential for patient management and effective public health interventions (Ahmad and Mokadd ...
Effect of grapefruit juice on bioavailability of montelukast
... Methods: In the first session, volunteers were treated with oral montelukast 10 mg once daily with 250 ml water. After a 10-day washout period, the same volunteers were treated with 10 mg montelukast with 250 ml grapefruit juice. Blood samples were collected 2, 3, and 4 hours after drug administrati ...
... Methods: In the first session, volunteers were treated with oral montelukast 10 mg once daily with 250 ml water. After a 10-day washout period, the same volunteers were treated with 10 mg montelukast with 250 ml grapefruit juice. Blood samples were collected 2, 3, and 4 hours after drug administrati ...
Vol. 28, No. 1 Natural Hallucinogens to Avoid
... In addition, the effects of salvia are unknown when it is used in combination with other substances. 5 Treatment There are few case reports that describe treatment of salvia intoxication. Since the effects are brief in duration, very few people present to hospital under the influence of salvia. Theo ...
... In addition, the effects of salvia are unknown when it is used in combination with other substances. 5 Treatment There are few case reports that describe treatment of salvia intoxication. Since the effects are brief in duration, very few people present to hospital under the influence of salvia. Theo ...
sanofi-aventis Canada Inc. Date of Revision: 2150 St. Elzear Blvd. West
... cause induction of drug metabolizing enzyme systems of the liver. As a result, the rate of metabolism of those drugs which are substrates for these enzymes can be altered, resulting in reduced pharmacological effects of the drugs involved. In patients receiving anticoagulants, it is recommended that ...
... cause induction of drug metabolizing enzyme systems of the liver. As a result, the rate of metabolism of those drugs which are substrates for these enzymes can be altered, resulting in reduced pharmacological effects of the drugs involved. In patients receiving anticoagulants, it is recommended that ...
Clinical Trials: What You Need to Know
... Then, her doctor tells her about a new substance that has been studied and tested in the lab, including animal studies. It looks like it might help her type of cancer. Phase I human studies have not started, but a phase 0 study of the new drug, called “EX-0,” is available. This study will only take ...
... Then, her doctor tells her about a new substance that has been studied and tested in the lab, including animal studies. It looks like it might help her type of cancer. Phase I human studies have not started, but a phase 0 study of the new drug, called “EX-0,” is available. This study will only take ...
RP-HPLC Analysis of Aspirin - Indian Journal of Pharmaceutical
... Antifungal activities of different extracts of Millingtonia hortensis were investigated against various fungal pathogens. Methanol extract was found to have stronger activity than fluconazole against yeast like fungi: 4 fold against Candida krusei with 4 µg/ml minimal inhibitory concentration and 2 ...
... Antifungal activities of different extracts of Millingtonia hortensis were investigated against various fungal pathogens. Methanol extract was found to have stronger activity than fluconazole against yeast like fungi: 4 fold against Candida krusei with 4 µg/ml minimal inhibitory concentration and 2 ...
Summary of Main DRUID Results - Druid
... DRUID activities were implemented in seven scientific Work packages. A description of the problem situation of driving under the influence of psychoactive substance (DUI/DUID) was generated in WP1 and WP2 based on experimental and epidemiological studies, whereas the remaining five Work packages foc ...
... DRUID activities were implemented in seven scientific Work packages. A description of the problem situation of driving under the influence of psychoactive substance (DUI/DUID) was generated in WP1 and WP2 based on experimental and epidemiological studies, whereas the remaining five Work packages foc ...
New Anticoagulants For Stroke Prevention in AF Atrial Fibrillation
... *Dabigatran 150mg twice daily preferred over a vitamin K antagonist. ACCP = American College of Chest Physicians; OAC = Oral anticoagulant. You JJ, et al. Chest. 2012;141:e531S-75S. ...
... *Dabigatran 150mg twice daily preferred over a vitamin K antagonist. ACCP = American College of Chest Physicians; OAC = Oral anticoagulant. You JJ, et al. Chest. 2012;141:e531S-75S. ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.