Lecture 2
... (desensitization) • Decreased response to same dose with repeated exposure • or more drug needed to achieve same effect • Right-ward shift of D-R curve • Sometimes occurs in an acute dose (e.g. alcohol) • Can develop across drugs (crosstolerance) • Caused by compensatory mechanisms that oppose the e ...
... (desensitization) • Decreased response to same dose with repeated exposure • or more drug needed to achieve same effect • Right-ward shift of D-R curve • Sometimes occurs in an acute dose (e.g. alcohol) • Can develop across drugs (crosstolerance) • Caused by compensatory mechanisms that oppose the e ...
Module 13: Drug Abuse Prevention Drugs: Any chemical or
... • Other Problems – Gum disease – More likely to need medications The effects of nicotine on the body --------*******MISSING, WILL ADD********----------- *B.C.* ...
... • Other Problems – Gum disease – More likely to need medications The effects of nicotine on the body --------*******MISSING, WILL ADD********----------- *B.C.* ...
Document
... preference information and two with criteria rankings elicited from an expert in the field of antidepressants. We explained the SMAA model and multi-attribute utility theory to the expert and asked her to consider two scenarios: mild and severe depression. ...
... preference information and two with criteria rankings elicited from an expert in the field of antidepressants. We explained the SMAA model and multi-attribute utility theory to the expert and asked her to consider two scenarios: mild and severe depression. ...
Overview_of_drug_development_cmh_with_animatiions
... “Any chemical agent that affects the processes of living” ...
... “Any chemical agent that affects the processes of living” ...
PowerPoint 簡報
... circulation and travels to various regions of the body, - the drug’s chemistry and ability to cross biologic membranes. - the rate and extent of blood flow - bound form or unbound fraction ...
... circulation and travels to various regions of the body, - the drug’s chemistry and ability to cross biologic membranes. - the rate and extent of blood flow - bound form or unbound fraction ...
Illegal Drugs - cloudfront.net
... 1. Natural Drugs- drugs which come from plants, or plant/animal extracts 2. Synthetic Drugs: drugs which are produced artificially 3. Illicit Drugs: the use or sale of any drug that is illegal, which includes the use or selling of prescription drugs 4. Gateway Drugs- drugs that open the door for oth ...
... 1. Natural Drugs- drugs which come from plants, or plant/animal extracts 2. Synthetic Drugs: drugs which are produced artificially 3. Illicit Drugs: the use or sale of any drug that is illegal, which includes the use or selling of prescription drugs 4. Gateway Drugs- drugs that open the door for oth ...
A. Introduction to drug discovery
... the sulfa drug; sulfanilamide was used as the lead for the development of many sulfa drugs. Aminoglycosides and tetracyclines were discovered after random screening of soil samples on different bacterial strains ...
... the sulfa drug; sulfanilamide was used as the lead for the development of many sulfa drugs. Aminoglycosides and tetracyclines were discovered after random screening of soil samples on different bacterial strains ...
Key Features of the UCLHguide - UCL Hospitals Injectable
... Contents can be hidden so the monograph fills the whole screen ...
... Contents can be hidden so the monograph fills the whole screen ...
HUSC 141 - Community College of Baltimore County
... G. Psychotherapeutic drugs, including over-the-counter drugs and dietary supplements H. Performance-enhancing drugs History of psychoactive substances Drug control policies and trends in legislation The nervous system and neurotransmission Neurochemical effects of each major substance category A. Ph ...
... G. Psychotherapeutic drugs, including over-the-counter drugs and dietary supplements H. Performance-enhancing drugs History of psychoactive substances Drug control policies and trends in legislation The nervous system and neurotransmission Neurochemical effects of each major substance category A. Ph ...
"Obesity Epidemic" (Women`s Media Center 2008)
... gain, diabetes, heart problems, and death in adults, but at least their central nervous systems (CNS) are mature. What is worse is that these same drugs are even less likely to have been tested on anyone younger than adults, and there are exceedingly few longterm studies on toddlers, schoolchildren, ...
... gain, diabetes, heart problems, and death in adults, but at least their central nervous systems (CNS) are mature. What is worse is that these same drugs are even less likely to have been tested on anyone younger than adults, and there are exceedingly few longterm studies on toddlers, schoolchildren, ...
Recently Introduced Products
... Ozurdex can 1) reduce the risk of vision loss and 2) improve the speed and incidence of visual improvement in ...
... Ozurdex can 1) reduce the risk of vision loss and 2) improve the speed and incidence of visual improvement in ...
General Issues
... understand the neurochemical system it interacts with. In other words, we need to understand how Neurotransmitter X - is produced & released from the pre-synaptic neuron - acts on the receptors of the post-synaptic neuron - is removed from the synaptic cleft ...
... understand the neurochemical system it interacts with. In other words, we need to understand how Neurotransmitter X - is produced & released from the pre-synaptic neuron - acts on the receptors of the post-synaptic neuron - is removed from the synaptic cleft ...
![CH1- History - ppt[1]. - Catherine Huff`s Site](http://s1.studyres.com/store/data/008261854_1-6b2dbbb8ad89936bd7dfee1b056548a9-300x300.png)
CH1- History - ppt[1]. - Catherine Huff`s Site
... indomethacin in animal models. The mechanism of action of carprofen, like that of other NSAIDs, is believed to be associated with the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins n ...
... indomethacin in animal models. The mechanism of action of carprofen, like that of other NSAIDs, is believed to be associated with the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins n ...
Diapositiva 1
... clinical trials to prove safety and efficacy. • Recognized that patent protection could be insufficient given the length of the regulatory process. Therefore, in exchange to making possible “me too” approvals, they incorporated a data exclusivity term independent to patent rights and also an excepti ...
... clinical trials to prove safety and efficacy. • Recognized that patent protection could be insufficient given the length of the regulatory process. Therefore, in exchange to making possible “me too” approvals, they incorporated a data exclusivity term independent to patent rights and also an excepti ...
Слайд 1 - Promo-med
... Hypertension. Chronic heart failure (NYHA class II to IV) in patients receiving standard therapy, including diuretics, digitalis preparations, as well as ACE inhibitors or beta-blockers (not simultaneously). The use of Valsaforce®: Significantly reduces the risk of cardiovascular events, including r ...
... Hypertension. Chronic heart failure (NYHA class II to IV) in patients receiving standard therapy, including diuretics, digitalis preparations, as well as ACE inhibitors or beta-blockers (not simultaneously). The use of Valsaforce®: Significantly reduces the risk of cardiovascular events, including r ...
Drug Discovery and Development
... will also avoid products that would be consumed by individuals of lower economic status (i.e. a disease which only affects third world countries) ...
... will also avoid products that would be consumed by individuals of lower economic status (i.e. a disease which only affects third world countries) ...
No Slide Title
... therapy is the rule, not the exception for almost all medications. • Research in the past 5- 15 years has identified many sources of inter-patient variability- which can be used for drug and dosage selection. • New knowledge, particularly in the area of pharmacogenetics, is progressing at a rapid ...
... therapy is the rule, not the exception for almost all medications. • Research in the past 5- 15 years has identified many sources of inter-patient variability- which can be used for drug and dosage selection. • New knowledge, particularly in the area of pharmacogenetics, is progressing at a rapid ...
Drug consumption statistics
... the DDD for oral aspirin equals 3 grams, which is the assumed maintenance daily dose to treat pain in adults. DDDs do not necessarily reflect the average daily dose actually used in a given country. DDDs can be aggregated within and across therapeutic classes of the Anatomical ...
... the DDD for oral aspirin equals 3 grams, which is the assumed maintenance daily dose to treat pain in adults. DDDs do not necessarily reflect the average daily dose actually used in a given country. DDDs can be aggregated within and across therapeutic classes of the Anatomical ...
Enzymes - ISpatula
... 1) prodrug, but it is a chemical modification on the parent drug, if we do this then we are forming new chemical entity so we need to study everything related to this compound like a new drug, like starting a new drug discovery trip with a huge bill because we need to prove that drug A is the same a ...
... 1) prodrug, but it is a chemical modification on the parent drug, if we do this then we are forming new chemical entity so we need to study everything related to this compound like a new drug, like starting a new drug discovery trip with a huge bill because we need to prove that drug A is the same a ...
MPhS ANNUAL REPORT 2014
... Background: One of the elements of Good Pharmacy Practice is the doctor-patientpharmacist cooperation. To ensure that this relationship was of high quality and contributed to improving the quality of patient care, it is important to understand what patients want to know about pharmacotherapy. It is ...
... Background: One of the elements of Good Pharmacy Practice is the doctor-patientpharmacist cooperation. To ensure that this relationship was of high quality and contributed to improving the quality of patient care, it is important to understand what patients want to know about pharmacotherapy. It is ...
Research Pharmacy
... clinical trials? To obtain data to present to the FDA ! Drug companies are trading drug (and medical care) for data on patient outcomes ...
... clinical trials? To obtain data to present to the FDA ! Drug companies are trading drug (and medical care) for data on patient outcomes ...
... As a member of the Alliance for Microbicide Development, we support their recommendation to review the current guidelines for consistency; systematically examine them in light of the latest evolving knowledge; and incorporate new information. We also support the need for clear, consistent and efllci ...
Drug Metabolism and Variability among Patients in Drug Response
... response among patients are common, often leading to challenges in optimizing a dosage regimen for an individual patient. Most major drugs are effective in only 25 to 60 percent of patients, and more than 2 million cases of adverse drug reactions occur annually in the United States, including 100,00 ...
... response among patients are common, often leading to challenges in optimizing a dosage regimen for an individual patient. Most major drugs are effective in only 25 to 60 percent of patients, and more than 2 million cases of adverse drug reactions occur annually in the United States, including 100,00 ...
New Psychoactive Substances – DAWG JUNE 2014
... No guarantee that different batches of same product will contain (a) same dose of drug, or (b) even same drug ...
... No guarantee that different batches of same product will contain (a) same dose of drug, or (b) even same drug ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.