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Technical Guide for countries to set targets for universal
Technical Guide for countries to set targets for universal

... as prisons. It is important to define the scope of the areas or settings under consideration. While this Technical guide focuses primarily on IDUs, it may also be useful for setting targets for HIV interventions targeting problematic drug users who do not inject but who are at risk of starting to do ...
Transungual Drug Delivery: An Overview
Transungual Drug Delivery: An Overview

... Urea or a combination of urea and salicylic acid has been used for nonsurgical avulsion (chemical avulsion) in clinical studies, prior to topical treatment of onychomycosis (Hettinger and Valinsky, 1991). Nail abrasion, using sandpaper nail files, prior to antifungal nail lacquer treatment may decre ...
Thalidomide in Children Undergoing Bone Marrow Transplantation: Series at a
Thalidomide in Children Undergoing Bone Marrow Transplantation: Series at a

... Thalidomide in Children Undergoing Bone Marrow Transplantation: Series at a Single Institution and Review of the Literature ABSTRACT. Thalidomide has one of the most notorious drug histories because of its teratogenicity. Its widespread use in the 1960s led to a worldwide epidemic of phocomelia in ...
Polyethylene Glycol 3350 (PEG 3350) Frequently Asked
Polyethylene Glycol 3350 (PEG 3350) Frequently Asked

... Several research studies have shown PEG 3350 to be safe in children when used for several weeks to several months. Currently there have been no studies specifically on the use and safety of PEG 3350 in children for longer periods of time. In clinical practice, however, it is common for pediatric gas ...
Cathinone derivatives: A review of their chemistry, pharmacology
Cathinone derivatives: A review of their chemistry, pharmacology

... widespread phenomenon later in the decade.[17] Mephedrone (4methylmethcathinone) became commonplace via these outlets in 2007 and 2008. It seems that mephedrone originally became available in Israel, but its production ceased in 2008 when the Israeli government banned it. This was followed by an unp ...
efavirenz - WHO archives - World Health Organization
efavirenz - WHO archives - World Health Organization

... children had received treatment. A prospective observational cohort study was undertaken to assess the feasibility, effectiveness, adherence, toxicity and viral resistance of antiretroviral therapy. The clinical and biological results of the study were comparable to those seen in western cohorts, de ...
Efficacy of Lidocaine Iontophoresis Using Either Alternating or Direct
Efficacy of Lidocaine Iontophoresis Using Either Alternating or Direct

... level. Moreover, pH changes did not occur in vivo study possibly because the silver/silver chloride electrodes prevented pH variation. Owing to the polarization of the skin or electrodes surface and formation of insoluble silver chloride, the effective current flow was limited. Additionally, the ski ...
product monograph including patient
product monograph including patient

...  Patients who are hypersensitive to this drug, other nitrates or to any ingredient in the formulation or component of the container. For a complete listing, see the Dosage Forms, Composition and Packaging section of the product monograph.  Allergy to the adhesive used in nitroglycerin patches has ...
Lorena-Botero-Calderon et al. Advances in the
Lorena-Botero-Calderon et al. Advances in the

... Fluconazole represents the only triazole agent that has been extensively used in NICUs, where C. albicans and C. parapsilosis are the predominant pathogens [55]. However, in recent years, resistance to fluconazole has appeared, with some centers reporting ~ 8% of resistance among Candida isolates [5 ...
10.4103-2229-4708.97718
10.4103-2229-4708.97718

... Atchuta Kumar, et al.: A related substance HPLC method for candesartan cilexetil tablets ...
Patient Information Sheet YOUR PRESCRIPTION FOR BALACET
Patient Information Sheet YOUR PRESCRIPTION FOR BALACET

... Blood gases, pH, and electrolytes should be monitored in order that acidosis and any electrolyte disturbance present may be corrected promptly. Acidosis, hypoxia, and generalized CNS depression predispose to the development of cardiac arrhythmias. Ventricular fibrillation or cardiac arrest may occur ...
Epclusa - Gilead
Epclusa - Gilead

... combination with daclatasvir or simeprevir. A fatal cardiac arrest was reported in a patient taking amiodarone who was coadministered a sofosbuvir-containing regimen (HARVONI (ledipasvir/sofosbuvir)). Bradycardia has generally occurred within hours to days, but cases have been observed up to 2 weeks ...
Lipid nanoparticles for topical and transdermal application for
Lipid nanoparticles for topical and transdermal application for

... have been developed to penetrate the SC. These nanoparticles have proved to be effective in dermal application of cosmetic and pharmaceutical forms, showing beneficial properties such as: drug delivery and controlled release; increase in skin penetration and skin hydration, and an excellent toleranc ...
Naproxen with Esomeprazole Independent Review, May 2013
Naproxen with Esomeprazole Independent Review, May 2013

... There was one meeting of all reviewers with the Convenor, and a regular teleconference with each reviewer to monitor progress. The Primary Reviewer also met weekly with [names of reviewers redacted]. ...
Report to the Minister of Justice and Solicitor
Report to the Minister of Justice and Solicitor

... “clozapine toxicity” and the “manner of death” as “undetermined”. In the Autopsy Report he said: “...At Autopsy, no injuries and no obvious natural diseases were identified to account for death. In particular, there was no inflammation of the heart muscle (myocarditis) and no enlargement of the hear ...
Nephrotoxicity as a cause of acute kidney injury in children
Nephrotoxicity as a cause of acute kidney injury in children

... rare with penicillins and uncommon with cephalosporins, is a greater risk with the penems. The true incidence of βlactam-antibiotics-induced AKI is unknown, as is how often it occurs when the antibiotic is used as monotherapy or in combination with other nephrotoxic drugs. Mechanisms of injury inclu ...
St. John`s Wort - American Botanical Council
St. John`s Wort - American Botanical Council

... ADMINISTRATION ...
Version 7
Version 7

... and consistently with or without food. If buspirone is administered with a potent CYP3A4 inhibitor, the initial dose should be lowered and only increased gradually after medical evaluation (see section 4.5). Grapefruit juice increases the plasma concentrations of buspirone. Patients taking buspirone ...
JANUARY 1, 2015 TREATMENT AUTHORIZATION (TAR) CRITERIA
JANUARY 1, 2015 TREATMENT AUTHORIZATION (TAR) CRITERIA

... Note that criteria apply to the drug entity specified by the generic name, and that brand (trade) names are shown for reference or example only; additional criteria apply to brand requests when generic is available. ...
PRODUCT INFORMATION NUELIN SR TABLETS
PRODUCT INFORMATION NUELIN SR TABLETS

... Nuelin SR is a sustained release formulation appropriate for long term use. Steady-state conditions are usually achieved after 4 days' therapy. It is now generally believed that plasma concentrations of 10-20 µg/mL constitute a therapeutic range, although some patients may benefit from levels below ...
RP-HPLC METHOD DEVELOPMENT AND
RP-HPLC METHOD DEVELOPMENT AND

... management does not give preference to carvedilol over other beta-blockers.The most common side effects include dizziness, fatigue, hypotension, diarrhea, asthenia, bradycardia, and weight gain.[5]A case report of a patient with panic disorder associated sleep disturbances and nightmares with the im ...
PrVIBRAMYCIN* CAPSULES
PrVIBRAMYCIN* CAPSULES

... Antacids containing aluminum, calcium or magnesium impair absorption and should not be given to patients taking VIBRAMYCIN/VIBRA-TABS. The concurrent use of VIBRAMYCIN/VIBRA-TABS (doxycycline hyclate) with alcohol, barbiturates, phenytoin and carbamazepine (hepatic enzyme inducers) has been reported ...
Effective Over-the-Counter Acne Treatments
Effective Over-the-Counter Acne Treatments

... (Benzaclin, Dermik Laboratories, Inc., Berwyn, PA; Duac, Stiefel Laboratories, Inc., Duluth, GA; Benzamycin, Dermik Laboratories) are more effective for acne than BPO or the topical antibiotic alone. In this regard, a patient who reports improvement with an OTC BPO product might benefit even further ...
Simvastatin
Simvastatin

... Before initiating therapy with simvastatin, secondary causes for elevated cholesterol values, such as obesity, poorly controlled diabetes mellitus, hypothyroidism, nephrotic syndrome, obstructive liver disease, or drug therapy, should be excluded. It is important to determine whether increased level ...
The practice of digoxin therapeutic drug monitoring - BN6Team-10
The practice of digoxin therapeutic drug monitoring - BN6Team-10

... concentration to drop to within the therapeutic range. In renal impairment with a prolonged digoxin half-life, doses may need to be withheld for several days. When the measured digoxin concentration is low, options include stopping treatment, increasing the dose or making no change. If the indicatio ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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