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Product Monograph
Product Monograph

... ZOCOR® is indicated as an adjunct to diet, at least equivalent to the American Heart Association (AHA) Step 1 diet, for the reduction of elevated total cholesterol (total-C) and Low-Density Lipoprotein-cholesterol (LDL-C), apolipoprotein B (apo B), and triglycerides (TG) levels in patients with prim ...
SERC PM
SERC PM

... For management of a suspected drug overdose, contact your regional Poison Control Centre. A few overdose cases (up to 640 mg), with mild to moderate symptoms of nausea, dry mouth, dyspepsia, abdominal pain and somnolence have been reported. Presumably, more serious complications (e.g. convulsion, pu ...
PK/PD - Physiologie et Thérapeutique Ecole Véto Toulouse (ENVT)
PK/PD - Physiologie et Thérapeutique Ecole Véto Toulouse (ENVT)

... the half-life is long, the best predictor is always AUC/MIC whatever the antibiotic. • These kind of results are very important for veterinary medicine that uses many long-acting formulations and the use of AUC/MIC as a universal PK/PD index would greatly facilitate many tasks such as finding an opt ...
VALIDATED HPLC METHOD FOR SIMULTANEOUS QUANTITATION OF TADALAFIL AND
VALIDATED HPLC METHOD FOR SIMULTANEOUS QUANTITATION OF TADALAFIL AND

... using UV detection at 229 nm. This method has been applied to formulation without interference of excipients of formulation. The linear regression analysis data for the calibration plots showed a good linear relationship over the concentration range of 0.25-4 µg/mL for Tadalafil and 0.75-12 µg/mL fo ...
Powder - Farmasi Unand
Powder - Farmasi Unand

... Wide choice of ingredients & varying doses can be prescribed to fulfill the individual patient needed It is convenient for the physician to prescribe a specific amount of powder Each dose can contain a different amount of active drug Easy to carry ...
KEGG for integration and interpretation of large
KEGG for integration and interpretation of large

... genomic revolution to society. To meet the needs of translational bioinformatics the KEGG resource is being integrated with disease and drug information used in clinical practice and in wider society, such as the package inserts of marketed drugs. It is hoped that KEGG will assist scientists to tran ...
Management of Hypertension - Kementerian Kesihatan Malaysia
Management of Hypertension - Kementerian Kesihatan Malaysia

... Dramatic results in uncontrolled experiments (such as the results of the introduction of penicillin treatment in the 1940s) could also be regarded as this type of evidence ...
MARTINDALE - The Complete Drug Reference Danazol
MARTINDALE - The Complete Drug Reference Danazol

... of direct value.9-11 Conservative surgery may be of benefit in mild disease,10 and is generally recommended in more severe cases.1,9 Assisted reproductive techniques (see Infertility, Hypothalamic and Pituitary Hormones) offer the best chance of conception in more severe disease1,9,10 but the extent ...


... Doxycycline 100 mg capsules should be administered with adequate amounts of fluid. This should be done in the sitting or standing position and well before retiring at night to reduce the risk of oesophageal irritation and ulceration. If gastric irritation occurs, it is recommended that Doxycycline 1 ...
Aloe vera: Plant of Immortality - International Journal of Pharma
Aloe vera: Plant of Immortality - International Journal of Pharma

... Aloe vera gel should not be used externally after laparotomy or caesarean delivery because it may delay wound healing. Drug aloe should not be taken for more than 10 days. It should not be used by pregnant or lactating women and is contraindicated in the following conditions: intestinalobstruction o ...
Cytochrome P4502C9: an enzyme of major importance in human
Cytochrome P4502C9: an enzyme of major importance in human

... one cationic binding site [24]. Interestingly, dibenzo[a,h]anthracene and benzo[a]pyrene have been identified recently as CYP2C9 substrates [25, 26]. Unlike most drug substrates for CYP2C9, these neutral, highly hydrophobic compounds do not possess an acidic functional group (or indeed any functiona ...
Martindale: The Complete Drug Reference
Martindale: The Complete Drug Reference

... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
Fixed Combinations of Glaucoma Medications
Fixed Combinations of Glaucoma Medications

... When initiating medical therapy for newly diagnosed glaucoma, it is typically desirable to begin with a single antiglaucoma medication [1]. Topical medical therapy remains the firstline treatment in the management of glaucoma, but over time monotherapy often fails to control intraocular pressure (IO ...
Drug Formulary
Drug Formulary

... low (return of reflex requiring repeated administration of drugs) for the procedure, an RAR veterinarian should be contacted. With veterinary consultation, further flexibility can be provided to more accurately titrate dosages prior to submitting a protocol modification to the Institutional Animal C ...


... upper abdomen, oropharynx and inhaler mouthpiece and the amount that the subject expired into an exhalation filter trap were measured by gamma scintigraphy. Study 2: asthmatic patients. This was an open-label study examining the lung deposition of radiolabelled HFA–BDP (50 µg strength) and utilizing ...
Cytochrome P450 Inhibition
Cytochrome P450 Inhibition

... Overview ...
Free PDF - European Review for Medical and
Free PDF - European Review for Medical and

... estimate6, in USA there were 3.03 millions of atrial fibrillation patients and this figure could reach 7.56 millions in 2050. Atrial fibrillation is a strong risk factor for ischaemic stroke (approximately 3- to 5-fold excess risk), with associated clinical problems and increased mortality rates (1. ...
Epinephrine_1871-01_PI_Art3 without Legend
Epinephrine_1871-01_PI_Art3 without Legend

... Adverse events experienced as a result of accidental injections may include increased heart rate, local reactions including injection site pallor, coldness and hypoesthesia or injury at the injection site resulting in bruising, bleeding, discoloration, erythema or skeletal injury. Lacerations, bent ...
Licorice - Glycyrrhiza glabra
Licorice - Glycyrrhiza glabra

... Therefore, the German health authorities warn that licorice should not be used for more than four to six weeks in therapeutic doses, without medical advice. During this period of time, a diet rich in potassium (such as bananas and dried apricots) is recommended. The potassium loss can also produce i ...
Introduction
Introduction

... shown in table 1. Plasma concentration data were fit to a two compartment (biexponential) model, after applications of residual methods. Calculated pharmacokinetic parameters are reported in table 2. In table 3, the median, minimum, and maximum values of plasma concentration of ranitidine of the new ...
Mrs - Vitrodiagnostic.com
Mrs - Vitrodiagnostic.com

... control the bacterial flora of the mouth; 2. to supply enzymes destinated to play an important role in preparing food for digestion; 3. to produce hormones and other pharmacologically active compounds; 4. to wet the fur of animals with saliva in response to heat stress, thereby obtaining the same co ...
Naloxone: Frequently Asked Questions
Naloxone: Frequently Asked Questions

... treatment. There is, however, less risk of overdose than with other opioids. Most buprenorphine overdoses involve intravenous injection and/or combination of buprenorphine with other drugs, particularly sedatives, benzodiazepines or neuroleptics. Unfortunately, naloxone doesn’t work as well for bupr ...
Influence of Vesicle Size, Lipid Composition, and
Influence of Vesicle Size, Lipid Composition, and

... and SUVs have been utilized with lipid compositions incorpo rating varying amounts of positively charged and negatively charged lipids in addition to PC and cholesterol. The resulting drug-to-lipid ratios vary by a factor of 17 and trapping efficien cies range from 4 to 90% (Table 1). The variations ...
Opioid Receptors and Legal Highs - The Salvia divinorum Research
Opioid Receptors and Legal Highs - The Salvia divinorum Research

... and Malaysia by manual laborers to enhance productivity, and for its euphoric (also called “coca-like”) effect at low doses (33). At higher doses, Kratom has opioid-like effects, and its use to treat pain and opium withdrawal was described as early as the nineteenth century (32). In Thailand, the us ...
Warfarin-herb interactions: a review and study based on assessment
Warfarin-herb interactions: a review and study based on assessment

... adults in developed countries and more than 60% Asians use herb as an alternative medicines (Zhou, 2007; Anonymous, 2006). Despite widespread use of herbal remedies, scientific data about their safety and efficacy are lacking in most cases plus reporting of adverse drug events is currently limited. ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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