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Structure Physiology of blood pressure and heartbeat
Structure Physiology of blood pressure and heartbeat

... Cardiac cycle: Heart sounds • Cause = forceful closure of valves by high pressure blood • 1st heart sound: lubb – Beginning of systole; results from closure of AV valve ...
hypertrophic cardiomyopathy diagnosis and management
hypertrophic cardiomyopathy diagnosis and management

... 1. Drug-refractory heart failure symptoms 2. NYHA Classes III and IV 3. LV outflow obstruction – Rest - gradient ≥ 30 mm Hg – Physiologic exercise - gradient ≥ 50 mm Hg ...
MY HEART SKIPS A BEAT - Cardiology at Concorde
MY HEART SKIPS A BEAT - Cardiology at Concorde

... may signify “cardiac consciousness” or awareness of our normal heartbeat, which taken with other evidence can lead to the conclusion of a benign diagnosis. In these instances, elimination of the adrenaline releasing stressors mentioned above can be helpful. In some instances, we find that the sympt ...
To continue or not to continue use of statins in patients with
To continue or not to continue use of statins in patients with

... Statin has been shown to prevent new onset CHF Statin decreasing levels of TC lead to poor prognosis? Statin used after diagnosis NYHA class III, IV? Studies and evaluation needed to describe risk/benefit in pharmacologically induced low TC (statin) vs naturally low TC ...
PowerPoint Presentation - Weber State University
PowerPoint Presentation - Weber State University

... diastole, atrial systole] Isovolumetric Contraction Period [ventricular systole] Ventricular Ejection Period [ventricular systole] Isovolumetric Relaxation Period [ventricular diastole, atrial diastole] ...
CPR
CPR

... Repeat Back Blows and Abdominal Thrusts -until the object is forced out, the victim can breathe, or the victim becomes unconscious. ...
Significance of myocardial mass and volume geometry evaluated by
Significance of myocardial mass and volume geometry evaluated by

Frank-Starling “Law of the Heart”
Frank-Starling “Law of the Heart”

... •fibers arranged in a latticework •is striated •each cell has one nucleus •has typical myofibrils that contain actin and myosin filaments •functions as a Syncytium; intercalated discs and gap junctions •autorhythmic cells and action potentials of longer duration and longer refractory period ...
Form
Form

... (check all that apply) 50-69% stenosis with sig FFR/IVUS Chronic total occlusion is only stenosis Prior CABG - 3VD & multiple graft failure LIMA used - no longer functional LIMA used - patent to native coronary ...
Sudden cardiac death in Children participating in organised sport
Sudden cardiac death in Children participating in organised sport

... There has been concern in the media about sudden cardiac death in children during sport, particularly following the collapse of Fabrice Muamba. There are calls being made that all children should be screened prior to taking part in sport. Whilst every child dying is a tragedy, it is often not preven ...
The continuing role of beta-blockers in hypertension
The continuing role of beta-blockers in hypertension

... what has, after all, been a tried and trusted approach to anti-hypertension therapy for many years, it is important that we ensure that these new findings are truly applicable to our own patients and the treatments we currently prescribe. The first thing to point out is that atenolol, as used in ASC ...
Electrical System of the heart
Electrical System of the heart

... ...
Heart failure
Heart failure

... Acute left heart failure Acute de novo left ventricular failure presents with a sudden onset of dyspnoea at rest that rapidly progresses to acute respiratory distress, orthopnoea and prostration. The precipitant, such as acute MI, is often apparent from the history .The patient appears agitated, pal ...
Coronary rehabilitation programmes in Europe are underused, `with
Coronary rehabilitation programmes in Europe are underused, `with

... than half (44.8%) of all patients with coronary heart disease (CHD) were advised to follow a rehabilitation programme, but only one-third (36.5%) took part in some form of cardiac rehabilitation. Yet, of those who were advised to attend a programme, four-fifths agreed and did so. The EUROASPIRE surv ...
Very-Low-Calorie Diet Increases Myocardial
Very-Low-Calorie Diet Increases Myocardial

... the biochemical parameters have previously been described (1,3,4). For statistical analysis, within-group changes were assessed using paired sample t tests and nonparametric tests for normally and nonnormally distributed variables, respectively, using SPSS (version 17.0; SPSS, Chicago, IL). Data are ...
Volume 1, Issue 1, January 2017
Volume 1, Issue 1, January 2017

... Chairman of Steering Committees and in this position has played a fundamental role in our recognition of beneficial effects of beta-blockers , renin-angiotensin inhibitors and aldosterone antagonists in heart failure, the cornerstones of current medical therapy. Moreover, Henry Krum had an interest ...
BUKOVINІАN STATE MEDICAL UNIVERSITY
BUKOVINІАN STATE MEDICAL UNIVERSITY

... profile, AST, albumin and thyroid-stimulating hormone (TSH) 12-lead electrocardiogram and chest radiograph All patients should have an objective determination of LVEF by transthoracic echocardiogram (preferred as it also provides information on cardiac dimensions, valvular function and may suggest t ...
Care of the Left Ventricular Assist Device Patient
Care of the Left Ventricular Assist Device Patient

... Continuous-flow Left Ventricular Assist Devices in Advanced Heart Failure. The Journal of Heart and Lung Transplantation. 29 ...
Enlarged Heart - Shaw American
Enlarged Heart - Shaw American

... The cardio‐thoracic (CT) ratio as determined by chest Xray (CXR) is often used to report heart  size. CT is the heart width divided by the width of the chest cavity. Normal CT ratio is under  50%. Echocardiogram, MUGA scan and ventriculogram are better than chest Xray for assessing  heart size. When ...
CHAP 20c - Dr. Gerry Cronin
CHAP 20c - Dr. Gerry Cronin

... • Exercise draws upon the cardiac reserve to meet the body’s increased physiological demands and maintain homeostasis. ...
Conduction system and Pacemaker
Conduction system and Pacemaker

... conduction system causing ventricular contraction when it enters the ventricular muscle mass. The impulse doesn't go straight through the entire heart because of a layer of connective tissue that insulates the atria from the ventricles. The delay at the AV node is important because it allows the ven ...
Evidence-based Approach to Treatment of Ventricular Arrhythmias
Evidence-based Approach to Treatment of Ventricular Arrhythmias

Section 5: Management of Asymptomatic Patients with Reduced Left
Section 5: Management of Asymptomatic Patients with Reduced Left

... due to a family history of dilated cardiomyopathy, the incidence of ALVD is likely much higher. Prognosis. Patients with ALVD have approximately half the mortality rate (5% annualized) of those with overt symptoms of HF, but their risk of death is 5 to 8 times higher than a normal age-matched popula ...
implantable Cardioverter Defibrillators (ICDs)
implantable Cardioverter Defibrillators (ICDs)

... or “heart failure” have a greater chance of having one of the dangerous fast heart rhythms that ICDs treat. Therefore, ICDs are often recommended for people who have this problem (often described as a “reduced left ventricular ejection fraction” or “LVEF less than 35%” with 55% being the normal valu ...
GUIDELINE Heart Failure Society of South Africa (HeFSSA
GUIDELINE Heart Failure Society of South Africa (HeFSSA

... • Class I – cope without symptoms • Class II – climb 1 flight at normal pace • Class III – climb <1 flight • Tolerance of uphill • Class I – cope without symptoms • Class II – symptomatic on walking uphill • Class III – symptomatic on any incline. Limitations of the NYHA classification includ ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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