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Profile Documents Logout
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-handouts
-handouts

... •  Other  Medica6on  that  may  be  indicated:    Aldosterone  Antagonists,  Digitalis,   Hydralazine/nitrates   •  Implantatable  Cardioverter  Defibrillator   •  Cardiac  Resynchroniza6on  (biventricular  PM)   ...
End-stage chronic heart failure - International Society of Drug Bulletins
End-stage chronic heart failure - International Society of Drug Bulletins

... studies are also addressing the use of CRT in patients who do not meet the standard criteria. Implantable cardioverter defibrillator (ICD) Implantable cardioverter defibrillators are the other important component of device therapy in heart failure to prevent sudden cardiac death, although they are n ...
Canine Heart Problems - Online CPD Courses for Veterinary Nurses
Canine Heart Problems - Online CPD Courses for Veterinary Nurses

... Third degree AV block, also known as complete heart block, is a problem with the conduction system of the heart. The sinoatrial node fires, but is blocked at the AV node. To keep the dog alive, there is a slow ventricular rate, but this can stop at any time. Why does this happen? Most commonly there ...
Restrictive Cardiomyopathy (RCM)
Restrictive Cardiomyopathy (RCM)

... Genes are packages of genetic information that tell our bodies how to develop and function. RCM can be caused by a change or mutation in a gene that encodes proteins important for the contraction or squeeze of the heart muscle. Most often, RCM is inherited. A parent that carries a gene mutation will ...
Slide 1
Slide 1

... and mechanisms for effective knowledge transfer and training.  Developing competency frameworks that are fully supported by high quality education and training programmes and research where required. • Support the uptake of CR in groups that are currently not represented or are under-represented • ...
Control of heart rate
Control of heart rate

... If the SAN stops working, the heart cannot contract, and so death is inevitable. This is why an artificial pacemaker would be fitted to a patient. The SAN is the natural pacemaker, but an artificial pacemaker is capable of sending signals to the heart to keep it contracting and to keep blood flowing ...
Abnormal ecg readings
Abnormal ecg readings

... • A constant PR interval that is usually of normal duration with random dropped beats – In the case of type 2 block, atrial contractions are not regularly followed by ventricular contraction ...
Module 3 - 666 KB
Module 3 - 666 KB

... ventricular function, which are characteristic of diastolic heart failure. This will not change the treatment approach, however. It is possible but unlikely that the systolic murmur represents aortic stenosis or hypertrophic cardiomyopathy. Even if present, these probably are not hemodynamically sig ...
Acute heart failure syndrome
Acute heart failure syndrome

... use of furosemide (Lasix®), a loop diuretic with rapid onset of action. Diuretics can either be given as a bolus method or as a continuous intravenous infusion, with equal efficacy. Other loop diuretics can be used, such as torasemide. The loop diuretics can have detrimental effects, such as worseni ...
Your Answer - University of Florida
Your Answer - University of Florida

... C. Descending aorta D. Pleural line 4. What can pericardial effusions be mistaken for in the anterior portions of the heart? A. Chest wall tissue B. Anterior fat pad C. Rib shadows D. Pleural line 5. If a pericardial effusion is seen surrounding the heart in the parasternal short axis at the mitral ...
Heart failure with Preserved Ejection Fraction
Heart failure with Preserved Ejection Fraction

... administration highlighting the fundamental differences in cardiac physiology between these two types of heart failure. The consequences of increased ventricular stiffening are most evident during physical exertion or exercise. Stroke volume reserve is diminished as a result of inefficient ventricul ...
Nursing Consideration
Nursing Consideration

... A - baseline PT should be drawn before anticoagulation therapy B -e sure to apply direct pressure to the venipuncture site C -oncurrent warfarin therapy with heparin therapy can lengthen the PT D -iets high in green leafy vegetables can shorten PT E -xpect 1.5 to 2 times longer PT if on anticoagulat ...
Section 15: Management of Heart Failure in Special Populations
Section 15: Management of Heart Failure in Special Populations

... are limited concerning the efficacy of beta blockade in the elderly. However, a retrospective analysis of a study of metoprolol CR/XL, which enrolled patients up to age 80 and included a substantial subgroup of elderly patients, found a similar degree of morbidity and mortality reduction in patients ...
Heart
Heart

... The normal ECG consists of a P wave, a QRS complex, and a T wave. The P wave, which is the result of action potentials that cause depolarization of the atrial myocardium, signals the onset of atrial contraction. The QRS complex is composed of three individual waves: the Q, R, and S waves. The QRS co ...
PATIENTS THAT MAY BENEFIT
PATIENTS THAT MAY BENEFIT

... Stimulates from the inside of the left ventricle. Endocardial pacing is considered more physiological – delivering improved electrical and haemodynamic response.12,13,14 ...
Left ventricular assist devices in end
Left ventricular assist devices in end

... These small studies require validation with randomized clinical trials to establish scientific proof. Adjunct medical therapies, such as the addition of phosphodiesterase inhibitors and endothelin receptor blockers, have also shown additional benefits in reducing secondary PH.12,13 In a small study ...
Serial ECG Analysis after Myocardial Infarction: When Heart Failure
Serial ECG Analysis after Myocardial Infarction: When Heart Failure

... blockers, and fluid management are only introduced when clinical signs of HF have become immanent[7] and the patient is already in HF stage C. Obviously, waiting for symptoms of HF implies that the process of developing HF has already been started and that potentially structural damage (ventricular ...
18 Fr - CRTOnline
18 Fr - CRTOnline

... Procedural success has markedly improved over time Successful implant defined as no conversion to surgery or device-related mortality during the procedure and proper valve function immediately post-implant. The 18Fr S&E uses technical success (procedural success in re-adjudicated data was ...
CPR Facts and Statistics
CPR Facts and Statistics

Ongoing myocardial damage relates to cardiac sympathetic nervous
Ongoing myocardial damage relates to cardiac sympathetic nervous

... severity, H-FABP was released from the damaged myocardium at each stage of heart failure (Fig. 1). Although several parameters of 123I-MIBG imaging provide promising information to assess patients with heart failure,7–13 the precise mechanism that underlies these findings has not yet been establishe ...
Basic Pacing Concepts Part I
Basic Pacing Concepts Part I

... Medtronic pacemakers are indicated for rate adaptive pacing in patients who may benefit from increased pacing rates concurrent with increases in activity (Thera, Thera-i, Prodigy, Preva and Medtronic.Kappa 700 Series) or increases in activity and/or minute ventilation (Medtronic.Kappa 400 Series). M ...
successes, challenges and next steps.
successes, challenges and next steps.

... • diabetes, • hypertension, • chronic kidney disease, • pacemaker implantation, • CABG or PCI ...
File - Developing Anaesthesia
File - Developing Anaesthesia

... It has limited effectives however and is currently limited to patients who have coexisting illnesses that are contraindications to other therapies or those who require pacing for bradycardia. ...
Pharmaco-invasive vs. facilitated percutaneous coronary intervention strategies for ST-segment-
Pharmaco-invasive vs. facilitated percutaneous coronary intervention strategies for ST-segment-

... artery patency rates being higher with lytic-based treatments, no mortality benefit, but more bleeding complications, was observed. The pre-PCI patency rates with upfront abciximab or high-bolus dose tirofiban alone were also not higher than with placebo, but more complete ST-segment resolution and/ ...
CHF Trials Update and Surrogate Endpoints
CHF Trials Update and Surrogate Endpoints

... • Epidemiology (prevalence, incidence, trends) • Epidemiology (mortality and associated morbidity) • Risk factors ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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