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CardioWest total artificial heart (TAH) (September 2005)
CardioWest total artificial heart (TAH) (September 2005)

... Although survival rates have improved significantly, nearly half the patients diagnosed with heart failure will die within five years (Goldstein et al. 1998). Lifestyle modifications, a range of pharmacological treatments, and sometimes surgical treatments, are used to treat congestive heart failur ...
TMT
TMT

... Prevalence of abnormal TMT in asymptomatic middle aged men ranges from 5-12%. Appropriate asymptomatic subjects would be those with an estimated annual risk greater than 1 or 2% per year. Symptomatic patients Exercise should be routinely performed in patients with chronic ischemic heart disease befo ...
Looking Beyond the Ablation Shore, Treating Atrial
Looking Beyond the Ablation Shore, Treating Atrial

... increased sympathetic drive converting to a vagal predominance and AF onset (7,8). Decades of large animal work by the University of Oklahoma group has demonstrated a relationship between the autonomic nervous system and phenomena related to AF initiation and maintenance (9–11). This relationship is ...
Anatomy of the Cardiovascular System
Anatomy of the Cardiovascular System

... Tricuspid valve  Bicuspid valve (mitral valve) ...
Arrhythmic Complications of MI
Arrhythmic Complications of MI

... – Mortality is mostly related to the amount of muscle loss – In 40% of patients, a trifascicular block progresses to a complete heart blockrate of progression unknown ...
pulse oximeter and cardiac monitor handout
pulse oximeter and cardiac monitor handout

... and increased 2,3-DPG or 2,3 BPG. ...
PowerPoint 演示文稿 - Shandong University
PowerPoint 演示文稿 - Shandong University

... Sympathetic nerve (norepinephrine) or the epinephrine and norepinephrine (adrenal gland) enhance the strength and the velocity of the cardiac contraction. The change of myocardial property is independent of the preload. We call it the contractility. Importance: exert a long – time influence on the c ...
Circulatory System
Circulatory System

... • Tachycardia: Heart rate in excess of 100bpm • Bradycardia: Heart rate less than 60 bpm • Sinus arrhythmia: Heart rate varies 5% during respiratory cycle and up to 30% during deep respiration • Premature atrial contractions: Occasional shortened intervals between one contraction and succeeding, fre ...
Mechanisms of Tachycardia
Mechanisms of Tachycardia

... Treating Ventricular Tachyarrhythmias ● Pharmacological therapy (works on action potential) ● Ablation ○ Can be curative in some cases ○ Most effective in early stages of disease ● Device-based options ● Combination therapy ○ Drugs to control tachycardia and reduce ambient arrhythmias ○ Defibrillat ...
Sudden Cardiac Death Fact Sheet
Sudden Cardiac Death Fact Sheet

... activity of the heart. An echocardiogram, which is an ultrasound test to allow for direct visualization of the heart structure, will likely also be done. The specialist may also order a treadmill exercise test and a monitor to enable a longer recording of the heart rhythm. None of the testing is inv ...
Arrhythmias - Modest Mango
Arrhythmias - Modest Mango

... Usually due to MI scarring causing an aberrant focal automaticity or a reentrant pathway like flutter ...
Circulatory system
Circulatory system

... Less force is required to pump blood into the pulmonary trunk than into the aortic trunk. ...
Cardiac Asystole and Bradycardia as a Manifestation of Left
Cardiac Asystole and Bradycardia as a Manifestation of Left

... fainting spells. Results of physical and neurologic examinations, electrocardiography, echocardiography, Holter monitoring, and tilt-table testing were normal. Magnetic resonance imaging of the brain showed extensive encephalomalacia of the left frontal lobe. During monitoring, he was aroused from s ...
Cardiac glycosides, antiarrhymic and antianginal drugs
Cardiac glycosides, antiarrhymic and antianginal drugs

... • They have been used to treat heart disorders for over 2000 years, and were the mainstay of heart failure treatment until the discovery of the ACE inhibitors ...
Skills Lab # 5: Notes - LSU School of Medicine
Skills Lab # 5: Notes - LSU School of Medicine

... vascular bed and measure the saturation via a probe. Probe placements include: thumb, finger, bridge of nose, ear and for children the foot and hand. No calibration is required for the equipment. Pulse oximeters have been helpful in reducing the number of arterial blood gases (ABG’s). They are also ...
Alleviating Congestive Heart Failure with Coenzyme Q10
Alleviating Congestive Heart Failure with Coenzyme Q10

... treatment of heart failure. Over the course of 25 years, it has become clear that maximum improvement in heart function will not occur unless plasma levels are greater than 3.5 micrograms per milliliter (mcg/mL). By 2006, there were a total of 22 randomized, controlled trials involving a total of 1, ...
Winter 2015 - Baptist Health South Florida
Winter 2015 - Baptist Health South Florida

... main objective of the trial. It’s also a non-inferiority study, meaning researchers at the Institute hope to show that the device is as good as, if not better than, commercially available pacemakers. The retrievable device is designed to last at least seven years. Retrieval, if any, will depend in p ...
Anterior & Posterior View
Anterior & Posterior View

... "pacemaker" of the heart because it initiates cardiac muscle contraction and determines the heart rate. It is supplied by the sinus node artery, usually a branch of the right coronary artery.  Contraction spreads through the atrial wall until it reaches the Atrio-ventricular (AV) Node in the right ...
Angina Pectoris File
Angina Pectoris File

... Angina pectoris is a clinical syndrome usually characterized by episodes or paroxysms of pain or pressure in the anterior chest.  The cause is insufficient coronary blood flow, resulting in a decreased oxygen supply when there is increased myocardial demand for oxygen in response to physical exerti ...
Restrictive Cardiomyopathy in Cats
Restrictive Cardiomyopathy in Cats

... Just as the echocardiographic appearance of RCM varies between affected cats, so does the long-term prognosis. The presence of congestive heart failure does worsen overall prognosis, although many cats respond very well to medical therapy for some period of time. In the absence of heart failure at t ...
Between Scylla and Charybdis: a choice between
Between Scylla and Charybdis: a choice between

... failure when atrial arrhythmias are present are the loss of an effective, well-timed atrial contraction and the fast and irregular ventricular response. These factors impair diastolic function and finally may lead to tachycardiomyopathy. Although the advantage of a regular ventricular response is imp ...
heart failure - Catholic Medical Partners
heart failure - Catholic Medical Partners

... Heart failure develops over time as the pumping of the heart grows weaker. It can affect the right side of the heart only or both the left and right sides of the heart. Most cases involve both sides of the heart. Right-side heart failure occurs when the heart can’t pump blood to the lungs, where it ...
1 - JACC: Cardiovascular Interventions
1 - JACC: Cardiovascular Interventions

... be less when actually measured. For that reason, 70% has been chosen for multiple studies as a cut point for visually identified stenoses. A problem arises, however, when laboratories are more careful and begin to measure stenotic severity and, therefore, may identify flow-limiting lesions that are ...
Document
Document

... • A number of other studies have also demonstrated that fluctuations in autonomic tone, as measured by HRV, precede the onset of AF • Acetylcholine shortens the atrial refractory period and increases the heterogeneity of atrial refractoriness, effects that predispose to reentry ...
Post MI Hyaluronic Acid to Prevent Remodeling
Post MI Hyaluronic Acid to Prevent Remodeling

... NYHA Class NT-Pro-BNP Labs Healthcare Utilization and Clinical outcomes ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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