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10 New Avenues in Management of Congestive Heart Failure
10 New Avenues in Management of Congestive Heart Failure

... heart failure have known structural heart disease and current or previous symptoms of heart failure. Their symptoms may be classified as NYHA class I, II, III, or IV. Patients with stage D heart failure have refractory symptoms of heart failure at rest despite maximal medical therapy, are hospitaliz ...
Definition of Living Care Plus Coverage
Definition of Living Care Plus Coverage

... Early Cardiomyopathy - An impaired function of the heart muscle, unequivocally diagnosed as Cardiomyopathy by a Registered Medical Practitioner who is a cardiologist, and which results in permanent physical impairment to the degree of New York Heart Association classification Class III, or its equiv ...
How do you measure exercise capacity in chronic heart failure?
How do you measure exercise capacity in chronic heart failure?

... In older editions of textbooks of cardiology, chronic heart failure is described as a condition best treated by rest, and even as a relative contraindication to exercise testing. In common with much else we have been taught about heart failure, such as the adverse consequences of beta adrenoceptor b ...
as a PDF
as a PDF

... levels of endotoxin that are found in decompensated heart failure patients [41]. Already back in 1934, Cohn and Steel discussed the possibility of a yet unidentified pyrogen causing the higher temperature [17]. The accuracy and thoughtful interpretation of these old studies is stunning in the light ...
WPW Syndrome – ECG Manifestations
WPW Syndrome – ECG Manifestations

... who do not have symptoms of tachyarrhythmias but only show preexcitation pattern on the ECG should preferably be referred to as having asymptomatic ventricular ...
Triggers of Malignant Hyperthermia
Triggers of Malignant Hyperthermia

... changes and hyperthermia NMS is a self-limiting disorder when the neuroleptics are withdrawn. Recovery time has been estimated at 7-10 days. ...
L1-Contractile mechanism in heart
L1-Contractile mechanism in heart

... Action Potential in Cardiac Muscle What causes the Plateau in the Action Potential? 1. Slow calcium channels: slow to open & remain open for several tenths of a second  Large quantity of calcium ions flow to the interior of the cardiac muscle fiber ...
Lymphoma Presenting as Severe Left Ventricular Systolic
Lymphoma Presenting as Severe Left Ventricular Systolic

... heart. Pericardial effusion is the most common echocardiographic feature. Diffuse myocardial infiltration documented by echocardiography has rarely been described as a presenting feature of this condition,5,6 but it is commonly found post-mortem.7 This was the type of involvement seen in the present ...
Electrocardiographic changes and intracranial pathology
Electrocardiographic changes and intracranial pathology

... Pharmacological therapy involves the use of sympathetic blocking agents. Alpha blockers may be employed to prevent peripheral and cerebral arterial spasm. Beta-adrenergic blockade can be used to prevent or treat ventricular tachyarrhythmias which are produced by excessive sympathetic stimulation. To ...
File
File

... 6e) Atrial systole (atria contracting) & ventricular diastole (ventricles relaxing) Atrial systole causes the remainder of the blood to go through the AV valve to the ventricle. This is due to the fact that atrial pressure exceeds ventricle pressure, so the AV valves are pushed open and blood then ...
DOC (Eng)
DOC (Eng)

... possible to be registered at all. This is undoubtedly accosiated with the mobility of the tumor, its displacement, changing position with respect to the mitral valve. In all patients, significant improvement or complete recovery occurred after the surgery. Myxomas of the left atrium, which we found ...
8867.Emergency Anaesthetic Protocol
8867.Emergency Anaesthetic Protocol

... Blood flow during external cardiac compression is achieved by one of two mechanisms: the ‘cardiac pump’ and ‘thoracic pump’. Cardiac Pump: This is used in animals weighing less than 20kg, or very narrowchested dogs, e.g Greyhound. The aim is to squueze the ventricles by compression of the ribcage ov ...
H5 THE TRANSPORT SYSTEM
H5 THE TRANSPORT SYSTEM

Impact of Severe Tricuspid Regurgitation on Long Term Survival
Impact of Severe Tricuspid Regurgitation on Long Term Survival

... Materials and Methods: Between 2002 and 2012, 358 consecutive patients (mean age of 54.67± 13.25years, 75.5% female) with severe TR based on history and transthoracic echocardiography (TTE) were enrolled. Patients with severe left sided valvular heart disease and congenital heart disease were exclud ...
Advanced Questions on POTS/Dysautonomia
Advanced Questions on POTS/Dysautonomia

...  Association with autonomic system dysfunction—as well as Chiari syndrome—connective tissue around spinal cord may not be holding in the brain contents  One doesn’t cause the other, but there may be a common cause.  EDS Type 3 & 1 (most common) (Ten Recognized Types)  Study: Migraine was much mo ...
Cardiovascular System
Cardiovascular System

...  Pulmonary Circulation – carries deoxygenated ...
The Kidney in Heart Failure
The Kidney in Heart Failure

... volume increases with heart failure and edema, and in 1935 Peters6 noted that “the kidneys react to changes of circulating blood but are indifferent to changes in the volume of body fluids.” Shortly thereafter, it also became clear that in “heart disease there is inadequate translocation of fluid fr ...
Basics of Pacing - St. Joseph Mercy Health System
Basics of Pacing - St. Joseph Mercy Health System

... Effect of pacing for soft indications on mortality and heart failure in the dual chamber and VVI implantable defibrillator (DAVID) trial. Pacing & Clinical Electrophysiology, 31(7), 828-837 Medtronic, (2013). Clinical gudelines and inidcations. Retrieved February 16, 2015 from http://www.medtronic.c ...
Ch. 18 Review Packet File
Ch. 18 Review Packet File

... CPR), press the analyze button on the AED and deliver a shock according to protocol if indicated. Once the shock has been delivered, continue CPR for another five cycles, or if the patient moves, assist with ventilations as needed with high-concentration oxygen. 5. Criteria are when the patient has ...
AV node - ISpatula
AV node - ISpatula

... autorhythmicity. Because heart muscle is autorhythmic, it does not rely on the central nervous system to sustain a lifelong heartbeat. ...
Myocardial diseases
Myocardial diseases

... Enlarged, flabby with dilation of all the chambers Ventricular thickness <, =,> normal Chambers show mural thrombi: source of thromboemboli Functional regurgitation of mitral or tricuspid valves Coronary arteries are free of significant narrowing M/E- non-specific - most muscle cells are hypertrophi ...
Heart: Dilated Cardiomyopathy
Heart: Dilated Cardiomyopathy

... What is the treatment? There are several drugs used to treat dilated cardiomyopathy. Initial stabilization depends upon the use of: Diuretics – These are drugs that stimulate the kidneys to remove excess fluid from the body. Furosemide and spironolactone are the most commonly used diuretics. Angiote ...
Principles of Vectorial Analysis of EKG`s (cont`d)
Principles of Vectorial Analysis of EKG`s (cont`d)

... electrical potential generated can be represented by a vector, with the arrowhead pointing in the positive ...
Management of Arrythmias in Intensive Care Unit - e
Management of Arrythmias in Intensive Care Unit - e

... the development of AF include structural heart disease (70% in Framingham study over 22 year follow up),5 hypertension (50%),5 valvular heart disease (34%)6 and left ventricular hypertrophy. 2 Post-operative AF is common, particularly after cardiac surgery when the incidence is 25-40% with a peak on ...
Cardiac output and Venous Return
Cardiac output and Venous Return

... electrical potential generated can be represented by a vector, with the arrowhead pointing in the positive ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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