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Print this article - Sudan Heart Journal
Print this article - Sudan Heart Journal

... of patients (13). Another study involving 40 Iranian patients conducted at Tehran Heart Center with LBBB and chest pain showed 75% incidence of significant CAD on angiography (14). Other studies from Western countries show varying rates from 44% to 54% (11)( 15). Such varying figures probably reflec ...
Chapter 35: Chest Trauma
Chapter 35: Chest Trauma

... Cardiac tamponade occurs when excessive fluid builds up in the pericardial sac around the heart. The heart becomes compressed and stroke volume is compromised. The treatment of the patient with cardiac tamponade begins by managing the ABCs, ensuring adequate oxygen delivery, and establishing IV acce ...
Chapter07_Detailed_Answers
Chapter07_Detailed_Answers

... c: The amplitude of QRS complexes is higher in the precordial leads than the limb leads. ...
Chronic recurrent ventricular tachycardia
Chronic recurrent ventricular tachycardia

... required. Lignocaine should be avoided when the arrhythmia complicates a prolonged QT interval. In such cases the heart rate should be accelerated by isoprenaline or temporary pacing. The aim, often impossible, is to identify and correct any underlying cardiac fault. Serum potassium concentrations s ...
Hypertrophic Cardiomyopathy (HCM)
Hypertrophic Cardiomyopathy (HCM)

... problems and are not recommended for individuals with HCM. A medical procedure may be needed if the heart muscle becomes too thick or if a rhythm problem is detected. Most people with HCM have a low risk for sudden cardiac death. However, it is important to identify the small number of patients with ...
07_01 - Assessment of Cardiovascular System
07_01 - Assessment of Cardiovascular System

... the history: shortness of breath (SOB), edema of ankles/legs, pain, pulse rate and rhythm; vital signs, signs and symptoms of oxygen deficit.  Location: Heart lies behind and to the left of the sternum. The upper portion or atria (BASE) lies to the back; the ventricles (APEX) points forward, the ap ...
23. HIV and Cardiac Diseases
23. HIV and Cardiac Diseases

... Furthermore, an association between antiretroviral drugs and lipid concentrations, i.e. hypercholesterolemia and hypertriglyceridemia, has been reported (Stocker 1998, Sullivan 1997). These lipid alterations might jeopardize the benefits of antiretroviral therapy by increasing the risk of coronary d ...
this PDF file
this PDF file

... the pre-reperfusion era, beta-blockers were associated with reductions in cardiovascular mortality (IRR=0.87), MI (IRR=0.78), and angina (IRR=0.88), with no difference for sudden death (IRR=0.77), heart failure, cardiogenic shock or stroke (IRR=2.96). In the reperfusion era, beta-blockers were assoc ...
9 Abstract from Emil..
9 Abstract from Emil..

... Six weeks after induction of left ventricular myocardial infarction (MI), 23 male Wistar rats were examined with PC-MRI, in addition to 8 sham-operated animals. PC-MRI was used to measure longitudinal and circumferential strain in the RV free-wall (SLFW and SCFW) and in the intraventricular septum ( ...
Management of patients with chronic heart failure
Management of patients with chronic heart failure

... More recent evidence4 has shown that eplerenone is also effective in patients with milder symptoms of heart failure if they have other high risk features, including age at least 55 years, and left ventricular ejection fraction no more than 30%, (or if >30% to 35% if the QRS duration is > 130 msecs o ...
Episode 72 ACLS Guidelines 2015 Post Arrest Care
Episode 72 ACLS Guidelines 2015 Post Arrest Care

... recurrent VFib or Vfib 'storm'. For all other patients (those without VFib or STEMI), it is unclear which patients should be transferred for PCI. One of our experts suggests that any patient in whom a cardiac cause is suspected and no other cause is apparent should be considered for emergency PCI. A ...
Managing Atrial Fibrillation - Scioto County Medical Society
Managing Atrial Fibrillation - Scioto County Medical Society

... Ohio State University Medical Center Ross Heart Hospital Columbus, Ohio ...
The treatment of heart failure with preserved ejection
The treatment of heart failure with preserved ejection

... As part of the overall Digitalis Investigation Group (DIG) programme, 988 patients with a clinical diagnosis of CHF and an LVEF > 0.45 were randomised to receive placebo (n = 496) or digoxin (n = 492) in an ancillary trial. By comparison, 3403 patients with CHF and a LVEF of ≤0.45 were randomised to ...
Levosimendan in Congenitally Corrected Transposition of the Great
Levosimendan in Congenitally Corrected Transposition of the Great

... respectively [13]. Excessive right ventricular hypertrophy increases myocardial oxygen requirements that cannot be met by the right coronary system. Hence, the RV perfusion is impaired leading to myocardial fibrosis and reduced coronary flow reserve [2] which may additionally account for a limited b ...
VANDERBILT HEART AND VASCULAR INSTITUTE
VANDERBILT HEART AND VASCULAR INSTITUTE

... It has been 50 years since the first human heart transplant and the first mechanical device was implanted as a bridge to heart transplant. Since that time we have seen these remarkable achievements of the 20th century become integrated into 21st century management of the advanced heart failure patie ...
Preoperative Evaluation and Management of Cardiac Patients
Preoperative Evaluation and Management of Cardiac Patients

... Routine stress imaging in asymptomatic patients is poor at identifying patients who will have adverse outcomes Preoperative revascularization does not affect outcomes ...
Effets du RAAS sur l`AF
Effets du RAAS sur l`AF

... atrial ERP) and induced AF duration (>1000 sec with placebo vs 40 sec with statin)*  Tachy-pacing downregulated L-type calcium channel alpha subunit expression was greatly attenuated by simvastatin.  Retrospective meta-analysis have suggested a beneficial effect in AF in man  Statin therapy has a ...
Anticoagulation in Patients with Dilated Cardiomyopathy, Low
Anticoagulation in Patients with Dilated Cardiomyopathy, Low

... Several prospective randomized trials were either underpowered or had a short period of follow-up. The Heart Failure Long-Term Antithrombotic Study (HELAS) enrolled 197 patients with EF<35% of ischemic and idiopathic etiology, randomized to receive warfarin, aspirin, or placebo; no overall significa ...
electrocardiogram (ecg)
electrocardiogram (ecg)

...  Inverted : young children ,deep inspiration, bundle branch block, ischemia,hypokalemia ...
Use of ACE Inhibitors in Chronic Mitral Regurgitation in Pediatric
Use of ACE Inhibitors in Chronic Mitral Regurgitation in Pediatric

... dimension), LVDS (left ventricular end systolic dimension), LV mass and RF (regurgitation fraction), which are echocardiographic measurements used to assess the degree of MR. Li et al. (2011) was a blinded, randomized controlled trial which evaluated pediatric patients with chronic, moderate to seve ...
Cardiac Output
Cardiac Output

... ejection of blood from the ventricles. Stroke volume is thus inversely proportional to the afterload; that is, an increase in aortic pressure produces a decrease in stroke volume. However, it is noteworthy that afterload is minimized during exercise due to arteriole dilation. This arteriole dilation ...
Tricuspid annular plane systolic excursion and - AJP
Tricuspid annular plane systolic excursion and - AJP

... mortality via hospital and outpatient medical chart review and were followed by the HF program at San Paolo Hospital, Milano, providing a high likelihood that all events were captured. Any death with a cardiac-related diagnosis was considered an event. Cardiac-related mortality was defined as death ...
The new *Silently pressing* DAC, to address the
The new *Silently pressing* DAC, to address the

... Class III ...
NHRD - Guide for Commissioners version 2.indd
NHRD - Guide for Commissioners version 2.indd

... with the aim of simulating more closely the normal hear t function and avoiding the adverse effects of ‘simple ventricular pacing’ such as pacemaker syndrome, promotion of atrial fibrillation and long term deterioration of hear t pump (left ventricular) function. Accordingly, various terms are in co ...
Heart Dysrhythmias Cheat Sheet
Heart Dysrhythmias Cheat Sheet

... Vagal stimulation, Valsalva’s maneuver, carotid sinus massage. Rheumatic carditis due to inflammation involving the SA node. Digoxin toxicity ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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