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Heart Failure
Heart Failure

... keeps track of your heart rate and releases an electric shock if it detects a dangerously fast heart rate, resetting the heart rhythm • Cardiac resynchronization therapy (CRT)— this small device is implanted just below the collarbone. It sends electric signals to the lower chambers of the heart so t ...
mechanisms
mechanisms

... Total Peripheral Resistance • As a consequence of vasodilation in the exercising muscles the total peripheral resistance decreases. • This leads to a – ↓ in diastolic pressure. ...
Cardiac physiology: mechanical events and regulation of cardiac
Cardiac physiology: mechanical events and regulation of cardiac

... o May produce 54 (vibration of ventricle wall due to atrial contraction especially if ventricle is stiff or not compliant [hypertrophy]) - “a” wave of jugular pulse (rise) – due to contraction of atrium - “x descent” fall in atrial pressure – because valve opens - end of phase 1 – LEDV = 120-140 mL ...
Tayler, M., and Ogden, J. (2005) Doctors use
Tayler, M., and Ogden, J. (2005) Doctors use

... would have more serious consequences for their life, that the problem would be more variable over time and that it would last for longer and reported feeling more anxious and depressed than those who received the condition described using the euphemism. GPs are encouraged to be open with their patie ...
Cardiac Cycle - Uplift Education
Cardiac Cycle - Uplift Education

... 1. What are the different valves of the heart? 2. Where are they located? (use #s from diagram) 3. Why is the left ventricle larger than the right ventricle? ...
2HeartPump
2HeartPump

... Right side pumps blood through the lungs Left side through the peripheral organs Each side has an atrium and a ventricle Atrium is a primer pump for the ventricle Ventricle supplies the main pumping force ...
Heart Failure: A Growing Burden
Heart Failure: A Growing Burden

... infiltrative disorder of the heart (Class IIb Level of evidence C) – Used to confirm disorders that may disqualify a patient for transplant (amyloidosis) or identify giant-cell myocarditis which due to rapid progression and poor response to therapy mandates immediate transplantation. – Routine evalu ...
Top 10 Myths of Electrical Injury
Top 10 Myths of Electrical Injury

... • Electrical current may cause injuries distant from its apparent pathway through the victim. • Controversies exist regarding indications for admission and cardiac monitoring following low voltage injuries. ...
door to needle time of streptokinase and st segment resolution
door to needle time of streptokinase and st segment resolution

... therapy predicts short- and long-term outcomes in patients with an Acute Myocardial Infarction (AMI). Methods: The duration of quasi experimental study was 3 years, from July 2006 to June 2009, conducted at Karachi Institute of Heart Diseases. Total 1,023 patients of STEMI treated with streptokinase ...
Cardiac Function in 5-Year Survivors of Childhood CancerA Long
Cardiac Function in 5-Year Survivors of Childhood CancerA Long

... an echocardiogram did not differ or did not differ substantially by cumulative anthracycline dose, age at diagnosis, sex, cardiac irradiation, cumulative cyclophosphamide or ifosfamide dose, time since diagnosis, and tumor diagnoses. Six CCSs died after the first cardiac assessment owing to causes o ...
Should Women Receive Left Ventricular Assist Device Support?
Should Women Receive Left Ventricular Assist Device Support?

EKG - Birdville High School
EKG - Birdville High School

... ▪ It has as inherent rate of 60-100 bpm ▪ Step Two: The signal follows natural pathways through both atria. This causes the blood to contract, pushing blood into the ventricles ▪ Step Three: The signal reaches the A-V node. There, the signal pauses very briefly to give the ventricles time to fill wi ...
Intra-aortic Balloon Counterpulsation: Indications and pitfalls
Intra-aortic Balloon Counterpulsation: Indications and pitfalls

... American Heart Association as well as the European Society of Cardiology for IABP  utilization in STEMI (ST‐Segment Elevation Myocardial Infarction), there is a  growing body of literature that shows no efficacy benefit.   The lack of active cardiac  support, and the need to have some level of resid ...
IABP
IABP

... No change in LVEF at follow-up Stroke rate by 2% (p=0.03) Bleeding by 6% ...
Case 3 A 50-year-old man presenting with palpitations
Case 3 A 50-year-old man presenting with palpitations

... Restoration of sinus rhythm (‘rhythm control’) is usually considered the ‘gold standard’ treatment for atrial fibrillation. However, this is not always possible and even where it is achieved, the effect may be only temporary; a large proportion of patients will have reverted back into AF within 1 ye ...
The structure and function of the heart File
The structure and function of the heart File

... Each heart beat lasts for approximately 0.8 seconds at rest The sequence of events taking place during one complete heartbeat is called the cardiac cycle A single heartbeat is divided into two major phases known as systole and diastole Systole describes periods when the heart is contracting and Dias ...
Familial Incidence of Atrial Septal Defect
Familial Incidence of Atrial Septal Defect

... represent the largest sibship with isolated ASD reported to date. Familial aggregation of ASD has been found in single generatioas, and some kindreds have been traced through several generations. Inheritance follows the multifactorial mode primarily but in certain families autosomal dominant transmi ...
Familial Incidence of Atrial Septal Defect
Familial Incidence of Atrial Septal Defect

... represent the largest sibship with isolated ASD reported to date. Familial aggregation of ASD has been found in single generatioas, and some kindreds have been traced through several generations. Inheritance follows the multifactorial mode primarily but in certain families autosomal dominant transmi ...
Prevalence of myocardial infarction in congestive heart failure
Prevalence of myocardial infarction in congestive heart failure

... Systolic Blood Pressure averaged 128.53 ± 23.88mmHg, while Diastolic Blood Pressure averaged 76.79 ± 17.29 mmHg for patients with controlled blood pressure criteria. Patients with diabetes or renal disease with blood pressure controlled favorably had scores less than 130/80 mmHg while patients with ...
Coronary Heart Disease
Coronary Heart Disease

... adding imaging techniques: Myocardial perfusion scintigraphy or echocardiographysee lecture on cardiac testing. ...
Heart failure with preserved ejection fraction: Clinical
Heart failure with preserved ejection fraction: Clinical

... blocker 40%, ACE inhibitor 25%, spironolactone 15% and digoxin 14%. Conclusions: Patients in I-PRESERVE are broadly representative of those seen in epidemiological studies and, because of this, the results of this trial should be generally applicable to “real world” patients with heart failure and p ...
Cardiac Disease in Pregnancy
Cardiac Disease in Pregnancy

... Aortic valve <1.5cm2 Gradient of >30mmHg ...
Slide 1
Slide 1

... and/or related components are not assigned by the AMA, are not part of CPT®, and the AMA is not recommending their use. The AMA does not directly or indirectly practice medicine or dispense medical services. The AMA assumes no liability for data contained or not contained herein. CPT® is a registere ...
Table 2. Outcomes for QOL Constructs and Exercise Tolerance µ
Table 2. Outcomes for QOL Constructs and Exercise Tolerance µ

... few studies are available comparing outcomes of individuals with CHF and post CABG following a cardiac rehabilitation program. However, one observational study similar to ours in sample size and study design found equal improvements between individuals with and without left ventricular dysfunction i ...
Cardiomyocyte Hypertrophy, Oncosis, and Autophagic
Cardiomyocyte Hypertrophy, Oncosis, and Autophagic

... Interstitial fibrosis was expressed as the percent of Picrosirius red–positive areas respective to the whole area of the EMB sample, excluding the endocardium, scanned using the same digital analysis system. Investigation of apoptosis, oncosis, and autophagy. Tissue sections were rehydrated and incu ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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