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Is there a role for cardioversion in the management of atrial fibrillation?
Is there a role for cardioversion in the management of atrial fibrillation?

... the investigators, the primary outcome – mortality – was worse (though not statistically) in the rhythm-control group, as were secondary outcomes, such as hospitalization and serious arrhythmias. Certainly cardioversion conferred no benefit to patients. It is important to note that with the AFFIRM t ...
Dynamic Coupling between Ventricular Repolarization Duration and
Dynamic Coupling between Ventricular Repolarization Duration and

... groups, RT-interval duration (MRT T, MRT DC and MRT AC) showed significant dependence on the corresponding cardiac cycle length (Figure 3). Additionally, this relationship shows a strong linear dependence between VRD duration and MRR (r > 0.91). The MRT intragroup comparison between AC and DC phases ...
ТЕМЕО - TEMEO
ТЕМЕО - TEMEO

... On the third day of the medical supervision, during physical activity atrial fibrilation episode was registered with high heart rate. A voice contact with the patient was created and an emergency team was sent to him. The patient was brought to the ICD of MHAT “Dr. Hristo Stambolski” – Kazanlak, fo ...
Downloaded
Downloaded

... The calculated peripheral vascular resistance decreased whenever the cardiac output rose during exercise. Only in studies No. 23 and No. 28B, where the cardiac output did not increase, did peripheral resistance also fail to increase. After the exercise period, each subject was carefully questioned c ...
Sample of final exam - Philadelphia University Jordan
Sample of final exam - Philadelphia University Jordan

... A 71-years old male is admitted to your unit with shortness of breath, orthopnea, and progressive reduction in exercise tolerance. His lungs sounds demonstrate crackles in most of his posterior lobes. A pulse oximeter indicates a value of 89%. The following data are available: Blood pressure: 118/7 ...
Use of frog ventricle to examine mechanical and electrical activity of
Use of frog ventricle to examine mechanical and electrical activity of

... polygraph tracings of a series of five measurements, each made in the steady state. Note that, as the reservoir height is increased, ventricular diastolic pressure, systolic pressure, and the rate of pressure rise during systole (dP/dt) all increased as shown graphically in Fig. 5. The increase in s ...
Julie Hutsick, 2011. Heart Failure.
Julie Hutsick, 2011. Heart Failure.

... Stages and Classes of Heart Failure Guidelines for diagnosing and treating Heart Failure have been developed by the American College of Cardiology and The American Heart Association There are four stages, A-D. Stages A and B are patients are risk for Heart Failure and stages C and D are patients wh ...
Rupture of the Interventricular Septum In 1847 Lathem first
Rupture of the Interventricular Septum In 1847 Lathem first

... and the chordal mechnism is intact or only one head is ruptured and there is anular dilation reparative techniques and anuloplasty with or without use of an anoloplasty ring are preferable to valve ...
Left pericardial agenesis in a patient with sinus venosus type atrial
Left pericardial agenesis in a patient with sinus venosus type atrial

... herniation of cardiac structures and any additional defects (7,8). Video assisted thoracoscopy can also be helpful. Congenital pericardial defects are usually isolated, but other congenital anomalies of heart and lung maybe seen in approximately one third of these patients (2). In this case, we pres ...
Ivabradine in Stable Coronary Artery Disease without Clinical Heart
Ivabradine in Stable Coronary Artery Disease without Clinical Heart

... The mean study-drug dose throughout the trial was 8.2±1.7 mg twice daily in the ivabradine group and 9.5±0.9 mg twice daily in the placebo group. At 3 months, the mean heart rate was reduced to 60.7±9.0 beats per minute with ivabradine and to 70.6±10.1 beats per minute with placebo (Fig. S2 in the S ...
Adverse Effects of Combination Angiotensin II Receptor Blockers
Adverse Effects of Combination Angiotensin II Receptor Blockers

... searched for eligible RCTs that included 500 or more subjects, had a follow-up of 3 months or longer, and reported adverse effects. We used a random effects model to calculate the relative risk (RR) and 95% confidence interval (CI) for the following outcome measures: medication discontinuations beca ...
Lecture 16 - Rice University
Lecture 16 - Rice University

... IABP gains wide acceptance as temporary cardiac assist system Cyclosporine, an anti-rejection drug, makes human heart transplants feasible PTCA to treat coronary artery disease with a balloon catheter External & implantable ventricular assist devices enter clinical trials ...
INTRODUCTION - JACC: Heart Failure
INTRODUCTION - JACC: Heart Failure

... models whereas peak VO2 is not.(3,36,37) In 508 HFrEF patients, Sun et al.(37) found that when EOV was observed along with an elevated VE/VCO2 slope, the odds ratio for 6-month mortality increased 4-fold. A CPET score utilizing VE/VCO2 slope ≥34 (7 points), HR recovery ≤6 bpm (5 points), OUES ≤1.4 ...
Acute Heart Failure Risk Stratification: Can We Define Low Risk?
Acute Heart Failure Risk Stratification: Can We Define Low Risk?

... the assessment and treatment of patients who have acute coronary syndrome (Table 1), the emergency physician’s diagnostic tools for heart failure have remained limited, and the complexity of the syndrome itself has led to risk-averse practice styles with extremely high admission rates. Moreover, the ...
Patient information sheet – Ablation of arrhythmias
Patient information sheet – Ablation of arrhythmias

... 2. Atypical atrial flutter is a short circuit affecting a large part of the atrium, but unlike typical flutter which occurs in a very specific location, atypical flutter can involve either the left or the right atrium. It most commonly occurs in patients who have had previous heart operations, previ ...
The Heart
The Heart

... back pressure to function normally • Aortic and Mitral valves are the most commonly repaired or replaced valves • 2 types of valves used – tissue valves from pigs; do not need to take blood thinners – mechanical valves; need to take blood thinners for life ...
svhs advanced biology cardiovascular system
svhs advanced biology cardiovascular system

... 7) Describe the role of the SA node, AV node, bundle of His, and the Purkinje fibers in creating a rhythmic contraction of the heart. 8) Describe what is represented by the P, QRS, and T waves of an EKG. Be able to recognize an abnormal EKG and explain what the print out represents. (Lab) 9) Describ ...
Question 1
Question 1

... However note that someone with 'diastolic heart failure' may have a normal EF. The term 'diastolic heart failure' is an old term which has now been replaced by 'Heart Failure with preserved systolic function' (or 'HFPSF') which represents impaired filling of the LV in response to a volume load despi ...
Infective endocarditis - Oxford Academic
Infective endocarditis - Oxford Academic

... bactericidal activity (i.e. complement), which facilitates the adhesion and formation of vegetations. However, there is no evidence that bacteraemia associated with invasive or semi-invasive interventions is more significant than that after teeth brushing, for example, and other patient risk factors ...
The Cardiac Cycle
The Cardiac Cycle

... Murmur- condition in which one of the valves is not functioning properly (could be an AV or semilunar valves) and blood can flow backwards/inefficiently through the heart. ...
Right Ventricular Pacing-Induced Heart Failure after Mitral Valve
Right Ventricular Pacing-Induced Heart Failure after Mitral Valve

... Meng-Ta Tsai,1 Wei-Chuan Tsai,2 Jun-Neng Roan1 and Chwan-Yau Luo1,3 ...
ENHANCE Trial
ENHANCE Trial

... ♦ ↓ LDL with statins is beneficial, but benefit/risk of LDL reduction with ezetimibe is unknown. Note: Torcetrapib did ↓ LDL & ↑HDL but ↑ mortality in phase III trials. ♦ Combinations further lower LDL, but cardiovascular outcome benefit cannot be assumed (eg. statins with either fibrates or ezetimi ...
Frothy pink sputum with left sided heart failure
Frothy pink sputum with left sided heart failure

... master dom top. 293 Roberts theorized that involving taking up to if appropriate services can. 54 commentaire ...
Heart Failure
Heart Failure

... keeps track of your heart rate and releases an electric shock if it detects a dangerously fast heart rate, resetting the heart rhythm • Cardiac resynchronization therapy (CRT)— this small device is implanted just below the collarbone. It sends electric signals to the lower chambers of the heart so t ...
mechanisms
mechanisms

... Total Peripheral Resistance • As a consequence of vasodilation in the exercising muscles the total peripheral resistance decreases. • This leads to a – ↓ in diastolic pressure. ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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