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... left ventricle starts to contract. At a normal resting heart rate, diastole occupies about two thirds of the entire cardiac cycle, but as the heart rate increases, diastole shortens proportionally more than systole. This explains why preventing tachycardia is an important therapeutic goal. Several f ...
ECG Diagnosis Atrial fibrillation (AF)
ECG Diagnosis Atrial fibrillation (AF)

... Rates: 120-250BPM Median age: 32+/-18 P waves often buried within QRS complex Inverted P waves in leads I, II, III and aVF Pseudo-r’ waves in V1 ...
cardiomyopathy - WordPress.com
cardiomyopathy - WordPress.com

... – Cardiac MRI – Coronary angiography – should be done in all cases to exclude coronary artery disease. ...
Heart rate variability in myocardial infarction and heart failure
Heart rate variability in myocardial infarction and heart failure

... 0167-5273/$ - see front matter © 2007 Elsevier Ireland Ltd. All rights reserved. doi:10.1016/j.ijcard.2006.11.221 ...
Managing low cardiac output syndrome after congenital heart surgery
Managing low cardiac output syndrome after congenital heart surgery

... of blood through the pulmonary circulation, without benefit of a pulmonary ventricle. If an atrial septal communication or fenestration is left at the time of the Fontan procedure, the resulting right-toleft shunt helps to preserve cardiac output. These children have fewer postoperative complication ...
Who Discovered the Frank-Starling Mechanism?
Who Discovered the Frank-Starling Mechanism?

... with a greatly increased force, thereby automatically pumping the extra blood into the arteries. (6) In this review, I will show that neither Otto Frank nor Ernest H. Starling made the first observations on the effect of filling pressure on heart function. I will present evidence that the essential ...
Title
Title

... Caution: Use of CRT devices for AV block and systolic dysfunction patients without ventricular dyssynchrony is not an approved use in the United States. ...
Assessment and consequences of the constant-volume - AJP
Assessment and consequences of the constant-volume - AJP

... roots of the aorta and pulmonary artery, remains constant throughout the cardiac cycle. The constant-volume heart concept was first proposed in 1932 by Hamilton and Rompf (8), who invoked teleological arguments. In the 1980s, Hoffman and Ritman (12, 13) performed a series of pioneering experiments u ...
For Immediate Release Valtech`s Cardioband® Receives CE Mark
For Immediate Release Valtech`s Cardioband® Receives CE Mark

... medical community. We are confident that Cardioband will prove to be a meaningful addition to physician’s available treatment options in addressing MR, providing a first-line mitral valve repair ...
Early Results of Mitral Valve Repair in Patients with Left Ventricular
Early Results of Mitral Valve Repair in Patients with Left Ventricular

... with depressed LV function. Patients with preserved left ventricular EF was considered as control group. Although the sample size of both group was relatively small there is a clear evidence that mitral valve repair is associated with an early decrease of LV volumes in patients with LV dysfunction. ...
Right Ventricular Outflow Tract (RVOT) Ventricular Tachycardia (VT
Right Ventricular Outflow Tract (RVOT) Ventricular Tachycardia (VT

... digoxin, and quinidine, have been extensively tested during pregnancy and have been proven safe. For the ventricular tachycardia in pregnancy, if hemodynamics is stable and therapy is necessary, β-blockers are the drug of choice. If at any time VT becomes unstable or if there is evidence of fetal di ...
Ten-year outcome of enzyme replacement therapy with agalsidase
Ten-year outcome of enzyme replacement therapy with agalsidase

... were not enrolled in the Fabry Registry (figure 1). The median agalsidase beta treatment duration for the 52 patients was 10 years (25th–75th: 7.3–10.3 years). Patient clinical trial data were collected at protocol-specified intervals, whereas Fabry Registry observational data were reported at variabl ...
Delivery Planning for the Fetus with Congenital Heart Disease
Delivery Planning for the Fetus with Congenital Heart Disease

... ♥ The risk of foramen ovale restriction/closure is greater in fetuses with CHD ♥ Foramen ovale restriction/closure in fetuses with CHD can result in distress in-utero or at birth ♥ Fetuses with HRHS and obligate right to left atrial shunting are more likely to develop hydrops fetalis ♥ Serial evalua ...
Vassalos, A. and Lilley, S. and Young, D. and Peng, E. and
Vassalos, A. and Lilley, S. and Young, D. and Peng, E. and

... also shown LV systolic velocities may predict survival in patients with congestive heart failure w11x. Ultimately it may be that LV systolic TDI parameters will have a predictive value in determining postoperative course and can be factored into optimising the timing of surgery. In the current study ...
Sheet #3 / Rawan Al-Majali
Sheet #3 / Rawan Al-Majali

... Cardiogenic shock other causes: electrolytes imbalances, arrhythmias, atrial fibrillations, and decreased contractility and cardiac output. Our aim in patients with pump failure is to reach an acceptable left ventricular end systolic pressure, and to give a sufficient peripheral oxygenation with acc ...
children with congenital heart disease Perioperative manipulation of
children with congenital heart disease Perioperative manipulation of

... There are a number of common causes of reduced oxygen delivery early after cardiac surgery. In general the clinical manifestations of these are similar, but their treatment may be very different. Good intensive care of cardiac patients requires a pre-emptive approach which is tailored for the indivi ...
PFO Patient Brochure
PFO Patient Brochure

... W. L. Gore & Associates has spent more than three decades making products for nearly every field of medicine, often using technology to advance the way procedures are performed. Today, more than 35 million Gore medical devices have been implanted worldwide. ...
management of RHD - Rheumatic Heart Disease Australia
management of RHD - Rheumatic Heart Disease Australia

... to left ventricular inflow develops, due to fibrosis and partial fusion of the mitral valve leaflets • aortic regurgitation, where left ventricular volume overload occurs, and there is an increase in left ventricular end-diastolic volume, eventually leading to left ventricular contractile dysfuncti ...
relationship of echocardiographic geometry of left ventricular
relationship of echocardiographic geometry of left ventricular

... LL Diaz , HB Calleja, GB Rogelio Heart Institute - St. Luke's Medical Center, Quezon City, Philippines This study aimed to search for the ECG characteristics of echocardiographic concentric and eccentric left ventricular hypertrophy (LVH) . The echocardiographic geometry of LVH in patients with card ...
finger pulse rate measurement using a low-cost microcontroller
finger pulse rate measurement using a low-cost microcontroller

... than less active people. Babies have a much higher heart rate at around 120 bpm, while older children have heart rates at around 90 bpm. The heart rate rises gradually during exercises [2] and returns slowly to the rest value after exercise. The rate when the pulse returns to normal is an indication ...
Definition: An extra abnormal heart sound usually detected while
Definition: An extra abnormal heart sound usually detected while

... Unrepaired cyanotic CHD, including palliative shunts and conduits Completely repaired congenital heart defect with prosthetic material or device(surgical or catheter intervention ) for the first 6 months after the procedure Repaired CHD with residual defects at the site or adjacent to the site of a ...
rhythm
rhythm

... • Usually in a short burst leading to Ventricular Fibrillation. ...
Congenitally Corrected Transposition of the Great Arteries
Congenitally Corrected Transposition of the Great Arteries

... c. Complete heart block (2% with 2% increased risk/year) (1) Unusual position of AV node and His bundle (2) May be precipitated by tricuspid valve or VSD surgery D. Situs abnormalities 1. Common – Dextrocardia 2. Suspect ccTGA if abdominal situs solitus III. Physiology (Alonso-Gonzalez, 2010) A. Asy ...
Case Report Study on the distribution characteristics of affected
Case Report Study on the distribution characteristics of affected

Section 2: Hypertension
Section 2: Hypertension

... Essential components of the treatment and surveillance regimen include a complete health history and physical exam. Affected vessels may be identified through the use of X-ray films, electrocardiography, ultrasonography, nuclear scanning, and angiography. Optimal daily cholesterol intake should not ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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