national audit of cardiac rhythm management devices
... of the main pumping chamber (ventricular tachycardia or fibrillation), requiring a shock to restore the normal rhythm. An ICD is an implantable device that can do this automatically within seconds. Most ICDs can also act as pacemakers, though a new type (subcutaneous ICD) has no leads in the heart a ...
... of the main pumping chamber (ventricular tachycardia or fibrillation), requiring a shock to restore the normal rhythm. An ICD is an implantable device that can do this automatically within seconds. Most ICDs can also act as pacemakers, though a new type (subcutaneous ICD) has no leads in the heart a ...
the s-100b substudy of the glutamics-trial: elevation of s
... subdued because of conflicting results mainly related to contamination from extra-cerebral sources such as fat, muscle, skin and bone marrow. In association with cardiac surgery shed mediastinal blood was found to contain high concentrations of S-100B[16, 17]. However, due to the short biological ha ...
... subdued because of conflicting results mainly related to contamination from extra-cerebral sources such as fat, muscle, skin and bone marrow. In association with cardiac surgery shed mediastinal blood was found to contain high concentrations of S-100B[16, 17]. However, due to the short biological ha ...
The pro-apoptotic serum activity is an heart failure
... of patients with HF induces apoptosis of endothelial cells (EC), we aimed to determine whether the pro-apoptotic activity in the serum may predict prognosis of patients with HF. Methods and results We measured the pro-apoptotic activity in the serum of 48 patients with HF of different aetiology by a ...
... of patients with HF induces apoptosis of endothelial cells (EC), we aimed to determine whether the pro-apoptotic activity in the serum may predict prognosis of patients with HF. Methods and results We measured the pro-apoptotic activity in the serum of 48 patients with HF of different aetiology by a ...
Left Ventricular Systolic Longitudinal Function, Afterload and
... Background: In patients with severe aortic stenosis (AS), left ventricular systolic longitudinal function (SLF) is impaired despite preserved ejection fraction (EF). However, similarly to other shortening indexes, SLF depends on afterload and its relationship with contractility has not been thorough ...
... Background: In patients with severe aortic stenosis (AS), left ventricular systolic longitudinal function (SLF) is impaired despite preserved ejection fraction (EF). However, similarly to other shortening indexes, SLF depends on afterload and its relationship with contractility has not been thorough ...
First-in-man Experience of a Novel Transcatheter
... coaptation to reduce tricuspid regurgitation (TR) by occupying the regurgitant orifice area. Objective. To evaluate the feasibility and exploratory efficacy with this transcatheter repair system for the treatment of severe TR. Methods. Seven high-risk patients with severe TR and clinical signs of he ...
... coaptation to reduce tricuspid regurgitation (TR) by occupying the regurgitant orifice area. Objective. To evaluate the feasibility and exploratory efficacy with this transcatheter repair system for the treatment of severe TR. Methods. Seven high-risk patients with severe TR and clinical signs of he ...
2.Heart as Pump - Notes For ANZCA Primary Exam
... o Begins with closure of aorta & pulmon valves (2 heart sound – may be split if aortic closes 1st) o Incursura in aortic pressure waveform produced by closure of valve causing brief backflow of blood o Atrial pressures: LA ~5mmHg; RA ~2mmHg o Ends when vent pressure falls below atrial pressure ⇒ mit ...
... o Begins with closure of aorta & pulmon valves (2 heart sound – may be split if aortic closes 1st) o Incursura in aortic pressure waveform produced by closure of valve causing brief backflow of blood o Atrial pressures: LA ~5mmHg; RA ~2mmHg o Ends when vent pressure falls below atrial pressure ⇒ mit ...
Non-Sustained Ventricular Tachycardia in A Child After Lightning
... nonspecific ST-T wave changes on ECG and minimal echocardiographic abnormalities when he admitted to the pediatric emergency department. Abnormalities on ECG also vary with the type of strike and current of injury. ST elevation and QTc interval prolongation were reported in victims of a direct hit. ...
... nonspecific ST-T wave changes on ECG and minimal echocardiographic abnormalities when he admitted to the pediatric emergency department. Abnormalities on ECG also vary with the type of strike and current of injury. ST elevation and QTc interval prolongation were reported in victims of a direct hit. ...
Percutaneous coronary stenting in patients with left ventricular
... population.1 Coronary revascularisation may be indicated in such patients whenever anginal symptoms, clinical signs or imaging tests suggest viability and the opportunity for improvement of cardiac function.2 However, for these very reasons, subjects with left ventricular dysfunction face major incr ...
... population.1 Coronary revascularisation may be indicated in such patients whenever anginal symptoms, clinical signs or imaging tests suggest viability and the opportunity for improvement of cardiac function.2 However, for these very reasons, subjects with left ventricular dysfunction face major incr ...
Working Group Report Recommendations for driving
... implantable cardioverter-defibrillator (ICD) have an on- the subject of driving for patients with cardiac rhythm going risk of sudden incapacitation that might cause disorders: 'Anyone suffering from disorders of cardiac harm to others while driving a car. Thus, if an ICD rhythm that might, on occas ...
... implantable cardioverter-defibrillator (ICD) have an on- the subject of driving for patients with cardiac rhythm going risk of sudden incapacitation that might cause disorders: 'Anyone suffering from disorders of cardiac harm to others while driving a car. Thus, if an ICD rhythm that might, on occas ...
Understanding cardiac “echo” reports
... each item of interest is considered, and current innovations in each area are noted. ...
... each item of interest is considered, and current innovations in each area are noted. ...
Basic ECG Rhythm Identification Part II Learning Objectives
... • Conduction delay within the right atrium, the AV node, the His-Purkinje system, or a combination of these • Higher prevalence reported in athletes • Prevalence increases with age • Coronary artery disease and angina • Idiopathic degenerative diseases of the conduction system • Drugs: Calcium chann ...
... • Conduction delay within the right atrium, the AV node, the His-Purkinje system, or a combination of these • Higher prevalence reported in athletes • Prevalence increases with age • Coronary artery disease and angina • Idiopathic degenerative diseases of the conduction system • Drugs: Calcium chann ...
MCG
... • The technology material presented in this talk is available for licensing or joint product development. • None of the slides contain any confidential or proprietary information which would prevent patenting the technology. ...
... • The technology material presented in this talk is available for licensing or joint product development. • None of the slides contain any confidential or proprietary information which would prevent patenting the technology. ...
Introduction to Ventricular Assist Device (VAD)
... Patients with chronic heart failure who are not candidates for heart transplantation because of advanced age, kidney disease or chronic obstructive pulmonary disease. Patients who have undergone heart surgery but cannot be weaned from the heart-lung machine. ...
... Patients with chronic heart failure who are not candidates for heart transplantation because of advanced age, kidney disease or chronic obstructive pulmonary disease. Patients who have undergone heart surgery but cannot be weaned from the heart-lung machine. ...
Preload
... understanding function Larger diastolic ventricular volume = More stretch on muscle fibers = greater contraction Frank-Starling mechanism ...
... understanding function Larger diastolic ventricular volume = More stretch on muscle fibers = greater contraction Frank-Starling mechanism ...
diabetes and cardiovascular disease: the road to
... In animal studies, infarct size was linearly related to blood glucose concentration during acute hyperglycaemia and during diabetes, in the presence or absence of preconditioning stimuli. Increases in serum osmolality caused by administration of raffinose did not increase infarct size or interfere w ...
... In animal studies, infarct size was linearly related to blood glucose concentration during acute hyperglycaemia and during diabetes, in the presence or absence of preconditioning stimuli. Increases in serum osmolality caused by administration of raffinose did not increase infarct size or interfere w ...
D evelopment of heart muscle-cell diversity: a
... towards the desired cardiomyocyte subtypes, such as atrial and ventricular muscle cells or cells of the conduction system. It is also important to find out how potential cell-transplantation strategies can be made more efficient, safer and more tailored. In this review we discuss cardiac morphogenes ...
... towards the desired cardiomyocyte subtypes, such as atrial and ventricular muscle cells or cells of the conduction system. It is also important to find out how potential cell-transplantation strategies can be made more efficient, safer and more tailored. In this review we discuss cardiac morphogenes ...
Congenital Heart Disease
... periodic echo-doppler study will confirm closure. Moderate and large VSD: treat HF as in adults; surgical repair once HF improved. – Timing of surgery dependent on severity of shunt, LV function and PAP; closure in early childhood years when PAP remains elevated. – With most VSD’s primary closure or ...
... periodic echo-doppler study will confirm closure. Moderate and large VSD: treat HF as in adults; surgical repair once HF improved. – Timing of surgery dependent on severity of shunt, LV function and PAP; closure in early childhood years when PAP remains elevated. – With most VSD’s primary closure or ...
Atrial Fibrillation and Heart Failure
... are excluded and for this reason there is a lack of clinical studies to guide treatment. It is commonly accepted that the treatment of both paroxysmal and chronic atrial fibrillation requires the optimum treatment of heart failure. Reduction of filling pressure and of neurohormonal stimulation can h ...
... are excluded and for this reason there is a lack of clinical studies to guide treatment. It is commonly accepted that the treatment of both paroxysmal and chronic atrial fibrillation requires the optimum treatment of heart failure. Reduction of filling pressure and of neurohormonal stimulation can h ...
How are arrhythmias managed in the paediatric population in
... interventions, including device implants and catheter ablations, and there is a specialized paediatric centre in 65% of the hospitals. Catheter ablation was very rarely performed in children under 1 year of age, representing only a small proportion (,5%) of the ablation procedures in almost all the ...
... interventions, including device implants and catheter ablations, and there is a specialized paediatric centre in 65% of the hospitals. Catheter ablation was very rarely performed in children under 1 year of age, representing only a small proportion (,5%) of the ablation procedures in almost all the ...
Open full article
... myocardial infarction varies around 5% (ref. 2–3). Most importantly, the majority of these deaths is of arrhythmic origin and about half of them occurs during the first 3 to 6 months of follow up. This provides a background for the concept of risk stratification early after acute myocardial infarcti ...
... myocardial infarction varies around 5% (ref. 2–3). Most importantly, the majority of these deaths is of arrhythmic origin and about half of them occurs during the first 3 to 6 months of follow up. This provides a background for the concept of risk stratification early after acute myocardial infarcti ...
Comparison of the Force-Velocity Relation
... state following any of these interventions, the isovolumic FV relation was again determined, the LVEDP being maintained at a level identical to that during the control period by altering the output of the pump (fig. 1). The ventricular function curve was also determined again at the same mean aortic ...
... state following any of these interventions, the isovolumic FV relation was again determined, the LVEDP being maintained at a level identical to that during the control period by altering the output of the pump (fig. 1). The ventricular function curve was also determined again at the same mean aortic ...
Hypoplastic left heart syndrome
... compared to normal. Even though stage I surgery can now be offered with an early mortality rate of some 15%, parents have to understand fully the implications of embarking on long term palliative care of their newborn child. Survival at 1, 5 and 10 years is some 75%, 70% and 65%, respectively, in th ...
... compared to normal. Even though stage I surgery can now be offered with an early mortality rate of some 15%, parents have to understand fully the implications of embarking on long term palliative care of their newborn child. Survival at 1, 5 and 10 years is some 75%, 70% and 65%, respectively, in th ...
SGD 13 Pacemakers and AICDs revisited READING 1
... electronic device (CIED), several published documents suggest that a magnet can safely be applied to a cardiac pacemaker (PM) to invoke asynchronous pacing or to an implantable cardioverter defibrillator (ICD) to disable antitachycardia therapies.1–3 However, placing a magnet over a PM or ICD can ha ...
... electronic device (CIED), several published documents suggest that a magnet can safely be applied to a cardiac pacemaker (PM) to invoke asynchronous pacing or to an implantable cardioverter defibrillator (ICD) to disable antitachycardia therapies.1–3 However, placing a magnet over a PM or ICD can ha ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.