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left atrial size
left atrial size

... The Mechanical obstruction to flow across the mitral valve results in increased left atrial pressure with a rise in left atrial tension and myocardial oxygen consumption and the enlargement of the atrium is a manifestation of its failure .The increase in wall tension, combined with myocardial cellul ...
Abstract book 2015 - European Society of Cardiology
Abstract book 2015 - European Society of Cardiology

... Congenital heart defects are the most common non-infectious cause of infant mortality. A better understanding of the embryonic development of the mammalian heart is needed to identify the mechanisms underpinning congenital heart defects. One area for investigation is the establishment of left/right ...
Cardiac patients undergoing non
Cardiac patients undergoing non

... Oscarsson, A. British Journal of Anaesthesia 2010 104(3):305-312 ...
Accuracy of Chest Radiography plus Electrocardiogram in
Accuracy of Chest Radiography plus Electrocardiogram in

... Background: Chest radiography and electrocardiogram have been criticized due to their low sensitivity for Left Ventricular Hypertrophy diagnosis compared to echocardiogram. This one, however, is not available in primary health care centers to all hypertensive population. Objective: To evaluate wheth ...
Ventricular Tachycardia Catheter Ablation
Ventricular Tachycardia Catheter Ablation

... To diagnose an arrhythmia, your doctor may ask questions about your past health, perform a physical examination, order blood tests and order other specific tests, depending on the type of arrhythmia suspected. These tests may include:  Echocardiogram (a non-invasive ultrasound image of your heart t ...
The myogenic automatism of the systemic heart of Octopus vulgaris
The myogenic automatism of the systemic heart of Octopus vulgaris

... regions were able to contract regularly when submitted to internal pressure, with a frequency dependent from the pressure value, while the ventricle-aortic region was insensitive to the stretching by internal pressure. This result supports the hypothesis that the automatism in this heart is localize ...
Early Repolarization Is an Independent Predictor of Occurrences of
Early Repolarization Is an Independent Predictor of Occurrences of

... Background—Recent evidence has linked early repolarization (ER) to idiopathic ventricular fibrillation (VF) in patients without structural heart disease. However, no studies have clarified whether or not there is an association between ER and the VF occurrences after the onset of an acute myocardial ...
450 pg/ml - Alberta Heart
450 pg/ml - Alberta Heart

... cardiac death, or arrhythmic event if their EFx is low HF diagnosis may be missed if patient asymptomatic ...
Electroanatomic Mapping System - European Journal of Medical
Electroanatomic Mapping System - European Journal of Medical

... Electroanatomic mapping systems have been introduced into clinical electrophysiology over two decades ago [1-2]. In principle, such systems consist of three different parts: non-fluoroscopic catheter localization, calculation of electrical activation sequences and voltage maps [3-5], 3D display of t ...
Fear of dying and inflammation following acute coronary syndrome
Fear of dying and inflammation following acute coronary syndrome

... stimulation of the vagus nerve inhibits TNFa responses to endotoxins,13 probably through the inhibition of acetylcholine receptors on macrophages.14 Additionally, endotoxin administration depresses HRV in experimental models, and these effects are mimicked by administration of recombinant TNFa.15 Re ...
paced - Weebly
paced - Weebly

... I- What chamber do you want to pace? II- What chamber do you want to sense? III-What do you want to do with the sensed information? Inhibit pacing or trigger pacing? Tracking the Atrial activity ...
Putting a finger on the pulse of today`s and tomorrow`s
Putting a finger on the pulse of today`s and tomorrow`s

...  edicated sub speciality Working Group sessions, with best abstracts presentation. •T  he ESC-BSC joint session presenting the new guidelines on atrial fibrillation, but also the work of the College of Cardiology and the assessment of quality of care in Belgium. ...
Intermittent Complete Atrioventricular Block with Syncope: A Case
Intermittent Complete Atrioventricular Block with Syncope: A Case

... bifascicular block with a markedly prolonged HV interval (greater than or equal to 100 milliseconds) or syncope not proved to be due to AV block and other likely causes have been excluded, specifically ventricular tachycardia. Pacing was not recommended in fascicular block without AV block and sympt ...
Mitral valve implantation using off-pump closed beating intracardiac
Mitral valve implantation using off-pump closed beating intracardiac

... ligation of the LAA. The UCI was used in a chronic study for atrial fibrillation in 17 long-term animals, clinical follow up and autopsy did not document complications associated with the UCI closure or air-embolism. The UCI proved safe, versatile and effective. An approved medical grade UCI is need ...
The analysis of case cohort design in the
The analysis of case cohort design in the

... 7. Therneau TM and Li HZ. Computing the Cox model for case cohort designs. Lifetime Data Analysis 5: 99-112, 1999. 8. Sorensen P and Andersen PK. Competing risks analysis of the casecohort design. Biometrika 87: 49-59, 2000. 9. Crowder MJ. Classical competing risks. London: Chapman and ...
ASSOCIATION OF EARLY REPOLARIZATION WITH RISK OF CARDIAC MORTALITY IN
ASSOCIATION OF EARLY REPOLARIZATION WITH RISK OF CARDIAC MORTALITY IN

... Finally, as acetylcholine or high parasympathetic tone accentuates the manifestation of ER (18), this one is more prevalent among individuals with spinal cord injury at levels of injury that can interrupt central sympathetic control of the heart (at the C5-C6 levels) with high vagal tone and loss of ...
Heart Disease and the Pregnant Patient Vanita Jain, MD FACOG
Heart Disease and the Pregnant Patient Vanita Jain, MD FACOG

... • History of afib/flutter should prompt evaluation for structural disease (baseline echo, screen) • Pharmacologic management should NOT be altered due to pregnancy • If unstable acute arrythmia in pregnancy not responding to medical management can perform electrical cardioversion • Ideally prefer ev ...
Nitric Oxide and Prostaglandins – Important Players
Nitric Oxide and Prostaglandins – Important Players

... physiological, and pathological) played by this peptide, particularly with regard to the cardiovascular system, where the components of the endothelin system are widely expressed, namely in vascular and endocardial endothelium, smooth muscle cells and cardiomyocytes (Brunner et al. 2006). ET-1 acts ...
Experts` recommendations for the management of adult
Experts` recommendations for the management of adult

... The SHOCK trial conducted from April 1993 to November 1998 in 30 centers, and the associated registry assessed the effects of early revascularization (angioplasty or coronary artery-bypass surgery performed in the first 6 h) compared with stabilization by medical treatment in patients hospitalized f ...
Anaesthetist`s evaluation of a child with a heart murmur
Anaesthetist`s evaluation of a child with a heart murmur

... high-risk lesion, such as an AS or HOCM is anticipated, it should be assessed first, while a more benign lesion, such as an atrial septal defect, could be evaluated by a cardiologist after surgery. The type of surgery is also a deciding factor. Any child under one year of age has a much higher risk ...
A Three-Dimensional Functional Assessment of Heart and Vessel
A Three-Dimensional Functional Assessment of Heart and Vessel

... dimensions (http://dir.nichd.nih.gov/lmg/uvo/atlas.html). However, we have presented a technique for measuring both cardiac and vessel size in three dimensions using conventional light microscopy. Not only is this technique less costly, but, more important, it also allows the measurement of cardiova ...
CARDIOVASCULAR PHYSICAL EXAMINATION
CARDIOVASCULAR PHYSICAL EXAMINATION

... Editor’s Note to Readers: For an excellent and more detailed discussion of the cardiovascular physical examination, read Physical Diagnosis Secrets, ed 2, by Salvatore Mangione. 1. What is the meaning of a slow rate of rise of the carotid arterial pulse? A carotid arterial pulse that is reduced (par ...
ATRIAL FIBRILLATION AND CORONARY BYPASS SURGERY
ATRIAL FIBRILLATION AND CORONARY BYPASS SURGERY

... after cardiac surgery. Despite advances in CPB, cardioplegic arrest and surgical techniques, its incidence has paradoxically increased in recent years as the result of surgical patients being older and with more severe illnesses. Many preoperative and postoperative factors have been suggested to inc ...
coronary circulation-anatomy history
coronary circulation-anatomy history

UKRAINIAN MINISTRY OF HEALTH CARE
UKRAINIAN MINISTRY OF HEALTH CARE

... pressure. Usually this requires three separate measurements at least one week apart. Exceptionally, if the elevation is extreme, or end-organ damage is present then the diagnosis may be applied and treatment commenced immediately. Obtaining reliable blood pressure measurements relies on following se ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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