CVS Pathology Lecture Notes (L1)
... NB, don’t need to know vessel changes, just know bengn/malignant Systemic left sided hypertensive heart disease 1. left ventricular hypertrophy without other cause 2. history or pathological evidence of systemic arterial hypertension 3. LV pressure overload LV hypertrophy 4. increased thickness an ...
... NB, don’t need to know vessel changes, just know bengn/malignant Systemic left sided hypertensive heart disease 1. left ventricular hypertrophy without other cause 2. history or pathological evidence of systemic arterial hypertension 3. LV pressure overload LV hypertrophy 4. increased thickness an ...
Takotsubo - S. Blake Wachter, MD, PhD Advanced Heart Failure
... Regionally stunned myocardium results from coronary artery spasm If no observed spontaneous spasm then impaired blood flow is caused by a vulnerable plaque rupture ...
... Regionally stunned myocardium results from coronary artery spasm If no observed spontaneous spasm then impaired blood flow is caused by a vulnerable plaque rupture ...
Congenital Heart Disease - Cleveland Clinic Center for Continuing
... • Larger lesions – Softer Murmurs – LV volume overload and pulmonary hypertension – Most common cause of Eisenmenger syndrome ...
... • Larger lesions – Softer Murmurs – LV volume overload and pulmonary hypertension – Most common cause of Eisenmenger syndrome ...
Paediatric Cardiology - Dr. Herchel Rosenberg
... to Right shunt because of greater compliance of right ventricle Loads right ventricle and right atrium Increased pulmonary blood flow at normal pressure Low resistance ...
... to Right shunt because of greater compliance of right ventricle Loads right ventricle and right atrium Increased pulmonary blood flow at normal pressure Low resistance ...
Jun Summary
... implantation. Understanding these associations may help identify specific risks that can be mitigated to avoid morbidity and mortality, and thereby improve long-term outcomes after LVAD placement. Stulak, et al. examined these findings in a cohort of continuous-flow (CF) LVAD patients implanted at t ...
... implantation. Understanding these associations may help identify specific risks that can be mitigated to avoid morbidity and mortality, and thereby improve long-term outcomes after LVAD placement. Stulak, et al. examined these findings in a cohort of continuous-flow (CF) LVAD patients implanted at t ...
File
... Reduce slow inward current and force of contraction Also slow conduction of AV node due to calcium channel blockade Verapamil used in acute paroxysmal tachycardia ...
... Reduce slow inward current and force of contraction Also slow conduction of AV node due to calcium channel blockade Verapamil used in acute paroxysmal tachycardia ...
Pharm D HF
... Stage A: Patient at high risk for developing HF with no structural disorder of the heart Stage B: Patient with structural disorder without symptoms of HF Stage C: Patient with past or current symptoms of HF associated with underlying structural heart disease Stage D: Patient with end-stage disease w ...
... Stage A: Patient at high risk for developing HF with no structural disorder of the heart Stage B: Patient with structural disorder without symptoms of HF Stage C: Patient with past or current symptoms of HF associated with underlying structural heart disease Stage D: Patient with end-stage disease w ...
AORTIC ANEURYSMS AND DISSECTION Aorta is about 1 inch or 2
... Pericardial Tamponade A. Patho/Causes a. Rate of fluid accumulation, not the amount i. 200 mL of fluid develops rapidly = tamponade ii. 2 L can accum slowly – heart can adapt and stretch b. Pericardial effusion that impairs diastolic filling of the heart c. Pressures of RV, LV, RA, LA, pulm art and ...
... Pericardial Tamponade A. Patho/Causes a. Rate of fluid accumulation, not the amount i. 200 mL of fluid develops rapidly = tamponade ii. 2 L can accum slowly – heart can adapt and stretch b. Pericardial effusion that impairs diastolic filling of the heart c. Pressures of RV, LV, RA, LA, pulm art and ...
Interventional Cardiology
... premature depolarization (VPD)-induced cardiomyopathy is a condition in which frequent ventricular ectopic impulses result in left ventricular (LV) dysfunction leading to systolic heart failure (HF) [1–3] . The causal relationship between VPDs and nonischemic cardiomyopathy (NICM) has been firmly e ...
... premature depolarization (VPD)-induced cardiomyopathy is a condition in which frequent ventricular ectopic impulses result in left ventricular (LV) dysfunction leading to systolic heart failure (HF) [1–3] . The causal relationship between VPDs and nonischemic cardiomyopathy (NICM) has been firmly e ...
Valve Sparing Surgery for Papillary Fibroelastoma of the Aortic Valve
... the papillary surface.5 The matrix consists of proteoglycans, elastic fibers, and rarely spindle cells. The fibrinous matrix is the hallmark of this tumor. Clinically, most CPF are found incidentally at the time of cardiac investigation for unrelated problem, or at autopsy. 3 The most common clinica ...
... the papillary surface.5 The matrix consists of proteoglycans, elastic fibers, and rarely spindle cells. The fibrinous matrix is the hallmark of this tumor. Clinically, most CPF are found incidentally at the time of cardiac investigation for unrelated problem, or at autopsy. 3 The most common clinica ...
Congenital Heart Diseases II
... breathlessness since infancy. He managed well until January of 1894 when dyspnea increased and edema set in. Seven months later he was admitted to the hospital in a state of heart failure……He improved with rest and digitalis, ...
... breathlessness since infancy. He managed well until January of 1894 when dyspnea increased and edema set in. Seven months later he was admitted to the hospital in a state of heart failure……He improved with rest and digitalis, ...
G-0967 Coronary Heart Disease, Myocardial
... Treatment of Angina • Antianginals (nitroglycerin) • Antiplatelets (aspirin) • ACE inhibitors • Beta-blockers • Calcium channel blockers • Thrombolytic therapy (if thrombi are the cause) • Oxygen administration • Percutaneous transluminal coronary angioplasty or coronary artery bypass graft to prev ...
... Treatment of Angina • Antianginals (nitroglycerin) • Antiplatelets (aspirin) • ACE inhibitors • Beta-blockers • Calcium channel blockers • Thrombolytic therapy (if thrombi are the cause) • Oxygen administration • Percutaneous transluminal coronary angioplasty or coronary artery bypass graft to prev ...
Valvular Heart Disease: Review and Update
... the symptoms are more than mild. Compelling evidence supports surgical correction before the onset of permanent left ventricular damage, even in asymptomatic patients.1,3 As in patients with mitral valve regurgitation, timing of surgical intervention correlates with a good outcome. In patients with ...
... the symptoms are more than mild. Compelling evidence supports surgical correction before the onset of permanent left ventricular damage, even in asymptomatic patients.1,3 As in patients with mitral valve regurgitation, timing of surgical intervention correlates with a good outcome. In patients with ...
Levosimendan in Congenitally Corrected Transposition of the Great
... resulted in the reduction of the tricuspid valve regurgitant volume and the resultant decrease in the left atrial volume. Moreover, levosimendan reduced RV filling pressures, leading to functional improvement [14]. Although previous studies have reported beneficial effects of levosimendan on the RV ...
... resulted in the reduction of the tricuspid valve regurgitant volume and the resultant decrease in the left atrial volume. Moreover, levosimendan reduced RV filling pressures, leading to functional improvement [14]. Although previous studies have reported beneficial effects of levosimendan on the RV ...
Ablation of arrhythmias in adult patients after Fontan operation
... lation is performed in drug‑refractory disorders. However, access to pulmonary venous atrium in Fontan patients with lateral tunnel or external conduit is limited. There are a few data regarding RF ablation in adult patient after Fontan opera‑ tion. In this letter, we would like to present our resul ...
... lation is performed in drug‑refractory disorders. However, access to pulmonary venous atrium in Fontan patients with lateral tunnel or external conduit is limited. There are a few data regarding RF ablation in adult patient after Fontan opera‑ tion. In this letter, we would like to present our resul ...
Levosimendan in a neonate with severe coarctation of aorta and low
... anti‑ischemic properties.[5] Furthermore, because of its calcium‑sensitizing properties, levosimendan is an ideal therapeutic for the immature myocardium, characterized by a highly calcium‑dependent contractility.[6,7] The administration of levosimendan in paediatric patients has been described sinc ...
... anti‑ischemic properties.[5] Furthermore, because of its calcium‑sensitizing properties, levosimendan is an ideal therapeutic for the immature myocardium, characterized by a highly calcium‑dependent contractility.[6,7] The administration of levosimendan in paediatric patients has been described sinc ...
Evaluation of Diastolic Dysfunction by Echocardiogram
... Garcia MJ, et al. Color M-mode doppler flow propagation velocity is a preload insensitive index of left ventricular relaxation: animal and human validation. JACC 2000; 35: 201-8. Nagueh SF, et al. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estim ...
... Garcia MJ, et al. Color M-mode doppler flow propagation velocity is a preload insensitive index of left ventricular relaxation: animal and human validation. JACC 2000; 35: 201-8. Nagueh SF, et al. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estim ...
Basic Cardiovascular System and Pathological Abnormalities
... Cardiomegaly, pleural effusions ECG – persistent ST segment elevation with flat or inverted T waves in limb & left lateral limb leads Pericardiocentesis – performed when tamponade physiology present ...
... Cardiomegaly, pleural effusions ECG – persistent ST segment elevation with flat or inverted T waves in limb & left lateral limb leads Pericardiocentesis – performed when tamponade physiology present ...
Cardiac Output and Venous Return
... Construct a vascular function curve. Predict how changes in total peripheral resistance, blood volume, and venous compliance influence this curve. Use the intersection point of the cardiac function curve and vascular function curve to predict how interventions such as hemorrhage, heart failure, auto ...
... Construct a vascular function curve. Predict how changes in total peripheral resistance, blood volume, and venous compliance influence this curve. Use the intersection point of the cardiac function curve and vascular function curve to predict how interventions such as hemorrhage, heart failure, auto ...
Pharmacotherapy of Cardiogenic Shock_Master
... How do patients typically present with cardiogenic shock? Lightheadedness, SOB, chest pain, palpitations, cardiac arrest What are some causes of cardiogenic shock? - Any cause of acute, severe LV or RV dysfunction - MI with LV failure (5-8%STEMI, 2.5% NSTEMI) - Mechanical complications: ventricular ...
... How do patients typically present with cardiogenic shock? Lightheadedness, SOB, chest pain, palpitations, cardiac arrest What are some causes of cardiogenic shock? - Any cause of acute, severe LV or RV dysfunction - MI with LV failure (5-8%STEMI, 2.5% NSTEMI) - Mechanical complications: ventricular ...
Subcutaneous Implantable Cardioverter Difibrillator (SICD
... widely used and studies have shown significant mortality benefit in selected patients at increased risk of SCD. However, the use of ICDs may at times be complicated with the implantation procedure, programing, device malfunction, and lead performance deterioration by time. Traditionally, the ICD is ...
... widely used and studies have shown significant mortality benefit in selected patients at increased risk of SCD. However, the use of ICDs may at times be complicated with the implantation procedure, programing, device malfunction, and lead performance deterioration by time. Traditionally, the ICD is ...
4- Cardiac output, exercise and cardiac hypertrophy
... pericardial effusion affect stroke volume. D--Myocardial contractility: It is the intrinsic ability of the cardiac muscle fibers to develop force at a given muscle length. It can be estimated by the ejection fraction, which is normally 55%. When contractility increases, the ventricle can develop gre ...
... pericardial effusion affect stroke volume. D--Myocardial contractility: It is the intrinsic ability of the cardiac muscle fibers to develop force at a given muscle length. It can be estimated by the ejection fraction, which is normally 55%. When contractility increases, the ventricle can develop gre ...
Heart Murmurs Puppies and Kittens Adult Cats Adult Dogs
... Ultrasound images of the heart will assess chamber sizes and muscle function, as well as measuring the flow of blood through the heart valves. Ultrasound is necessary to identify the type of heart disease present. Ultrasound rarely requires sedation in dogs but cats are often sedated. An ultrasound ...
... Ultrasound images of the heart will assess chamber sizes and muscle function, as well as measuring the flow of blood through the heart valves. Ultrasound is necessary to identify the type of heart disease present. Ultrasound rarely requires sedation in dogs but cats are often sedated. An ultrasound ...
Ablation of right sided ventricular tachycardias
... majority (7/10) of which were found in the right ventricular apex -Female gender and left ventricular dysfunction were independently associated with increased risk for thrombosis in ARVC -During a median FU of 38 months (range 2-128), no thromboembolism event or sudden death was observed in OAC-grou ...
... majority (7/10) of which were found in the right ventricular apex -Female gender and left ventricular dysfunction were independently associated with increased risk for thrombosis in ARVC -During a median FU of 38 months (range 2-128), no thromboembolism event or sudden death was observed in OAC-grou ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.