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Diastolic Dysfunction - UCSF | Department of Medicine
Diastolic Dysfunction - UCSF | Department of Medicine

... Clinical definition: 35-40% of men with CHF, 65-75% of women with CHF o Cardiac dysfunction with normal EF (>50%) or with findings of diastolic dysfunction on echo/cath o Difficulties: timing of echo in relation to treatment, mixed etiologies o Asymptomatic diastolic dysfunction: Mayo Clinic study - ...
Unreliability of M-Mode Left Ventricular Dimensions for Calculating
Unreliability of M-Mode Left Ventricular Dimensions for Calculating

... adults with no objective evidence of cardiac disease. In addition, single-dimension volume measurements have not been validated for other noncardiac patient groups, yet data based on the LVID method continue to be reported for patients with hypertension l7 and muscular dystrophy.18 The purpose of th ...
left-sided_congestive_heart_failure
left-sided_congestive_heart_failure

... Pump (Muscle) Failure of the Left Ventricle  Heart muscle is flabby and weak for unknown causes (so-called “idiopathic dilated cardiomyopathy” or DCM)  Trypanosomiasis (disease caused by the protozoa, Trypanosoma)—rare  Toxicity of doxorubicin (a chemotherapeutic drug) to the heart in dogs  Inad ...
Left-Sided Congestive Heart Failure
Left-Sided Congestive Heart Failure

... Pump (Muscle) Failure of the Left Ventricle  Heart muscle is flabby and weak for unknown causes (so-called “idiopathic dilated cardiomyopathy” or DCM)  Trypanosomiasis (disease caused by the protozoa, Trypanosoma)—rare  Toxicity of doxorubicin (a chemotherapeutic drug) to the heart in dogs  Inad ...
Valvular Heart Disease in Dogs
Valvular Heart Disease in Dogs

... (e.g., Angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, spironolactone) leads to improved survival. The ACE inhibitors have been studied in dogs with CVD, however there is little information available regarding use of beta-blockers or spironolactone. Angiotensin-converting enzyme (ACE) ...
-click here for handouts (full page)
-click here for handouts (full page)

... Angiography grade 3+ to 4+ ...
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没有幻灯片标题

... tendineae papillary muscles(3 group ...
The Heart
The Heart

... During diastole, normal filling of the ventricles increases the volume of each ventricle to about 110 to 120 ml. This volume is called the end-diastolic volume. Then, as the ventricles empty during systole, the volume decreases by about 70 ml, which is called the stroke volume output. The remaining ...
Formation of the Cardiac Loop
Formation of the Cardiac Loop

... 1. Proliferation of mesenchyme in A-V orifice. 2. The cords becomes hollowed out by bloodstream. 3. The muscular tissue degenerates, replaced by dense CNT. 4. A-V valves = CNT covered by endocardium connected to papillary muscles by chordae tendineae. 5. Right = tricuspid valves Left = bicuspid (Mit ...
Global Strain in Severe Aortic Valve Stenosis
Global Strain in Severe Aortic Valve Stenosis

... Horten, Norway) speckle tracking software 2-D. GLS was determined as the magnitude of strain at the aortic valve closure, and systolic strain rate (SRS) was determined as the maximal negative SR value during the ejection phase. Both parameters were assessed in all 3 apical planes, and the mean value ...
Quiz 3 Critical Structures
Quiz 3 Critical Structures

... atrial branch and nodal artery – branch running to R atrium, and splits to SA Node marginal artery – branch running on R margin of R ventricle, w/small cardiac vein posterior interventricular artery – branch running on post. between the ventricles with the middle cardiac vein left coronary artery – ...
The thoracic cavity and heart
The thoracic cavity and heart

... The interventricular septum separates the right from the left ventricle and bulges into the right cavity, making it crescentic in cross section. The walls of the cavity are covered by interlacing muscle bands except superiorly where the smooth-walled wide infundibulum leads to the pulmonary orifice. ...
Noncompaction of the ventricular myocardium mimicking ischemic
Noncompaction of the ventricular myocardium mimicking ischemic

... with diffuse left ventricular hypokinesis without regional wall motion abnormalities, presumably due to ventricular remodeling.2 In these patients with global left ventricular dysfunction, differentiation of INVM from other forms of cardiomyopathy such as dilated cardiomyopathy and ischemic cardiomy ...
Ministernotomy for aortic valve replacement
Ministernotomy for aortic valve replacement

... brought a new concern to the surgeon: How long a skin incision and thoracic opening are necessary to safely carry out cardiac surgical procedures? Minimally invasive approaches to aortic valve surgery have been previously described.1–3 We believe that the approach to aortic valve surgery must avoid ...
Is the heart affected in primary Sjögren`s syndrome? An
Is the heart affected in primary Sjögren`s syndrome? An

... clinical rheumatic and serological findings. Low C4 levels and/or palpable purpura are two characteristics that may classify patients (1 to 5) who are in increased risk for lymphoproliferative disease and death (6). This echocardiographic study aimed to describe the anatomic and functional cardiac di ...
Impact of Severe Tricuspid Regurgitation on Long Term Survival
Impact of Severe Tricuspid Regurgitation on Long Term Survival

... 237 cases (66.2%). 275 cases (76.8%) had pulmonary regurgitation. 81 cases (22.6%) underwent surgical TR repair, and 38.5% experienced significant TR after surgery which were included in the study. Total mortality rate was about 3.3% (12 cases) .The cause of death was right sided heart failure in 6 ...
Pulmonary Hypertension and the Vevo
Pulmonary Hypertension and the Vevo

... velocity (TRV), as it is involved in the calculation of pulmonary vascular resistance (PVR). The images shown below are from a normal mouse and therefore do not show regurgitation. If present it would appear as a strong spike downwards in the spectrum having significant velocity. PVR is used clinica ...
Ventricular ectopic beats in structurally normal heart: When to stop
Ventricular ectopic beats in structurally normal heart: When to stop

... Background and objective: Ventricular ectopic beats (extra systoles, premature beats) are frequently found in healthy people. Ectopic beats in patients without apparent heart disease are more prominent at rest and disappear with exercise. Treatment is not necessary unless the patient is highly sympt ...
Afterload Reduction Therapy for Congestive Heart Failure
Afterload Reduction Therapy for Congestive Heart Failure

... California, School of Medicine , Davis , Ca liforn ia, and Sacramento Medica l Center, Sacramento, California ...
L1- Heart
L1- Heart

... Bounded inferiorly by post part of coronary sulcus , which lodges the ...
CHAPTER 4 CIRCULATION
CHAPTER 4 CIRCULATION

... 5. What effect would this drug have on the upstroke of the action potential and on the propagation velocity of myocardial cells? 6. What effect does this drug have on the action potentials of the automatic cells in the sinoatrial (SA) node and on the action potential of the conduction fibers in the ...
view a sample chapter
view a sample chapter

... For persons older than middle age or who show symptoms or signs of cardiovascular disease, auscultate each carotid artery for the presence of a bruit. This is a blowing, swishing sound indicating blood flow turbulence; normally, there is none. Keep the neck in a neutral position. Lightly apply the b ...
Silesian Center for Heart Diseases
Silesian Center for Heart Diseases

... Lung Transplant Program, offers severely ill patients with chronic lung disease a cure and hope they have been waiting for. Silesian Center for Heart Diseases takes pride in its position as a national leader in minimally invasive (MIDCAB, TECAB) and hybrid (MIDCAB/TECAB +PCI) treatment. Todays patie ...
Atrioventricular Pressure Half-Time
Atrioventricular Pressure Half-Time

... left atrioventricular pressure difference to fall to half its initial value (half-time) varied with the anatomic severity of the valvular stenosis. In mild mitral stenosis, the halftime was approximately 100 msec; in moderate stenosis, it was about 200 msec; and it was 300 msec or longer in severe s ...
Heart ppt File
Heart ppt File

... electrical impulses, they spread rapidly across both atria due to the inter-connecting nature of the cardiac muscle cells When the electrical impulses reach the border between the atria and ventricles they are blocked by a band of nonconducting ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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