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Congenitally Corrected Transposition of the Great Arteries in a
Congenitally Corrected Transposition of the Great Arteries in a

... waves in the right precordial leads that are absent from the left precordial leads. Also, the His bundle is longer as a result of the greater distance between the atrioventricular node and the base of the interventricular septum. This explains the disturbances of atrioventricular conduction that are ...
TEE in Adult Congenital Heart Disease: Indication and Guideline
TEE in Adult Congenital Heart Disease: Indication and Guideline

... LAA, Pulmonary veins, atrial septum, thoracic aorta ...
Function and form in the developing cardiovascular system
Function and form in the developing cardiovascular system

... starts to acquire its autonomic innervation pattern for neural modulation.46 The function of delay generation between the activation of atria and ventricles begins to shift from the slowly conducting myocardium of the atrioventricular canal5,17,36 that is similar to arrangement in the adult hearts o ...
Coronary flow in Aortic Stenosis
Coronary flow in Aortic Stenosis

... We measured the maximal velocity of coronary blood flow in the leftanterior descending coronary artery at the time of elective open-heart surgery in 14 patients with aortic stenosis and LVH (13 had angina) and in 8 controls without LVH. The ratio of peak velocity of coronary blood flow, after a 20-s ...
PDF - Circulation
PDF - Circulation

... There is some week to week variation but this can be partially adjusted for by considering % reduction with two consecutive tests. However, qualification of success with 100% supression would resolve many uncontrolled variables when testing an antiarrhythmic drug. We agree that physiological variabl ...
Dobutamine stress echocardiography: A sensitive indicator of
Dobutamine stress echocardiography: A sensitive indicator of

... From the University of Arizona College of Medicine and Steele Memorial Children's Research Center. Tucson. Arizona. This study was supported ...
Higher Human Biology - Mrs Smith' s Biology
Higher Human Biology - Mrs Smith' s Biology

... • The pacemaker is located in the wall of the right atrium. • The pacemaker is specialised tissue which exhibits spontaneous excitation. • This means that it initiates electrical impulses which make the heart contract at a certain rate. • This rate can then be regulated by other factors to suit the ...
Difficulty Level 2
Difficulty Level 2

... The valve located between the right atria and right ventricle is the __________, and the valve that is located between the left atrium and the left ventricle is____________ a. tricuspid, seminlunar c. aortic semilunar, bicuspid b. bicuspid, tricuspid d. tricuspid, mitral This is also known as the v ...
and idiopathic hypertrophic subaortic stenosis - Heart
and idiopathic hypertrophic subaortic stenosis - Heart

... shorter than in normal subjects. IVCT is a direct expression of the sum of factors comprising contractility, especially the rate of rise of left ventricular pressure, and it also reflects the end-diastolic stretch and end-diastolic volume (Katz and Feil, I923; Reeves et al., I960; Spodick and Kumar, ...
depolarization waves.
depolarization waves.

... The amplitude of the waves is also affected by the electrical resistance of the pathways to the distant electrodes; in addition, as has been already pointed out, the recorded voltages represent only the difference between the influences of simultaneous and opposite electrical dipoles in a complicate ...
- Wiley Online Library
- Wiley Online Library

... with shunts. In two ventricle hearts without a shunt, the adequacy of cardiac output and oxygen delivery and consumption can be ascertained using measured mixed venous saturation, classically from the PA. There is no such point in the body to make measurements in complex CHD. The use of near-infrare ...
RECENT ADVANCES IN SURGICAL AND PERCUTANEOUS
RECENT ADVANCES IN SURGICAL AND PERCUTANEOUS

... Surgical mitral valve (MV) repair has evolved to become the standard of care for severe mitral regurgitation (MR) with superior acute and long-term results compared to valve replacement. Minimally-invasive surgical techniques have been successful in reducing operative trauma while yielding equivalen ...
Lecture 8 - Harper College
Lecture 8 - Harper College

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American College of Radiology End User License Agreement
American College of Radiology End User License Agreement

... etiology of the illness. Early and accurate detection and characterization of myocardial disease therefore becomes critical for appropriate patient treatment and management and to potentially avoid disease progression. Nonischemic CM is more common in women and younger individuals. In general, the p ...
Physiologic Determinants of Mitral Inflow Pattern Using a Computer
Physiologic Determinants of Mitral Inflow Pattern Using a Computer

... Department of Medicine, Columbia University Medical Center, New York, New York, †Department of Anesthesiology, Columbia University Medical Center, New York, New York, and ‡Columbia Center for New Media Teaching and Learning (CCNMTL), New York, New York Background: Although echo Doppler recordings of ...
Revista Imágenes 07
Revista Imágenes 07

... affecting the cardiovascular system. We will briefly discuss the technique of Cardiac MRI (or CMR) showing an iconographic presentation of image findings in studies performed in our department. There are two basic sequences, namely: sequence of "dark blood" or spin echo, and sequence of "bright bloo ...
Predictors of Increased Left Ventricular Filling Pressure in Dialysis
Predictors of Increased Left Ventricular Filling Pressure in Dialysis

... Several previous studies have shown that heart failure is a common finding in end-stage renal failure patients (25), due to existence of various cardiovascular disorders in these patients (1,2). The E/E’ ratio has been shown to be the best correlate of LV filling pressure (10) in heart failure patie ...
A case of single ventricular heart, pulmonary atresia, patent ductus
A case of single ventricular heart, pulmonary atresia, patent ductus

... pulmonary atresia and ventricular septal defects, they pose a unique and challenging problem at the time of surgical repair. Such repairs involve the closure of ventricular septal defect, relief of right ventricular outflow tract obstruction, maintenance of pulmonary valve competency when possible, ...
05_Instrumental methods of examination of cardiovascular system
05_Instrumental methods of examination of cardiovascular system

... and end abruptly and usually last several hours. The heart rate may be 140-240/min(usually 170-220/min) and is perfectly regular, therate will not vary more than 1-2 beats per minute.Exercise, change of position, breath-holding, carotid sinus massage, or induced gagging or vomiting either has no eff ...
Longitudinally and circumferentially directed movements of the left
Longitudinally and circumferentially directed movements of the left

... radius of curvature and greater moment of torque. As such, they are likely to dominate the direction of circumferential motion. This is supported by work from Taber et al. who showed that, due to a larger moment arm, the outer layers have a mechanical advantage relative to the inner layers [20]. On ...
Pedunculated Giant Left Atrial Mass: tumor or thrombus?
Pedunculated Giant Left Atrial Mass: tumor or thrombus?

... heparin prevented her undergoing surgery. ...
Ventricular Arterial Stiffening
Ventricular Arterial Stiffening

... loops) is also somewhat steeper. As reported by Chen et al,5 Ea, Ees, and diastolic stiffness increase with age and correlate with one another. Figure 1C shows such an inverse relation between Ees and total arterial compliance, with the latter a component of Ea (Ea increases as compliance declines). ...
Evaluation of the Right Ventricular Function in Hypertrophic
Evaluation of the Right Ventricular Function in Hypertrophic

... myocardial hypertrophy of the left ventricle (LV) (Elliott et al. 2008). Tissue Doppler imaging (TDI), strain and strain rate (SR) imaging are relatively newly developed echocardiographic techniques that allow a better assessment of regional myocardial function. Several studies have suggested that T ...
Impact of Cardiac Resynchronization Therapy Using
Impact of Cardiac Resynchronization Therapy Using

... Aachen, Essen and Magdeburg, Germany; Utrecht, The Netherlands; Brussels, Belgium; and St. Paul, Minnesota We sought to investigate the impact of six months of cardiac resynchronization therapy (CRT) on echocardiographic variables of left ventricular (LV) function. BACKGROUND Cardiac resynchronizati ...
Transcatheter Aortic Valve Implantation (TAVI/R) for Severe Aortic
Transcatheter Aortic Valve Implantation (TAVI/R) for Severe Aortic

... • A Symptomatic severe calcific Aortic Stenosis [trileaflet] who have aortic and vascular anatomy suitable for TAVR and a predicted survival >12 months, and who have a prohibitive surgical risk as defined by an estimated 50% or greater risk of mortality or irreversible morbidity at 30 days or other ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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