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... or at a submaximal oxygen consumption value of 15 ml/kg per min, or to the increase in pulmonary capillary wedge pressure from rest to peak exercise. We therefore conclude that, in the patients studied, left atria1 pressure was not a major determinant of exercise capacity. Do these findings apply to ...
... or at a submaximal oxygen consumption value of 15 ml/kg per min, or to the increase in pulmonary capillary wedge pressure from rest to peak exercise. We therefore conclude that, in the patients studied, left atria1 pressure was not a major determinant of exercise capacity. Do these findings apply to ...
Reply to “Letter to the editor: `The role of short QT - AJP
... the potential role of reduced cytosolic ATP (derived from glucose and glycogen) in explaining shortening of the QT interval (through activation of the ATP-sensitive K⫹ channel) as well as elevations in end-diastolic pressure (through reduced sarcoplasmic reticulum Ca2⫹ uptake and increased cytosolic ...
... the potential role of reduced cytosolic ATP (derived from glucose and glycogen) in explaining shortening of the QT interval (through activation of the ATP-sensitive K⫹ channel) as well as elevations in end-diastolic pressure (through reduced sarcoplasmic reticulum Ca2⫹ uptake and increased cytosolic ...
Sudden cardiac death
... hemodynamic compromise that may produce a cardiovascular collapse can occur during any rapid supraventricular tachycardia in these patients. In young athletes under 35, sudden death occurs fundamentally in patients with cardiomyopathy, usually, but not exclusively, of the hypertrophic variety. In co ...
... hemodynamic compromise that may produce a cardiovascular collapse can occur during any rapid supraventricular tachycardia in these patients. In young athletes under 35, sudden death occurs fundamentally in patients with cardiomyopathy, usually, but not exclusively, of the hypertrophic variety. In co ...
Cardiac Rehabilitation
... cardiac surgery (CABG, valve replacement/repair, transplant, ventricular reductions surgery and congenital heart repair, LVAD), patients with compensate congestive heart failure. Gold standard of cardiac care after acute events ©2015 MFMER | 3449848-4 ...
... cardiac surgery (CABG, valve replacement/repair, transplant, ventricular reductions surgery and congenital heart repair, LVAD), patients with compensate congestive heart failure. Gold standard of cardiac care after acute events ©2015 MFMER | 3449848-4 ...
Cardiac Cycle - OpenStax CNX
... fully closed. There is a third heart sound, S3 , but it is rarely heard in healthy individuals. It may be the sound of blood owing into the atria, or blood sloshing back and forth in the ventricle, or even tensing of the chordae tendineae. S3 may be heard in youth, some athletes, and pregnant women ...
... fully closed. There is a third heart sound, S3 , but it is rarely heard in healthy individuals. It may be the sound of blood owing into the atria, or blood sloshing back and forth in the ventricle, or even tensing of the chordae tendineae. S3 may be heard in youth, some athletes, and pregnant women ...
diagnosis and prognosis of anomalous origin of the left coronary
... wall, which was not recognised before surgery. The coexistence of ALCAPA and VSD can be a dangerous combination. A large VSD may induce high pressure in the MPA, which preserves the left ventricular function due to reduced steal or even antegrade perfusion through the ALCAPA. If the VSD is closed an ...
... wall, which was not recognised before surgery. The coexistence of ALCAPA and VSD can be a dangerous combination. A large VSD may induce high pressure in the MPA, which preserves the left ventricular function due to reduced steal or even antegrade perfusion through the ALCAPA. If the VSD is closed an ...
Mitral Valve Repair Results in Better Right Ventricular Remodelling
... Introduction: Right ventricular (RV) remodelling may be an important determinant of clinical outcome in patients undergoing mitral valve surgery for mitral regurgitation. In the present study we hypothesised that, compared to valve replacement, mitral valve repair for degenerative mitral regurgitati ...
... Introduction: Right ventricular (RV) remodelling may be an important determinant of clinical outcome in patients undergoing mitral valve surgery for mitral regurgitation. In the present study we hypothesised that, compared to valve replacement, mitral valve repair for degenerative mitral regurgitati ...
Does asymptomatic patients with very frequent ventricular ectopy
... • Definition: LVEF of ≤50% in the absence of any detectable underlying heart disease and improvement of LVEF≥15% following effective treatment of index ventricular • Incidence: 6.8% in patients with idiopathic ventricular arrhythmias • Predictors: gender, absence of symptoms, PVC burden, the presenc ...
... • Definition: LVEF of ≤50% in the absence of any detectable underlying heart disease and improvement of LVEF≥15% following effective treatment of index ventricular • Incidence: 6.8% in patients with idiopathic ventricular arrhythmias • Predictors: gender, absence of symptoms, PVC burden, the presenc ...
Mitral Valve Repair: Settling the Controversies p3
... Some argue that patients in levels 1 and 2 should be medically managed and monitored by regular echocardiography. They maintain that asymptomatic patients should be spared the risks of surgery until it is absolutely necessary – especially since early repair does not affect long-term survival. Others ...
... Some argue that patients in levels 1 and 2 should be medically managed and monitored by regular echocardiography. They maintain that asymptomatic patients should be spared the risks of surgery until it is absolutely necessary – especially since early repair does not affect long-term survival. Others ...
Prospective Evaluation of Relatives for Familial Arrhythmogenic
... Sachdev are supported by Junior Fellowship Grants from the British Heart Foundation and the 5th Framework Program Research and Technological Development of the European Commission. ...
... Sachdev are supported by Junior Fellowship Grants from the British Heart Foundation and the 5th Framework Program Research and Technological Development of the European Commission. ...
Heart failure In Dogs
... ventricle is the major pumping muscle (or chamber) of the heart, the ability of the heart to pump and circulate blood is markedly reduced. Thus this results in a damming back of blood from the left ventricle. Since the left ventricle cannot empty fully it becomes stretched and dilated. This results ...
... ventricle is the major pumping muscle (or chamber) of the heart, the ability of the heart to pump and circulate blood is markedly reduced. Thus this results in a damming back of blood from the left ventricle. Since the left ventricle cannot empty fully it becomes stretched and dilated. This results ...
Ch19.Heart_1
... The superior part of the interA part of the aorta is narrowed, ventricular septum fails to form; increasing the workload of thus, blood mixes between the the left ventricle. two ventricles. More blood is shunted from left to right because the left ventricle is stronger. ...
... The superior part of the interA part of the aorta is narrowed, ventricular septum fails to form; increasing the workload of thus, blood mixes between the the left ventricle. two ventricles. More blood is shunted from left to right because the left ventricle is stronger. ...
Original Articles - Circulation: Heart Failure
... Background—Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with left ventricular diastolic dysfunction, without the diagnosis of congestive heart failure (HF) and with normal systolic function. Our objective was to determine the risk factors associated with the progressi ...
... Background—Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with left ventricular diastolic dysfunction, without the diagnosis of congestive heart failure (HF) and with normal systolic function. Our objective was to determine the risk factors associated with the progressi ...
Clinical Assessment in Acute Heart Failure
... can be attributed to worsening chronic HF, and approximately 40-50% of this group have a preserved ejection fraction. The remaining cases present with de novo AHF, often sec ondary to acute coronary syndromes.2 Symptoms are predominantly the result of systemic and pulmonary congestion due to elevat ...
... can be attributed to worsening chronic HF, and approximately 40-50% of this group have a preserved ejection fraction. The remaining cases present with de novo AHF, often sec ondary to acute coronary syndromes.2 Symptoms are predominantly the result of systemic and pulmonary congestion due to elevat ...
Treatment of Congestive Cardiac Failure
... congestion. If the cough does not improve, it becomes likely that the cough is related to the ACE inhibitor. 3) Beta-blockers Beta-blockers should be administered to patients with symptomatic heart failure when their condition is stabilized with oral medications. However, not all betablockers have t ...
... congestion. If the cough does not improve, it becomes likely that the cough is related to the ACE inhibitor. 3) Beta-blockers Beta-blockers should be administered to patients with symptomatic heart failure when their condition is stabilized with oral medications. However, not all betablockers have t ...
A Potentially Useful Marker to Determine for Left Ventricular
... branch block (LBBB) is an independent risk factor for the cardiac mortality [2]. In recent studies, progressive cardiomyopathy (CMP) can develop specific to the isolated LBBB [3]. Widespread myocardial damage and fibrosis or the disruptions of intercellular communication in dilated cardiomyopathy (D ...
... branch block (LBBB) is an independent risk factor for the cardiac mortality [2]. In recent studies, progressive cardiomyopathy (CMP) can develop specific to the isolated LBBB [3]. Widespread myocardial damage and fibrosis or the disruptions of intercellular communication in dilated cardiomyopathy (D ...
Echocardiography in the Normal Neonate
... order to minimize cardiac rotation. All examinations were performed without sedation with subject in supine position during normal respirations. The controls on the ultrasonoscope were set so that the depth compensation was not in use. The damping control setting was ...
... order to minimize cardiac rotation. All examinations were performed without sedation with subject in supine position during normal respirations. The controls on the ultrasonoscope were set so that the depth compensation was not in use. The damping control setting was ...
pericarditis - UMF IASI 2015
... (diastolic dip). 3. In mid-diastole, the chambers reach the maximum volume that the constraining pericardium will allow, and filling abruptly ceases (plateau phase). 4. The atrial pressure is equilibrated with the ventricles in early diastole (all four chambers filling pressure and pulmonary wedge p ...
... (diastolic dip). 3. In mid-diastole, the chambers reach the maximum volume that the constraining pericardium will allow, and filling abruptly ceases (plateau phase). 4. The atrial pressure is equilibrated with the ventricles in early diastole (all four chambers filling pressure and pulmonary wedge p ...
Pak Heart J - Pakistan Heart Journal
... Electrical conduction of the heart and mechanical activity of the heart are much dependent upon each other. Changes in one may have tremendous effect on the other and may result in significant difference in the outcome of different diseases. Impor tance of ventricular activation and ventricular mech ...
... Electrical conduction of the heart and mechanical activity of the heart are much dependent upon each other. Changes in one may have tremendous effect on the other and may result in significant difference in the outcome of different diseases. Impor tance of ventricular activation and ventricular mech ...
Safety of Asynchronous Ventricular Pacemaker - DGK
... In particular, patients with prior myocardial infarction, reduced left ventricular function and frequent spontaneous arrhythmias appear to be at risk. In normal hearts, ventricular fibrillation can be induced by above threshold stimuli during the vulnerable phase within the relative refractory perio ...
... In particular, patients with prior myocardial infarction, reduced left ventricular function and frequent spontaneous arrhythmias appear to be at risk. In normal hearts, ventricular fibrillation can be induced by above threshold stimuli during the vulnerable phase within the relative refractory perio ...
INTRODUCTION - California Tumor Tissue Registry
... tumoral extension to the IVC and right atrium),5 acute myocardial infarction,12 and severe acute pulmonary edema.2 Although initially appearing to be atrial in origin some CLs arise from vessel musculature of the vena cava or pulmonary veins, and only secondarily involve the heart.8 Only 21 cases ha ...
... tumoral extension to the IVC and right atrium),5 acute myocardial infarction,12 and severe acute pulmonary edema.2 Although initially appearing to be atrial in origin some CLs arise from vessel musculature of the vena cava or pulmonary veins, and only secondarily involve the heart.8 Only 21 cases ha ...
ST Segment Elevation Myocardial Infarction following Valve
... Pede F, Raviele A. Mitral valve repair complicated by iatrogenic coronary artery lesion treated with percutaneous coronary intervention. J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):180-1. Grande AM, Fiore A, Massetti M, Vigano M. Iatrogenic circumflex coronary lesion in mitral valve surgery: case r ...
... Pede F, Raviele A. Mitral valve repair complicated by iatrogenic coronary artery lesion treated with percutaneous coronary intervention. J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):180-1. Grande AM, Fiore A, Massetti M, Vigano M. Iatrogenic circumflex coronary lesion in mitral valve surgery: case r ...
Apical Hypertrophic Cardiomyopathy
... We have described a novel approach to the management of a challenging therapeutic dilemma: symptomatic apical HCM with dangerous pressure gradients and progressive thinning of the distal apical wall. To our knowledge, ours is the first reported use of subselective, modified-protocol ASA to treat an ...
... We have described a novel approach to the management of a challenging therapeutic dilemma: symptomatic apical HCM with dangerous pressure gradients and progressive thinning of the distal apical wall. To our knowledge, ours is the first reported use of subselective, modified-protocol ASA to treat an ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.