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Determinants of stroke volume and systolic and
Determinants of stroke volume and systolic and

... insight into the sensitivity of Ps, Pd, and SV to cardiac and arterial parameters and, second, to derive empirical formulas that give an accurate description of Ps, Pd, and SV Using dimensional analysis, we identified the major cardiac and arterial parameters that contribute to Ps, Pd, and SV We fou ...
Transcatheter Heart Valve Replacement - Hall
Transcatheter Heart Valve Replacement - Hall

... Patients whose native aortic valve only has one or two leaflets (usually due to a birth defect), normally there are 3 Patients who have a blood clot or an abnormal growth on their native valve Patients who have an infection in the heart or infections elsewhere Patients who already have a prosthetic ...
Cardiac Channelopathies and Sudden Death: Recent Clinical and
Cardiac Channelopathies and Sudden Death: Recent Clinical and

... Brugada syndrome (BrS), short QT syndrome (SQTS), and catecholaminergic polymorphic ventricular tachycardia (CPVT) are characterized by malignant arrhythmias in a normal heart resulting from genetic alterations in ion channels or associated proteins. Recent studies have found that about 30% of negat ...
Run for your life … at a comfortable speed and not too far
Run for your life … at a comfortable speed and not too far

... septum and RV (figure 3).12 Cardiologists from Minnesota evaluated a group of runners who had completed at least 25 marathons over 25 years and found a 60% increase in coronary plaque burden compared with sedentary age-matched controls.1 These findings were replicated by a group from Germany, who show ...
Full version (PDF file)
Full version (PDF file)

... intervention as contraindication for OHTX. Therefore, comparing heart transplantation with and without prior VAD implantation would be ethically controversial. ...
Arrhythmia in Pediatric
Arrhythmia in Pediatric

... of kent) between the atrium and the ventricle, by passing the normal delay of conduction in the AV node. The premature depolarization of aventricle produces adelta wave and results in prolongation of the QRS duration Criteria for WPW ...
Fulltext: english,
Fulltext: english,

... In trained and functionally fit athletes with a healthy heart, acute cardiovascular incidents due to training are very scarce. Regular physical exercise, controlled and adapted to physical conditions has beneficial effects surpassing hazards. If the principles of physical training are considered, po ...
Pulmonary artery and right ventricle function in
Pulmonary artery and right ventricle function in

... pulmonary artery (PA) has shown the same histological degeneration in BAV patients, especially after application of Ross procedure.[7] Some studies indicate that BAV patients have drastic changes in both the ascending aorta and medial layer of the pulmonary trunk earlier than patients with tricuspid ...
Congestive Heart Failure
Congestive Heart Failure

... Congress of the American Association for Respiratory Care, held December 3–6, 2005, in San Antonio, Texas. Correspondence: Michael S Figueroa MD, Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, 7704 ...
Congestive Heart Failure: Diagnosis, Pathophysiology, Therapy, and Implications for Respiratory Care
Congestive Heart Failure: Diagnosis, Pathophysiology, Therapy, and Implications for Respiratory Care

... CONGESTIVE HEART FAILURE: DIAGNOSIS, PATHOPHYSIOLOGY, THERAPY, AND IMPLICATIONS FOR RESPIRATORY CARE interstitium. At this point, by action of pressure gradients, fluid will form in the interlobular septae and the perihilar region. As noted above, chronic heart failure is associated with increased ...
Cardiac Arrhythmias (Part 2)
Cardiac Arrhythmias (Part 2)

... adult patients with atrial fibrillation at operation. Measurements of the length of a segment of the left ventricle by means of a mercury-filled resistance gauge were made together with arterial pressure and left ventricular end-diastolic pressure. Variations of end-diastolic segment length and pres ...
Congestive Heart Failure
Congestive Heart Failure

... CONGESTIVE HEART FAILURE: DIAGNOSIS, PATHOPHYSIOLOGY, THERAPY, AND IMPLICATIONS FOR RESPIRATORY CARE interstitium. At this point, by action of pressure gradients, fluid will form in the interlobular septae and the perihilar region. As noted above, chronic heart failure is associated with increased ...
Stochastic Aspects of Cardiac Arrhythmias
Stochastic Aspects of Cardiac Arrhythmias

... features of the heartprint that are reproduced in theoretical models. In parasystole, there is an independent pacemaker in the ventricle that beats with its own frequency and competes with the sinus rhythm for control of the ventricles. In some circumstances, the parasystolic rhythm is only marginal ...
Shift in sleep apnoea type in heart failure
Shift in sleep apnoea type in heart failure

... apnoea (CSA and OSA, respectively) over time coincides with improvement in left ventricular ejection fraction (LVEF). Therefore, sleep studies and LVEFs of HF patients with CSA from the control arm of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Fa ...
Efficacy, Safety, and Outcomes of Catheter Ablation of Atrial
Efficacy, Safety, and Outcomes of Catheter Ablation of Atrial

... period. If conduction gaps were present or if the pulmonary veins were not isolated during the redo procedure, ablation was performed according to the ablation scheme used during the first procedure. Successful CA was defined as the maintenance of SR without antiarrhythmic drug therapy after procedure ...
ct aortagram - Stanley Radiology
ct aortagram - Stanley Radiology

...  Resection with primary end-to-end anastomosis[6], patch aortoplasty with prosthetic material homograft or autologous subclavian artery.  Bypass grafting with a prosthetic tube or autologous vascular grafts. The most common technique in current use is resection with end-to-end anastomosis.  Ballo ...
Impact of Cardiac Contractility Modulation on Left Ventricular Global
Impact of Cardiac Contractility Modulation on Left Ventricular Global

... treatment status of CCM. Furthermore, as CCM was delivered intermittently (5 h/day), the follow-up echocardiography was performed at the time of no active CCM signals delivered in order to maintain the blinding of image acquisition. Real-time 3D echocardiography. Real-time 3D echocardiography was pe ...
Morphology: Allograft Heart Valves
Morphology: Allograft Heart Valves

... various layers of the valves. In addition, interstitial dendritic cells also have been demonstrated to be present in heart valves. These cells are thin, uninucleated and have very slender, elongated cytoplasmic processes, but lack basement membranes and actin filaments. They are similar to cells of t ...
Cardiac Resynchronisation Therapy: The Optimal QRS Duration
Cardiac Resynchronisation Therapy: The Optimal QRS Duration

... presence of QRS widening and left bundle branch block (LBBB) configuration on the electrocardiogram. Biventricular pacing by atrial-synchronised pacing of the right ventricle and left ventricle via the coronary sinus to the basal or midventricular left ventricle region accomplishes reverse remodelli ...
Expert consensus for multi-modality imaging evaluation of
Expert consensus for multi-modality imaging evaluation of

... apparent several years after irradiation. RIHD holds a wide range of deleterious effects on the heart including pericarditis, coronary artery disease (CAD), myocardial infarction, valvular heart disease, rhythm abnormalities, and non-ischaemic myocardial and conduction system damages. The number of ...
Total Anomalous Pulmonary Venous Drainage - Heart
Total Anomalous Pulmonary Venous Drainage - Heart

... Though this anomaly has been known for more than two centuries (Snellen and Dekker, 1963; Brody, 1942), it is only in the past decade that surgical correction (Muller, 1951), especially in infants (Cooley and Ochsner, 1957), has been possible. The present series has been collected largely from 1000 ...
In vivo dispersion in repolarization and arrhythmias in - AJP
In vivo dispersion in repolarization and arrhythmias in - AJP

... underlying pathophysiology differs. Furthermore, whole dispersion in RT is sensitive to the dimensions of the area of assessment, and if the entire endocardium or epicardium has not been mapped, we may assume that the total RT is an underestimation of the real total RT in this study (and in other st ...
File
File

... • Anterior interventricular sulcus – Anterior position of interventricular septum ...
The Clinical Value of Mitral A-Wave Deceleration Time in the
The Clinical Value of Mitral A-Wave Deceleration Time in the

... who were unaware of the study protocol, with an ATLUM9 ultrasound unit, using a 2.5 MHz phased array transducer. LV filling was assessed with pulsed-wave Doppler echocardiography. Measurements were obtained with the transducer in the apical four-chamber view, and the Doppler beam aligned as perpendi ...
Mechanical Dyssynchrony Precedes QRS Widening in ATPSensitive
Mechanical Dyssynchrony Precedes QRS Widening in ATPSensitive

... cardiomyopathic ventricles of the KATP channel–null mutant exposed to hemodynamic stress. Not observed in wild-type counterparts, intraventricular disparity in wall motion, validated by the degree, direction, and delay of myocardial speckle patterns, unmasked the disease substrate from asymptomatic ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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