List of Research Projects and Faculty 2017
... instrumentation and perform analysis of metabolites in a set of serum samples collected from patients with various metabolic conditions, including NAFLD and cancer (this work is to be performed both at Inova and at PW campus) ...
... instrumentation and perform analysis of metabolites in a set of serum samples collected from patients with various metabolic conditions, including NAFLD and cancer (this work is to be performed both at Inova and at PW campus) ...
Aptamers as Drugs. PDF
... With the wide variety of targeting capability of aptamers, it was soon realized that these ligands can be used as carriers for known drugs to a therapeutic site of interest. For example, cancer cells were targeted by conjugating an aptamer to doxorubicin23. The aptamer binds to a membrane-specific a ...
... With the wide variety of targeting capability of aptamers, it was soon realized that these ligands can be used as carriers for known drugs to a therapeutic site of interest. For example, cancer cells were targeted by conjugating an aptamer to doxorubicin23. The aptamer binds to a membrane-specific a ...
- Pacific Biomarkers
... including neuropeptide Y and pancreatic polypeptide (PP). The peptides of this family mediate their effects through several G protein-coupled receptors. PYY is primarily released from endocrine cells of the distal digestive tract and plays an important role in regulating food intake and energy balan ...
... including neuropeptide Y and pancreatic polypeptide (PP). The peptides of this family mediate their effects through several G protein-coupled receptors. PYY is primarily released from endocrine cells of the distal digestive tract and plays an important role in regulating food intake and energy balan ...
Articles in PresS. J Neurophysiol (March 20, 2003). 10.1152/jn
... single unit recordings in the neostriatum, an input structure of the basal ganglia, that reveal a wide range of neural activity associated with sensory stimuli, with motor planning as well as execution, and with working memory and other cognitive functions (Schultz et al. 1995). A surprising new fin ...
... single unit recordings in the neostriatum, an input structure of the basal ganglia, that reveal a wide range of neural activity associated with sensory stimuli, with motor planning as well as execution, and with working memory and other cognitive functions (Schultz et al. 1995). A surprising new fin ...
Target-cell-specific concentration of a metabotropic glutamate
... terminals is regulated by presynaptic receptors responding to transmitters released fro m the same nerve terminal or from terminals of other neurons. The release of glutamate, the major excitatory neurotransmitter, is suppressed by presynaptic auto· receptors'-J. Here we show that a metabotropic glu ...
... terminals is regulated by presynaptic receptors responding to transmitters released fro m the same nerve terminal or from terminals of other neurons. The release of glutamate, the major excitatory neurotransmitter, is suppressed by presynaptic auto· receptors'-J. Here we show that a metabotropic glu ...
Acute poisonings with substance of abuse
... improve airways patency if necessary (thrust the jaw forward for example) and avoid accidental injuries from the patient if his moves are uncontrolled. You can always identify simulation or hysteric coma by opening the eyes of the patient: in case of simulating conscious patients or hysteric patient ...
... improve airways patency if necessary (thrust the jaw forward for example) and avoid accidental injuries from the patient if his moves are uncontrolled. You can always identify simulation or hysteric coma by opening the eyes of the patient: in case of simulating conscious patients or hysteric patient ...
Activity 1 - Web Adventures
... down the axon (signal speed is approximately 2 meters per second). In a myelinated axon, only those ion channels in the gaps between the myelin sheaths are opened. The action potential “jumps” between the myelin sheaths, which is much faster - the signal reaches a speed of approximately 120 meters p ...
... down the axon (signal speed is approximately 2 meters per second). In a myelinated axon, only those ion channels in the gaps between the myelin sheaths are opened. The action potential “jumps” between the myelin sheaths, which is much faster - the signal reaches a speed of approximately 120 meters p ...
High-Resolution Labeling and Functional Manipulation of Specific
... promoters, viral-mediated delivery can often achieve high-level gene expression and thus bright labeling of fine structures such as neuronal synapses [13–15]. In addition, viral transfection can be targeted to specific brain regions and developmental stages by stereotactic injection [16]. Furthermor ...
... promoters, viral-mediated delivery can often achieve high-level gene expression and thus bright labeling of fine structures such as neuronal synapses [13–15]. In addition, viral transfection can be targeted to specific brain regions and developmental stages by stereotactic injection [16]. Furthermor ...
Ramayya, A. G., Zaghloul, K. A., Weidemann, C. T., Baltuch, G. H.
... To understand the function of SN DA and GABA neurons, we sought to extract the activity of these neuronal populations from microelectrode recordings. Because pars compacta and pars reticulata are largely interspersed in the primate SN (Poirier et al., 1983), the location of the microelectrode relati ...
... To understand the function of SN DA and GABA neurons, we sought to extract the activity of these neuronal populations from microelectrode recordings. Because pars compacta and pars reticulata are largely interspersed in the primate SN (Poirier et al., 1983), the location of the microelectrode relati ...
Astrocyte-Neuron Interactions during Learning May Occur by Lactate
... and debate in the field. During the last two decades a large number of studies by many different investigators have been carried out to prove or disprove this hypothesis. Whatever the study and the specific outcome, the intercellular trafficking of lactate was always interpreted as movement of fuel, ...
... and debate in the field. During the last two decades a large number of studies by many different investigators have been carried out to prove or disprove this hypothesis. Whatever the study and the specific outcome, the intercellular trafficking of lactate was always interpreted as movement of fuel, ...
protein, glutathione, essential oils, energy, weight loss
... Among the most beneficial and effective supplements in any sports nutrition program are branched chain amino acids (BCAA). These are the essential amino acids leucine, isoleucine, and valine. These amino acids have been investigated for their potential anticatabolic (preventing muscle breakdown) and ...
... Among the most beneficial and effective supplements in any sports nutrition program are branched chain amino acids (BCAA). These are the essential amino acids leucine, isoleucine, and valine. These amino acids have been investigated for their potential anticatabolic (preventing muscle breakdown) and ...
Slide 1 - AccessPharmacy
... Diagram of the olfactory pathway. Information is transmitted from the olfactory bulb by axons of mitral and tufted relay neurons in the lateral olfactory tract. Mitral cells project to five regions of the olfactory cortex: anterior olfactory nucleus, olfactory tubercle, piriform cortex, and parts of ...
... Diagram of the olfactory pathway. Information is transmitted from the olfactory bulb by axons of mitral and tufted relay neurons in the lateral olfactory tract. Mitral cells project to five regions of the olfactory cortex: anterior olfactory nucleus, olfactory tubercle, piriform cortex, and parts of ...
Ch18 Lecture
... •Many amines with medicinal properties are sold as their ammonium salts, which are transported through the aqueous bloodstream. •Some examples include Sudafed, sold as the ...
... •Many amines with medicinal properties are sold as their ammonium salts, which are transported through the aqueous bloodstream. •Some examples include Sudafed, sold as the ...
here - Aerotoxic Association
... have demonstrated substantial increases in the autophosphorylation,36,37 enzymatic activity,38 protein levels, and mRNAs of CaM kinase II in hens treated with diisopropylphosphorofluoridate (DFP).39 These aberrant alterations have resulted in increased phosphorylation of the following cytoskeletal p ...
... have demonstrated substantial increases in the autophosphorylation,36,37 enzymatic activity,38 protein levels, and mRNAs of CaM kinase II in hens treated with diisopropylphosphorofluoridate (DFP).39 These aberrant alterations have resulted in increased phosphorylation of the following cytoskeletal p ...
Depression is a widespread illness with an estimated 340
... monoamines in the presynaptic cells. It has been proposed that high levels of MAO-A could cause too great a reduction of monoamines in the neurons and result in depression (Friedman & Anderson, 2011). Research by Meyer, et al. (2006) used PET scanning technology to compare the levels of MAOA in the ...
... monoamines in the presynaptic cells. It has been proposed that high levels of MAO-A could cause too great a reduction of monoamines in the neurons and result in depression (Friedman & Anderson, 2011). Research by Meyer, et al. (2006) used PET scanning technology to compare the levels of MAOA in the ...
Glossary OF terms in Spinal Cord Injury Research
... controversial. Some investigators consider the period to be relatively short, i.e. several hours during which treatments can be given to prevent progressive or secondary tissue damage. Other investigators may consider the acute period to extend several weeks, during which there may be Wallerian dege ...
... controversial. Some investigators consider the period to be relatively short, i.e. several hours during which treatments can be given to prevent progressive or secondary tissue damage. Other investigators may consider the acute period to extend several weeks, during which there may be Wallerian dege ...
Localization of the P1 protein of potato Y potyvirus in association
... The occurrence of inclusions in potyvirus-infected cells makes it easy to determine with the electron microscope which cells are infected. PVY encodes a cylindrical inclusion protein that aggregates in the cytoplasm of infected cells to form inclusions resembling pinwheels (Fig. 3 b–d) or bundles wh ...
... The occurrence of inclusions in potyvirus-infected cells makes it easy to determine with the electron microscope which cells are infected. PVY encodes a cylindrical inclusion protein that aggregates in the cytoplasm of infected cells to form inclusions resembling pinwheels (Fig. 3 b–d) or bundles wh ...
The nerve A nerve is an enclosed, cable
... endoneurial fluid may increase at the site of irritation. This increase in fluid can be visualized using magnetic ...
... endoneurial fluid may increase at the site of irritation. This increase in fluid can be visualized using magnetic ...
WALDENSTROM`S AND PERIPHERAL NEUROPATHY by
... Moreover, most patients with peripheral neuropathies have relatively mild symptoms that do not progress to severe neuropathies, and there is not much evidence to show that starting therapy with chemotherapy or plasmapheresis for a mild neuropathy will delay the progression to a more severe neuropath ...
... Moreover, most patients with peripheral neuropathies have relatively mild symptoms that do not progress to severe neuropathies, and there is not much evidence to show that starting therapy with chemotherapy or plasmapheresis for a mild neuropathy will delay the progression to a more severe neuropath ...
Portal Hypertension
... 2 - lethargic, inappropriate behavior, disoriented for time 3 - somnolent but arousable; confused 4 - coma/unarousable ...
... 2 - lethargic, inappropriate behavior, disoriented for time 3 - somnolent but arousable; confused 4 - coma/unarousable ...
Chronic Pain
... identify the type, intensity and bodily location of the noxious event. • The affective-emotional response to the noxious stimulus is mediated by the limbic system. Pain has an inseparable affective-emotional component that defines the response and associated behavior resulting from the initiating no ...
... identify the type, intensity and bodily location of the noxious event. • The affective-emotional response to the noxious stimulus is mediated by the limbic system. Pain has an inseparable affective-emotional component that defines the response and associated behavior resulting from the initiating no ...
Clean Lean Protein Powde
... It’s the best choice for everyone Clean Lean Protein is great for kids and adults alike. It has something for everyone. It has The Alkaline Advantage and high protein content for athletes. Its low allergenic profile is perfect for allergy sufferers and its low fat profile is great for those watching ...
... It’s the best choice for everyone Clean Lean Protein is great for kids and adults alike. It has something for everyone. It has The Alkaline Advantage and high protein content for athletes. Its low allergenic profile is perfect for allergy sufferers and its low fat profile is great for those watching ...
CHAPTER 12: THE CENTRAL NERVOUS SYSTEM MODULE 12.1
... Amygdala – anterior to hippocampus; involved in behavior and expression of emotion, especially fear ...
... Amygdala – anterior to hippocampus; involved in behavior and expression of emotion, especially fear ...
Identification of neural circuits involved in female genital responses
... the thoracolumbar spinal region that innervate the axial musculature, as well as to lumbosacral neurons that innervate the pelvic organs (17, 18, 27, 29, 51, 61). The PAG also receives direct inputs from the lumbosacral spinal cord (34, 36, 37, 62, 96) and may function to integrate ascending and des ...
... the thoracolumbar spinal region that innervate the axial musculature, as well as to lumbosacral neurons that innervate the pelvic organs (17, 18, 27, 29, 51, 61). The PAG also receives direct inputs from the lumbosacral spinal cord (34, 36, 37, 62, 96) and may function to integrate ascending and des ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.