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The Preoptic Nucleus in Fishes: A Comparative Discussion of
The Preoptic Nucleus in Fishes: A Comparative Discussion of

... system. However, where and how gonadotropin acts is an open question. Of course stimuli other than those indicated above also impinge on this circuit, including such factors as the presence or absence of a mate and environmental conditions. For example, a pheromone from ovulated eggs and ovarian flu ...
CONTROL OF FOOD INTAKE: NEUROBIOLOGICAL ASPECTS S
CONTROL OF FOOD INTAKE: NEUROBIOLOGICAL ASPECTS S

... Food that covers energetic needs is generally not constantly available. In addition, food intake behaviour is not compatible with some physiological states such as sleep. Therefore, food intake in all mammals is a discontinuous behaviour organised in discrete meals. The continuous, but variable, nee ...
Neurons & the Nervous System
Neurons & the Nervous System

... (think! don’t say the answer out loud…yet) ...
The antioxidants alpha-lipoic acid and N
The antioxidants alpha-lipoic acid and N

... • Free radical damage from oxidative stress (Reactive oxygen species, ROS) has long been thought to play an important role in age-related neurodegenerative disorders • Free radicals are produced by the mitochondria in cells as a side effect of energy production from food. • Emerging consensus that ...
The six urea cycle disorders
The six urea cycle disorders

... episodes of hyperammonemia (high ammonia levels in the blood) may be brought on by viral illnesses including chicken pox, high-protein meals, or even exhaustion. The condition is sometimes misdiagnosed as Reye’s Syndrome. Childhood onset can be seen in both boys and ...
ALS - AJNR Blog
ALS - AJNR Blog

... • Single gene mutations can lead to selective motor neuron loss ...
A Critical Review of the Role of the Proposed VMpo Nucleus in Pain
A Critical Review of the Role of the Proposed VMpo Nucleus in Pain

... nervous system nuclei is usually based on cytoarchitecture, rather than on fiber architecture, although the patterns of connections of a nucleus are obviously important. A major problem is that it is unclear to what extent the calbindin-positive axons in this case terminate in the proposed nucleus a ...
Spindle-Like Thalamocortical Synchronization in a Rat Brain Slice
Spindle-Like Thalamocortical Synchronization in a Rat Brain Slice

... VB and RTN following stimuli delivered in the cortex. Spontaneous and stimulus-induced coherent rhythmic oscillations (duration ⫽ 0.4 – 3.5 s; frequency ⫽ 9 –16 Hz) occurred in cortex, VB, and RTN during application of medium containing low concentrations of the K⫹ channel blocker 4-aminopyridine (0 ...
What Do Mirror Neurons Mean?
What Do Mirror Neurons Mean?

... does not need mirror neurons to take the teleological stance, as it is based not on 'embodied simulation' or 'intentional attunement' but on evaluation of efficiency. This evaluation may rely on information from one's own motor system, but it does not have to do so. This was shown in our experiments ...
BASAL GANGLIA
BASAL GANGLIA

BASAL GANGLIA
BASAL GANGLIA

... FUNCTIONS OF BASAL GANGLIA ...
Anatomy and regulation of the central melanocortin system
Anatomy and regulation of the central melanocortin system

... upregulates levels of AgRP and NPY mRNA (5–10×) and modestly decreases POMC mRNA levels (20–50%), and leptin replacement to pre-fasting levels normalizes expression of these genes28–30. Before the discovery of leptin as the principal adipostatic hormone, extensive research on insulin demonstrated th ...
as pdf - Hypnosis Unit UK
as pdf - Hypnosis Unit UK

... to its painful level but they were asked to imagine the heat pain as clearly as possible in response to a single tap and its termination on a double tap signal. The major experimental finding of this study was that the hypnotically induced pain condition produced widespread activity in brain areas t ...
Breaking Haller`s Rule: Brain-Body Size Isometry in a
Breaking Haller`s Rule: Brain-Body Size Isometry in a

... what was expected from previous applications of Haller’s rule. A trade-off between brain performance and the energetic costs of having a large brain may explain this: a further increase in relative brain size may be too costly for this wasp species in terms of energy expenditure [Aiello and Wheeler, ...
posterior pituitary
posterior pituitary

... Thyroid Stimulating Hormone (TSH) TSH (also known as thyrotropin) – glycoportein consisting of: a b chain of 112 amino acids and an a chain of 89 amino acids. The a chain is identical to that found in two other pituitary hormones, FSH and LH as well as in the hormone chorionic ...
Fine tuning of vestibular apparatus in terrestrial snail at Earth and
Fine tuning of vestibular apparatus in terrestrial snail at Earth and

... phase of long-term potentiation (LTP) of synaptic effectivity is critical for the storage of long-term memory. Although the expression of the early induction phase of LTP has been studied extensively (Bliss and Collingridge, 1993), the mechanism for synaptic enhancement and a possibility of its modi ...
Inborn Errors of Metabolism A Hospitalist`s Approach
Inborn Errors of Metabolism A Hospitalist`s Approach

... Metabolic disease is tough Often thought of later in illness ...
Jeopardy
Jeopardy

... cause the side effect of sweating, ironically it may be helpful to perimenopausal women with this ...
CLM  UMR-S 839 INSERM/UPMC Institut du Fer a Moulin
CLM UMR-S 839 INSERM/UPMC Institut du Fer a Moulin

... connectivity to animal behavior. It has become increasingly clear that such multifaceted approaches have further demonstrated the extent to which neuronal structure and function may undergo plastic changes that contribute to development, learning and diseases. The 5th IFM colloquium aims to explore ...
Reconstruction of the nigrostriatal dopamine pathway in the adult
Reconstruction of the nigrostriatal dopamine pathway in the adult

... Keywords: axon growth, cell transplantation, functional recovery, green fluorescent protein, Parkinson’s disease, regeneration ...
A single amino acid substitution in the haemagglutinin
A single amino acid substitution in the haemagglutinin

... intracerebral pathogenicity index (ICPI) tests. As shown in Table 3, the MDT in embryonated chicken eggs was 89 h for rAnh-wt, and 85 h for rAhn-I192M virus, while the ICPI values were 0.91 and 1.10, respectively. These results indicate that these viruses can be classified as mesogens, according to ...
(15 pages pdf)
(15 pages pdf)

... DopR mRNA in different genotypes by quantitative RT-PCR. There was an 50% reduction in the amount of DopR mRNA in DopR/+ flies and an 95% reduction in DopR/DopR files (Figure 2B). These data confirm prior analysis of the DopRf02676/dumb2 allele (Kim et al., 2007), as well as independent studies by ...
- Wiley Online Library
- Wiley Online Library

... understanding how actin cytoskeleton and its interaction with microtubules are precisely modulated in the growth cone. There are two kinds of cytoskeletal filaments, F-actin and microtubules, in the growth cone. The actin cytoskeleton, composed of actin polymers and a large variety of associated prot ...
Citron-Kinase, a Protein Essential to Cytokinesis in Neuronal
Citron-Kinase, a Protein Essential to Cytokinesis in Neuronal

... within clones isolated from exon 1 of fh/fh genomic DNA (chromatograms not shown). In addition, we find that the kinase domain of Citron-K gene is present in three P1 clones in a P1 contig of rat chromosome 12 that contains D12Rat55, which maps to the flathead mutation. Together, these results suggest ...
Rebuilding Brain Circuitry with Living Micro
Rebuilding Brain Circuitry with Living Micro

... degeneration as well as loss of long-distance axonal connections. While cell replacement and axonal pathfinding strategies are often explored independently, there is no strategy capable of simultaneously replacing lost neurons and re-establishing long-distance axonal connections in the central nervo ...
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Clinical neurochemistry



Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.
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