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Original Article Original Article
Original Article Original Article

... genes were upregulated in right atrial appendages of subjects with AF.13 Another study showed that inflammatory and transcription-related gene expression was increased in right atrial appendages of subjects with AF versus controls.14 These results highlight the adaptive responses to AF-induced stres ...
Paroxysmal Supraventricular Tachycardia
Paroxysmal Supraventricular Tachycardia

... Methods, Materials, and Clinical Patient Information Eight patients were studied in the nonsedated postabsorptive state after informed consent was obtained (table 1). All had symptomatic supraventricular tachycardia (SVT), and none demonstrated evidence of pre-excitation. No patient was taking antia ...
Right ventricular cardiac myxoma. Histopathology diagnosis in
Right ventricular cardiac myxoma. Histopathology diagnosis in

... seprum are still mysterious, and a search for primitive cell differentiating myxoma cell should be continued [21]. ...
WATCHMAN® Left Atrial Appendage Closure Device
WATCHMAN® Left Atrial Appendage Closure Device

... patients, the WATCHMAN Implant was compared to warfarin. The WATCHMAN Implant was found to be as effective as warfarin in reducing the risk of the combination of stroke (either from a blocked vessel or bleeding within the brain), cardiovascular death, or a blocked blood vessel in another part of the ...
Management of atrial fibrillation in patients with heart failure
Management of atrial fibrillation in patients with heart failure

... and (v) functional status and quality of life improve. Therefore, it is tempting to speculate that mortality, morbidity, and the need for hospitalization are reduced by a strategy aimed at achieving and maintaining sinus rhythm. Since 2000, five studies have been published comparing rhythm vs. rate c ...
Shortcut to Electrocardiography
Shortcut to Electrocardiography

... electrodes placed on the surface of the body will record waves of depolarization and repolarization as they sweep through the heart. ...
Catheter Ablation for Atrial Fibrillation
Catheter Ablation for Atrial Fibrillation

... be due to the inflammation caused by the ablation in the heart and does not mean the procedure has not worked. If you think you will be more comfortable then you can restart the AF medication that was stopped before you went home. If your medication was not stopped then it may be possible to increas ...
The Stroke Prevention in Atrial Fibrillation
The Stroke Prevention in Atrial Fibrillation

... adult disability in England2, costing more than £7 billion each year in direct and indirect costs.3 Recurrence of stroke amongst AF patients is more frequent, and disability can be more severe among survivors.7 Since stroke is too often the first sign of embolism in AF, identification and prevention ...
Cardiac Electrophysiology Basics
Cardiac Electrophysiology Basics

... override is accomplished by rapidly pacing the RA (Transonic-Scisense EP catheter at high position) and then turning off the pacing catheter waiting to see how long it takes to recover the SA node pacing activity. In disease states this time of recovery will be longer as compared to healthy hearts. ...
Review - p - the Health Science Program
Review - p - the Health Science Program

... atrial wall just below the opening of the superior vena cava. It is the primary pacemaker of the heart and has a normal firing rate of 60-100 beats per minute (BPM). Internodal Pathways: Consists of anterior, middle and posterior divisions that distribute electrical impulses generated by the SA node ...
Paediatric ECG Interpretation
Paediatric ECG Interpretation

... can be either an anatomically separate accessory pathway (the Bundle of Kent as in most cases of WolfParkinson-White) or a functionally separate pathway within the AV node (called AV nodal re-entry tachycardia). For SVT to occur the two pathways must have at least, temporarily, different conduction a ...
Relation of the HAS-BLED Bleeding Risk Score to Major Bleeding
Relation of the HAS-BLED Bleeding Risk Score to Major Bleeding

... HAS-BLED score were assessed. Cox regression models were used to determine the association between clinical risk factors and bleeding episodes, adverse cardiovascular events, and mortality. The median HAS-BLED score was 2 (range, 0 – 6; 29% with a score ⱖ3 [ie, high risk]). Median follow-up was 861 ...
Since the function of the heart is that of a pump it is of interest both to
Since the function of the heart is that of a pump it is of interest both to

... A, unknown; B, mitral stenosis; C, paroxysmal auricular fibrillation.4 On December 8, 1933, when auricular fibrillation was present, measurements of the circulation were made; these were repeated on December 11th, 2 days after restoration of normal sinus mechanism occurred spontaneously (Table I, Fi ...
Effect of Surgery for Atrial Fibrillation Associated With Mitral Valve
Effect of Surgery for Atrial Fibrillation Associated With Mitral Valve

... The remaining 5 patients in the intractable AF group were adequately anticoagulated (PT-INR, 2.13 to 2.56). The details of thromboembolism after AF surgery are presented in Table 2. Actuarial freedom from thromboembolism at 5 and 10 years was 96.5% in the sinus group; 82.4% and 78.1%, respectively, ...
Redefining the Blanking Period After Catheter Ablation for
Redefining the Blanking Period After Catheter Ablation for

... Congestive heart failure, hypertension, an age of ≥75 years, and diabetes mellitus are each assigned 1 point, and previous stroke or transient ischemic attack is assigned 2 points; the score is calculated by summing all the points for a given patient. ...
Left Atrial Enlargement and Reduced Physical Function During Aging
Left Atrial Enlargement and Reduced Physical Function During Aging

... Leung, Ross, & Thomas, 2011; Triposkiadis et al., 1995) and as a consequence of cardiovascular disease (Gottdiener, Kitzman, Aurigemma, Arnold, & Manolio, 2006; Pritchett et al., 2003). Left atrial enlargement correlates with decreased exercise capacity (Kjaergaard et al., 2005; Wong & Yeo, 2010), i ...
4 Arrhythmias in Children and Young Adults Harinder R. Singh
4 Arrhythmias in Children and Young Adults Harinder R. Singh

... periods. Sinus node dysfunction increases in frequency with age of the patient and time from surgery. 4.1.5 Clinical presentation: It depends on the age, underlying cardiac conduction abnormality, and hemodynamic status. Although majority of children with structurally normal hearts remain asymptomat ...
Clinical Examination: ECG library
Clinical Examination: ECG library

... 2 The ECG in Case 2 shows sinus rhythm: each QRS complex is preceded by a P wave which represents atrial contraction. Examples of other cardiac rhythms are shown later. 3 The PR interval is measured from the beginning of the P wave to the beginning of the QRS complex. The upper limit of normal is 20 ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... Postulated mechanisms have included a single focus in the proximal His bundle or bundle branches with alternating left fascicular block, or single or double foci in the distal His purkinje system and also reentry.10,12,13 Recently, Ping-Pong mechanism or reciprocating bigeminy in the distal his purk ...
(Level Ib evidence). - The Neurology Report
(Level Ib evidence). - The Neurology Report

... previous stroke, TIA, systemic embolism, symptomatic heart failure within the previous 3 months or a left ventricular ejection fraction ≤ 40%, diabetes mellitus, or hypertension requiring pharmacologic treatment ...
Chapter 13-cardiac 檔案
Chapter 13-cardiac 檔案

... regulation of blood flow to organs & receives fully ...
$doc.title

... studies  have  revealed  a  number   of  genes  that  appear  to  be   implicated  in  cardiovascular   disease.    Yet  these  GWAS  are   only  able  to  account  for  a  small   part  of  what  is  believed  to  the   role  gen ...
New Advances in the Diagnosis and Management of Cardioembolic
New Advances in the Diagnosis and Management of Cardioembolic

... aneurysm (ASA), atrial spontaneous echo contrast, mitral annulus calcification, mitral valve prolapse, calcified aortic stenosis, akinetic/dyskinetic ventricular wall segment, hypertrophic obstructive cardiomyopathy and congestive heart failure are low or uncertain risks. In many patients such as th ...
Why Do We Have Purkinje Fibers Deep in Our Heart?
Why Do We Have Purkinje Fibers Deep in Our Heart?

... equivalent of these components are present in some form in all vertebrate hearts (Sedmera et al. 2003), all morphologically distinct parts are present only in the heart of mammals. While development of the CCS has been subject to numerous reviews (Gourdie et al. 2003a,b, Christoffels et al. 2010, Bu ...
cardio i - jan 2015
cardio i - jan 2015

...  Usually associated with organic disease such as congestive heart failure (rarely seen with MI). ...
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Atrial fibrillation



Atrial fibrillation (AF or A-fib) is an abnormal heart rhythm characterized by rapid and irregular beating. Often it starts as brief periods of abnormal beating which become longer and possibly constant over time. Most episodes have no symptoms. Occasionally there may be heart palpitations, fainting, shortness of breath, or chest pain. The disease increases the risk of heart failure, dementia, and stroke.Hypertension and valvular heart disease are the most common alterable risk factors for AF. Other heart-related risk factors include heart failure, coronary artery disease, cardiomyopathy, and congenital heart disease. In the developing world valvular heart disease often occurs as a result of rheumatic fever. Lung-related risk factors include COPD, obesity, and sleep apnea. Other factors include excess alcohol intake, diabetes mellitus, and thyrotoxicosis. However, half of cases are not associated with one of these risks. A diagnosis is made by feeling the pulse and may be confirmed using an electrocardiogram (ECG). The typical ECG shows no P waves and an irregular ventricular rate.AF is often treated with medications to slow the heart rate to a near normal range (known as rate control) or to convert the rhythm to normal sinus rhythm (known as rhythm control). Electrical cardioversion can also be used to convert AF to a normal sinus rhythm and is often used emergently if the person is unstable. Ablation may prevent recurrence in some people. Depending on the risk of stroke either aspirin or anti-clotting medications such as warfarin or a novel oral anticoagulant may be recommended. While these medications reduce this risk, they increase rates of major bleeding.Atrial fibrillation is the most common serious abnormal heart rhythm. In Europe and North America, as of 2014, it affects about 2% to 3% of the population. This is an increase from 0.4 to 1% of the population around 2005. In the developing world about 0.6% of males and 0.4% of females are affected. The percentage of people with AF increases with age with 0.14% under 50 years old, 4% between 60 and 70 years old, and 14% over 80 years old being affected. A-fib and atrial flutter resulted in 112,000 deaths in 2013, up from 29,000 in 1990. The first known report of an irregular pulse was by John Baptist Senac in 1749. This was first documented by ECG in 1909 by Thomas Lewis.
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