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Hypergravity hinders axonal development of motor neurons
Hypergravity hinders axonal development of motor neurons

... Earth and its stable gravitational conditions. Altering gravity can have profound impacts on the human body. This is especially relevant with the possibility of long-term space travel and habitation and the associated changes in gravity in different space environments. Although some of the effects o ...
A Double-labeling Investigation of the Afferent Connectivity to
A Double-labeling Investigation of the Afferent Connectivity to

... the region of overlap of the two populations of single-labeled neurons. We concluded from this observation that the two branches of a bifurcating axon terminate in cortical regions representing the same portion of the visual field. Since then, several experimental results have led us to revise this ...
Hierarchical somatosensory processing
Hierarchical somatosensory processing

... In the caudal part of the gyrus, there are unique neurons that respond selectively to specific features of a stimulus some of these neurons arc [4,.5,X!]. In the monkey, activated better or solely by active hand movements, such as reaching [Zl]. Tremblay et al. [22] have reported that ...
The mirror neuron system and the consequences of its dysfunction
The mirror neuron system and the consequences of its dysfunction

Biological constraints limit the use of rapamycin
Biological constraints limit the use of rapamycin

Neurons in Anterior Cingulate Cortex Multiplex
Neurons in Anterior Cingulate Cortex Multiplex

... of the targets [the low value (LV) targets] turned red. The other one [the gyral, ACC (Rudebeck et al., 2006a)], and rostral to the cingulate motor high value (HV) target] turned one of six colors: dark gray, light gray, areas (Shima et al., 1991; Shima and Tanji, 1998). Additional details on orange ...
Striatal Plasticity and Basal Ganglia Circuit Function
Striatal Plasticity and Basal Ganglia Circuit Function

Learning place cells, grid cells and invariances: A unifying model
Learning place cells, grid cells and invariances: A unifying model

... The cellular and network mechanisms that give rise to each of these firing patterns are subject to extensive experimental and theoretical research. Several computational models have been suggested to explain the emergence of grid cells [9–21], place cells [11, 22–27] and head direction cells [11, 28 ...
Impaired Cl Extrusion in Layer V Pyramidal Neurons of Chronically
Impaired Cl Extrusion in Layer V Pyramidal Neurons of Chronically

... KCC2 is important in maintaining low [Cl⫺]i, resulting in hyperpolarizing GABA responses. Decreases in KCC2 after neuronal injuries result in increases in [Cl⫺]i and enhanced neuronal excitability due to depolarizing GABA responses. We used the gramicidin perforatedpatch technique to measure ECl (⬃E ...
Presynaptic Modulation of the Retinogeniculate Synapse
Presynaptic Modulation of the Retinogeniculate Synapse

... dextran dyes resulted in patchy labeling of the LGN when compared with that seen with the lipophilic indicator Di-I (Chen and Regehr, 2000), suggesting that a smaller population of RGCs was labeled (Fig. 3A, left). A high-power view of an intensely labeled region shows that the fluorescence arises f ...
Convergence in Mammalian Nucleus of Solitary Tract During
Convergence in Mammalian Nucleus of Solitary Tract During

... to 0.5 M NH,Cl, NaCl and KC1 are presented first. Chemicals were applied to the tongue for the period initiated at the arrowhead and concluded with dots (water rinses). Bottom,responses to electrical stimulation of individual fungiform papillae; numbers under the data represent each papilla. The rec ...
The Nervous System
The Nervous System

... a. helps control the functioning of most internal organs 3. controls hormone secretion by anterior and posterior pituitary glands a. indirectly helps control hormone secretion by most other endocrine glands 4. contains center for controlling appetite, wakefulness, pleasure, etc ii. structure and fun ...
Basal Ganglia: Mechanisms for Action Selection
Basal Ganglia: Mechanisms for Action Selection

... The basal ganglia appear to fulfill the criteria for such a central mechanism (Redgrave et al. 1999). The main input nucleus, the striatum, receives input from every region of cortex, from primary visual, auditory, and somatosensory cortex, through motor cortices, to the subregions of prefrontal cor ...
Detecting Action Potentials in Neuronal Populations with Calcium
Detecting Action Potentials in Neuronal Populations with Calcium

Signature - UNE Faculty/Staff Index Page
Signature - UNE Faculty/Staff Index Page

... Spray Simple Green on the greasy spot AND wipe until dry – just spraying is NOT enough. ...
The Spinal Cord
The Spinal Cord

Different Stimuli, Different Spatial Codes: A Visual Map and an
Different Stimuli, Different Spatial Codes: A Visual Map and an

... at varying elevations depending on the spatial sensitivity of the neuron under study ranged 216 to 6 degree (mean6SD: 24.264,1). Targets were either auditory (white noise burst) or visual (LED), presented from a stimulus array of 9 speakers each with an LED attached to its face. The speakers were sp ...
The neural encoding of self-generated and externally applied
The neural encoding of self-generated and externally applied

... Why   is   early   vestibular   processing   in   mice   characterized   by   lower   pathway   modulation  than  in  monkeys?  The  general  decrease  in  modulation  could  potentially   indicate   sensory   processing   has   adapted   to   ...
Document
Document

... to lamina IV, these tracts cells are also known as the Nucleus Proprius (e.g. spinal thalamic tract or anterolateral system; pain and temperature, some tactile) • Receives afferent input from dorsal roots and descending fibers, most importantly Corticospinal ...
Posterior White Column
Posterior White Column

... to lamina IV, these tracts cells are also known as the Nucleus Proprius (e.g. spinal thalamic tract or anterolateral system; pain and temperature, some tactile) • Receives afferent input from dorsal roots and descending fibers, most importantly Corticospinal ...
Multimodal Integration in Rostral Fastigial Nucleus Provides an
Multimodal Integration in Rostral Fastigial Nucleus Provides an

... Materials and Methods Three rhesus monkeys (Macaca mulatta) were prepared for chronic extracellular recording using aseptic surgical techniques. All experimental protocols were approved by the McGill University Animal Care Committee and were in compliance with the guidelines of the Canadian Council ...
Selective Loss of Catecholaminergic Wake–Active Neurons in a
Selective Loss of Catecholaminergic Wake–Active Neurons in a

... neuron identifier and cleaved caspase-3 (CC3) using polyclonal rabbit anti-cleaved caspase-3 primary antibody (1:500; Cell Signaling Technology, Danvers, MA). Specificity was confirmed with nonincubation with caspase-3 blocking peptide (Asp175; Cell Signaling Technology). Noradrenergic, cholinergic, ...
final scientific program
final scientific program

... learning, memory, cognition, perception, action and ultimately conscious awareness. Electrophysiological recordings in behaving animals over the past forty years have revealed considerable information about what the firing patterns of single neurons encode in isolation, but it remains largely a myst ...
Midbrain fMRI: Applications, Limitations and Challenges
Midbrain fMRI: Applications, Limitations and Challenges

Behavioral and Neural Changes after Gains and Losses of
Behavioral and Neural Changes after Gains and Losses of

... (Barraclough et al., 2004; Lee et al., 2004). During this game, the computer opponent simulated a rational decision maker who chooses its target so as to minimize the payoff of the animal, and the animal gained a token only when it chose the same target as the computer. When the animal’s choice was ...
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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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