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14-3: Human Molecular Genetics
14-3: Human Molecular Genetics

... the known markers on each chromosome ...
Nature Reviews Genetics, 10
Nature Reviews Genetics, 10

... of a species is of great evolutionary interest. Computational techniques have already been used to reconstruct ancestral genomes of several species, but these methods have limitations — in one algorithm, for example, only one species or a few outgroups can be compared at a time. In a recent paper, G ...
Chapter 14 - Genomes and genomics
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A History of Innovation in Genetic Analysis
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BIOL 433 Plant Genetics Term 1, 2005
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Genetics in Epidemiology - University of Pittsburgh
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... 8% occur in gene regulatory regions 40% occur in non-coding introns 40% occur in intergenic sequences Regions of high linkage disequilibrium are similar across populations ...
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Human Genome Project



The Human Genome Project (HGP) is an international scientific research project with the goal of determining the sequence of chemical base pairs which make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and functional standpoint. It remains the world's largest collaborative biological project. The project was proposed and funded by the US government; planning started in 1984, got underway in 1990, and was declared complete in 2003. A parallel project was conducted outside of government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centers in the United States, the United Kingdom, Japan, France, Germany, and China.The Human Genome Project originally aimed to map the nucleotides contained in a human haploid reference genome (more than three billion). The ""genome"" of any given individual is unique; mapping ""the human genome"" involves sequencing multiple variations of each gene.
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