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- Philsci
- Philsci

... Such an argument for biological determinism has been presented by Alex Rosenberg (1994) and Barbara Horan (1994). Since the argument is supposed to apply to the entire biological world, it is also relevant to a special type of organisms, namely metazoans equipped with a nervous system, such as leech ...
The peripheral nerves
The peripheral nerves

... The myelin, a protein-lipid complex that is wrapped around the axon . Outside the CNS, the myelin is produced by Schwann cells, glia-like cells found along the axon. Myelin forms when a Schwann cell wraps its membrane around an axon up to 100 times. The myelin sheath envelopes the axon except at its ...
Bidirectional propagation of Action potentials
Bidirectional propagation of Action potentials

... porebuilding proteins called ion channels. Consequently K+ ions diffuse down the ion gradient and leed to a negative charge inside the cell, consequently maintain the resting potential. If it is possible to change the membrane potential rapidly, the cell is excitable, such as nerves and muscles. A r ...
Activity-dependent editing of neuromuscular synaptic connections
Activity-dependent editing of neuromuscular synaptic connections

... branches during this time. These structural and functional observations suggested that multiple innervation is transiently maintained for a short period of time, during which there appears to be a relative balance of power among inputs that will end up competing for sole innervation of each neuromus ...
Introduction to Sense Organs
Introduction to Sense Organs

... General Properties of Receptors • transduction – the conversion of one form of energy to another – fundamental purpose of any sensory receptor – conversion of stimulus energy (light, heat, touch, sound, etc.) into nerve signals – sense organ, gasoline engine, light bulb are all transducers • recept ...
The Muscular System - MrTestaScienceClass
The Muscular System - MrTestaScienceClass

... Does not have bands ...
Neurotransmitter Release
Neurotransmitter Release

... only in the 20th century. It was embedded in a larger debate of whether neurons form a “reticular” network of connected cells, or a network of cells whose connections are discontinuous (the so-called neuron theory). Like with everything else in neuroscience, Ramón y Cajal is usually credited with t ...
Chapter 18 - Austin Community College
Chapter 18 - Austin Community College

... – How the brain receives taste information • Chemicals bind to receptors on microvilli-impulses generated • Gustatory (taste) cortex surveys incoming pattern of impulses • “Weighted average” is the perceived taste ...
CV-4-2014
CV-4-2014

... • Efferent nerves: cardiac sympathetic nerve, sympathetic constrictor nerve, vagus nerve • Effector: heart & blood vessels ...
A Ten Year Experience - Polio Outreach of Washington
A Ten Year Experience - Polio Outreach of Washington

... difficulties in any combination. It is this period of fever, weakness, paralysis, and muscle pain that many polio survivors (or their parents) remember. This was the time when infected motor neurons were dying, leaving all the muscle fibers they innervated orphaned (or denervated). If all the motor ...
Nervous System Notes
Nervous System Notes

... • These neurons “sense” your surroundings and send the message to your SPINAL CORD or BRAIN! They sense pressure or heat and ...
1 - Lone Star College
1 - Lone Star College

... Sense of Smell, cont 2. How the brain receives odor information a. Nerve fibers lead to the olfactory bulb b. Combinations of activated receptor proteins account for different odors c. An odor’s signature is determined by which neurons are stimulated in the olfactory bulb d. Neurons send signals th ...
ЛЕКЦІЯ 4
ЛЕКЦІЯ 4

... which provides automatic regulation of skeletal muscle length. When muscle lengthens, the spindle is stretched and the activity increases. This increases alpha motor neuron activity. Therefore the muscle contracts and the length decreases as a result. The gamma co-activation is important in this ref ...
The Nervous System
The Nervous System

... cell body - the cell body of the neuron; it contains the nucleus (also called the soma) dendrites - the branching structure of a neuron that receives messages (attached to the cell body) myelin sheath - the fatty substance that surrounds and protects some nerve fibers node of Ranvier - one of the ma ...
Class
Class

... synaptic transmission? a. synthesis, release, b. release, synthesis, c. binding, synthesis, d. synthesis, binding, ...
lower motor neurons
lower motor neurons

... • Motor neuron, its axon and the muscle fibers it innervates constitute the motor unit • Muscle fibers innervated by a single motor neuron can be only a few or up to 1000 • Delicate movements involve few motor units • Powerful movements involve many motor units ...
Lecture 19
Lecture 19

... The axons of small diameter are usually non-myelinated fibers, whereas the thicker axons have concentric wrappings of the enveloping cell to form the myelinated sheath. The fibers with myelinated sheaths are called myelinated fibers. Myelinated nerves, composed mainly of myelinated axons, appear wh ...
Gain-of-function mutation in Nav 1.7 in familial
Gain-of-function mutation in Nav 1.7 in familial

... for activation close to resting potential. Increased overlap between activation and steady-state inactivation for F1449V channels also increases the predicted window current. These changes each would be expected to lower the threshold of nociceptive DRG neurons which express mutant channels. Current ...
Ultrastructure and Function of Cephalopod Chromatophores
Ultrastructure and Function of Cephalopod Chromatophores

... what causes them? What is the nature of the innervation; is there evidence for more than one kind of nerve fiber—and where are the neuro-muscular junctions? What kinds of postsynaptic potentials are generated by stimulation of the nerve supply, and what are the effects of ACh and 5-HT on the muscle ...
p. A5 - Viktor`s Notes for the Neurosurgery Resident
p. A5 - Viktor`s Notes for the Neurosurgery Resident

... in denervated skeletal muscle, Acch receptors of fetal γ subunit-containing type appear over large portions of muscle membrane (normally, only endplate contains Acch receptors, and they are of adult ε subunit-containing type); these disappear and sensitivity returns to normal if nerve regrows (motor ...
Ch 48 Nervous System
Ch 48 Nervous System

... sheaths around the axons of many vertebrate ...
muscle strength testing gradation chart
muscle strength testing gradation chart

... 3. Herniations at lumbar disk levels do not usually affect the nerve exiting directly at that level because of the angle and position of exit of these nerves as they exit directly beneath the pedicle they essentially escape injury by the HNP. The nerve level that is usually affected is one level low ...
action potential — epilepsy
action potential — epilepsy

... many cortical neurons are excited simultaneously. What originally causes epilepsy is unknown. It is known that epilepsy can be related to damage to the CNS before, during, or just after birth; to head injuries that can occur at any age; to some poisons (including lead and alcohol); diseases (such as ...
Chapter 2 - IFSC-USP
Chapter 2 - IFSC-USP

... neuron are therefore said to be all-or-none, because they occur fully or not at all. If the amplitude or duration of the stimulus current is increased sufficiently, multiple action potentials occur, as can be seen in the responses to the three different current intensities shown in Figure 2.2B (righ ...
Motor Neurons
Motor Neurons

... branching terminal fibers, through which messages are sent to other neurons or to muscles or glands ...
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End-plate potential



End plate potentials (EPPs) are the depolarizations of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called ""end plates"" because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance. When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction. These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization. In the absence of an action potential, acetylcholine vesicles spontaneously leak into the neuromuscular junction and cause very small depolarizations in the postsynaptic membrane. This small response (~0.5mV) is called a miniature end plate potential (MEPP) and is generated by one acetylcholine-containing vesicle. It represents the smallest possible depolarization which can be induced in a muscle.
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