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Chapter 11
Chapter 11

... 1. Depolarization of Presynaptic Axon Terminal - When an action potential reaches the axon terminal, the influx of Na+ ions causes it to become depolarized 2. Depolarization Opens Voltage-Gated Ca++ Channels - In response the depolarization of the axon terminal, voltage-dependent Ca++ channels on pr ...
ANPS 019 Beneyto-Santonja 11-07
ANPS 019 Beneyto-Santonja 11-07

... skin for touch sensation) o Small receptive fields can discriminate finer sensations o When receptors synapse in spinal cord, many receptors converge; therefore, spinal cord neuron receptive fields are much more complex  Adapation – reduction in sensation with repeated stimulation; some receptors a ...
Acetylcholine Acetylcholine IUPAC name[hide] 2-Acetoxy
Acetylcholine Acetylcholine IUPAC name[hide] 2-Acetoxy

... activate non-specific cation conductances to directly excite neurons.[7] An effect upon postsynaptic M4muscarinic ACh receptors is to open inward-rectifier potassium ion channel(Kir) and cause inhibition.[8] The influence of acetylcholine on specific neuron types can be dependent upon the duration o ...
Excitable Cells and Action Potentials
Excitable Cells and Action Potentials

... In order for this process to occur, an active Na+ ion pump must do work breaking down ATP, thus these ion pumps are actually ‘ATPases’. These enzymes are also called Na+,K+-dependent ATPase, or ‘Na+/K+ Pump’. The concentration of Na+ is smaller on the inside of the cell, which is why the ATP is requ ...
Chapter Two Line Title Here and Chapter Title Here and Here
Chapter Two Line Title Here and Chapter Title Here and Here

... i. Axon terminals secrete neurotransmitters that either excite or inhibit other neurons or effector cells. ii. Axons may have a myelin sheath, a whitish, fatty, segmented covering that protects, insulates, and increases conduction velocity of axons. iii. Myelin sheaths in the PNS are formed by Schwa ...
Chapter Two Line Title Here and Chapter Title Here and Here
Chapter Two Line Title Here and Chapter Title Here and Here

... i. Axon terminals secrete neurotransmitters that either excite or inhibit other neurons or effector cells. ii. Axons may have a myelin sheath, a whitish, fatty, segmented covering that protects, insulates, and increases conduction velocity of axons. iii. Myelin sheaths in the PNS are formed by Schwa ...
Chapter 10
Chapter 10

... Motor end plate – 2 ACh bind – opens cation channel – Na+ influx – Membrane depolarized ...
The Nervous System
The Nervous System

... 2. Can neuroglia undergo action potentials? 3. The type of cell that carries nerve impulses in the nervous system is the ________________________. 4. The type of cell that nourishes, supports, and influences the activity of the neurons is the ________________. 5. The part of the neuron that brings i ...
Lecture Outline
Lecture Outline

... o This represents the movement of far fewer ions than would be required to alter the chemical concentration gradient. ...
Student Guide Chapter 11
Student Guide Chapter 11

... chemicals other than neurotransmitters modify neuronal activity. V. Neurotransmitters and Their Receptors (pp. 414–421; Figs. 11.20–11.21; Table 11.3) A. Neurotransmitters fall into several chemical classes: acetylcholine, the biogenic amines, amino acid derived, peptides, purines, and gases and lip ...
Nervous System Notes
Nervous System Notes

... negative to positive. Causes neurotransmitters(chemicals) to be released at the terminal, to stimulate the next neuron in the chain. ...
Slides - gserianne.com
Slides - gserianne.com

... resting potential, it has depolarized (Movement of ? charges causes this?) • A membrane returning to its resting potential from a depolarized state is being repolarized (Movement of ? charges causes this?) • If membrane potential becomes more negative than its resting potential, it has hyperpolarize ...
Chapter_Twenty_1_
Chapter_Twenty_1_

... The enzyme adenylate cyclase transfers the message to a second messenger, a cyclic adenosine monophosphate (cyclic AMP), that acts within the target cell. • Neurotransmitters are synthesized in presynaptic neurons and stored there in vesicles from which they are released when needed. They travel acr ...
Lecture12 PPT
Lecture12 PPT

... • An action potential is an all-or-none response; that is, it either occurs to its full extent or does not occur at all. ...
Your Name Here______________________________
Your Name Here______________________________

... 9. The nerve impulse conduction occurring along myelinated nerve fibers is called a. somatic transmission b. visceral conduction c. synaptic transmission d. saltatory conduction 10. A group of neuronal cell bodies (cytons) in the PNS is called a a. nucleus b. tract c. ganglion d. nerve e. nerve fibe ...
chapter3Weiten
chapter3Weiten

... Electrically charged particles (ions) Neuron at rest – negative charge on inside compared to outside -70 millivolts – resting potential ...
Neurons, Synapses, and Signaling
Neurons, Synapses, and Signaling

... o This represents the movement of far fewer ions than would be required to alter the chemical concentration gradient. ...
The Biological Bases of Behavior
The Biological Bases of Behavior

... – Electrically charged particles (ions) – Neuron at rest – negative charge on inside compared to outside – -70 millivolts – resting potential ...
Nervous System - Academic Computer Center
Nervous System - Academic Computer Center

... Neurotransmitter effects are terminated in three ways: degradation by enzymes from the postsynaptic cell or within the synaptic cleft; reuptake by astrocytes or the presynaptic cell; or diffusion away from the synapse. ...
LESSON 3.3 WORKBOOK
LESSON 3.3 WORKBOOK

... We can see this circuit in action when we bang our elbow or stub our toe, and then immediately go to rub it. By rubbing the painful area we’re applying pressure that will activate our pressure-sensitive neurons. These neurons will then communicate with the projection neurons in the spinal cord and i ...
Chapter 8
Chapter 8

... Two overlapping graded depolarizations demonstrate temporal summation. Distinct actions of stimulating neurons A and B demonstrate spatial summation. A and B are stimulated enough to cause a suprathreshold graded depolarization, so an action potential results. Neuron C causes a graded hyperpolarizat ...
a14a NeuroPhysI
a14a NeuroPhysI

...  Threshold stimulus—strong enough to push the membrane potential toward and beyond threshold (Membrane is depolarized by 15 to 20 mV)  AP is an all-or-none phenomenon—action potentials either happen completely, or not at all  All action potentials are alike and are independent of stimulus intensi ...
Stochastic fluctuations of the synaptic function
Stochastic fluctuations of the synaptic function

... synapses produced quantal Excitatory PostSynaptic Currents (EPSCs) with peak amplitudes having a 5-65 pA range. The histogram of the peak amplitudes showed a long right tail. If the variability of the postsynaptic response observed in hippocampal neurons should be extended to all the neurons of brai ...
Chapter 2: Neuroscience
Chapter 2: Neuroscience

... Consider MS – the myelin sheath breaks down and results in slow communication to the muscles. ...
No Slide Title
No Slide Title

... - Chemicals from other neurons - Chemicals from endocrine glands - Chemicals from outside sources (e.g., Drugs) ...
< 1 ... 127 128 129 130 131 132 133 134 135 ... 167 >

End-plate potential



End plate potentials (EPPs) are the depolarizations of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called ""end plates"" because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance. When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction. These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization. In the absence of an action potential, acetylcholine vesicles spontaneously leak into the neuromuscular junction and cause very small depolarizations in the postsynaptic membrane. This small response (~0.5mV) is called a miniature end plate potential (MEPP) and is generated by one acetylcholine-containing vesicle. It represents the smallest possible depolarization which can be induced in a muscle.
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