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You and Your Brain ppt - Oregon School District
You and Your Brain ppt - Oregon School District

... In 1973, scientists discovered that the brain had receptors for opiates. Or you can spell it by its chemical In other words, there are places on name: diacetylmorphine. neurons that recognize opiates. These receptors were located in parts of the brain important for breathing, pain and emotions. The ...
LYRICA (pregabalin) eLearning System
LYRICA (pregabalin) eLearning System

... The nervous system is central to a myriad of complex, interrelated functions, including thought, mood, perception of pain and other sensory input, regulation of sleep, and control of movement. The interactions among the functional components of the nervous system are central to its effective functio ...
Implications of Altered Brain Ganglioside Profiles in Amyotrophic
Implications of Altered Brain Ganglioside Profiles in Amyotrophic

... ganglioside patterns are affecting receptors for growth factors or neurotrophic hormones that are essential for the maintenance of motor neurons. Within recent years, attention has focused on growth factors and their receptors in the plasma membranes of all cells including neurons and their roles in ...
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PDF file

... prioritizes three types of information with decreasing urgency: (1) punishment, (2) reward, and (3) novelty. As punishment and rewards are typically sparse in time, novelty can provide temporally dense motivation even during early life. Krichmar 2008 [11] provided a survey that includes five types o ...
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L3-ANS LECTURE Sulta..

... 3 “Decreases” decreased HR, diameter of airways and diameter of pupil • Paradoxical fear when there is no escape route or no way to win causes massive activation of parasympathetic division loss of control over urination and defecation ...
Neuronal Loss in the Brainstem and Cerebellum
Neuronal Loss in the Brainstem and Cerebellum

... shown that different parts of the human brain are affected differently by aging (1,2) and that phylogenetically younger parts of the brain such as the cerebral and cerebellar cortex are more likely to undergo morphological changes (3) than do the phylogenetically older subcortical structures. It has ...
presentation source
presentation source

... Many enzymes have sites for cations, such as Ca2+ and Zn2+. Other cations, such as K+ and Na+, have weak but significant affinity for the same sites. [K+]i and [Na+]i >> [Ca2+]i and [Zn2+]i. Organic solutes are neutral or zwitterionic and do not interfere with enzymes. ...
Descending Spinal Tracts
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... The Basal Ganglia • The Motor Loop (Cont’d) – Basal Ganglia Disorders • Hypokinesia and hyperkinesia • Parkinson’s disease – Symptoms: Bradykinesia, akinesia, rigidity and tremors of hand and jaw – Organic basis: Degeneration of substantia nigra inputs to striatum – Dopa treatment: Facilitates produ ...
Neural Cognitive Modelling: A Biologically Constrained Spiking
Neural Cognitive Modelling: A Biologically Constrained Spiking

... neuron fires, resetting the voltage to zero for a refractory period. When a neuron fires, it releases current to all connected neurons. This post-synaptic current decays exponentially over time at a rate τ that depends on the neurotransmitter and receptors involved (ranging from two to hundreds of m ...
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Spiking Neurons with Boltzmann-like Properties to

... with neural systems, learning is merely the change of connection strengths, which are biologically synaptic strengths; with Hebbian learning, the strengths are changed based solely on the properties of the pre and and post-synaptic neurons. This is typically the firing behaviour of these neurons, an ...
Design Features in Vertebrate Sensory Systems
Design Features in Vertebrate Sensory Systems

... tations of the lateral line receptor sheet, Central representations of variables of this one each for ordinary lateral line receptors sort would have to differ from the examples discussed in the previous section: they and electroreceptors (Knudsen, 1977). A third property of sensory structures is wo ...
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The Journal of Neuroscience, June 1, 2003 • 23(11):4657– 4666
The Journal of Neuroscience, June 1, 2003 • 23(11):4657– 4666

... Ilan A. Kerman1,2,3 Lynn W. Enquist,4 Stanley J. Watson,3 and Bill J. Yates Previous physiological investigations have suggested the existence of a neural circuit that coordinates activation of motor and autonomic efferents before or at the onset of exercise. Traditionally these circuits have been p ...
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TRUTH Read

... much smaller. It is involved in balance and coordi rianon. A person whose cerebellum is injured may have trouble with coordination. [he person may walk unevenly and even occasionally fail doivn. [he midbrain is located between the hindbrain and the forebrain Areas within the midbrain are involi ed i ...
Electrical membrane properties of rat subthalamic neurons in an in
Electrical membrane properties of rat subthalamic neurons in an in

... Injections of depolarizing current pulses to STH neurons produced either repetitive or burst discharges. The duration of action potentials was about 1 ms. When neurons with a membrane potential of 40-65 mV were activated by the rejection of current pulses, single or repetitive action potentials were ...
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... Many students have encountered the material in this unit before, either in biology or in high school psychology. The trick, then, is to make this material clear but also different enough in orientation from what they have learned earlier so that it will engage their interest. To the extent that you ...
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Principles of Extracellular Single

... with behaviors or physiological events. Electrical or chemical stimulation of identified cell populations at the recording site can also be used to determine the effects of cell activity on behavior or physiology. As with any methodology, there are limits to the kinds of questions that can be addres ...
Comparative Models of GABAA Receptor
Comparative Models of GABAA Receptor

... Fig. 1. Alignment of nACh and GABAA receptor helical domains. a, a subset of a superfamily alignment of the four segments that make up the helical (transmembrane) domain of the subunit chains is shown. The position of the missing “cytoplasmic loop” between helices 3 and 4 is indicated by a double-ga ...
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... • Input comes from exteroceptors, proprioceptors, and interoceptors • The three main levels of neural integration in the somatosensory system are: • Receptor level – the sensor receptors • Circuit level – ascending pathways ...
Amyloid cascade hypothesis
Amyloid cascade hypothesis

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Excitation of Ventral Tegmental Area Dopaminergic and
Excitation of Ventral Tegmental Area Dopaminergic and

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(See Page 85) The

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Jessica Sallander The mechanism of G protein coupled receptor

... proteins both, integral and peripheral are embedded. Protein content varies greatly among the different kinds of membranes, ranging typically between 15-75% depending on the functions that they must carry out2. Furthermore, lipid composition changes from one membrane to another, due to enormous stru ...
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Nucleus Accumbens Medium Spiny Neurons Target Non

... containing ChR2–tdtomato (AAV2/1 CAG::ChR2.tdtomato, a kind gift from Karel Svoboda) was bilaterally injected (1 ␮l in each side) using a Hamilton syringe stereotaxically placed into the NAc shell (anteroposterior, ⫹1.5 mm from bregma; mediolateral, ⫾0.8 mm from bregma; ventral, ⫺6.7 mm from skull s ...
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Molecular neuroscience



Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject primarily pertains to a reductionist view of neuroscience, considering topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics on neuronal development, and the molecular basis for neuroplasticity and neurodegenerative diseases. As with molecular biology, molecular neuroscience is a relatively new field that is considerably dynamic.
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