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Down - 서울대 Biointelligence lab
Down - 서울대 Biointelligence lab

... without task-relevant characteristics with an average firing rate of about 15 spikes/s. The coefficient of variation of the spike trains is Cv ≈ 1.09. (B) Simulated data from a Poisson distributed spike trains I which a Gaussian refractory time has been included. The solid line represents the probab ...
(1996). "A multi-threshold neural network for frequency estimation,"
(1996). "A multi-threshold neural network for frequency estimation,"

... Human perception of sound arises from the transmission of action-potentials (APs) through a neural network consisting of the auditory nerve and elements of the brain. Analysis of the response properties of individual neurons provides information regarding how features of sounds are coded in their r ...
Memory fields of neurons in the primate prefrontal cortex
Memory fields of neurons in the primate prefrontal cortex

... certain visual field locations. Note that even when neurons had relatively large MFs, they often had ‘‘hot spots,’’ MF subregions that elicited more delay activity than other regions (Fig. 2c). Thus, they could convey spatial information even within their MFs. Neuronal properties are summarized in T ...
SENSE AND THE SINGLE NEURON: Probing the Physiology of
SENSE AND THE SINGLE NEURON: Probing the Physiology of

... can perform the same role for this review. Figure 1A shows the performance of a human observer detecting weak flashes of light against a completely dark background (Hecht et al 1942). The probability of correctly detecting the flash is plotted on the ordinate, and the log intensity of the flash is p ...
Computational Psychiatry Seminar: Spring 2014 Week 11: The
Computational Psychiatry Seminar: Spring 2014 Week 11: The

... Gabor Stefanics (TNU) ...
Simulating Populations of Neurons - Leeds VLE
Simulating Populations of Neurons - Leeds VLE

... Figure 2 Brodmann areas of the brain (Gazzaniga, 1998) ...................................................................... 9 Figure 3 Types of biological neurons in the nervous system (Gazzaniga, 1998) .................................. 10 Figure 4 Anatomy and Functional areas of the brain (http: ...
Synaptic reverberation underlying mnemonic persistent activity
Synaptic reverberation underlying mnemonic persistent activity

... location or eye position), in terms of continuous ‘bump attractors’ and ‘line attractors’. This review summarizes new studies, and discusses insights and predictions from biophysically based models. The stability of a working memory network is recognized as a serious problem; stability can be achiev ...
Progress Report – Glover
Progress Report – Glover

... With the anatomical mapping already in hand, it is feasible to begin asking questions about the genetic regulation of neuronal type specification. As a first step, it is important to determine which transcription factors are expressed in or near specific identified neurons. To this end, Søviknes has ...
Voltage-Gated Ion Channels and the Propagation of Action
Voltage-Gated Ion Channels and the Propagation of Action

... meter long, yet it takes only a few milliseconds for an action potential to move along their length. Arrival of an action potential at an axon terminal leads to opening of voltagesensitive Ca2 channels and an influx of Ca2, causing a localized rise in the cytosolic Ca2 concentration in the axon t ...
C. elegans Neurology Supplement - Bio-Rad
C. elegans Neurology Supplement - Bio-Rad

... remains to be learned. One of the major gaps in our knowledge lies in our lack of understanding of how the human brain functions. The brain is the most complex organ in the human body and arguably the most remarkable, yet very basic questions remain unanswered. How does the human brain store memorie ...
Faithful Expression of Multiple Proteins via 2A
Faithful Expression of Multiple Proteins via 2A

... sequences was synthesized and subcloned between BamHI and AgeI sites of plasmid pAAV6P-SEWB (Shevtsova et al., 2005). The iCre gene sequence (Shimshek et al., 2002) was cloned between the synapsin promoter and the 2A peptide sequence to generate pAAV-SyniCre2A-EGFP. The pAAV-CMV-iCre2AEGFP was const ...
ARTICLE  IN  PRESS Neural Networks entorhinal cortex
ARTICLE IN PRESS Neural Networks entorhinal cortex

... angle will be proportional to the magnitude and duration of the encoded input. Experimental data from stellate cells shows differences in the oscillation frequency observed in different individual cells recorded at different membrane potentials in dorsal entorhinal cortex (Giocomo & Hasselmo, 2008a) ...
HIERARCHICAL MODELS OF VARIANCE SOURCES Harri Valpola
HIERARCHICAL MODELS OF VARIANCE SOURCES Harri Valpola

... changes in the mean of different quantities while variances are assumed constant. This assumption is often known to be invalid but suitable techniques for jointly estimating both means and variances have been lacking. The basic problem is that if the mean is modelled by a latent variable model such ...
A dendritic disinhibitory circuit mechanism for pathway
A dendritic disinhibitory circuit mechanism for pathway

... Output rate (Hz) ...
Optogenetics Review1 - Department Of Biological Sciences
Optogenetics Review1 - Department Of Biological Sciences

... electrical field stimulation is simple, convenient and has high temporal resolution, the electrical field is generally non-uniform and many untargeted neurons are stimulated simultaneously. It is thus difficult to identify which neurons are stimulated. On the other hand, a single, identified neuron ...
Intracellular and computational evidence for a
Intracellular and computational evidence for a

... The first proposal that neurons are not passive relays being driven by external inputs dates back to the early 20th century with the Belgian electrophysiologist Frederic Bremer [16, 17]. He proposed that neurons generate intrinsic and self-sustained activity under the form of intrinsic oscillatory p ...
Ionic Mechanism of the Slow Afterdepolarization Induced by
Ionic Mechanism of the Slow Afterdepolarization Induced by

... 1998. The mammalian prefrontal cortex receives a dense cholinergic innervation from subcortical regions. We previously have shown that cholinergic stimulation of layer V pyramidal neurons of the rat prefrontal cortex results in a depolarization and the appearance of a slow afterdepolarization (sADP) ...
What We Can and What We Can`t Do with fMRI
What We Can and What We Can`t Do with fMRI

... striosomes of basal ganglia, one must know a great deal about synapses, neurons, and their interconnections. In the same way, to understand the functioning of a distributed large-scale system, such as that underlying our memory or linguistic capacities, one must first understand the architectural un ...
(Full text - MSWord file 171K)
(Full text - MSWord file 171K)

... patterns (e.g., Berns & Sejnowski, 1998). The second class focuses on the tonic inhibitory activity that the major basal ganglia output nuclei exert upon their targets, assuming that it provides for action selection via focused disinhibition (e.g., Gurney et al., 2001). In this paper, we focus on th ...
High-speed CCD movie camera with random pixel selection,
High-speed CCD movie camera with random pixel selection,

... Laser-scanning systems for voltage-sensitive dye recording have been developed by two groups (Morad et al., 1986; Saggau, 1994). These employ acousto-optic deflectors to rapidly steer a laser excitation spot to user- selectable regions in the specimen. Fluorescence is detected by a single photodiode ...
Directionally Selective Complex Cells and the Computation of
Directionally Selective Complex Cells and the Computation of

... was 0.4. Responses were sampled in 16 periodic increments in time, t, beginning with the time of stimulus Cortical 1-bar tests presentation, and also 16 samples in one-dimensional To study DS we began by reducing the stepwise (1D) space. The number of samples plotted was chosen movement sequence to ...
Functional maps within a single neuron
Functional maps within a single neuron

... Functional maps across neurons constitute a common design principle in various regions of the central nervous system. These topographic maps are systematic and continuous spatial representations of information within a brain region, where adjacent neurons represent adjacent points along a parametric ...
The Nervous System
The Nervous System

... bring information to the cell body. There can be many dendrites, with the branches providing many avenues for incoming impulses. The single axon routes the nerve impulse from the cell body to another neuron or an effector organ. The axon can have terminal branches, so each time the nerve fires, it c ...
Spike-Timing Theory of Working Memory
Spike-Timing Theory of Working Memory

... cognitive tasks, such as language comprehension, learning, and reasoning. Despite extensive neuroscience research, its mechanism is not clearly understood. We exploit a well-known feature of the brain — its ability to use precisely timed spiking events in its operation — to show how working memory f ...
and Third-Order Neurons of Cockroach Ocelli
and Third-Order Neurons of Cockroach Ocelli

... responses are essentially linear. Second-order neurons o f a variety of visual systems also generate essentially linear responses. This is the case in vertebrate retinas (Naka et al., 1979; Tranchina et al., 1983; Chappell et al., 1985), in Limulus lateral eyes (Knight et al., 1970), in insect compo ...
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Biological neuron model

A biological neuron model (also known as spiking neuron model) is a mathematical description of the properties of nerve cells, or neurons, that is designed to accurately describe and predict biological processes. This is in contrast to the artificial neuron, which aims for computational effectiveness, although these goals sometimes overlap.
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