• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Introduction
Introduction

... •Contain 3 functional specializations: (a) sensory areas which direct perception; (b) motor areas which direct movement; (c) associated areas which integrate information and direct voluntary areas. ...
Neuroscience and Behavior
Neuroscience and Behavior

... and had developed problems with peripheral vision. I went to my optometrist and he referred me to an ophthalmologist who tested my visual field acuity and found there was a severe problem on both sides of my periphery. So, several more tests were run, and he thought I was either going blind from the ...
The Nervous System WS-11A Review Quest
The Nervous System WS-11A Review Quest

... 2. What are the two primary cells of the nervous system, and what do they do? The two primary cells of the nervous system are neurons, that actually carry and store information, and glial cells that support the neurons. 3. What protects the brain? The brain is protected by the bones of the skull and ...
Functional imaging of hippocampal palace cells at celluar resolution
Functional imaging of hippocampal palace cells at celluar resolution

... (a) The place cells are colored according to the location of their place fields along the virtual linear track. Example place cells with different place fields depending on the running direction are highlighted with closed arrowheads (b) A plot of mean ΔF/F versus linear track position for the posit ...
Supporting Cells of the Nervous System
Supporting Cells of the Nervous System

... 2) act as phagocytes to clean up worn-out neuron organelles. 3) Electrically insulate neurons by forming a myelin sheath. 4) increase the speed of the action potential (electrochemical message) in those cells that have a myelin sheath. ...
The Nervous System
The Nervous System

... Interesting Facts about the Neuron • Longevity – can live and function for a lifetime • Do not divide – fetal neurons lose their ability to undergo mitosis; neural stem cells are an exception • High metabolic rate – require abundant oxygen and glucose ...
Overview and Integration
Overview and Integration

... Composite radioisotope brain scan for patients with each type of aphasia. Darker regions indicate areas where the lesions of many individual patients overlap. The isotope scans operate on the principle that the labeled compound can cross the blood-brain barrier in damaged tissue but not in healthy c ...
Discover Biologists Find Chemical Behind Cancer Resistance
Discover Biologists Find Chemical Behind Cancer Resistance

... The complex network of waste removal—which researchers have dubbed the glymphatic system—was first disclosed by Nedergaard and colleagues last August in the journal Science Translational Medicine. The key to discovering and understanding the system was the advent of a new imaging technology called t ...
File
File

... a series of weak stimuli trigger enough neurotransmitter to fire an impulse ...
Organization and Development of the Nervous System
Organization and Development of the Nervous System

... (both voluntary and automatic control) ...
Design a Neuron
Design a Neuron

... Axon terminals – release the electrical impulse as a chemical called a neurotransmitter into the synapse to the next neuron or organ. ...
Dopamine axons of substantia nigra pars compacta neurons and
Dopamine axons of substantia nigra pars compacta neurons and

... membrane potential of rat SNc DA neurons, ventral tegmental area DA neurons which are less vulnerable in PD and human SNc DA neurons which are 10 times more complex than in the rat. We implemented a compartmental model of the DA neurons with synthetically reconstructed axon arbourisations. After the ...
Structure of the Nervous System
Structure of the Nervous System

... •Contain 3 functional specializations: (a) sensory areas which direct perception; (b) motor areas which direct movement; (c) associated areas which integrate information and direct voluntary areas. ...
The Brain: It`s All In Your Mind
The Brain: It`s All In Your Mind

... Anatomy of a basic neuron: Neurons are comprised of three major parts – Dendrites, Cell Body, and Axon. See Figure 2 Neuron, next page. Most neurons have a series of branching extensions called dendrites. They look something like small tree branches. Dendrites extend out from the cell body. These de ...
Chapter 12-13 Summary
Chapter 12-13 Summary

... pump. (Review NAP handout and Figures 12.10 - 12.11) ...
2016-2017_1stSemester_Exam1_050117_final
2016-2017_1stSemester_Exam1_050117_final

... The spinal center of the reflex arc is formed by ………………………………………….. that communicate with ………………………... (functional type) muscles on the side of the stimulus. The compensatory action on the contra-lateral side involves the simultaneous contraction of the ………………… ………………groups. Identify the labeled str ...
consciousness
consciousness

... • between conscious and unconscious elements of memory • between forms of brain damage that selectively impair conscious process and those that don’t • between wakefulness and unconsciousness • between new and habituated events ...
9.01 - Neuroscience & Behavior Fall 2003 Massachusetts Institute of Technology
9.01 - Neuroscience & Behavior Fall 2003 Massachusetts Institute of Technology

... to predatory aggression is not due to increased hunger? 6) Describe an experiment that indicates connections to the motor system by the hypothalamic neurons involved in attack behavior. 7) How critical is the hypothalamus for control of attack behavior in the cat? Or, for temperature regulation? 8) ...
LSUHSC N C E
LSUHSC N C E

... Connections in the adult CNS are highly precise. In the visual system, retinal ganglion cells connect to target LGN neurons in adjacent, non-overlapping eye-specific layers. During development, retinal inputs are intermixed and the layers emerge as axons from the two eyes remodel. Remodeling require ...
Lecture-24-2012-Bi
Lecture-24-2012-Bi

... nicotinic receptors (pharmacological deep brain stimulation) 2. Presynaptic: Selective upregulation in nerve terminals of dopaminergic neurons 3. Cell-delimited: Pharmacological chaperoning of intracellular receptors → reprogram cell physiology ...
Chapter 3
Chapter 3

... from donors into the damaged area.  Human research - Parkinson’s disease patients have partial recovery of motor ability from transplanted fetal tissue.  Ethics - a major debate over the use fetal stem cells exists, acceptance might be higher for adult stem cell use ...
formalin as a peripheral noxious stimulus causes a biphasic
formalin as a peripheral noxious stimulus causes a biphasic

... 60 minutes post formalin injection (n=4). As shown in this figure, the activity of the LPGi neurons exhibit a first peak, ...
Neural Crest
Neural Crest

... crest cells separate from the neural epithelium via an epithelial-mesenchymal transformation. We present three models to account for this process: • (1) separation by asymmetric mitosis, • (2) separation by generating tractional force in order to rupture cell adhesions • (3) loss of expression or fu ...
The First Open International Symposium
The First Open International Symposium

... Then, how is the spatial gradient detected in klinotaxis? Because worms sense chemicals at one point at the anterior end of the body, comparison between two sensors is unlikely. By stimulating the sensory neuron by using chanelrhodopsin in synchrony with head swing, it was suggested that spatial gra ...
big
big

... Neurons and Glia are the two major cell types that make up the nervous system Neurons transmit messages from cell to cell – Sensory neurons transform stimuli (e.g. light, sound, or joint position) into messages sent to other neurons – Interneurons integrate information from many cells; particular in ...
< 1 ... 441 442 443 444 445 446 447 448 449 ... 467 >

Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report