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Nervous system Nervous system
Nervous system Nervous system

... • Nervous tissue consists of neurons; whereas the brain and spinal cord contain all parts of neurons, nerves contain only axons. ...
THE CEREBRAL CORTEX
THE CEREBRAL CORTEX

... Nc. basalis (Meynert)-cholinergic system Raphe nuclei (serotonin) Locus coeruleus (noradrenalin) Subst. Nigra (VTA) - dopamin ...
Nervous Tissue
Nervous Tissue

... transmission rate of nerve impulses ...
Central Nervous System
Central Nervous System

... − Structural & functional part of nervous system − Specialized functions • Neuroglia (glial cells) − Support & protection of nervous system Neurons • Function • Conduct electrical impulses • Structure • Cell body − Nucleus with nucleolus − Cytoplasm • Cytoplasmic processes − Dendrites − Axon  Basic ...
TSM34 - Chemical Senses
TSM34 - Chemical Senses

...  Large supporting cells with apical microvilli separate individual olfactory cells  Smaller basal cells allow passage of multiple axons through gaps in the plate o Each cell has a single descending neurite to the mucosa into which olfactory cilia project  The actual ‘receptive units’ are containe ...
- Thomson One
- Thomson One

... http://www.worldometers.info/world-population/ Accessed March 2015. http://faculty.stcc.edu/AandP/AP/AP1pages/nervssys/unit10/neurons.htm Accessed March 2015. ...
Somatic nervous system
Somatic nervous system

... corticospinal tract, via axons to control skeletal (voluntary) muscles. These stimuli are conveyed from upper motor neurons through the ventral horn of the spinal cord, and across synapses to be received by the sensory receptors of alpha motor neuron (large lower motor neurons) of the brainstem and ...
The Nervous System
The Nervous System

... • Damage to sections of the spinal cord can result in paralysis. • Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is caused by motor neurons in the brain and spinal cord dying. This eventually leads to paralysis and patients cannot ...
MBBC Junior Neuroscience E-Book v1
MBBC Junior Neuroscience E-Book v1

... AMYGDALA - A structure in the forebrain that is an important component of the limbic system and plays a central role in emotional learning, particularly within the context of fear. APHASIA - Disturbance in language comprehension or production, often as a result of a stroke. AUTONOMIC NERVOUS SYSTEM ...
Single Neurons
Single Neurons

... timed against the local field potential (LFP) – the ‘coordinated action-potential timing across populations of neurons’. The LFP is the favoured inducer of synaptic plasticity, and synaptic plasticity is thought to underlie memory formation. ...
Understanding the Interactions and Effects of
Understanding the Interactions and Effects of

... Protease activated receptor-1 (PAR-1) is part of a family of receptors that use thrombin as the signaling protein. PAR-1 has already been shown to lead to apoptosis of motor neurons found in the spinal cord, although the specific mechanism of cell death is not completely understood. While motor neur ...
notes as
notes as

... and bind to receptor molecules in the membrane of the postsynaptic neuron thus changing their shape. – This opens up holes that allow specific ions in or out. • The effectiveness of the synapse can be changed – vary the number of vesicles of transmitter – vary the number of receptor molecules. • Syn ...
house symposium 2015 - Instituto do Cérebro
house symposium 2015 - Instituto do Cérebro

... Animals respond differently to stress. While some individuals are able to overcome the stressor (resilience), others may develop depression or post- traumatic stress disorder. Several lines of evidence suggest a link between behavioral phenotype and long-term plasticity in the classic brain reward c ...
Nervous System
Nervous System

...  Magnetic Resonance Imaging (MRI) (shows a high resolution of soft tissue and does not involve an x-ray) ...
Ascending Projections
Ascending Projections

... • Autonomic responses and visceral sensations accompany most emotion. The earliest theory hypothesized that emotion is the result of basic sensations: – Aristotle (350 BCE) - pain is an emotion – James-Lange (1884-85) – emotions result from physical changes - “we feel sorry because we cry, ... afrai ...
Chapter 7
Chapter 7

... – Carries electrical impulse away from cell body – May be covered by Schwann cells • Forms discontinuous myelin sheath along length of axon ...
Neuronal cell types
Neuronal cell types

... (A) Projection neurons; (B) intrinsic neurons. The projection neurons of the cortex are pyramidal cells, and the intrinsic cells are simply called interneurons. The projection neuron of the cerebellum is the Purkinje cell, and the intrinsic cells are the granule, basket, stellate and Golgi cells. Th ...
Hypothalamus
Hypothalamus

... • Target neurons – Preganglionic neurons in spinal cord ...
Biological Basis of Behavior
Biological Basis of Behavior

... A chemical messenger that travels across the synapse from one neuron to the next Can influence whether the second neuron will generate an action potential or not Researchers have discovered hundreds of substances known to function as neurotransmitters …they help promote sleep, alertness, learning an ...
The Nervous System
The Nervous System

... of the nervous system • Specialized to conduct information from one part of the body to another • There are many, many different types of neurons but most have certain structural and functional characteristics in common: - Cell body (soma) - One or more specialized, slender processes (axons/dendrite ...
Worksheet - Humble ISD
Worksheet - Humble ISD

... There are 3 types of neurons, they are _______________, ______________, & _______________. The ______________ neuron carries impulses from the brain to muscles or glands. The _________________ neuron connects the other two types together. Lastly, the ____________ neuron carries impulses from sense o ...
Chapter 3
Chapter 3

... cell splits into 2 identical new founder cells – The second phase is called asymmetrical division, because the divide into a new founder cell and a neuron, which migrates away (this lasts about 3 months) ...
Which of the following statements is FALSE regarding glial
Which of the following statements is FALSE regarding glial

... b) The neuron is negatively charged while the extra-cellular medium is positively charged c) The neuron predominantly contains negatively charged ions while the extra-cellular medium contains positively charged ...
Linear associator
Linear associator

... trials. Remove input from two of the presynaptic neurons and from all of the postsynaptic neurons. Insert stimuli into two different presynaptic neurons (so that five are active again) and insert stimuli into four different postsynaptic neurons. Again, run four trials. Remove the inputs from the pos ...
Modeling the Evolution of Decision Rules in the Human Brain
Modeling the Evolution of Decision Rules in the Human Brain

... (Levine, Mills, & Estrada, IJCNN2005). Changes that affect behavior (“do” and “don’t” instructions, approach toward or avoidance of an object) are likely to be at connections from amygdala to medial prefrontal cortex (incentive motivation) and from orbitofrontal to nucleus accumbens (habit). ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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