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Fundamentals of the Nervous System and Nervous Tissue: Part A
Fundamentals of the Nervous System and Nervous Tissue: Part A

... • Long axons (nerve fibers) • Occasional branches (axon collaterals) The Axon • Numerous terminal branches (telodendria) • Knoblike axon terminals (synaptic knobs or boutons) • Secretory region of neuron • Release neurotransmitters to excite or inhibit other cells ...
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CHAPTER 11 Nervous Tissue - Austin Community College
CHAPTER 11 Nervous Tissue - Austin Community College

... Synapse – site where two nerves communicate with each other. Presynaptic neuron – neuron that is conducting information toward the next neuron Postsynaptic neuron – transmits information away from synapse Most synaptic communication is via chemical messengers (e.g. acetylcholine, serotonin, norepine ...
Chapter 28: Nervous System
Chapter 28: Nervous System

... 3. Motor Output: Conduction of signals from brain or spinal cord to effector organs (muscles or glands). Controls the activity of muscles and glands, and allows the animal to respond to its ...
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Comparative approaches to cortical microcircuits
Comparative approaches to cortical microcircuits

... all appear to exist in both rats and bats [36,37], even though place fields are 2-dimensional in rats and 3-dimensional in flying bats. Interesting inter-species differences occur, however, in the collective neural dynamics that accompany these mapping properties. Whereas highfrequency ripple oscill ...
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PSB 4002 - Developmental Psychobiology Laboratory

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... Friday, December 3: 3:30-4:30 Thursday, December 9: 10:00-12:00, 1:00-3:00 Friday, December 10: 10:00-1:00 ...
Neuron PowerPoint
Neuron PowerPoint

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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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