
Mechanisms of Perception: Hearing, Touch, Smell, Taste & Attention
... Smell & taste are highly integrated ...
... Smell & taste are highly integrated ...
signals in a storm - Columbia University
... might see when one brain cell communicates reconstruction, four years in the making, of a miwith another across a synapse—the point of nuscule cube of nervous tissue in a rat brain. contact between two nerve cells. How the brain Aside from showing structure, it captures a sinsenses, thinks, learns a ...
... might see when one brain cell communicates reconstruction, four years in the making, of a miwith another across a synapse—the point of nuscule cube of nervous tissue in a rat brain. contact between two nerve cells. How the brain Aside from showing structure, it captures a sinsenses, thinks, learns a ...
A zebrafish model exemplifies the long preclinical period of motor
... the zebrafish provides an excellent model system to study motor neuron disease.2 Additionally, the transparency and ex vivo development of embryos enables one to trace early embryonic changes in disease pathogenesis. As a follow-up to the original study, our further studies have established that the ...
... the zebrafish provides an excellent model system to study motor neuron disease.2 Additionally, the transparency and ex vivo development of embryos enables one to trace early embryonic changes in disease pathogenesis. As a follow-up to the original study, our further studies have established that the ...
Central Auditory Pathways
... Neuron specialization The three major types of neurons, depending on their specialization: Sensory Neurons Motor Neurons Interneurons ...
... Neuron specialization The three major types of neurons, depending on their specialization: Sensory Neurons Motor Neurons Interneurons ...
MPG-official form - Max Planck Institute for Chemical Ecology
... Modern functional imaging methods show that these sensory perceptions cause certain response patterns in the brain: Depending on the processed information, specific brain areas are activated. If an odor is rated as pleasant or disgusting, this classification method is called “hedonic valence.” Studi ...
... Modern functional imaging methods show that these sensory perceptions cause certain response patterns in the brain: Depending on the processed information, specific brain areas are activated. If an odor is rated as pleasant or disgusting, this classification method is called “hedonic valence.” Studi ...
LECTURE18.Olfaction&Taste
... Apical dendrite of sensory neuron projects through support cells to nasal cavity, and is capped by dendritic cilia projecting into specialized mucus in the cavity Olfactory sensory neurons are fairly short-lived (1-2 months), and regenerate from basal stem cells Each sensory neuron responds to a sin ...
... Apical dendrite of sensory neuron projects through support cells to nasal cavity, and is capped by dendritic cilia projecting into specialized mucus in the cavity Olfactory sensory neurons are fairly short-lived (1-2 months), and regenerate from basal stem cells Each sensory neuron responds to a sin ...
OUTLINE FORMAT-Unit 3A Biological Basis of Behavior Directions
... Include the definitions, functions, shape (when noted) and locations (when applicable) of each of the terms. Highlight each term: 5. Answer this: What functions are served by the various cerebral cortex regions? Structure of the Cortex: 6. Describe the “look” of the vertebral cortex. ...
... Include the definitions, functions, shape (when noted) and locations (when applicable) of each of the terms. Highlight each term: 5. Answer this: What functions are served by the various cerebral cortex regions? Structure of the Cortex: 6. Describe the “look” of the vertebral cortex. ...
The Signal - WM Keck Center for Behavioral Biology
... Lomvardas began by highlighting that he uses genetic tools to study regulation of expression of olfactory receptors within mouse olfactory neurons. He explained that development is orchestrated by genetically hardwired signaling gradients, which in different tissues activate sets of transcription fa ...
... Lomvardas began by highlighting that he uses genetic tools to study regulation of expression of olfactory receptors within mouse olfactory neurons. He explained that development is orchestrated by genetically hardwired signaling gradients, which in different tissues activate sets of transcription fa ...
Neurons and Nervous System
... potential when they open and close. The membrane is depolarized when Na+ enters the cell and the inside of the neuron becomes less negative than when at rest. If gated K+ channels open and K+ leaves, the cell becomes more negative inside and the membrane is ...
... potential when they open and close. The membrane is depolarized when Na+ enters the cell and the inside of the neuron becomes less negative than when at rest. If gated K+ channels open and K+ leaves, the cell becomes more negative inside and the membrane is ...
Lecture-20-2013-Bi
... Some neurons selectively respond to urine from mice of the same sex, others to urine of the opposite sex. Unlike ORNs, their responses are narrowly tuned; no neurons were ever observed to respond to more than one compound. A behavioral assay: mice produce ultrasonic calls (‘whistling’) in response t ...
... Some neurons selectively respond to urine from mice of the same sex, others to urine of the opposite sex. Unlike ORNs, their responses are narrowly tuned; no neurons were ever observed to respond to more than one compound. A behavioral assay: mice produce ultrasonic calls (‘whistling’) in response t ...
Chapter 7 part two
... One theory that brings together all of the reviewed attention effects (top-down biases, gain modulation, enhancement and suppression) is Desimone and Duncan’s ‘biased competition’model of attention. The theory rests on three assumptions. First, given the limits on our ability to process several stim ...
... One theory that brings together all of the reviewed attention effects (top-down biases, gain modulation, enhancement and suppression) is Desimone and Duncan’s ‘biased competition’model of attention. The theory rests on three assumptions. First, given the limits on our ability to process several stim ...
An optical neural interface: in vivo control of rodent
... electrodes remain incapable of reliably targeting specific cell types (e.g. excitatory or inhibitory neurons) within neural tissue. This obstacle has major scientific and clinical implications. For example, there is intense debate among physicians, neuroengineers and neuroscientists regarding the re ...
... electrodes remain incapable of reliably targeting specific cell types (e.g. excitatory or inhibitory neurons) within neural tissue. This obstacle has major scientific and clinical implications. For example, there is intense debate among physicians, neuroengineers and neuroscientists regarding the re ...
An optical neural interface: in vivo control of
... electrodes remain incapable of reliably targeting specific cell types (e.g. excitatory or inhibitory neurons) within neural tissue. This obstacle has major scientific and clinical implications. For example, there is intense debate among physicians, neuroengineers and neuroscientists regarding the re ...
... electrodes remain incapable of reliably targeting specific cell types (e.g. excitatory or inhibitory neurons) within neural tissue. This obstacle has major scientific and clinical implications. For example, there is intense debate among physicians, neuroengineers and neuroscientists regarding the re ...
Hearing the Call of Neurons PowerPoint
... How do we follow the branches? Left: schematic drawing by Santiago Ramon y Cajal (circa 1900). Right: section through a rat retina. ...
... How do we follow the branches? Left: schematic drawing by Santiago Ramon y Cajal (circa 1900). Right: section through a rat retina. ...
Homeostasis Test%28CNS%29-Tawsif Hossain
... temperature of the skin surface. A nerve impulse would be sent through the sensory neurons to the interneurons and finally the motor neurons. It is critical that this information travels fast in order for the body to react appropriately. ...
... temperature of the skin surface. A nerve impulse would be sent through the sensory neurons to the interneurons and finally the motor neurons. It is critical that this information travels fast in order for the body to react appropriately. ...
The Nervous System
... (12 pairs of cranial nerves and 31 pairs of spinal nerves), which serve as linkage between the CNS and the body. 4. PNS can be subdivided into Sensory (afferent) nerves and Motor (efferent) nerves. Sensory nerves send nerve impulse from the body to CNS, while motor nerves send impulse from CNS to ef ...
... (12 pairs of cranial nerves and 31 pairs of spinal nerves), which serve as linkage between the CNS and the body. 4. PNS can be subdivided into Sensory (afferent) nerves and Motor (efferent) nerves. Sensory nerves send nerve impulse from the body to CNS, while motor nerves send impulse from CNS to ef ...
(Figure 4B) in 12 month old Cln5-/- mice. To survey effects on glial
... neurons, yet no loss of their target neurons in lamina IV of somatosensory cortex. Our preliminary data suggest that this vulnerability of thalamic neurons is an early event in pathogenesis. Cln5 deficient mice also exhibit pronounced glial responses within individual thalamic nuclei, which appear t ...
... neurons, yet no loss of their target neurons in lamina IV of somatosensory cortex. Our preliminary data suggest that this vulnerability of thalamic neurons is an early event in pathogenesis. Cln5 deficient mice also exhibit pronounced glial responses within individual thalamic nuclei, which appear t ...
Visual Brain
... Figure 4.17 (a) Red and blue areas show the extent of stimuli that were presented while a person was in an fMRI scanner. (b) Red and blue indicates areas of the brain activated by the stimulation in (a). (From Dougherty et al., 2003.) ...
... Figure 4.17 (a) Red and blue areas show the extent of stimuli that were presented while a person was in an fMRI scanner. (b) Red and blue indicates areas of the brain activated by the stimulation in (a). (From Dougherty et al., 2003.) ...
Modeling the brain
... Electrochemical in axons and dendrites; chemical in synapses Information processing – seems relatively clear Nonlinearly weighted sums of incoming data Information storage – still enigmatic Short term maybe clear, chemical changes in synapses ...
... Electrochemical in axons and dendrites; chemical in synapses Information processing – seems relatively clear Nonlinearly weighted sums of incoming data Information storage – still enigmatic Short term maybe clear, chemical changes in synapses ...
The Nanostructure of the Nervous System and the Impact
... In general, lipid soluble factors are able to cross the BBB much more readily than less lipid soluble factors, a fact that has been an important consideration for drug delivery into the CNS and is an important consideration for nanotechnological approaches that strive to do the same. Between the neu ...
... In general, lipid soluble factors are able to cross the BBB much more readily than less lipid soluble factors, a fact that has been an important consideration for drug delivery into the CNS and is an important consideration for nanotechnological approaches that strive to do the same. Between the neu ...
Nervous System Notes
... knob, causing release of calcium ions to diffuse into the knob Increased calcium concentrations trigger the release of neurotransmitters via exocytosis Neurotransmitters diffuse across the synaptic cleft and bind to receptor molecules causing ion channels to open This causes postsynaptic poten ...
... knob, causing release of calcium ions to diffuse into the knob Increased calcium concentrations trigger the release of neurotransmitters via exocytosis Neurotransmitters diffuse across the synaptic cleft and bind to receptor molecules causing ion channels to open This causes postsynaptic poten ...
Large-scale recording of neuronal ensembles
... the variant (brain-generated) features, including the temporal relations among neuronal assemblies and assembly members from the invariant features represented by the physical world might provide clues about the brain’s perspective on its environment. How should one proceed to test these competing f ...
... the variant (brain-generated) features, including the temporal relations among neuronal assemblies and assembly members from the invariant features represented by the physical world might provide clues about the brain’s perspective on its environment. How should one proceed to test these competing f ...
NERVOUS SYSTEM - Welcome to the Health Science Program
... the synapse to another neuron by a chemical called a neurotransmitter ...
... the synapse to another neuron by a chemical called a neurotransmitter ...
the summary and précis of the conference
... itself that gives rise to the peaks. This tells us that we really should think of ERPs as being not separate from, but rather a property of, the on-going background EEG, the continuous, spontaneous activity. The modulation of the EEG with state of arousal and attention suggest that it might reflect ...
... itself that gives rise to the peaks. This tells us that we really should think of ERPs as being not separate from, but rather a property of, the on-going background EEG, the continuous, spontaneous activity. The modulation of the EEG with state of arousal and attention suggest that it might reflect ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.