
Nerve activates contraction
... Continuation of the Nerve Impulse between Neurons Impulses are able to cross the synapse to another nerve Neurotransmitter is released from a nerve’s axon terminal The dendrite of the next neuron has receptors that are stimulated by the neurotransmitter An action potential is started in the ...
... Continuation of the Nerve Impulse between Neurons Impulses are able to cross the synapse to another nerve Neurotransmitter is released from a nerve’s axon terminal The dendrite of the next neuron has receptors that are stimulated by the neurotransmitter An action potential is started in the ...
Glial Cells: The Other Cells of the Nervous System
... The neurons and the glia In the brain and spinal cord are bathed in cerebrospinal fluid that maintains a regulated ionic milieu in the tissue. In most areas of the brain, blood components such as cells and large proteins are not allowed to freely permeate the brain tissue. This barrier is called the ...
... The neurons and the glia In the brain and spinal cord are bathed in cerebrospinal fluid that maintains a regulated ionic milieu in the tissue. In most areas of the brain, blood components such as cells and large proteins are not allowed to freely permeate the brain tissue. This barrier is called the ...
Marieb_ch7a
... Continuation of the Nerve Impulse between Neurons Impulses are able to cross the synapse to another nerve Neurotransmitter is released from a nerve’s axon terminal The dendrite of the next neuron has receptors that are stimulated by the neurotransmitter An action potential is started in the ...
... Continuation of the Nerve Impulse between Neurons Impulses are able to cross the synapse to another nerve Neurotransmitter is released from a nerve’s axon terminal The dendrite of the next neuron has receptors that are stimulated by the neurotransmitter An action potential is started in the ...
Distinct representations of olfactory information in different cortical
... spatial preference in any dimension. High-resolution multiphoton imaging reveals varicosities likely to be axonal boutons (Supplementary Fig. 4). The spatial distribution of these varicosities is similar in every field imaged and is independent of glomerular origin, indicating that mitral and tufted ...
... spatial preference in any dimension. High-resolution multiphoton imaging reveals varicosities likely to be axonal boutons (Supplementary Fig. 4). The spatial distribution of these varicosities is similar in every field imaged and is independent of glomerular origin, indicating that mitral and tufted ...
Visual Properties of Neurons in a Polysensory Area in Superior
... Most STP units, 70% of the 199 tested, had little or no preference for stimulus size, shape, orientation, or contrast. These nonselective units would respond similarly to spots and slits of light, to shadows, to slides and photographs of complex objects, and to three-dimensional objects. Many of the ...
... Most STP units, 70% of the 199 tested, had little or no preference for stimulus size, shape, orientation, or contrast. These nonselective units would respond similarly to spots and slits of light, to shadows, to slides and photographs of complex objects, and to three-dimensional objects. Many of the ...
Integrated model of visual processing
... achieve this combination is by exchanging information between neurons in higher order areas coding for different attributes. However, the level of complexity of the computation and the fine grain of the representation that is often needed are probably impossible to achieve with the rather sparse set ...
... achieve this combination is by exchanging information between neurons in higher order areas coding for different attributes. However, the level of complexity of the computation and the fine grain of the representation that is often needed are probably impossible to achieve with the rather sparse set ...
Assisted morphogenesis: glial control of dendrite
... documented [1]. This diversity is in no small part a result of each dendrite’s unique task: to gather information from specific synaptic partners or from the environment, and to transmit this information to the axon. In mammals, dendritic arbors can be highly branched, and individual dendrite branch ...
... documented [1]. This diversity is in no small part a result of each dendrite’s unique task: to gather information from specific synaptic partners or from the environment, and to transmit this information to the axon. In mammals, dendritic arbors can be highly branched, and individual dendrite branch ...
Component process model of memory
... – hypothalamus composed of small nuclei; involved in feeding, sexual behaviour, sleeping, temperature regulation, blood pressure, heart rate, etc. – Some of these functions are accomplished by hormones (chemicals that affect various organs) – Hippocampus located at the anterior end of the temporal l ...
... – hypothalamus composed of small nuclei; involved in feeding, sexual behaviour, sleeping, temperature regulation, blood pressure, heart rate, etc. – Some of these functions are accomplished by hormones (chemicals that affect various organs) – Hippocampus located at the anterior end of the temporal l ...
Supplementary Figure Legends - Word file (28 KB )
... Figure S1. Expression patterns of eight GAL4 drivers within the MB peduncle. (a) Expression of a nuclear-targeted GFP reporter was driven by each of eight MB GAL4 drivers. Confocal images of brain whole mounts were deconvoluted, and virtual crosssections were reconstructed through the MB peduncle pr ...
... Figure S1. Expression patterns of eight GAL4 drivers within the MB peduncle. (a) Expression of a nuclear-targeted GFP reporter was driven by each of eight MB GAL4 drivers. Confocal images of brain whole mounts were deconvoluted, and virtual crosssections were reconstructed through the MB peduncle pr ...
from discrete neuronal ensembles to serial order
... In summary, it appears that the cortex can serve the function of merging multimodal information. This multimodal merging of information is not done by direct links between primary areas, but necessitates intermediate neuronal steps. The intervening neurons between sensory and motor neurons in the co ...
... In summary, it appears that the cortex can serve the function of merging multimodal information. This multimodal merging of information is not done by direct links between primary areas, but necessitates intermediate neuronal steps. The intervening neurons between sensory and motor neurons in the co ...
consciousness as an afterthought
... to room in his home (spatial imagery test). Data from normal subjects showed that the motor test would activate the supplementary motor area whereas the spatial test would activate the parahippocampal gyrus. This clinically unresponsive patient was told to think of one scene to indicate a “yes” answ ...
... to room in his home (spatial imagery test). Data from normal subjects showed that the motor test would activate the supplementary motor area whereas the spatial test would activate the parahippocampal gyrus. This clinically unresponsive patient was told to think of one scene to indicate a “yes” answ ...
Spinal Cord
... Pain Perceptions – based on expectations, past experience, anxiety, suggestions Affective – one’s emotional factors that can affect pain experience Behavioral – how one expresses or controls pain Cognitive – one’s beliefs (attitudes) about pain ...
... Pain Perceptions – based on expectations, past experience, anxiety, suggestions Affective – one’s emotional factors that can affect pain experience Behavioral – how one expresses or controls pain Cognitive – one’s beliefs (attitudes) about pain ...
Locus coeruleus - Rice CAAM Department
... The genetic defect of the transcriptional regulator MECP2 is responsible for Rett syndrome[8] . A MeCP2 deficiency has been associated to catecholaminergic dysfunctions related to autonomic and sympathoadrenergic system in mouse models of RTT. The Locus Coeruleus is the major source of noradrenergic ...
... The genetic defect of the transcriptional regulator MECP2 is responsible for Rett syndrome[8] . A MeCP2 deficiency has been associated to catecholaminergic dysfunctions related to autonomic and sympathoadrenergic system in mouse models of RTT. The Locus Coeruleus is the major source of noradrenergic ...
Practice Quiz - Kingsborough Community College
... Multiple Choice: use your scantron and darken the space of the letter of the best answer to each question. 1. The autonomic nervous system (ANS) is the motor portion for a. somatic reflexes b. visceral reflexes c. all peripheral reflexes d. skeletal muscular reflexes 2. Autonomic nerve impulses can ...
... Multiple Choice: use your scantron and darken the space of the letter of the best answer to each question. 1. The autonomic nervous system (ANS) is the motor portion for a. somatic reflexes b. visceral reflexes c. all peripheral reflexes d. skeletal muscular reflexes 2. Autonomic nerve impulses can ...
Nerve Cells and Insect Behavior—Studies on Crickets1 This report
... (Statements made by T. H. Bullock, 1984.) produce them in a burrow which they modify to an exponential horn which amplifies sounds of the correct carrier frequency. er's acoustic signals must be decoded by Flying conspecifics hear such signals already the receiver. The nervous system of the at dista ...
... (Statements made by T. H. Bullock, 1984.) produce them in a burrow which they modify to an exponential horn which amplifies sounds of the correct carrier frequency. er's acoustic signals must be decoded by Flying conspecifics hear such signals already the receiver. The nervous system of the at dista ...
The LIM and POU homeobox genes ttx-3 and unc
... factor initiates and maintains the terminal differentiation program of dopaminergic neurons in the midbrain (Smidt and Burbach, 2009), whereas the Pet1 transcription factor initiates and maintains the terminal differentiation program of serotonergic neurons (Liu et al., 2010). However, few neuronal ...
... factor initiates and maintains the terminal differentiation program of dopaminergic neurons in the midbrain (Smidt and Burbach, 2009), whereas the Pet1 transcription factor initiates and maintains the terminal differentiation program of serotonergic neurons (Liu et al., 2010). However, few neuronal ...
Brain and Nervous System Overview
... ~300 vesicles per action potential containing chemical transmitter (excitatory or inhibitory) (i.e. ACH acetylcholine or GABA) Each vesicle contains ~10,000 ACH and are passed to postsynaptic site through exocytosis in < 100 microsec. Transmitter causes change in post-synaptic membrane permeability ...
... ~300 vesicles per action potential containing chemical transmitter (excitatory or inhibitory) (i.e. ACH acetylcholine or GABA) Each vesicle contains ~10,000 ACH and are passed to postsynaptic site through exocytosis in < 100 microsec. Transmitter causes change in post-synaptic membrane permeability ...
Life and Death of Neurons in the Aging Brain
... neurons as “missing,” because they represent only a few percent of the total number of neurons and likely still appear normal in the Nissl stains used to estimate total neuron number. Despite these similarities, there are qualitative and quantitative differences between normal aging and AD with resp ...
... neurons as “missing,” because they represent only a few percent of the total number of neurons and likely still appear normal in the Nissl stains used to estimate total neuron number. Despite these similarities, there are qualitative and quantitative differences between normal aging and AD with resp ...
SCENTS AND SENSIBILITY: A MOLECULAR LOGIC OF OLFACTORY PERCEPTION
... The completed sequence of both the murine and human genome ultimately identified 1300 odorant receptors in the mouse (12,13) and 500 in humans (14,15,16). If mice possess 20,000 genes, then as much as 5% of the genome, one in 20 genes encodes the odorant receptors. A large family of odorant receptor ...
... The completed sequence of both the murine and human genome ultimately identified 1300 odorant receptors in the mouse (12,13) and 500 in humans (14,15,16). If mice possess 20,000 genes, then as much as 5% of the genome, one in 20 genes encodes the odorant receptors. A large family of odorant receptor ...
Anatomy Review
... a. action potential b. synaptic potential 18. (Page 5.) Label the diagrams on page 5. 19. (Page 5.) In the brain, a variety of synapses have evolved to serve complex transmission needs between neurons. Synapses located between axon terminals of one neuron and ______, ______, or ______ of another are ...
... a. action potential b. synaptic potential 18. (Page 5.) Label the diagrams on page 5. 19. (Page 5.) In the brain, a variety of synapses have evolved to serve complex transmission needs between neurons. Synapses located between axon terminals of one neuron and ______, ______, or ______ of another are ...
1 - White Rose eTheses Online
... Lysosomal storage disorders (LSDs) are a group of approximately 45 diseases characterised by the accumulation of undegraded material in the lysosomes, due to the dysfunction of some component of lysosomal function. The main causes of lysosomal dysfunction are mutations affecting the lysosomal hydrol ...
... Lysosomal storage disorders (LSDs) are a group of approximately 45 diseases characterised by the accumulation of undegraded material in the lysosomes, due to the dysfunction of some component of lysosomal function. The main causes of lysosomal dysfunction are mutations affecting the lysosomal hydrol ...
The neural basis of the speed–accuracy tradeoff - Eric
... fast and stimulus onset. Under the assumption that the observed BOLD signal in these areas is produced by the activity of integrator neurons, the data from these three fMRI studies suggest that speed instructions increase the baseline activity of these neurons. We are not aware of any neurophysiolog ...
... fast and stimulus onset. Under the assumption that the observed BOLD signal in these areas is produced by the activity of integrator neurons, the data from these three fMRI studies suggest that speed instructions increase the baseline activity of these neurons. We are not aware of any neurophysiolog ...
full text pdf
... 1998b). They include fast and prolonged depolarization mediated by 5-HT3 and 5-HT1P receptors, respectively, and an indirect effect that involves the stimulation of cholinergic interneurons (supplying the SO neurons) via 5-HT3 receptor. Mawe and Kennedy (1998, 1999) have performed two experiments in ...
... 1998b). They include fast and prolonged depolarization mediated by 5-HT3 and 5-HT1P receptors, respectively, and an indirect effect that involves the stimulation of cholinergic interneurons (supplying the SO neurons) via 5-HT3 receptor. Mawe and Kennedy (1998, 1999) have performed two experiments in ...
Role of the trigeminal mesencephalic nucleus in rat whisker pad
... were previously identified by their responses to masseter muscle stretching. Changes in TMne spontaneous electrical activities, analyzed under baseline conditions and during whisking movements, were statistically evaluated using Student’s t-test for paired observations. Results: Neuroanatomical expe ...
... were previously identified by their responses to masseter muscle stretching. Changes in TMne spontaneous electrical activities, analyzed under baseline conditions and during whisking movements, were statistically evaluated using Student’s t-test for paired observations. Results: Neuroanatomical expe ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.