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Neurones & the Action Potential
Neurones & the Action Potential

... Even when a nerve cell is not conducting an impulse, for each ATP molecule that’s hydrolysed, it is actively transporting 3 molecules Na+ out of the cell and 2 molecules of K+ into the cell, at the same time by means of the sodium-potassium pump. ...
Neuroscience Course Conference
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Neurons, Synapses, the Nervous System

... impulse) is an all-or-none response to depolarization of the nerve cell. A stimulus opens voltage-gated sodium channels and Na+ ions enter the cell, bringing the membrane potential to a positive value. In order to generate an action potential, a certain level of depolarization must be achieved, know ...
Nervous System Ch 10 Notes - Reading Community Schools
Nervous System Ch 10 Notes - Reading Community Schools

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click - Uplift Education
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GLOSSOPHARYNGEAL NERVE

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Objectives: The student shall know the facts, understand the
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Lectures220Week7Note..

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... B. This idea that the membrane potential (Vm) at any time is governed by the equilibrium potentials of the individual ions along with their relative permeabilities is described quantitatively by the Goldman equation. Vm =58 log (Pk[K]out + PNa[Na]out + PCl[Cl]in)/ (Pk[K]in + PNa[Na]in + PCl[Cl]out) ...
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neurology1ned2013 31.5 KB - d
neurology1ned2013 31.5 KB - d

... communicate by using chemical signals that generate electricity. Electricity is the movement of charge, specifically e- (negative). Neurotransmitters control the movement of ions across a membrane. This allows nerves to move impulses. The SATII expects some detail about this. I will try to address a ...
CHAPTER 28 Nervous Systems
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irons.conroeisd.net

... nerve impulse passes from one nerve cell to another nerve cell, muscle cell, or a gland cell. ...
Assignment: Sensing mechanical changes in firing neurons
Assignment: Sensing mechanical changes in firing neurons

... membrane is only a few nanometers thick, causing an electrical field strength over the cell membrane in the order of 20∙106 Volts/meter. When an action potential travels down the axon, deviations from this resting potential in the order of 100 milliVolts occur, causing a strong change in electrical ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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