D2 receptor overexpression in the striatum leads to a deficit in
... striatal D2R-OE mice, we tested the effects of the D1/D5 agonist SKF-81297 on the evoked IPSC and EPSC trains in both transgenic and control mice. SKF-81297 is a highly D1-selective agonist, which has a Ki for the D1 receptor of ∼2 nM but has a Ki for the D2R of ∼1,000 nM (24). We and others recentl ...
... striatal D2R-OE mice, we tested the effects of the D1/D5 agonist SKF-81297 on the evoked IPSC and EPSC trains in both transgenic and control mice. SKF-81297 is a highly D1-selective agonist, which has a Ki for the D1 receptor of ∼2 nM but has a Ki for the D2R of ∼1,000 nM (24). We and others recentl ...
PDF version - UTRGV Faculty Web
... into anterior ventral (N1AV) and posterior ventral (N1PV) branches (Elson 1996, Faulkes & Paul 1997), although this branching point is quite distal from the ganglia (particularly in posterior ganglia), in contrast to Pacifastacus leniusculus, Blepharipoda occidentalis, and Munida quadrispina, where ...
... into anterior ventral (N1AV) and posterior ventral (N1PV) branches (Elson 1996, Faulkes & Paul 1997), although this branching point is quite distal from the ganglia (particularly in posterior ganglia), in contrast to Pacifastacus leniusculus, Blepharipoda occidentalis, and Munida quadrispina, where ...
the brain`s concepts: the role of the sensory
... Concepts, from this perspective, were conceived of as abstract, amodal, and arbitrary, represented in some “language of thought” (Fodor, 1975, 1987), made up of symbols and having the properties of productivity and compositionality, among others. In Fodor’s theory (see Fodor, 1975), the purported am ...
... Concepts, from this perspective, were conceived of as abstract, amodal, and arbitrary, represented in some “language of thought” (Fodor, 1975, 1987), made up of symbols and having the properties of productivity and compositionality, among others. In Fodor’s theory (see Fodor, 1975), the purported am ...
Review - Society for Developmental Biology
... In amphibians, the CMZ responds to retinal damage by upregulating its production of new neurons (Reh, 1987). Early studies of retinal regeneration in amphibians demonstrated that this zone makes a contribution to regenerated retina, though the RPE is the primary source (see below). Studies of cell-s ...
... In amphibians, the CMZ responds to retinal damage by upregulating its production of new neurons (Reh, 1987). Early studies of retinal regeneration in amphibians demonstrated that this zone makes a contribution to regenerated retina, though the RPE is the primary source (see below). Studies of cell-s ...
the brain`s concepts: the role of the sensory
... Concepts, from this perspective, were conceived of as abstract, amodal, and arbitrary, represented in some “language of thought” (Fodor, 1975, 1987), made up of symbols and having the properties of productivity and compositionality, among others. In Fodor’s theory (see Fodor, 1975), the purported am ...
... Concepts, from this perspective, were conceived of as abstract, amodal, and arbitrary, represented in some “language of thought” (Fodor, 1975, 1987), made up of symbols and having the properties of productivity and compositionality, among others. In Fodor’s theory (see Fodor, 1975), the purported am ...
PDF
... cell, the ipsilateral OPQ cell that gives rise to the 0, P, and Q ectoteloblasts. The positions within the ganglion of neuronal populations derived from each of these sources are relatively invariant from segment to segment and from specimen to specimen. Other nerve cord cells derive from the mesote ...
... cell, the ipsilateral OPQ cell that gives rise to the 0, P, and Q ectoteloblasts. The positions within the ganglion of neuronal populations derived from each of these sources are relatively invariant from segment to segment and from specimen to specimen. Other nerve cord cells derive from the mesote ...
1 CELLULAR AND NERVE FIBRE
... the observed sexual difference in the efficiency of the immune response establishes during T- cell development (Kovacs and Olsen 1998, Ansar-Ahmed et al. 1999). To elucidate mechanisms underlying sexual dimorphism in thymic NA level, we explored the density of noradrenergic nerve fibres and TH synth ...
... the observed sexual difference in the efficiency of the immune response establishes during T- cell development (Kovacs and Olsen 1998, Ansar-Ahmed et al. 1999). To elucidate mechanisms underlying sexual dimorphism in thymic NA level, we explored the density of noradrenergic nerve fibres and TH synth ...
Slides
... Slow variables represent activation variables of hyperpolarizing K+ currents. However, similar behavior could be achieved by defining slow variables in other ways, such as inactivation variables of depolarizing currents or as a combination of activation and deactivation Behaviors not restricted ...
... Slow variables represent activation variables of hyperpolarizing K+ currents. However, similar behavior could be achieved by defining slow variables in other ways, such as inactivation variables of depolarizing currents or as a combination of activation and deactivation Behaviors not restricted ...
Cortical Plasticity - Lund University Publications
... consequence of this is that the receptive field of a neuron enlarges for each relay site, and the cortical neurons have the largest receptive fields. A receptive field is the area on the skin innervated by a neuron (Gardner & Kandel, 2000; Gardner, Martin & Jessell, 2000), and for the neurons in the ...
... consequence of this is that the receptive field of a neuron enlarges for each relay site, and the cortical neurons have the largest receptive fields. A receptive field is the area on the skin innervated by a neuron (Gardner & Kandel, 2000; Gardner, Martin & Jessell, 2000), and for the neurons in the ...
Hypothalamic regulation of sleep and circadian rhythms
... were unable to fall back asleep. These patients had lesions involving the basal ganglia and adjacent anterior hypothalamus. Later experiments in animals identified a hypothalamic site involving the lateral preoptic area where lesions caused similar insomnia21,22. During the 1980s and 1990s, investig ...
... were unable to fall back asleep. These patients had lesions involving the basal ganglia and adjacent anterior hypothalamus. Later experiments in animals identified a hypothalamic site involving the lateral preoptic area where lesions caused similar insomnia21,22. During the 1980s and 1990s, investig ...
Chapter 11 Efferent Division: Autonomic and Somatic Motor Control
... Autonomic Reflexes and Homeostasis The behavioral responses are integrated in the brain centers responsible for : – Motivated behaviors – Control of movement Sensory information integrated into the cerebral cortex and the limbic system can create emotions which can furter influence autonomic output ...
... Autonomic Reflexes and Homeostasis The behavioral responses are integrated in the brain centers responsible for : – Motivated behaviors – Control of movement Sensory information integrated into the cerebral cortex and the limbic system can create emotions which can furter influence autonomic output ...
19. Senses General and Special
... that open to the outside of the body, such as the nasal cavity, oral cavity, vagina, and anal canal. Interoceptors (in t́ er-ō-sep t́ er; inter = between), also called visceroceptors, detect stimuli in internal organs (viscera). These receptors are primarily stretch receptors in the smooth muscle o ...
... that open to the outside of the body, such as the nasal cavity, oral cavity, vagina, and anal canal. Interoceptors (in t́ er-ō-sep t́ er; inter = between), also called visceroceptors, detect stimuli in internal organs (viscera). These receptors are primarily stretch receptors in the smooth muscle o ...
The neural basis of the speed–accuracy tradeoff - Eric
... ago. We review recent studies that show SAT is modulated in association and pre-motor areas rather than in sensory or primary motor areas. Furthermore, the studies suggest that emphasis on response speed increases the baseline firing rate of cortical integrator neurons. We also review current theori ...
... ago. We review recent studies that show SAT is modulated in association and pre-motor areas rather than in sensory or primary motor areas. Furthermore, the studies suggest that emphasis on response speed increases the baseline firing rate of cortical integrator neurons. We also review current theori ...
Mouse Nerve Growth Factor Prevents Degeneration of Axotomized
... nucleus of the DBB. The horizontal dashed line, which passes through the border of the middle with the lower third of the nucleus accumbens, demarcates the MSN from the nucleus of the DBB. b. In this mane. the MSN is readilv seoarated from the nucleus of the DBB (horizontal dashed Zine). c, In this ...
... nucleus of the DBB. The horizontal dashed line, which passes through the border of the middle with the lower third of the nucleus accumbens, demarcates the MSN from the nucleus of the DBB. b. In this mane. the MSN is readilv seoarated from the nucleus of the DBB (horizontal dashed Zine). c, In this ...
Nervous System Exams and Answers
... Which of the following is the correct path of light traveling into the eye? A. lens, cornea, retina, pupil, optic nerve B. cornea, optic nerve, pupil, retina, lens C. cornea, pupil, lens, retina, optic nerve ...
... Which of the following is the correct path of light traveling into the eye? A. lens, cornea, retina, pupil, optic nerve B. cornea, optic nerve, pupil, retina, lens C. cornea, pupil, lens, retina, optic nerve ...
Behavioral Objectives
... The retina has three layers of neurons. The rod and cones synapse with the bipolar cells, which in turn synapse with ganglion cells that initiate nerve impulses. As signals pass from layer to the next integration occurs because each layer contains fewer cells than the previous layer. Blind Spot Ther ...
... The retina has three layers of neurons. The rod and cones synapse with the bipolar cells, which in turn synapse with ganglion cells that initiate nerve impulses. As signals pass from layer to the next integration occurs because each layer contains fewer cells than the previous layer. Blind Spot Ther ...
Neurons - LPS.org
... process smells, tastes, and touch into nerve impulses. Without these receptor cells, your brain would be helpless. By itself, your brain cannot detect light, or sound, or smell. Just as you need your stereo to turn radio waves into something meaningful, your brain needs your senses and their recepto ...
... process smells, tastes, and touch into nerve impulses. Without these receptor cells, your brain would be helpless. By itself, your brain cannot detect light, or sound, or smell. Just as you need your stereo to turn radio waves into something meaningful, your brain needs your senses and their recepto ...
Action potential - Scranton Prep Biology
... – others inhibit a receiving cell’s activity by decreasing its ability to develop action potentials. ...
... – others inhibit a receiving cell’s activity by decreasing its ability to develop action potentials. ...
Cation-Chloride Cotransporters and Neuronal Function
... CCC functions are regulated by transcriptional control, alternative splicing, subcellular targeting, and posttranslational modifications that lead to cell-specific as well as discrete subcellular expression patterns of the distinct CCC proteins. (Upper left) An example of transcriptional control for ...
... CCC functions are regulated by transcriptional control, alternative splicing, subcellular targeting, and posttranslational modifications that lead to cell-specific as well as discrete subcellular expression patterns of the distinct CCC proteins. (Upper left) An example of transcriptional control for ...
Neural stem cells - Philosophical Transactions of the Royal Society B
... genetics have been well discussed in other reviews, here we will describe our proteomics-based studies. To search for NSC-supporting/activating factors, we used mesenchymal stromal cell (MSC) lines that have a limited capacity for neuronal differentiation (Kohyama et al. 2001). This choice was promp ...
... genetics have been well discussed in other reviews, here we will describe our proteomics-based studies. To search for NSC-supporting/activating factors, we used mesenchymal stromal cell (MSC) lines that have a limited capacity for neuronal differentiation (Kohyama et al. 2001). This choice was promp ...
The emerging framework of mammalian auditory hindbrain
... integration center (Middlebrooks and Arbor 2009). From there, information is passed to the medial geniculate body (MGN), a thalamic area in the forebrain, before reaching the auditory cortex. Most data concerning the anatomy of the auditory pathway have been obtained in mammalian model systems such ...
... integration center (Middlebrooks and Arbor 2009). From there, information is passed to the medial geniculate body (MGN), a thalamic area in the forebrain, before reaching the auditory cortex. Most data concerning the anatomy of the auditory pathway have been obtained in mammalian model systems such ...
Chapter 17 Intrinsic Optical Signal Imaging of Normal and Abnormal
... Recent experimental evidence has shown that an increase in CBV may be quite focal within the first 2 seconds after the onset of normal physiological neuronal activity (52, 67, 68, 81). The CBV response after epileptiform events, however, has only been investigated using autoradiography (1, 55, 75), ...
... Recent experimental evidence has shown that an increase in CBV may be quite focal within the first 2 seconds after the onset of normal physiological neuronal activity (52, 67, 68, 81). The CBV response after epileptiform events, however, has only been investigated using autoradiography (1, 55, 75), ...
Somatosensory System Organization and Texture Sensation in Rats
... 21.6C). Beyond the special case of whiskers, it is common to refer to a brain representation as a “map” whenever the spatial relationship among sensory receptors is conserved in the central representation of the sense organ. A historical note on the discovery of cortical somatosensory maps is given ...
... 21.6C). Beyond the special case of whiskers, it is common to refer to a brain representation as a “map” whenever the spatial relationship among sensory receptors is conserved in the central representation of the sense organ. A historical note on the discovery of cortical somatosensory maps is given ...