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LWW PPT Slide Template Master
LWW PPT Slide Template Master

... neurons • Neurotransmitters build chemical bridge between one neuron and another • With threshold stimulus, neuron generates impulse (action potential) – Depolarization – Refractory period – Repolarization Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins ...
Neuroethology of reward and decision making
Neuroethology of reward and decision making

... and motor preparation. In that study, monkeys were cued to shift gaze from a central light to one of two peripheral lights to receive a fruit juice reward. In separate blocks of trials, the authors varied the expected value of orienting to each light by varying either the size of reward or the proba ...
The LIM and POU homeobox genes ttx-3 and unc
The LIM and POU homeobox genes ttx-3 and unc

... Transcription factors that drive neuron type-specific terminal differentiation programs in the developing nervous system are often expressed in several distinct neuronal cell types, but to what extent they have similar or distinct activities in individual neuronal cell types is generally not well ex ...
Researchers inch closer to causes, cures for insomnia, narcolepsy
Researchers inch closer to causes, cures for insomnia, narcolepsy

... a protein that recognizes the HLA pattern on the outside of cells. Erroneous while somewhat effective, address only readings of the HLA pattern might cause the symptoms, not the underlying loss of an immune cell to mount an attack on neurons. In most cases, once the sympthe body’s own orexin-produci ...
Muscarine Hyperpolarizes a Subpopulation of Neurons by Activating
Muscarine Hyperpolarizes a Subpopulation of Neurons by Activating

... include a depolarization resulting from a reduction in a potassium conductance (Brown and Adams, 1980; Madison et al., 1987; Uchimura and North, 1990) and a hyperpolarization as a result of an increasein a potassiumconductance (Egan and North, 1986; McCormick and Prince, 1987; McCormick and Pape, 19 ...
A Beginner`s Guide to the Mathematics of Neural Networks
A Beginner`s Guide to the Mathematics of Neural Networks

... membrane potential and ring state). Right: close-up of a typical synapse. decrease. In the rst case the arriving signal will increase the probability of the receiving neuron to start ring itself, therefore such a synapse is called excitatory. In the second case the arriving signal will decrease t ...
Distinct Isoforms of the RFX Transcription Factor DAF
Distinct Isoforms of the RFX Transcription Factor DAF

... such as food, dauer pheromone, or nose touch (Perkins et al., 1986). Nevertheless, in the laboratory daf-19 mutants are viable and thus a suitable model to study ciliogenesis. We and others have identified a large number of direct DAF-19 target genes based on the presence of the x-box promoter seque ...
A Brainstem Network Mediating Apneic Reflexes in the Rat
A Brainstem Network Mediating Apneic Reflexes in the Rat

... then refilled with a solution of BDA (5–7%) and glutamate (0.5–1 mM) or, in three cases, a mixture of glutamate, BDA, and C TB. The pipette was then reintroduced into the brain at the predetermined dorsoventral coordinate where 6 –9 nl of the mixture was injected. The presence of glutamate in the tr ...
Information Processing in the Rostral Solitary Nucleus: Modulation
Information Processing in the Rostral Solitary Nucleus: Modulation

... 2010b) and ion channel expression patterns (Corson & Bradley, 2013; Suwabe & Bradley, 2009). Much more is known about the biophysical properties of rNST neurons and their cranial nerve inputs as a whole than is known about the differences between the ...
1 Part 1: The Brain - Sinoe Medical Association TM
1 Part 1: The Brain - Sinoe Medical Association TM

... which prevents wide changes in intracranial blood flow. When disorders of CSF flow occur, they may therefore  impact not only CSF movement, but also the intracranial blood flow, with subsequent neuronal and glial  vulnerabilities. The venous system is also important in this equation. Infants and pat ...
FISIOLOGI HIDUNG DAN SINUS PARANASAL
FISIOLOGI HIDUNG DAN SINUS PARANASAL

... must be changed by about 30% before a difference can be detected Comparable visual discrimination threshold is a 1% change in light intensity ...
FISIOLOGI HIDUNG DAN SINUS PARANASAL
FISIOLOGI HIDUNG DAN SINUS PARANASAL

... substance must be changed by about 30% before a difference can be detected Comparable visual discrimination threshold is a 1% change in light intensity ...
CORTICAL PLASTICITY: From Synapses to Maps
CORTICAL PLASTICITY: From Synapses to Maps

... is currently accepted that cortical maps are dynamic constructs that are remodeled in detail by behaviorally important experiences throughout life. A wide variety of neuronal response reconstruction (mapping) studies in different modalities conducted in a variety of mammalian species, including huma ...
MUSHROOM BODY MEMOIR: FROM MAPS TO MODELS
MUSHROOM BODY MEMOIR: FROM MAPS TO MODELS

... packed parallel fibres of the intrinsic mushroom body neurons, the Kenyon cells. These bundles are seen in all types of mushroom body, even those with small or no calyces that are found in some of the earliest insect species and in species with secondarily reduced olfactory systems1. The different c ...
Morphological Studies of Wobbler Mouse Dorsal Root Ganglia
Morphological Studies of Wobbler Mouse Dorsal Root Ganglia

... animal models have been suggested to cause these symptoms, such as oxidative stress due to mitochondrial dysfunction, protein aggregation, neuroinflammation in different parts of the central nervous system and impaired axonal transport [26]. Up till now, none of the cellular defects found have led t ...
Ultrastructure of the Outer Retina in the Killifish, Aphanius sirhani
Ultrastructure of the Outer Retina in the Killifish, Aphanius sirhani

... between the wandering phagocytes and the surrounding pigment cells could be detected (Fig. 1E). The retina is of the duplex type, i.e. it possesses rods and cones (Figs. 2A-B). Cones observed include the following types: single, unequal double (Figs. 2C) and triangular triple cones (Figs. 2D, 3A). T ...
Thalamic POm projections to the dorsolateral striatum of rats
Thalamic POm projections to the dorsolateral striatum of rats

... cytochrome oxidase to reveal thalamic cytoarchitecture (Land and Simons 1985; Wong-Riley 1979). The second series was processed for BDA as described before (Alloway et al. 1998; Kincaid and Wilson 1996). These sections were gently agitated in 0.3% H2O2 to reduce background enzymes and then in 0.1 M ...
What Causes Eye Pain? | SpringerLink
What Causes Eye Pain? | SpringerLink

... [41••]. TRPM8 activity is also influenced by discrete osmolality changes, so that small increases in osmolality augment by this mechanism cold thermoreceptor activity in the eye [54••, 55]. Finally, background potassium channels like the K2P channels, which stay open at basal tissue temperature act ...
PAX: A mixed hardware/software simulation platform for
PAX: A mixed hardware/software simulation platform for

... (action potentials) by computing the currents flowing through cell membrane and synaptic nodes. It is possible to reduce the size of these models to facilitate their computation. Other popular models are based on a phenomenological description of the neurons. They are well adapted to the study of co ...
An ultra small array of electrodes for stimulating multiple
An ultra small array of electrodes for stimulating multiple

... et al., 2003) to stimulate neural fibers. However, limitations on electrode densities have restricted the study of neighboring synapses on an individual neuron. The technique of focal photolysis of caged glutamate offers a high degree of control over the spatiotemporal characteristics of stimuli to ...
SCENTS AND SENSIBILITY: A MOLECULAR LOGIC OF OLFACTORY PERCEPTION
SCENTS AND SENSIBILITY: A MOLECULAR LOGIC OF OLFACTORY PERCEPTION

... (20,21). These experiments provide a solution to the first question; we recognize the vast array of molecular structures defined as odorants by maintaining in our genome a large number of genes encoding odorant receptors. The observation that over 1000 receptors are required to accommodate the detec ...
Information transmission and recovery in neural communications
Information transmission and recovery in neural communications

... among neurons may follow some of the patterns we discuss here, but we do not consider that here. In principle, neural signals are continuous in time and should be treated by continuous information theory 关17兴. However, we employ a discrete treatment since 共a兲 continuous treatment of complex signals ...
PDF File - Max-Planck
PDF File - Max-Planck

... least eight different sections. Sections were stained with 4⬘,6⬘-diamidino2-phenylindole (DAPI), and the different brain areas [ventricular zone (VZ)/subventricular zone (SVZ) and IZ, and deep and superficial cortical plate (CP) layers] were identified. Comparison between different treatments of the ...
Behavioral verification of associative learning in whisker
Behavioral verification of associative learning in whisker

... small pieces of metal wire to whiskers and placing the animal in an electromagnetic field, where free exploration was possible. Whisker stimulation (CS) was paired with a foot shock and freezing behavior was considered as a CR. One of the control groups of mice received the same stimuli but explicit ...
Reactions vs. Reflexes Lab
Reactions vs. Reflexes Lab

... Background: Have you ever had to react to a situation where something was flying at your face? If so, you probably used two of our body’s most important – as well as fastest – mechanisms for protecting your eyes: reflexes and reactions. You automatically closed your eyes as the object approached and ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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