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ipratropium (i-pra-troe-pee-um) - DavisPlus
ipratropium (i-pra-troe-pee-um) - DavisPlus

... replaced the discontinued Atrovent CFC (chlorofluorocarbon). Soy and CFC-allergic patients can now safely use the Atrovent HFA formulation. However, Combivent (ipratropium/albuterol combination) MDI does contain soya lecithin and is contraindicated in patients with a history of hypersensitivity to s ...
2nd Quarter Conference Call - Emisphere Technologies, Inc.
2nd Quarter Conference Call - Emisphere Technologies, Inc.

... Calcitonin to treat patients with knee osteoarthritis in patients aged 51-80 mainly in Europe; estimated completion in 2010  This study will be used to support the filing with health authorities worldwide  A second study, designed to meet FDA requirements for U.S. registration, was initiated in Oc ...
Pharmacodynamics
Pharmacodynamics

... Research is often limited with respect to duration and size. For this reason, in order to demonstrate efficacy, use is often made of surrogate outcome measures and not of clinical endpoints such as a decrease in mortality and morbidity • It is not possible to adequately distinguish rare adverse effe ...
Doxazosin Mylan tablet ENG SmPC
Doxazosin Mylan tablet ENG SmPC

... reduction is normally seen after 2 – 6 hours. Protein binding is high (98%). Distribution volume: 1 l/kg. Clearance: 1.3 ml/min/kg. Doxazosin is metabolised mainly in the liver and is primarily excreted in the faeces as metabolites (63 to 65%) or unchanged drug (5%). The effective half-life at stead ...
Pediatric Dosage Calculation
Pediatric Dosage Calculation

... to the hundredths place as this amount could be easily administered in a 1 mL syringe Example: If the answer was 0.75 mL, where would you draw the solution to in this syringe? ...
Spiriva® may slow decline in FEV , a measure of lung function in
Spiriva® may slow decline in FEV , a measure of lung function in

... delivery systems (such as MTS) to meet the needs of different patients. Shire aims to have a range of medicines in its ADHD portfolio, with Adderall XR® being the most prescribed treatment for ADHD in the ...
valproate-semisodium
valproate-semisodium

... of water, and not crushed or chewed. The daily dosage should be established according to age and body weight. The wide variation in individual sensitivity to Depakote should also be considered. There is no clear correlation between daily dose, plasma concentration and therapeutic effect. Optimum dos ...
very commonly seen in primary care often present with medical
very commonly seen in primary care often present with medical

... Information adapted from UpToDate website article: “Unipolar major depression in adults: Choosing initial treatment” by Paul Ciechanowski; section editor, Peter Roy-Byrne. Adaptation courtesy of Dr. Beth Chmelik, UW/Seattle VA. ...
FOI 067-1314 document 2 - Therapeutic Goods Administration (TGA)
FOI 067-1314 document 2 - Therapeutic Goods Administration (TGA)

... products of which are extensively excreted in the urine. Less than 1% of unchanged drug is recovered in the urine. No active metabolites have been detected in plasma. The clearance of gliclazide has been found to be slightly reduced as a function of age. This reduction, however, is not considered to ...
PRAMIPEXOLE for Parkinson`s Disease
PRAMIPEXOLE for Parkinson`s Disease

... retina (seen in albino rats given high doses, but not reported in humans). If patients have visual problems or history of retinal disease baseline testing is recommended by an ophthalmologist. At review by consultant patients will be asked about any night vision problems and checked for visual field ...
Rozerem - Takeda
Rozerem - Takeda

... Rare cases of angioedema involving the tongue, glottis or larynx have been reported in patients after taking the first or subsequent doses of ROZEREM. Some patients have had additional symptoms such as dyspnea, throat closing, or nausea and vomiting that suggest anaphylaxis. Some patients have requi ...
PDF of full prescribing information
PDF of full prescribing information

... Following oral (30 mg) administration of 14C-labelled terconazole, the half-life of elimination from the blood for the parent terconazole was 6.9 hours (range 4.0 - 11.3). Terconazole is extensively metabolized; both the Cmax and AUC for unchanged terconazole represented a very small fraction (2.1% ...
Generalised anxiety disorder
Generalised anxiety disorder

... generalised anxiety disorder (GAD) require long-term treatment, a trial of reduction and cessation of medication should be attempted after the patient has been symptom free for at least 6 months. The chance of return of symptoms is reduced if psychological interventions are used concurrently. Select ...
Joint COPD Guidelines
Joint COPD Guidelines

... Guided by side effects and clinical response (target plasma level 10–20 mg/L). Measure plasmatheophylline concentration 4–6 hours after dose by mouth and at least 5 days after starting oral treatment During an exacerbation the dose needs to be reduced by 50% if a macrolide or fluoroquinolone antibio ...
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS)

... • Oregacillin P73 had activity against the H. pylori bacteria in vivo after a 14-day course of therapy (in three out of four patients) • A longer duration of therapy with Oregacillin P73 appears to be indicated and may be required to exert a greater killing effect against the bacterial infection • A ...
Patients Perspective Towards Mail Order Services
Patients Perspective Towards Mail Order Services

... Insulin or Insulin Secretagogues: increases risk of hypoglycemia Take in the morning, with or without food ...
Second-line anti
Second-line anti

... well distributed into bile, aqueous humour, bronchial secretions, sputum and CSF.  Penetrates inflamed meninges only. ...
To help with relaxation, mental and physical balance, and maintain
To help with relaxation, mental and physical balance, and maintain

... Stable – Stability test ongoing according to ICH conditions zone 2 Non-irradiated Well tolerated in clinical trials and doses up to 5g per day are safe. ...
valproates - DavisPlus
valproates - DavisPlus

... Migraine Prophylaxis: Monitor frequency and intensity of migraine headaches. Geri: Assess geriatric patients for excessive somnolence. Assess for suicidal tendencies, especially during early therapy. Restrict amount of drug available to patient. Risk may be increased in children, adolescents, and ad ...
Imatinib
Imatinib

... drug efflux and decreased intracellular drug accumulation. Increased degradation and/or metabolism of the drug through as yet undefined mechanisms. ...
Catabasis Pharmaceuticals Announces Top
Catabasis Pharmaceuticals Announces Top

... 12 for the vastus lateralis (a large component of the quadriceps) were not statistically significant ...
HST-150/151 Mid
HST-150/151 Mid

... Releasing too slowly relative to clearance. 90% is absorbed, but the plasma concentration never gets above threshold. ...
Drug Dosage and Clinical Responses
Drug Dosage and Clinical Responses

... – Physiological – Two drugs produce opposite effects on the same system (epinephrine in the treatment of histamine-induced bronchospasm) ...
medication administration
medication administration

... administered without effect on another Precautions – actions to be taken prior to avoid risk/ensure a good result ...
PrVISANNE
PrVISANNE

... Adverse Drug Reaction Overview Undesirable effects are more common during the first months of treatment with VISANNE and subside with continued treatment. Clinical Trial Adverse Drug Reactions Because clinical trials are conducted under very specific conditions the adverse reaction rates observed in ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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