MARTINDALE - The Complete Drug Reference Danazol
... have been given and treatment is reviewed after 3 months. In the management of hereditary angioedema initial doses of 200 mg two or three times daily are given, and then reduced according to the patient's response. For pre-operative thinning of the endometrium danazol has been given in a dose of 40 ...
... have been given and treatment is reviewed after 3 months. In the management of hereditary angioedema initial doses of 200 mg two or three times daily are given, and then reduced according to the patient's response. For pre-operative thinning of the endometrium danazol has been given in a dose of 40 ...
The signal attenuation rat model of obsessive–compulsive disorder
... OCD and Tourette’s syndrome (Berridge et al. 2004). It is important to note that the above models were not created on the basis of a known mutation in humans that was found to be related to OCD. Rather, these models are based on behavioral similarity, i.e., the behavior of genetically modified mice ...
... OCD and Tourette’s syndrome (Berridge et al. 2004). It is important to note that the above models were not created on the basis of a known mutation in humans that was found to be related to OCD. Rather, these models are based on behavioral similarity, i.e., the behavior of genetically modified mice ...
Caffeine: Hero or Zero Caffeine is the most widely used, legal drug
... When caffeine is part of people’s everyday routine they can become dependent or addicted. Of course more and more will have to be consumed to produce the same effects within the body due to the ...
... When caffeine is part of people’s everyday routine they can become dependent or addicted. Of course more and more will have to be consumed to produce the same effects within the body due to the ...
pegylated interferon-alfa-2b
... Interferon alfa-2a, interferon alfa-2b and interferon beta-1b may increase blood levels of zidovudine (AZT, Retrovir). While this reaction may improve zidovudine's effectiveness, it also may increase the risk of blood and liver toxicity. Therefore, the dose of zidovudine may need to be reduced by as ...
... Interferon alfa-2a, interferon alfa-2b and interferon beta-1b may increase blood levels of zidovudine (AZT, Retrovir). While this reaction may improve zidovudine's effectiveness, it also may increase the risk of blood and liver toxicity. Therefore, the dose of zidovudine may need to be reduced by as ...
WEST VIRGINIA LEGISLATURE Senate Bill 454
... (A) Restrict the subdivision or development of a tract for any more intense or higher density occupancy than a single-family dwelling unit; (B) Propose or enforce rules applicable to single-family dwelling units for single-family dwelling unit sanitary sewerage disposal systems; or (C) Restrict any ...
... (A) Restrict the subdivision or development of a tract for any more intense or higher density occupancy than a single-family dwelling unit; (B) Propose or enforce rules applicable to single-family dwelling units for single-family dwelling unit sanitary sewerage disposal systems; or (C) Restrict any ...
Dopamine, Locus of Control, and the Exploration
... underconstrained decision. Recent computational studies of this exploration-exploitation tradeoff have found that variability in exploration across individuals is influenced by a functional polymorphism (Val158Met) in the catechol-O-methyltransferase (COMT) gene, whose protein product degrades synap ...
... underconstrained decision. Recent computational studies of this exploration-exploitation tradeoff have found that variability in exploration across individuals is influenced by a functional polymorphism (Val158Met) in the catechol-O-methyltransferase (COMT) gene, whose protein product degrades synap ...
Inderal (propranolol hydrochloride) Tablets Rx only
... (noncardiac) receptors may be involved. A central effect is also possible. Clinical studies have demonstrated that Inderal is of benefit in exaggerated physiological and essential (familial) tremor. PHARMACOKINETICS AND DRUG METABOLISM ...
... (noncardiac) receptors may be involved. A central effect is also possible. Clinical studies have demonstrated that Inderal is of benefit in exaggerated physiological and essential (familial) tremor. PHARMACOKINETICS AND DRUG METABOLISM ...
Depakene/Depakote/ Depakote
... increasingly become the medications of choice for the treatment of bipolar disorder, particularly in acute mania. In addition to its indication for epilepsy, Depakote has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of mania associated with bipolar disorder. The use ...
... increasingly become the medications of choice for the treatment of bipolar disorder, particularly in acute mania. In addition to its indication for epilepsy, Depakote has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of mania associated with bipolar disorder. The use ...
Table of Contents
... with a maximum tumor diameter of 2.0 cm, located on the trunk (excluding anogenital skin), neck, or extremities (excluding hands and feet), only when surgical methods are medically less appropriate and patient follow-up can be reasonably assured. o The histological diagnosis of superficial basal cel ...
... with a maximum tumor diameter of 2.0 cm, located on the trunk (excluding anogenital skin), neck, or extremities (excluding hands and feet), only when surgical methods are medically less appropriate and patient follow-up can be reasonably assured. o The histological diagnosis of superficial basal cel ...
Characterization of a novel model of chronic migraine
... Chronic migraine is a disabling condition that affects hundreds of millions of individuals worldwide. The development of novel migraine treatments has been slow, in part as a result of a lack of predicative animal models. We have developed a new model of chronic migraine involving the use of nitrogl ...
... Chronic migraine is a disabling condition that affects hundreds of millions of individuals worldwide. The development of novel migraine treatments has been slow, in part as a result of a lack of predicative animal models. We have developed a new model of chronic migraine involving the use of nitrogl ...
Chondroitin Sulphate: Antioxidant Properties and Beneficial Effects
... in vivo experimental models [17-21]. This antioxidant activity is probably due to their capacity to chelate transition metals like Cu++ or Fe++ that are in turn responsible for the initiation of Haber-Weiss and Fenton’s reaction [18, 21-22]. Chondroitin sulphate (CS) is the main GAG representative i ...
... in vivo experimental models [17-21]. This antioxidant activity is probably due to their capacity to chelate transition metals like Cu++ or Fe++ that are in turn responsible for the initiation of Haber-Weiss and Fenton’s reaction [18, 21-22]. Chondroitin sulphate (CS) is the main GAG representative i ...
Plasma Pharmacokinetics of Adriamycin and
... Table 2 shows the total body clearance and steady-state consists of a very rapid decline in plasma Adriamycin concentra tions. Initial concentrations are 50-fold higher than those ob volume of distribution of Adriamycin and the AUC of adriamycinol and Adriamycin for the 2 groups. Similar values were ...
... Table 2 shows the total body clearance and steady-state consists of a very rapid decline in plasma Adriamycin concentra tions. Initial concentrations are 50-fold higher than those ob volume of distribution of Adriamycin and the AUC of adriamycinol and Adriamycin for the 2 groups. Similar values were ...
Senior Scientist Computational Biology - Pharma
... The Organisation Committed to Improving the Lives of Patients Worldwide Celgene Corporation, a uniquely positioned entrepreneurial biopharmaceutical company, and its employees are working relentlessly to provide novel solutions for unmet medical needs in cancer and debilitating inflammatory diseases ...
... The Organisation Committed to Improving the Lives of Patients Worldwide Celgene Corporation, a uniquely positioned entrepreneurial biopharmaceutical company, and its employees are working relentlessly to provide novel solutions for unmet medical needs in cancer and debilitating inflammatory diseases ...
Methadone and Buprenorphine: Clinical Practice Guideline for
... and duties of the medical profession. Physicians may exercise reasonable discretion in their decision to act on the guidance provided, but should support a decision to follow a different action with a comprehensively documented rationale. For the purposes of this document, the term buprenorphine is ...
... and duties of the medical profession. Physicians may exercise reasonable discretion in their decision to act on the guidance provided, but should support a decision to follow a different action with a comprehensively documented rationale. For the purposes of this document, the term buprenorphine is ...
Should we be concerned about herbal remedies
... particularly India, for patients to seek concurrent treatment through more than one Indian Medicinal System as well as allopathy, or in Chinese herbalism to fraudulently incorporate pharmaceuticals in some remedies. This only compounds issues related to recognizing the source of potential side effec ...
... particularly India, for patients to seek concurrent treatment through more than one Indian Medicinal System as well as allopathy, or in Chinese herbalism to fraudulently incorporate pharmaceuticals in some remedies. This only compounds issues related to recognizing the source of potential side effec ...
Studies and Comparisons with Placebo
... is more effective in this regard than propranolol at comparable ß-blocking doses. Carvedilol also protects against neuronal damage in in vitro and in vivo models of brain ischaemia and has antiproliferative effects in vascular smooth muscle in vitro. Single oral doses of carvedilol as low as 12.5mg ...
... is more effective in this regard than propranolol at comparable ß-blocking doses. Carvedilol also protects against neuronal damage in in vitro and in vivo models of brain ischaemia and has antiproliferative effects in vascular smooth muscle in vitro. Single oral doses of carvedilol as low as 12.5mg ...
Dabigatran etexilate for the prevention of stroke in patients with
... cells, promotes chemotaxis of neutrophils to the site of injury and amplifies its own generation [12] . Thrombin activity is tightly regulated by endogenous anticoagulant feedback loops. The main pathway is initiated when thrombin binds to membrane-bound thrombomodulin. This complex catalyzes the co ...
... cells, promotes chemotaxis of neutrophils to the site of injury and amplifies its own generation [12] . Thrombin activity is tightly regulated by endogenous anticoagulant feedback loops. The main pathway is initiated when thrombin binds to membrane-bound thrombomodulin. This complex catalyzes the co ...
Actavis v ICOS
... the minimal effective dose for tadalafil and because a 5mg dose would be obvious in any event. Lilly does not agree. It contends that a dose of tadalafil as low as 5mg and the advantages it provides in terms of efficacy and low side effects were not obvious. Even if the skilled team embarked on a cl ...
... the minimal effective dose for tadalafil and because a 5mg dose would be obvious in any event. Lilly does not agree. It contends that a dose of tadalafil as low as 5mg and the advantages it provides in terms of efficacy and low side effects were not obvious. Even if the skilled team embarked on a cl ...
Impact of levalbuterol versus Albuterol in Kentucky Medicaid Patients
... treatment of asthma. Racemic albuterol has been used for more than 40 years but is associated with several side effects including tremor. When levalbuterol was approved in 2005 its manufacturer and several studies suggested that using levalbuterol results in better respiratory parameters, fewer hosp ...
... treatment of asthma. Racemic albuterol has been used for more than 40 years but is associated with several side effects including tremor. When levalbuterol was approved in 2005 its manufacturer and several studies suggested that using levalbuterol results in better respiratory parameters, fewer hosp ...
Acute administration of typical and atypical antipsychotics reduces
... A single non-anaesthetic dose of ketamine, a non-competitive NMDA receptor (NMDAR) antagonist with hallucinogenic properties, induces cognitive impairment and psychosis, and aggravates schizophrenia symptoms in patients. In conscious rats an equivalent dose of ketamine induces key features of animal ...
... A single non-anaesthetic dose of ketamine, a non-competitive NMDA receptor (NMDAR) antagonist with hallucinogenic properties, induces cognitive impairment and psychosis, and aggravates schizophrenia symptoms in patients. In conscious rats an equivalent dose of ketamine induces key features of animal ...
Greenway FL, Whitehouse MJ, Guttadauria M
... include a broad range of doses spanning 1.5–2 units on a log scale. The purpose of dose–response studies was twofold. First, dose–response studies demonstrated that acute BUP or NAL administration consistently and dose-dependently reduces food intake in fasted mice. Second, dose–response curves prov ...
... include a broad range of doses spanning 1.5–2 units on a log scale. The purpose of dose–response studies was twofold. First, dose–response studies demonstrated that acute BUP or NAL administration consistently and dose-dependently reduces food intake in fasted mice. Second, dose–response curves prov ...
Humulin 70/30
... diabetes, in patients with diabetic nerve disease, in patients using medications that block the sympathetic nervous system (e.g., beta-blockers) [see Drug Interactions (7)], or in patients who experience recurrent hypoglycemia. Risk Factors for Hypoglycemia ...
... diabetes, in patients with diabetic nerve disease, in patients using medications that block the sympathetic nervous system (e.g., beta-blockers) [see Drug Interactions (7)], or in patients who experience recurrent hypoglycemia. Risk Factors for Hypoglycemia ...
EXTEMPORANEOUS PREPARATION OF PAEDIATRIC ORAL
... The use of extemporaneous preparations can be considered as unlicensed drug use and these raise concerns about quality, stability, bioavailability, efficacy and safety. Currently, there are no appropriate and comprehensive published standards, and thus decisions in different steps of preparation pro ...
... The use of extemporaneous preparations can be considered as unlicensed drug use and these raise concerns about quality, stability, bioavailability, efficacy and safety. Currently, there are no appropriate and comprehensive published standards, and thus decisions in different steps of preparation pro ...
05 AIDS FOR CESSATION & CASE SCENARIO
... and cause stinging or redness Do not leave patch on skin for more than 24 hours— doing so may lead to skin irritation Adhesive remaining on skin may be removed with rubbing alcohol or acetone Dispose of used patch by folding it onto itself, completely ...
... and cause stinging or redness Do not leave patch on skin for more than 24 hours— doing so may lead to skin irritation Adhesive remaining on skin may be removed with rubbing alcohol or acetone Dispose of used patch by folding it onto itself, completely ...
Therapeutic approaches in arterial thrombosis
... pathways in platelets. Activation of the receptor function of GP IIb-IIIa is optimal when engagement of G12/13 or Gq signaling pathways is combined with Gi stimulation [26,27]. This combination occurs when either TXA2 (TP) receptor (G12/13, Gq), protease-activated receptor-1 (PAR-1) (G12/13, Gq), an ...
... pathways in platelets. Activation of the receptor function of GP IIb-IIIa is optimal when engagement of G12/13 or Gq signaling pathways is combined with Gi stimulation [26,27]. This combination occurs when either TXA2 (TP) receptor (G12/13, Gq), protease-activated receptor-1 (PAR-1) (G12/13, Gq), an ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.