recent advances in animal models of drug addiction
... will decrease self-administration of some unit doses but simultaneously increase self-administration of other doses. The interpretation of downward shifts in the dose–effect function also is sometimes problematic. Therefore, construction of full dose–effect functions is essential in selfadministrati ...
... will decrease self-administration of some unit doses but simultaneously increase self-administration of other doses. The interpretation of downward shifts in the dose–effect function also is sometimes problematic. Therefore, construction of full dose–effect functions is essential in selfadministrati ...
THERMOSENSITIVE HYDROGEL FOR CONTROLLED DRUG DELIVERY OF ANTICANCER AGENTS Research Article
... periods, re-growth of the vascular endothelial cells that support the tumor resumes, resulting in more aggressive cancers that are resistant to the cytotoxic drug. Continuous drug infusions have confirmed that constant low blood levels of an anticancer agent can be more effective than intense high d ...
... periods, re-growth of the vascular endothelial cells that support the tumor resumes, resulting in more aggressive cancers that are resistant to the cytotoxic drug. Continuous drug infusions have confirmed that constant low blood levels of an anticancer agent can be more effective than intense high d ...
direct-to-consumer advertising
... until the early 1980’s. However, recently it has radically changed the way prescription drugs are marketed (Holtz, 1998). As mentioned, DTC prescription drug ads are any promotional effort by a pharmaceutical company to offer prescription drug information to the general public through consumer-orien ...
... until the early 1980’s. However, recently it has radically changed the way prescription drugs are marketed (Holtz, 1998). As mentioned, DTC prescription drug ads are any promotional effort by a pharmaceutical company to offer prescription drug information to the general public through consumer-orien ...
Read "FDA Violation of the Rule of Law"
... Roosevelt administration, feeling its oats after the "switch in time that saved nine," called for adoption of the Food, Drug and C osmetic Act of 1938. That law required companies to submit New Drug Applications (NDA's) before introducing new pharmaceuticals into interstate commerce. In concessions ...
... Roosevelt administration, feeling its oats after the "switch in time that saved nine," called for adoption of the Food, Drug and C osmetic Act of 1938. That law required companies to submit New Drug Applications (NDA's) before introducing new pharmaceuticals into interstate commerce. In concessions ...
Drug Interactions
... he will not discuss any off-label indications for drugs used for the treatment of HIV infection. He will discuss drug-drug interaction information that has been presented at scientific meetings or published, which is not included in the FDA approved package insert. ...
... he will not discuss any off-label indications for drugs used for the treatment of HIV infection. He will discuss drug-drug interaction information that has been presented at scientific meetings or published, which is not included in the FDA approved package insert. ...
FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF Research Article
... Oral route is the most preferred route for administration of drugs. Tablets are the most popular oral formulation available in the market and widely preferred by the patients and physician alike. In long-term therapy for the treatment of chronic disease conditions, conventional formulations are admi ...
... Oral route is the most preferred route for administration of drugs. Tablets are the most popular oral formulation available in the market and widely preferred by the patients and physician alike. In long-term therapy for the treatment of chronic disease conditions, conventional formulations are admi ...
FORMULATION, EVALUATION AND OPTIMIZATION OF SOLID DISPERSION OF GLIPIZIDE
... stimulating the release of insulin from the pancreas and is typically prescribed to treat non insulin dependent diabetes mellitus12. The drug is insoluble in water, and its dissolution is considered to be a rate-determining step (i.e., an effective factor) in its absorption from the gastrointestinal ...
... stimulating the release of insulin from the pancreas and is typically prescribed to treat non insulin dependent diabetes mellitus12. The drug is insoluble in water, and its dissolution is considered to be a rate-determining step (i.e., an effective factor) in its absorption from the gastrointestinal ...
PHARMACEUTICALS: RESTRICTIONS IN USE AND AVAILABILITY
... clearly do not meet the criteria have been omitted after consultation with governments. Information received from non-governmental organizations has, in each case, been verified with governments. The information provided also includes references to relevant legal or statutory documents that enable t ...
... clearly do not meet the criteria have been omitted after consultation with governments. Information received from non-governmental organizations has, in each case, been verified with governments. The information provided also includes references to relevant legal or statutory documents that enable t ...
navigating the fda
... comparison if applicable, suggestion on how to be classified, indications for use, protocol outline with study endpoints, suggest N size. If drug results of animal study safety, pilot/lab, feasibility results, statistical methods to be used • List of questions for FDA ...
... comparison if applicable, suggestion on how to be classified, indications for use, protocol outline with study endpoints, suggest N size. If drug results of animal study safety, pilot/lab, feasibility results, statistical methods to be used • List of questions for FDA ...
Ophthalmic Preparations - triphasepharmasolutions.com
... USP general chapter Ophthalmic Ointments 771 (1) addresses some parameters and characteristics such as added substances, containers, metal particles and leakage for only ophthalmic ointments. In an effort to modernize this general chapter and align it to the other USP general chapters related to pha ...
... USP general chapter Ophthalmic Ointments 771 (1) addresses some parameters and characteristics such as added substances, containers, metal particles and leakage for only ophthalmic ointments. In an effort to modernize this general chapter and align it to the other USP general chapters related to pha ...
Therapeutic Drug Monitoring (TDM)
... TDM is the time the sample is taken in relation to the last dose of a drug, or the vein from which the sample is taken in relation to an infusion or injection site. As regards an infusion, the sample must be taken from a site in the body remote from the infusion site, whilst for an orally administer ...
... TDM is the time the sample is taken in relation to the last dose of a drug, or the vein from which the sample is taken in relation to an infusion or injection site. As regards an infusion, the sample must be taken from a site in the body remote from the infusion site, whilst for an orally administer ...
IN VIVO COMPARATIVE BIOAVAILABILITY STUDY OF TWO VALPROIC ACID SYRUP
... BA of different brands of an antiepileptic were reported [5-12]. For a successful long term therapy, is required an appropriate antiepileptic regimen and optimal dosing [13]. Prescribing a generic instead of innovator antiepileptic drugs may lead to either loss of seizure control or intoxication [14 ...
... BA of different brands of an antiepileptic were reported [5-12]. For a successful long term therapy, is required an appropriate antiepileptic regimen and optimal dosing [13]. Prescribing a generic instead of innovator antiepileptic drugs may lead to either loss of seizure control or intoxication [14 ...
Formulation and evaluation of Pseudoephedrine hydrochloride and
... to be useful as an anti-allergy agent for the treatment of seasonal allergic rhinitis symptoms such as sneezing and itching. Therefore an oral dosage composition containing both loratadine and pseudoephedrine is used for treating patients showing the sign and symptoms associated with upper respirato ...
... to be useful as an anti-allergy agent for the treatment of seasonal allergic rhinitis symptoms such as sneezing and itching. Therefore an oral dosage composition containing both loratadine and pseudoephedrine is used for treating patients showing the sign and symptoms associated with upper respirato ...
Margolin
... Preface: Quotations to Consider Before and While Reading the Paper: “To think that a man should be allowed a gun and not a drug!”3 “It will be instructive to consider some of the similarities between the medieval wars against witchcraft and the modern wars against drugcraft. In each of these contes ...
... Preface: Quotations to Consider Before and While Reading the Paper: “To think that a man should be allowed a gun and not a drug!”3 “It will be instructive to consider some of the similarities between the medieval wars against witchcraft and the modern wars against drugcraft. In each of these contes ...
DrugFacts MDMA 2013
... psychotherapy—although without the support of clinical trial research or FDA approval. In 1985, the Drug Enforce-‐ ment Administration labeled MDMA a Schedule I substance, or a drug with high abuse potential ...
... psychotherapy—although without the support of clinical trial research or FDA approval. In 1985, the Drug Enforce-‐ ment Administration labeled MDMA a Schedule I substance, or a drug with high abuse potential ...
Uppers, Downers, All Arounders, 7th Edition
... Prevention and Control Act of 1970, penalties for drug possession and sales have increased. To curtail drug availability, more severe penalties (longer prison terms, asset forfeiture, heavy fines) were levied against offenders. As a result, the prison population (federal, state, and local) has more ...
... Prevention and Control Act of 1970, penalties for drug possession and sales have increased. To curtail drug availability, more severe penalties (longer prison terms, asset forfeiture, heavy fines) were levied against offenders. As a result, the prison population (federal, state, and local) has more ...
colorimetric determination and validation of amlodipine
... formulation was found to be 5 mg. All the above studies do not suffer from any interference due to common excipients. Therefore it was shown that the proposed method could be successfully applied to estimate commercial pharmaceutical products containing Amlodipine besylate. Thus the above studies an ...
... formulation was found to be 5 mg. All the above studies do not suffer from any interference due to common excipients. Therefore it was shown that the proposed method could be successfully applied to estimate commercial pharmaceutical products containing Amlodipine besylate. Thus the above studies an ...
CHALLENGES AND KEY CONSIDERATIONS FOR THE
... Medical device manufacturers do not have the same challenges as their pharmaceutical counterparts, as devices are normally manufactured using plastics, metals or other materials that are easily adapted to terminal sterilisation. Sterility assurance is obviously still critical for this market and sta ...
... Medical device manufacturers do not have the same challenges as their pharmaceutical counterparts, as devices are normally manufactured using plastics, metals or other materials that are easily adapted to terminal sterilisation. Sterility assurance is obviously still critical for this market and sta ...
Application of Hot Stage Microscopy (HSM)
... A solid dispersion was defined as a dispersion of one or more active ingredients in a carrier or matrix at solid state prepared by the melting, solvent or melting-solvent method [1]. The fusion process is technically the less difficult method of preparing solid dispersions provided the drug and carr ...
... A solid dispersion was defined as a dispersion of one or more active ingredients in a carrier or matrix at solid state prepared by the melting, solvent or melting-solvent method [1]. The fusion process is technically the less difficult method of preparing solid dispersions provided the drug and carr ...
Public Health Law Webinar Series
... could make such products available using several mechanisms. The type of mechanism that might be used to allow for the emergency use of medical products during CBRN emergencies would depend on the specific scope and circumstances of an emergency and the products that might be needed (and how such pr ...
... could make such products available using several mechanisms. The type of mechanism that might be used to allow for the emergency use of medical products during CBRN emergencies would depend on the specific scope and circumstances of an emergency and the products that might be needed (and how such pr ...
63rd FIP Congress Sydney, Australia
... The Role of the Pharmacist in Encouraging Adherence to Long Term Treatments There are many reasons for seeking to improve adherence to long-term therapies for chronic diseases. The benefits include better health outcomes and improved quality of life and improved safety for the patient, as well as co ...
... The Role of the Pharmacist in Encouraging Adherence to Long Term Treatments There are many reasons for seeking to improve adherence to long-term therapies for chronic diseases. The benefits include better health outcomes and improved quality of life and improved safety for the patient, as well as co ...
GHB/Fantasy
... implied that GHB also comes in a bright blue liquid form (‘blue nitro’); however, it is important to note that manufacturers can change the colour of GHB by adding a different colour food dye. Generally, two broad groups of people have been known to take GHB. In the 1980s, bodybuilders used it to pr ...
... implied that GHB also comes in a bright blue liquid form (‘blue nitro’); however, it is important to note that manufacturers can change the colour of GHB by adding a different colour food dye. Generally, two broad groups of people have been known to take GHB. In the 1980s, bodybuilders used it to pr ...