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... We learned about DNA and the basis of its structure when we talked about biological macromolecules, what do you remember? What are the monomers called? What are the parts of the monomer? How do they connect to make a polymer? What are they two types of polymers? The GATC code provides instructions f ...
INTRODUCTION
INTRODUCTION

... The opposite strand is called the coding strand or the sense strand as well as the nontemplate strand  The base sequence is identical to the RNA transcript  Except for the substitution of uracil in RNA for thymine in DNA ...
group_presentation
group_presentation

... TIFFmRNA (Uncompressed) decompressor are needed to see this picture. recognizes both code Xs as intruders and destroys the doublestranded RNA along with the code X portion of the cell’s original mRNA • Step 4: because the Dice enzyme destroyed the code X in the cell’s mRNA code X will no longer be t ...
10/23 Gene expression in Prokaryotes
10/23 Gene expression in Prokaryotes

... Negative and Positive Control; Inducible and Repressible Operons • Negative repressible operons: The control at the operator site is negative. But such transcription is usually on and needs to be turned off, so the transcription is repressible. • Corepressor: a small molecule that binds to the re ...
Central Dogma of Genetics
Central Dogma of Genetics

... – Similar to DNA polymerase editing, newly inserted nucleotide is removed by reversing synthesis reaction. – Enzyme moves back one or more nucleotides, cleaves RNA, then resumes synthesis in forward direction. ...
Retroviruses ---The name retrovirus comes from the enzyme
Retroviruses ---The name retrovirus comes from the enzyme

... ---When there is enough rex, it regulates splicing of viral mRNAs. ---It binds RRE, a secondary RNA structure in the env RNA ---Rex directs nuclear export of mRNAs before they are fully spliced. These mRNAs encode ...
Introduction to Molecular Cell Biology (not tought by SK in 2010)
Introduction to Molecular Cell Biology (not tought by SK in 2010)

... Mitochondria have their own DNA, which replicates independent of the nuclear DNA 2. Genetic code of the mitochondria is different from the main code of the cell 3. Mitochondria have their own ribosomes on which some of the mitochondrial proteins are produced. Others are imported from the outside 4. ...
Protein Synthesis and Words - Hewlett
Protein Synthesis and Words - Hewlett

... an organism. We commonly call this our “traits”. Protein molecules are large and complex, composed of hundreds of amino acid units. In each kind of protein, the amino acid units are linked together in a definite and specific sequence. The sequence of amino acids in a protein molecule is determined b ...
Document
Document

... which is like a “glove” that the substrate fits into. ...
The Molecular Biology of Gene Function
The Molecular Biology of Gene Function

... to lack of regulatory controls (eg Lr34) OR less pleiotropy due to lack of pathway/function in new species (eg in native species affects 10 pathways but in new species only one is present). In general a gene that has multiple effects also has multiple controls – more closely related more likely to h ...
Document
Document

... • Cooperativity due to initial unstacking, which exposes bases to water, which destabilizes Hbonds, which leads to further denaturation ...
AP Biology Ch. 12 Reading Guide – Molecular Biology of the Gene
AP Biology Ch. 12 Reading Guide – Molecular Biology of the Gene

... 28. What occurs during the following stages of transcription? a. Initiation – ...
Bis2A 12.2 Eukaryotic Transcription
Bis2A 12.2 Eukaryotic Transcription

... RNA polymerase II is located in the nucleus and synthesizes all protein-coding nuclear pre-mRNAs. Eukaryotic pre-mRNAs undergo extensive processing after transcription but before translation. For clarity, this module's discussion of transcription and translation in eukaryotes will use the term mRNA ...
Biological Sequences: DNA, RNA, Protein
Biological Sequences: DNA, RNA, Protein

... proteins are composed of one or more polypeptide chains proteins composed of only one chain are called monomeric proteins (monomers) proteins composed of more than one chain are called multimeric proteins monomeric proteins may contain only one kind of protein chains when they get a preffix “homo” o ...
Protein Synthesis and Sorting
Protein Synthesis and Sorting

... • Specific regions of DNA (genes) encode message for making proteins • Genes have start and stop sites as well as a direction (5’3’) ...
Kinetic proofreading - Weizmann Institute of Science
Kinetic proofreading - Weizmann Institute of Science

... Fluorescently labeled tRNA molecules. Antibiotic inhibitors of tRNA selection. Nonhydrolizable GTP analogues. Enzymatically and chemically altered ribosome complexes GTPase activity stimulation Codon recognition (different rates, k3, for cognate state and non-cognate) GTP hydrolysis Phosphate releas ...
RNA/DNA catalysts
RNA/DNA catalysts

... Know four types of natural catalytic RNAs (group I introns, group II introns, RNase P, small self-cleaving), what reactions they perform, know basics of their secondary and tertiary structure, requirements for cofactors/metals/proteins/ATP Know details of glmS ribozyme self-cleavage Understand use o ...
Ch 12 Molecular Genetics
Ch 12 Molecular Genetics

... Eukaryote Gene Regulation  Controlling transcription: transcription factors ensure that a gene is used at the right time and that proteins are made in the right amounts  Promoters: stabilize binding of RNA polymerase  Regulatory proteins: control rate of transcription ...
answers for questions 1-6
answers for questions 1-6

... throughout  the  embryo.    This  can  be  observed  in  the  morphological  features  of  this   fly:  all  segments  will  adopt  a  fate  normally  observed  only  in  the  A5-­‐8  segments.   ...
Gene Reg Flyer 0113_D3.indd
Gene Reg Flyer 0113_D3.indd

... Figure 2. GeneSpring NGS allows you to easily visualize Methylation results. Lollipop Plot shows methylated C’s as circles colored by intensities relative to their methylation level or p-values. ...
Chapter 6 Microbial Genetics
Chapter 6 Microbial Genetics

... 3. The mechanics of translation Initiation; mRNA bumps into the small subunit and triggers the two ribosomal subunits to bind together. The first tRNA anticodon (UAC) carrying the amino acid methionine hydrogen bonds with the codon AUG on mRNA. ...
Data/hora: 06/05/2017 06:27:48 Biblioteca(s): Embrapa Gado de
Data/hora: 06/05/2017 06:27:48 Biblioteca(s): Embrapa Gado de

... The aim of this study was to screen for variability in the luteinizing hormone/choriogonadotropin receptor (LHCGR) and to determine the occurrence of LHCGR mRNA isoforms in two dairy breeds of cattle. Granulosa cells from dominant ovarian follicles were recovered from 16 Gir and 16 Holstein cows, an ...
Methods for identifying microRNA binding motifs
Methods for identifying microRNA binding motifs

... Functional importance of miRNA binding in post-transcriptional gene regulation drives effort in identifying conserved binding motifs But non-canonical motifs dominate over those based on seed sequence Experimental approaches based on RISC complex formation and immunoprecipitation help isolate miRNA- ...
Data IG and GF
Data IG and GF

... • You can chose between a set of topics broadly covering the taught material "Where a topic is assessed by a mini-project, the mini-project should be designed to take a typical student about three days. You are not permitted to withdraw from being examined on a topic once you have submitted your min ...
trp
trp

... Eukaryotic mRNAs are usually spliced,capped and tailed. Eukaryotes do NOT have operons. tRNA and rRNA expression are ...
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