Cholesterol Metabolism_MJH
... • cholic acid is the bile acid found in the largest amount in bile • cholic acid and chenodeoxycholic acid are referred to as primary bile acids • bile acids are converted to either glycine or taurine conjugates (in humans the ratio of glycine to taurine conjugates is 3:1) ...
... • cholic acid is the bile acid found in the largest amount in bile • cholic acid and chenodeoxycholic acid are referred to as primary bile acids • bile acids are converted to either glycine or taurine conjugates (in humans the ratio of glycine to taurine conjugates is 3:1) ...
Fast Protein Folding in the Hydrophobic
... Recall that two 1’s can be topological neighbors only if there is an even number of elements between them. It follows from our definition of blocks that two 1’s within a block cannot be topological neighbors. Further, any pair of 1‘s take from blocks bh and b~ may be topological neighbors only when ...
... Recall that two 1’s can be topological neighbors only if there is an even number of elements between them. It follows from our definition of blocks that two 1’s within a block cannot be topological neighbors. Further, any pair of 1‘s take from blocks bh and b~ may be topological neighbors only when ...
Functional recognition of fragmented operator sites
... The R17/MS2 coat protein serves as a translational repressor of replicase by binding to a 19 nt RNA hairpin containing the Shine–Dalgarno sequence and the initiation codon of the replicase gene. We have explored the structural features of the RNA operator site that are necessary for efficient transl ...
... The R17/MS2 coat protein serves as a translational repressor of replicase by binding to a 19 nt RNA hairpin containing the Shine–Dalgarno sequence and the initiation codon of the replicase gene. We have explored the structural features of the RNA operator site that are necessary for efficient transl ...
Amino acid transport systems of lysosomes
... plasma membrane. Furthermore, the distal N atom of lysine could be rendered quaternary (hence permanently cationic) by methylation, a change not acceptable to system y+. Gradually it became clear to us that the lysosomal system is quite unlike that of the plasma membrane (8). Indeed, if we selected ...
... plasma membrane. Furthermore, the distal N atom of lysine could be rendered quaternary (hence permanently cationic) by methylation, a change not acceptable to system y+. Gradually it became clear to us that the lysosomal system is quite unlike that of the plasma membrane (8). Indeed, if we selected ...
Stress signaling from the lumen of the endoplasmic reticulum
... linked glycan is an intermediate in the trimming process. Calnexin and calreticulin bind most avidly to monoglucosylated forms of the N-linked core structure and promote folding, delay oligomerization, and prevent degradation of some glycoproteins (Hebert et al. 1995, 1996). Prolonged association wi ...
... linked glycan is an intermediate in the trimming process. Calnexin and calreticulin bind most avidly to monoglucosylated forms of the N-linked core structure and promote folding, delay oligomerization, and prevent degradation of some glycoproteins (Hebert et al. 1995, 1996). Prolonged association wi ...
CHAPTER FOUR Pseudomonas aeruginosa INFLUENCED PLANKTONIC AND BIOFILM POPULATIONS BASED UPON
... extraction method used previously, the visualised number of protein spots here represents an increase in resolution of approximately 38%. The increased resolution of proteins may be due to the use of sample preparation solutions that, in contrast to those used in single-step extraction methods, are ...
... extraction method used previously, the visualised number of protein spots here represents an increase in resolution of approximately 38%. The increased resolution of proteins may be due to the use of sample preparation solutions that, in contrast to those used in single-step extraction methods, are ...
Document
... • The protein migration in a medium possessing a stable pH gradient • moves to a zone in the medium where the pH is equal to the isoelectric point (pI) of the protein. • the charge becomes zero • migration ceases • the protein zones are very sharp – diffusion is also counteracted • acquisition of ch ...
... • The protein migration in a medium possessing a stable pH gradient • moves to a zone in the medium where the pH is equal to the isoelectric point (pI) of the protein. • the charge becomes zero • migration ceases • the protein zones are very sharp – diffusion is also counteracted • acquisition of ch ...
Communication - Department of Molecular Physiology and Biophysics
... syntrophin triplet suggesting that all the syntrophins including α- as well as β-type may directly bind to dystrophin (Fig. 2). Previous work by Ozawa's group indicated that one of 43-DAGs was overlaid by dystrophin fusion protein containing cysteinerich and C-terminal domains (16). This interaction ...
... syntrophin triplet suggesting that all the syntrophins including α- as well as β-type may directly bind to dystrophin (Fig. 2). Previous work by Ozawa's group indicated that one of 43-DAGs was overlaid by dystrophin fusion protein containing cysteinerich and C-terminal domains (16). This interaction ...
Journal of Medical Microbiology
... A pool of heparan sulphate-binding proteins (HSBPs) from Helicobacter pylori culture supernates was obtained by sequential ammonium sulphate precipitation and af®nity chromatography on heparin-Sepharose. The chromatographic procedure yielded one major fraction that contained proteins with heparan su ...
... A pool of heparan sulphate-binding proteins (HSBPs) from Helicobacter pylori culture supernates was obtained by sequential ammonium sulphate precipitation and af®nity chromatography on heparin-Sepharose. The chromatographic procedure yielded one major fraction that contained proteins with heparan su ...
Ubiquitin and Plant Viruses, Let`s Play Together!
... and the type of chain branching, ubiquitination of proteins may have different functions in the cell. Whereas the most studied polyubiquitin Lys-48 linkage is associated with degradation by the proteasome, alternative ubiquitination events are destined for other cellular processes, such as subcellul ...
... and the type of chain branching, ubiquitination of proteins may have different functions in the cell. Whereas the most studied polyubiquitin Lys-48 linkage is associated with degradation by the proteasome, alternative ubiquitination events are destined for other cellular processes, such as subcellul ...
Basic Amino Acid Inhibition of Cell Division and
... These values are the sum of the lysine and ornithine concentrations because it was not possible to separate these two amino acids by our procedures. Physiological basis of basic aniino acid inhibition of growth Since ornithine can be converted to spermidine and other polyamines, it was possible that ...
... These values are the sum of the lysine and ornithine concentrations because it was not possible to separate these two amino acids by our procedures. Physiological basis of basic aniino acid inhibition of growth Since ornithine can be converted to spermidine and other polyamines, it was possible that ...
Systematic Analysis of Arabidopsis Organelles
... returns statistically based rank scores of overrepresented terms in the studied set. We determined overrepresented GO functions and processes of genes localized to one compartment versus all of the genes in our data set. Results are summarized in Table I and detailed results are found in the Supplem ...
... returns statistically based rank scores of overrepresented terms in the studied set. We determined overrepresented GO functions and processes of genes localized to one compartment versus all of the genes in our data set. Results are summarized in Table I and detailed results are found in the Supplem ...
G PROTEIN βγ SUBUNITS
... subunits vary between 35 and 39 kDa. If all Gβ and Gγ pairs could form, the number of potential Gβγ subunit pairs would exceed the known number of Gα s by a factor of three. While it appears that most pairs can indeed form, there are exceptions (16–19). For example, the Gβ1 subunit can combine with ...
... subunits vary between 35 and 39 kDa. If all Gβ and Gγ pairs could form, the number of potential Gβγ subunit pairs would exceed the known number of Gα s by a factor of three. While it appears that most pairs can indeed form, there are exceptions (16–19). For example, the Gβ1 subunit can combine with ...
Regulation of mTORC1 by amino acids
... Ragulator v-ATPase, GATOR (GAP activity towards Rags), and folliculin (FLCN) complexes. Increased understanding of this pathway will not only provide insight into growth control but also into the human pathologies triggered by its deregulation. Overview of mTORC1 signaling Growth is a fundamental bi ...
... Ragulator v-ATPase, GATOR (GAP activity towards Rags), and folliculin (FLCN) complexes. Increased understanding of this pathway will not only provide insight into growth control but also into the human pathologies triggered by its deregulation. Overview of mTORC1 signaling Growth is a fundamental bi ...
phlexy 10 tablets
... Phlexy 10 Tablets must be supplemented with a vitamin, mineral and trace element supplement such as Phlexy Vits Tablets. The suggested dose of Phlexy Vits Tablets is 5 tablets per day for children over the age of 11 years and adults. ...
... Phlexy 10 Tablets must be supplemented with a vitamin, mineral and trace element supplement such as Phlexy Vits Tablets. The suggested dose of Phlexy Vits Tablets is 5 tablets per day for children over the age of 11 years and adults. ...
Proteomics of spermatogenesis: from protein lists to understanding
... propose that in the case of reduced motile sperm, the overexpression of this enzyme may have been a compensatory reaction. Semenogelin I precursor was identified as four spots in our study.49 Two of these spots represented 14 kDa fragments and the other two were 17 kDa fragments. All of these spots ...
... propose that in the case of reduced motile sperm, the overexpression of this enzyme may have been a compensatory reaction. Semenogelin I precursor was identified as four spots in our study.49 Two of these spots represented 14 kDa fragments and the other two were 17 kDa fragments. All of these spots ...
mic.sgmjournals.org
... Abundance changes at 26 vs 37 6C were observed for many outer-membrane (OM) proteins. The cell adhesion protein Ail (y1324) and three putative small b-barrel OM proteins (y1795, y2167 and y4083) were strongly increased at 37 6C. The Ail/Lom family protein y1682 (OmpX) was strongly increased at 26 6C ...
... Abundance changes at 26 vs 37 6C were observed for many outer-membrane (OM) proteins. The cell adhesion protein Ail (y1324) and three putative small b-barrel OM proteins (y1795, y2167 and y4083) were strongly increased at 37 6C. The Ail/Lom family protein y1682 (OmpX) was strongly increased at 26 6C ...
Sequence elements of the fusion peptide of human respiratory
... previous section. Culture supernatants were harvested 48 h postinfection, cleared of cell debris and concentrated 100-fold and bufferexchanged to PBS by filtration through polyethersulfone membranes (Vivaflow; Sartorius) of 100 kDa exclusion pore size. The concentrates were loaded onto immunoaffinit ...
... previous section. Culture supernatants were harvested 48 h postinfection, cleared of cell debris and concentrated 100-fold and bufferexchanged to PBS by filtration through polyethersulfone membranes (Vivaflow; Sartorius) of 100 kDa exclusion pore size. The concentrates were loaded onto immunoaffinit ...
Ingredient of the Month - American Culinary Federation
... Protein: As a plant source of protein, walnuts offer protein without the saturated fat and cholesterol associated with animal sources of protein. Protein from foods is broken down into amino acids that are later used for a variety of bodily functions, such as transporting nutrients and oxygen in the ...
... Protein: As a plant source of protein, walnuts offer protein without the saturated fat and cholesterol associated with animal sources of protein. Protein from foods is broken down into amino acids that are later used for a variety of bodily functions, such as transporting nutrients and oxygen in the ...
Effect of the addition of CMC on the aggregation behaviour
... of CMC could be also attributed to its characteristic to form electrostatic complexes with proteins (Shih, 1994). However, the effect of CMC can also be explain by one of the basic function of CMC that is to impart viscosity to the aqueous phase, thereby stabilising the other ingredients. ...
... of CMC could be also attributed to its characteristic to form electrostatic complexes with proteins (Shih, 1994). However, the effect of CMC can also be explain by one of the basic function of CMC that is to impart viscosity to the aqueous phase, thereby stabilising the other ingredients. ...
Proteases and proteolytic cleavage of storage
... Hurkman, 1978). It has also been postulated that the prolamin (gliadin) in wheat is directly transferred to storage vacuoles without passing the Golgi apparatus (Galili et al, 1995). Several of the globulin polypeptides are modified by glycosylation in the ER and Golgi apparatus and/or undergo addit ...
... Hurkman, 1978). It has also been postulated that the prolamin (gliadin) in wheat is directly transferred to storage vacuoles without passing the Golgi apparatus (Galili et al, 1995). Several of the globulin polypeptides are modified by glycosylation in the ER and Golgi apparatus and/or undergo addit ...
Protein (nutrient)
Proteins are essential nutrients for the human body. They are one of the building blocks of body tissue, and can also serve as a fuel source. As a fuel, proteins contain 4 kcal per gram, just like carbohydrates and unlike lipids, which contain 9 kcal per gram. The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition.Proteins are polymer chains made of amino acids linked together by peptide bonds. During human digestion, proteins are broken down in the stomach to smaller polypeptide chains via hydrochloric acid and protease actions. This is crucial for the synthesis of the essential amino acids that cannot be biosynthesized by the body.There are nine essential amino acids which humans must obtain from their diet in order to prevent protein-energy malnutrition. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine. There are five dispensable amino acids which humans are able to synthesize in the body. These five are alanine, aspartic acid, asparagine, glutamic acid and serine. There are six conditionally essential amino acids whose synthesis can be limited under special pathophysiological conditions, such as prematurity in the infant or individuals in severe catabolic distress. These six are arginine, cysteine, glycine, glutamine, proline and tyrosine.Humans need the essential amino acids in certain ratios. Some protein sources contain amino acids in a more or less 'complete' sense. This has given rise to various ranking systems for protein sources, as described in the article.Animal sources of protein include meats, dairy products, fish and eggs. Vegan sources of protein include whole grains, pulses, legumes, soy, and nuts. Vegetarians and vegans can get enough essential amino acids by eating a variety of plant proteins. It is commonly believed that athletes should consume a higher-than-normal protein intake to maintain optimal physical performance.