The HSSP database of protein structure–sequence
... protein evolution, folding and design. CONTENT AND FORMAT OF THE DATABANK For each protein in PDB, with identifier xxxx (like: 1PPT, 5PCY), there is an ASCII (text) file xxxx.HSSP which contains: (i) the primary sequence of the protein of known structure, along with the derived secondary structure a ...
... protein evolution, folding and design. CONTENT AND FORMAT OF THE DATABANK For each protein in PDB, with identifier xxxx (like: 1PPT, 5PCY), there is an ASCII (text) file xxxx.HSSP which contains: (i) the primary sequence of the protein of known structure, along with the derived secondary structure a ...
Biology
... 27. (1pt) The “guardian angel gene” codes for a protein that will destroy the cell that it is in, if it turns cancerous. If the mutation in the previous question occurs in p53, how many of the cells resulting from mitosis of this cell will carry the mutation? ...
... 27. (1pt) The “guardian angel gene” codes for a protein that will destroy the cell that it is in, if it turns cancerous. If the mutation in the previous question occurs in p53, how many of the cells resulting from mitosis of this cell will carry the mutation? ...
Powerpoint Presentation: The Origins of Life
... The polynucleotides directed the synthesis of the polypeptides Today it is clear that information only flows from polynucleotides to polypeptides. Translation had started. ...
... The polynucleotides directed the synthesis of the polypeptides Today it is clear that information only flows from polynucleotides to polypeptides. Translation had started. ...
The 14-3-3 proteins in regulation of cellular metabolism - BORA
... interactome of the 14-3-3 proteins and its regulation by protein phosphorylation events suggest a fundamental function of these proteins in signaling related to cellular metabolic states. The archetypical peptide sequence requirements for binding to 14-33 have been known for a long time [9] and have ...
... interactome of the 14-3-3 proteins and its regulation by protein phosphorylation events suggest a fundamental function of these proteins in signaling related to cellular metabolic states. The archetypical peptide sequence requirements for binding to 14-33 have been known for a long time [9] and have ...
visualization, comparison and analysis of 2D maps of protein structure
... protein. Analysis of incomplete structures that differ in length (e.g. crude fold-recognition models that exhibit deletions or crystallographic structures with disordered parts) is however possible, as long as the corresponding residues retain the same index number in all models. PROTMAP2D allows an ...
... protein. Analysis of incomplete structures that differ in length (e.g. crude fold-recognition models that exhibit deletions or crystallographic structures with disordered parts) is however possible, as long as the corresponding residues retain the same index number in all models. PROTMAP2D allows an ...
Lysinuric protein intolerance: one gene, many
... amino acids. Inherited renal aminoacidurias arise as a result of mutations inactivating apical or basolateral transport systems. Although aminoacidurias are diagnosed by urine amino acid analysis, most of the disorders affect both intestinal and renal transport. In the intestine, peptide transporter ...
... amino acids. Inherited renal aminoacidurias arise as a result of mutations inactivating apical or basolateral transport systems. Although aminoacidurias are diagnosed by urine amino acid analysis, most of the disorders affect both intestinal and renal transport. In the intestine, peptide transporter ...
Title goes here - VideoLectures.NET
... then the function of this ORF is ”pheromone response, mating type determination, sex-specific proteins" ...
... then the function of this ORF is ”pheromone response, mating type determination, sex-specific proteins" ...
This presentation follows on from the talk presented
... In Mascot Insight, we have implemented a report which allows you to use the protein hit sequences from a selected search result to carry out a BLAST like sequence homology search using de novo solutions, in order to try to find additional possible matches to spectra from your dataset, drilling down ...
... In Mascot Insight, we have implemented a report which allows you to use the protein hit sequences from a selected search result to carry out a BLAST like sequence homology search using de novo solutions, in order to try to find additional possible matches to spectra from your dataset, drilling down ...
ap nucleic acids, proteins and enzymes
... R groups on the surface may form weak interactions (e.g., hydrogen bonds) with groups on the surface of another molecule. This can change the tertiary structure and thus the shape of the protein. Protein structure can also be modified by covalent bonding of a chemical group to the side chain of one ...
... R groups on the surface may form weak interactions (e.g., hydrogen bonds) with groups on the surface of another molecule. This can change the tertiary structure and thus the shape of the protein. Protein structure can also be modified by covalent bonding of a chemical group to the side chain of one ...
PoL2e Ch03 Lecture-Nucleic Acids, Proteins, and Enzymes
... R groups on the surface may form weak interactions (e.g., hydrogen bonds) with groups on the surface of another molecule. This can change the tertiary structure and thus the shape of the protein. Protein structure can also be modified by covalent bonding of a chemical group to the side chain of one ...
... R groups on the surface may form weak interactions (e.g., hydrogen bonds) with groups on the surface of another molecule. This can change the tertiary structure and thus the shape of the protein. Protein structure can also be modified by covalent bonding of a chemical group to the side chain of one ...
CSE 181 Project guidelines - Computer Science and Engineering
... • This causes the protein to start folding and adopting its functional structure • Proteins may fold in reaction to some ions, and several separate chains of peptides may join together through their hydrophobic and hydrophilic amino acids to form a polymer ...
... • This causes the protein to start folding and adopting its functional structure • Proteins may fold in reaction to some ions, and several separate chains of peptides may join together through their hydrophobic and hydrophilic amino acids to form a polymer ...
CHAPTER 15
... the possible mRNA codons. FIGURE 15.15 Concept check: Explain how mRNA plays a role in all three stages. Answer: A site in mRNA promotes the binding of the mRNA to the ribosome. The codons are needed during elongation to specify the polypeptide sequence. The stop codon is needed to terminate transcr ...
... the possible mRNA codons. FIGURE 15.15 Concept check: Explain how mRNA plays a role in all three stages. Answer: A site in mRNA promotes the binding of the mRNA to the ribosome. The codons are needed during elongation to specify the polypeptide sequence. The stop codon is needed to terminate transcr ...
Modeling RNA Molecules
... the number of ncRNAs has exploded and appears to scale with biological complexity (Taft et al. 2007). Evidence is building that many of these ncRNAs, like those involved in splicing and translation, which have been known for many years, function at least in part by forming complex 3D structures to i ...
... the number of ncRNAs has exploded and appears to scale with biological complexity (Taft et al. 2007). Evidence is building that many of these ncRNAs, like those involved in splicing and translation, which have been known for many years, function at least in part by forming complex 3D structures to i ...
Nutrition intervention in sarcopenia
... Jeffrey Stout: There are studies with head-to-head comparisons of milk proteins (animal source) and soy proteins (vegetable source). The milk proteins were far more anabolic, though soy proteins are still anabolic and still able to accelerate the benefits of exercise, just not to the same extent as ...
... Jeffrey Stout: There are studies with head-to-head comparisons of milk proteins (animal source) and soy proteins (vegetable source). The milk proteins were far more anabolic, though soy proteins are still anabolic and still able to accelerate the benefits of exercise, just not to the same extent as ...
figure 25.1
... FIGURE 25.6 Hypothetical example of the importance of genewide genotype combinations. Three adjacent single nucleotide polymorphisms (SNPs) in different parts of a gene are shown for two individuals (A and B indicated at the bottom). The subjects, A and B, have identical genotypes, i.e., they are b ...
... FIGURE 25.6 Hypothetical example of the importance of genewide genotype combinations. Three adjacent single nucleotide polymorphisms (SNPs) in different parts of a gene are shown for two individuals (A and B indicated at the bottom). The subjects, A and B, have identical genotypes, i.e., they are b ...
GENE NOMENCLATURE OF DIFFERENT TYPES OF SPINOCEREBELLAR ATAXIA (SCA) AND
... alignments of these sequences, and then calculates from the alignment the tolerance index (from 0 to 1) for all possible substitutions at each position. The higher a tolerance index, the less functional impact a particular amino acid substitution is likely to have [9-14]. Prediction of functional mo ...
... alignments of these sequences, and then calculates from the alignment the tolerance index (from 0 to 1) for all possible substitutions at each position. The higher a tolerance index, the less functional impact a particular amino acid substitution is likely to have [9-14]. Prediction of functional mo ...
Cloning and characterization of CmGPD1, the Candida magnoliae
... No claim to original Korean government works ...
... No claim to original Korean government works ...
Receptors and Hormone Action
... • RNA polymerase added to chromatin to bind initiation sites, then • rifampicin added to bind and inhibits excess RNA polymerase •Nucleotides added to start transcription, •Result : only one copy is made as after that RNA polymerases are inhibited by rifampicin ...
... • RNA polymerase added to chromatin to bind initiation sites, then • rifampicin added to bind and inhibits excess RNA polymerase •Nucleotides added to start transcription, •Result : only one copy is made as after that RNA polymerases are inhibited by rifampicin ...
The cDNA-deduced Amino Acid Sequence for
... letter X. A lysine residue (small letters) has been placed at the amino end of each peptide because of the site-specific cleavageof endoproteinase lysine C. The peptides have been aligned to emphasize their similarity. Each peptide contains at least one QL combination (boxed) which is surrounded by ...
... letter X. A lysine residue (small letters) has been placed at the amino end of each peptide because of the site-specific cleavageof endoproteinase lysine C. The peptides have been aligned to emphasize their similarity. Each peptide contains at least one QL combination (boxed) which is surrounded by ...
Domain fusion between SNF1-related kinase subunits during plant
... sensitive to glucose-dependent signals in yeast. Interestingly, a deletion of the KIS domain from ZmAKINβγ-1 resulted in stronger binding to AKIN11 in the presence of glucose, one possibility is that this domain may affect the regulation of subunit interactions by glucose. The ZmAKINβγ-binding site ...
... sensitive to glucose-dependent signals in yeast. Interestingly, a deletion of the KIS domain from ZmAKINβγ-1 resulted in stronger binding to AKIN11 in the presence of glucose, one possibility is that this domain may affect the regulation of subunit interactions by glucose. The ZmAKINβγ-binding site ...
Model for crossing over and gene conversion
... This model fits the double strand breakage and gene conversion data. The main points are: Crossing over involves a double strand break in one double helix; strand invasion, etc. will lead to a D-loop, to heteroduplexes.and to the Holliday junctions; the Holliday junctions may be resolved into either ...
... This model fits the double strand breakage and gene conversion data. The main points are: Crossing over involves a double strand break in one double helix; strand invasion, etc. will lead to a D-loop, to heteroduplexes.and to the Holliday junctions; the Holliday junctions may be resolved into either ...
2.4 Proteins
... • A polypeptide is a polymer of amino acids • Polypeptides range in length from a few monomers to more than a thousand • Each polypeptide has a unique linear sequence of amino ...
... • A polypeptide is a polymer of amino acids • Polypeptides range in length from a few monomers to more than a thousand • Each polypeptide has a unique linear sequence of amino ...
Protein Functional Annotation - Institute for Genome Sciences
... assessing available evidence and reaching a conclusion about what you think the protein is doing in the cell and why.! •! Functional annotations should only be as specific as the supporting evidence allows! •! All evidence that led to the annotation conclusions that were made must be stored.! •! In ...
... assessing available evidence and reaching a conclusion about what you think the protein is doing in the cell and why.! •! Functional annotations should only be as specific as the supporting evidence allows! •! All evidence that led to the annotation conclusions that were made must be stored.! •! In ...
trypsin inhibitor and castor-bean (Ricinus communis) storage protein
... role appears to be a defence mechanism of plants against various pests and parasites (Ryan, 1973). Some inhibit extracellular proteinases produced by phytopathogens, such as Fusarium solani (Mosolov et al., 1976), possibly to prevent invasion and growth of the micro-organisms. On the other hand, man ...
... role appears to be a defence mechanism of plants against various pests and parasites (Ryan, 1973). Some inhibit extracellular proteinases produced by phytopathogens, such as Fusarium solani (Mosolov et al., 1976), possibly to prevent invasion and growth of the micro-organisms. On the other hand, man ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.