Sleep Neurobiology from a Clinical Perspective
... NE is produced by several brainstem nuclei and may help generate arousal during conditions that require high attention or activation of the sympathetic nervous system. The major source of NE to the forebrain is the locus coeruleus (LC), an elongated nucleus just beneath the floor of the fourth ventr ...
... NE is produced by several brainstem nuclei and may help generate arousal during conditions that require high attention or activation of the sympathetic nervous system. The major source of NE to the forebrain is the locus coeruleus (LC), an elongated nucleus just beneath the floor of the fourth ventr ...
sleep disturbances associated with neuropsychiatric disease
... Several observations suggest important links between sleep and mental disorders. From a psychological perspective, it has long been thought that trouble sleeping is related to a troubled mind, an intrusion of mental activity into the quiescence of sleep. Historically, this vein has fueled much of th ...
... Several observations suggest important links between sleep and mental disorders. From a psychological perspective, it has long been thought that trouble sleeping is related to a troubled mind, an intrusion of mental activity into the quiescence of sleep. Historically, this vein has fueled much of th ...
Center for Epidemiologic Studies Depression Scale (CES-D)
... There is no regular relationship between my mood and the time of day. My mood often relates to the time of day because of environmental events (e.g., being alone, working). In general, my mood is more related to the time of day than to environmental events. My mood is clearly and predictably better ...
... There is no regular relationship between my mood and the time of day. My mood often relates to the time of day because of environmental events (e.g., being alone, working). In general, my mood is more related to the time of day than to environmental events. My mood is clearly and predictably better ...
Effect of Lesions of the Ventrolateral Preoptic Nucleus on NREM and
... inhibition of these neurons by the VLPO is thought to play a major role in causing sleep. Steininger et al. (1997) and Yang and Hatton (1997) have shown that electrical stimulation in the VLPO region causes GABAA receptor-mediated hyperpolarization and inhibition of TMN neurons in brain slices. Thes ...
... inhibition of these neurons by the VLPO is thought to play a major role in causing sleep. Steininger et al. (1997) and Yang and Hatton (1997) have shown that electrical stimulation in the VLPO region causes GABAA receptor-mediated hyperpolarization and inhibition of TMN neurons in brain slices. Thes ...
Chantix (Varenicline) http://www
... - Denial that there are problems - Misbelieve that “I can handle it on my own” - Using drugs, alcohol to regulate mood or sleep: these might initially help some but lead to problems and worsening of PTSD symptoms over time. - Stimulants: Nicotine from cigarettes, caffeine from coffee tea and soda, “ ...
... - Denial that there are problems - Misbelieve that “I can handle it on my own” - Using drugs, alcohol to regulate mood or sleep: these might initially help some but lead to problems and worsening of PTSD symptoms over time. - Stimulants: Nicotine from cigarettes, caffeine from coffee tea and soda, “ ...
Nightmares and their treatment options
... Children having nightmares are most frequently comforted by their mothers. If children feel secure, nightmares are rare and often related to terrifying events. They may be more frequent after return from a hospital or summer camp. They are probably best solved by the mother’s safe embrace and genera ...
... Children having nightmares are most frequently comforted by their mothers. If children feel secure, nightmares are rare and often related to terrifying events. They may be more frequent after return from a hospital or summer camp. They are probably best solved by the mother’s safe embrace and genera ...
Author`s personal copy - Sleep, Stress, and Memory Lab
... not bound to the originating context). Third, there are “how to” memories for the various skills, procedures, and habits that we acquire through experience. Because these memories are not so easily made explicit and are usually only evident in behavior, they are referred to as procedural or implicit ...
... not bound to the originating context). Third, there are “how to” memories for the various skills, procedures, and habits that we acquire through experience. Because these memories are not so easily made explicit and are usually only evident in behavior, they are referred to as procedural or implicit ...
Idiopathic Hypersomnia: A Study of 77 Cases
... other siblings. The mean age of diagnosis was 30 years. There was no precipitant in the majority of cases, although 3 subjects reported a transient viral illness at the time of symptom onset, and 1 subject reported onset of symptoms over a day. The mean ESS score at initial presentation prior to tre ...
... other siblings. The mean age of diagnosis was 30 years. There was no precipitant in the majority of cases, although 3 subjects reported a transient viral illness at the time of symptom onset, and 1 subject reported onset of symptoms over a day. The mean ESS score at initial presentation prior to tre ...
Distinguishing rumination from worry in clinical insomnia
... Zachariae, 2003) and worry have purported roles in this cycle (Harvey, 2002) but there have been few empirical attempts to clarify how these roles are similar or different. It has been suggested that even though both rumination and worry may involve a repetitive thought process (Segerstrom et al., 2 ...
... Zachariae, 2003) and worry have purported roles in this cycle (Harvey, 2002) but there have been few empirical attempts to clarify how these roles are similar or different. It has been suggested that even though both rumination and worry may involve a repetitive thought process (Segerstrom et al., 2 ...
Facial Nerve Paralysis presentation (NXPowerLite)
... – Traps nerve in narrow confines of fallopian canal ...
... – Traps nerve in narrow confines of fallopian canal ...
Use of clonidine in children with autism spectrum disorders Xue Ming
... have sleep initiation difficulty and clonidine was given for the lengthy night awakening. Clonidine did slightly reduce his sleep initiation time as well. Although two subjects still suffered from prolonged sleep initiation (>1 h), the caregivers of both subjects expressed satisfaction with the effect o ...
... have sleep initiation difficulty and clonidine was given for the lengthy night awakening. Clonidine did slightly reduce his sleep initiation time as well. Although two subjects still suffered from prolonged sleep initiation (>1 h), the caregivers of both subjects expressed satisfaction with the effect o ...
A Critical Period of Sleep for Development of Courtship Circuitry and
... brain patterning (1). Average daily sleep amounts are highest early in development across multiple species (1–4), and human studies have indeed demonstrated that impaired sleep during critical periods of development can have severe and longlasting consequences (5–7). Yet it remains unknown whether s ...
... brain patterning (1). Average daily sleep amounts are highest early in development across multiple species (1–4), and human studies have indeed demonstrated that impaired sleep during critical periods of development can have severe and longlasting consequences (5–7). Yet it remains unknown whether s ...
Brain Electrical Activity During Waking and Sleep States
... * Desynchronization is an improper term to characterize active state since cognitive operations are associated with fast frequency (gamma) synchronized oscillations in large scale networks. ...
... * Desynchronization is an improper term to characterize active state since cognitive operations are associated with fast frequency (gamma) synchronized oscillations in large scale networks. ...
Why We Sleep: The Temporal Organization of
... periods of hyperpolarization (down phase) within large areas of the cortex. Slow-wave sleep intensity is often measured by EEG power in the delta frequency range. REM sleep is also called paradoxical sleep. EEG is desynchronized and hippocampal theta rhythms are present. Muscle atonia and dreaming a ...
... periods of hyperpolarization (down phase) within large areas of the cortex. Slow-wave sleep intensity is often measured by EEG power in the delta frequency range. REM sleep is also called paradoxical sleep. EEG is desynchronized and hippocampal theta rhythms are present. Muscle atonia and dreaming a ...
Duration of sleep contributes to next-day pain report in the
... elevated risk for the future development of pain complaints over time frames from as short as 1 year to as long as 28 years [8,11,23,26]. Moreover, our recent reports from our group (Smith et al. [30]) and others [4] have indicated that the development of symptoms of insomnia (i.e., disrupted sleep) ...
... elevated risk for the future development of pain complaints over time frames from as short as 1 year to as long as 28 years [8,11,23,26]. Moreover, our recent reports from our group (Smith et al. [30]) and others [4] have indicated that the development of symptoms of insomnia (i.e., disrupted sleep) ...
What Keeps Us Awake: the Neuropharmacology of Stimulants and
... hypothalamic-pituitary-adrenal axis.35-37 A key contribution in the etiology of narcolepsy was provided by several studies linking the hypocretin/orexin system to this disease. First, two different animal models with an impaired hypocretin/orexin system—genetic narcoleptic dogs with a mutation in th ...
... hypothalamic-pituitary-adrenal axis.35-37 A key contribution in the etiology of narcolepsy was provided by several studies linking the hypocretin/orexin system to this disease. First, two different animal models with an impaired hypocretin/orexin system—genetic narcoleptic dogs with a mutation in th ...
Spontaneous Spike Activity of Spinoreticular Tract Neurons During
... 1Z3, Canada Abstract: Sleep mentation studies infer that pain sensation in humans may be reduced during active REM sleep. However, to provide a mechanistic explanation for this phenomenon, few, if any neurophysiological studies have been performed at the lumbar level from neurons comprising classica ...
... 1Z3, Canada Abstract: Sleep mentation studies infer that pain sensation in humans may be reduced during active REM sleep. However, to provide a mechanistic explanation for this phenomenon, few, if any neurophysiological studies have been performed at the lumbar level from neurons comprising classica ...
Recognizing and Managing Shift Work Disorder, an
... Circadian rhythm sleep disorders can occur when there is a misalignment between the timing of sleep and the desired sleep/wake cycle, leading to impaired functioning, safety issues, and associated morbidities.[1] Shift work generally requires an individual to be awake and functioning when the biolog ...
... Circadian rhythm sleep disorders can occur when there is a misalignment between the timing of sleep and the desired sleep/wake cycle, leading to impaired functioning, safety issues, and associated morbidities.[1] Shift work generally requires an individual to be awake and functioning when the biolog ...
Brain Electrical Activity During Waking and Sleep States
... * Desynchronization is an improper term to characterize active state since cognitive ...
... * Desynchronization is an improper term to characterize active state since cognitive ...
Generation of Rapid Eye Movements during Paradoxical Sleep in
... setting. Participants were selected for the third night if they could maintain 20 min of continuous stage II sleep, SWS, and PS on both habituation nights. During the third night, 12 PET scans were performed both during various stages of sleep when polysomnography showed steady characteristic sleep ...
... setting. Participants were selected for the third night if they could maintain 20 min of continuous stage II sleep, SWS, and PS on both habituation nights. During the third night, 12 PET scans were performed both during various stages of sleep when polysomnography showed steady characteristic sleep ...
Physiological Predictors of Response to Exposure,
... Moreover, chronic nightmares (CN) may be a significant maintaining factor of psychological distress, because successful treatment of CN with cognitive behavioral therapy results in the reduction of symptoms of PTSD, depression, and nightmare-related panic.6-8 Therefore, CN may pose a pernicious heal ...
... Moreover, chronic nightmares (CN) may be a significant maintaining factor of psychological distress, because successful treatment of CN with cognitive behavioral therapy results in the reduction of symptoms of PTSD, depression, and nightmare-related panic.6-8 Therefore, CN may pose a pernicious heal ...
Association of Psychiatric Disorders and Sleep Apnea in a Large
... hypoxemia, and to some extent sleep fragmentation, reportedly can cause depressive symptoms.8 By this definition, depression related to sleep apnea would be considered as a depression secondary to a general medical condition.22 In contrast, excessive daytime sleepiness and fatigue resulting from sle ...
... hypoxemia, and to some extent sleep fragmentation, reportedly can cause depressive symptoms.8 By this definition, depression related to sleep apnea would be considered as a depression secondary to a general medical condition.22 In contrast, excessive daytime sleepiness and fatigue resulting from sle ...
A mathematical model on REM-NREM cycle
... • sleep-wake homeostasis, or Process S, the accumulation of hypnogenic (sleep-inducing) substances in the brain, which generates a homeostatic sleep drive. Both of these processes are influenced to some extent by the genes of the individual. In addition, various external factors can also have a dire ...
... • sleep-wake homeostasis, or Process S, the accumulation of hypnogenic (sleep-inducing) substances in the brain, which generates a homeostatic sleep drive. Both of these processes are influenced to some extent by the genes of the individual. In addition, various external factors can also have a dire ...
Guidelines for the Assessment and Management of Patients with
... Charles Dickens. “The Fat Boy Joe” and REM. The physiological roles of non-REM and REM sleep appear fundamentally different in that there is evidence that non-REM sleep, especially slow-wave sleep, is primarily concerned with restorative functions, whereas REM sleep appears to be more concerned with ...
... Charles Dickens. “The Fat Boy Joe” and REM. The physiological roles of non-REM and REM sleep appear fundamentally different in that there is evidence that non-REM sleep, especially slow-wave sleep, is primarily concerned with restorative functions, whereas REM sleep appears to be more concerned with ...
Mammalian Sleep
... seeds of both sleep states. Furthermore, there is now unequivocal evidence of REM sleep in another of the three surviving monotremes, the platypus, occupying 6 to 8 hours per day (more than in any other mammal) and accompanied by eye movements, atonia, twitching, and an elevated response threshold, ...
... seeds of both sleep states. Furthermore, there is now unequivocal evidence of REM sleep in another of the three surviving monotremes, the platypus, occupying 6 to 8 hours per day (more than in any other mammal) and accompanied by eye movements, atonia, twitching, and an elevated response threshold, ...
Sleep paralysis
Sleep paralysis is a phenomenon in which a person either during falling asleep (Hypnagogia) or awakening (Hypnopompic), temporarily experiences an inability to move, speak, or react. It is a transitional state between wakefulness and sleep, characterized by muscle atonia (muscle weakness). It is often accompanied by terrifying hallucinations (such as an intruder in the room) to which one is unable to react due to paralysis, and physical experiences (such as strong current running through the upper body). One hypothesis is that it results from disrupted REM sleep, which normally induces complete muscle atonia to prevent sleepers from acting out their dreams. Sleep paralysis has been linked to disorders such as narcolepsy, migraines, anxiety disorders, and obstructive sleep apnea; however, it can also occur in isolation.