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Volume 1, Number7
Volume 1, Number7

... itself been associated with cognitive deficits. Consequently, it has been difficult to tease apart the relative contributions of MDMA and marijuana to the cognitive differences between the MDMA and control groups. It is possible that MDMA and marijuana exert mechanistically independent effects on th ...
Obesity - Moodle Lille 2
Obesity - Moodle Lille 2

... • short-term (usually interpreted as 'up to 12 weeks') to treat obesity, while following nonpharmacological approaches to weight loss such as healthy dieting and exercise ...
Non-approved or off-label indications
Non-approved or off-label indications

... What gives? Non-approved or off-label indications: a panacea or quagmire? Medications are routinely used in clinical practice. Prescribers often become comfortable with a range of medications they see used during their training. This often forms the basis for their prescribing habits when they start ...
RefresherMedical-7PoisoningsOverdose
RefresherMedical-7PoisoningsOverdose

... • Can be lethal with other CNS depressants especially alcohol • Look like other CNS depressant overdoses ...
Off-Label Paediatric Drug Use for Juvenile Depression and the
Off-Label Paediatric Drug Use for Juvenile Depression and the

... Medicinal Products for Human Use (CHMP) completed a data review of Prozac5 and gave a positive opinion to extend its use to children and adolescents provided that additional studies were conducted to ensure Prozac’s safety profile remained acceptable. Prozac use in children aged eight and over must ...
Aniracetam - Supplement Support Homepage
Aniracetam - Supplement Support Homepage

... be some basic background information concerning the racetam class of drugs, as well as some background and definition on the word “nootropic”itself. When one thinks of racetams, well those who do think of racetams, they usually think first of piracetam. This is expected, as it is the prototypical r ...
Tough Anesthesia Cases - VCA Specialty Animal Hospitals
Tough Anesthesia Cases - VCA Specialty Animal Hospitals

...  Pre‐op blood/Rads/ECG/BP normal Anesthetic plan:  1. Premed: Hydro (0.1 mg/kg) + Midazolam (0.1mg/kg) 2. Induction: Midazolam (0.1mg/kg) + Propofol to effect ...
STOMACH SPECIFIC MUCOADHESIVE MICROSPHERES AS CONTROLLED DRUG DELIVERY SYSTEM-A REVIEW  Review Article
STOMACH SPECIFIC MUCOADHESIVE MICROSPHERES AS CONTROLLED DRUG DELIVERY SYSTEM-A REVIEW Review Article

... to store and mix food with gastric secretions before emptying its load (chyme) through the pyloric sphincter and into the small intestine at a controlled rate suitable for digestion and absorption [11]. When empty, the stomach occupies a volume of about 50 ml, but this may increase to as much as 1 l ...
cost effective analysis of commonly used topical drugs in
cost effective analysis of commonly used topical drugs in

... In this study, commonly prescribed antibiotics were Moxifloxacin, Gatifloxacin and Tobramycin. Most cost effective drug was Tobramycin (Toram-Rs 26/- per bottle).-TABLE 2. Ocular infections can be vision threatening, and hence generally broad spectrum antibiotics are prescribed for bacterial conjunc ...
Targeting cell signaling pathways for drug discovery
Targeting cell signaling pathways for drug discovery

... to the human disease. This is followed in turn by identification of specific chemical- or antibodybased small molecule modulators or inhibitors of the target. Target validation is a complex and extremely difficult process [Tobert, 2003], and extremely few disease-relevant targets are amenable to dru ...
TOPIC OUTLINE
TOPIC OUTLINE

... culminates in the secretion of H+ by parietal cells The most important mechanism of ion-gradient generation is through the K+/H+-ATPase Pump or the Proton Pump (most hardworking pump in the body); this generates the largest known ion gradient in vertebrates with intracellular pH of 7.3 and intracana ...
Other uses
Other uses

... •Adverse effects could be significant but warnings in the literature may be exaggerated •Reasonable evidence for some improvement in ED and sexual dysfunction associated with SSRI therapy •Studies needed to compare with Viagra etc •Rx drug, usually 15-30mg/d used; avoid >30mg/d ...
Sleeping Drugs
Sleeping Drugs

... Sedative antihistamine drugs in addition to their antihistamine effects produce drowsiness as a side-effect and this is sometimes used to promote sleep. They may be useful for promoting sleep in patients with skin irritations or allergic symptoms. There are dangers in using them to treat insomnia be ...
J.Grevel 25.05.07
J.Grevel 25.05.07

... PKPD modeling in mice – Population approach: Population PD model using predicted individual concentrations at the time of the effect measurement Individual concentrations are predicted based on: -the dose given at the PD experiment -the gender and weight of the mouse -the time of the effect measurem ...
Limitations of Antiretroviral Therapy
Limitations of Antiretroviral Therapy

...  This results in mutations or errors in the genetic material of the virus which make the structure of the offspring virus slightly different to that of the parent virus  Some of these mutations will result in an increased ability of the virus to grow in the presence of antiretroviral drugs ...
Identifying and establishing consensus on the most important safety
Identifying and establishing consensus on the most important safety

... having been achieved if 90% or more of the panel members rated that statement as ‘important’ or ‘very important’ after the second round. Based on advice from the local research ethics committee, we did not need ethical approval for this study. The two-round Delphi process was conducted during the fir ...
Name: Hoh Chun Onn Roll No: EPC/26/007/10 EPCE Group 2
Name: Hoh Chun Onn Roll No: EPC/26/007/10 EPCE Group 2

... The three areas of comparison for these two COX-2 inhibitor drugs will be (1) cost, (2) recommended dosage and (3) ulcer frequency. Cost. Since many prescription-drug insurance plans cover the cost of a month's supply, price comparisons are based on a 30-day supply. Costs can vary somewhat from one ...
No Slide Title
No Slide Title

... 3. Anxiogenic-like responses in the plus maze and defensive burying tests 4. Escalation in drug self-administration with prolonged access ...
Document
Document

...  Insulin, warfarin and digoxin account for one-third of ER visits due to ADRs in the elderly. This points out that although a medication might be justified we are not appropriately monitoring these for side-effects such as blood glucose, INRs and serum levels or ECGs. ...
Psychopharmacology of Mood Disorders
Psychopharmacology of Mood Disorders

... Psychopharmacology of Mood Disorders Dr. Bill Lyndon Department of Psychological Medicine, University of Sydney ...
Effects of oral contraceptives - Microgynon and Primolut
Effects of oral contraceptives - Microgynon and Primolut

... Oral contraceptives such as Microgynon a combined pill (0.15mg levonorgestrel and 0.03mg ethinylestradiol) and Primolut -N a mini pill (5mg norethisterone) were investigated for their Invivo effects on wistar albino rat plasma creatinine levels. Test results showed that the drugs raised plasma creat ...
EVALUATION OF PHYSICAL PROPERTIES OF JIT-TRA-ROM FAST DISINTEGRATING TABLETS
EVALUATION OF PHYSICAL PROPERTIES OF JIT-TRA-ROM FAST DISINTEGRATING TABLETS

... from a sleeping disorder. Insomnia is the most common sleeping disorder, and it has been a major public health problem, affecting up to 48% of adults [1]. This problem has many consequences that may impact on health and quality of life, including development of depression, high costs of treatment an ...
(part 1)
(part 1)

... what similar after properties to basis: Vaseline -Vaseline oil, fatty basis drupaceous butter. Liquids take so much, how many matters.  If total amount of these substances more than 5 %, they are ground with an even amount to mass of dry substances of molten basis.  In hydrophilic bases these subs ...
IN SILICO QUINAZOLINONES AS NMDA RECEPTOR INHIBITORS FOR ANTICONVULSANT ACTIVITY  Research Article
IN SILICO QUINAZOLINONES AS NMDA RECEPTOR INHIBITORS FOR ANTICONVULSANT ACTIVITY Research Article

... drugs. Ten mice of either sex with a weight of 35 to 40 g were treated with test compound or the standard (e.g. Memantine 15mg/kg s.c.) by oral or subcutaneous administration. Controls received the vehicle only. 30 minutes after s.c. or 60 minutes after p.o treatment the animals are injected with su ...
Structure-based drug design strategies in medicinal
Structure-based drug design strategies in medicinal

... The search for new biologically active molecules from large compound databases by means of computer-assisted methods is a process known as virtual screening. VS methods have rapidly become an essential component of the modern drug discovery process [24-27]. Structure-based virtual screening (SBVS) a ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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